Personal profile
Research interests
Our group is interested in developing predictive and prognostic biomarkers in patients with non-small cell lung cancer(NSCLC). We have identified a 64 gene signature that accurately predicts the outcomes of patients with resected early stage NSCLC. We are in the process of developing a q RT PCR assay that could be performed in formalin fixed paraffin embedded tissues. We are also pursuing genomic predictors of recurrence in the brain as brain metastases from NSCLC is a major cause of morbidity and mortality. We are actively studying distinctive molecular changes associated with lung cancer in lifelong never smokers. Finally, our group is interested in exploring novel agents in the treatment of advanced NSCLC.
Clinical interests
Esophageal, thoracic and lung cancer
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Collaborations and top research areas from the last five years
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Accelerating discovery of cancer causes for prevention in the era of rising early-onset cancers
Shi, M., Patti, G. J., Gunter, M. J., Govindan, R., Lansdorp-Vogelaar, I., Wang, T., Townsend, J. P., Colditz, G. A., Belkaid, Y. & Cao, Y., Apr 16 2026, In: Cell. 189, 8, p. 2232-2253 22 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Emerging options and future strategies in immunotherapy for advanced lung squamous-cell carcinoma
Wang, Y., Rosell, R., Hirsch, F. R., Lu, S., Govindan, R., Park, K., Peters, S. & Zhang, J. J., Mar 2026, In: Annals of Oncology. 37, 3, p. 289-313 25 p.Research output: Contribution to journal › Review article › peer-review
Open Access5 Link opens in a new tab Scopus citations -
Evaluating the safety and efficacy of chemotherapy in patients with relapsed small cell lung cancer combined with allopurinol and MycoPhenolate (CLAMP)
Knapp, B., Waqar, S. N., Ward, J. P., Herzog, B. H., Vellequette, G., Cotton, A., Turlington, D., Plonsky, M., Wu, N., Mann, J., Rohatgi, A., Govindan, R., Devarakonda, S. & Morgensztern, D., May 2026, In: Lung Cancer. 215, 109382.Research output: Contribution to journal › Article › peer-review
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Fast Real-Time Assessment of Combination Therapies in Immuno-ONcology in patients with advanced non-small-cell lung cancer (FRACTION-Lung)
He, K., Forde, P. M., Govindan, R., Santoro, A., Gettinger, S., Borghaei, H., Spira, A., Chu, Q., Zinner, R., Schoenfeld, A. J., Camidge, D. R., Spigel, D. R., Gurpide, A., Juergens, R. A., Laurie, S. A., Cerra, M., Spires, T., Greenawalt, D. M., Rapoport, I. & Gainor, J. F., Mar 2026, In: ESMO Open. 11, 3, 106078.Research output: Contribution to journal › Article › peer-review
Open Access -
Germline alterations in patients with lung cancer
Govindan, R., Navo, K., Huang, M., Liu, J., Chao, C., Zong, X., Sankararaman, S., Bolton, K. & Cao, Y., May 2026, In: Annals of Oncology. 37, 5, p. 701-711 11 p.Research output: Contribution to journal › Article › peer-review
1 Link opens in a new tab Scopus citations