Research output per year
Research output per year
Personal profile
Research interests
Our group is interested in developing predictive and prognostic biomarkers in patients with non-small cell lung cancer(NSCLC). We have identified a 64 gene signature that accurately predicts the outcomes of patients with resected early stage NSCLC. We are in the process of developing a q RT PCR assay that could be performed in formalin fixed paraffin embedded tissues. We are also pursuing genomic predictors of recurrence in the brain as brain metastases from NSCLC is a major cause of morbidity and mortality. We are actively studying distinctive molecular changes associated with lung cancer in lifelong never smokers. Finally, our group is interested in exploring novel agents in the treatment of advanced NSCLC.
Clinical interests
Esophageal, thoracic and lung cancer
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Collaborations and top research areas from the last five years
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Author Correction: Pan-cancer analysis of whole genomes (Nature, (2020), 578, 7793, (82-93), 10.1038/s41586-020-1969-6)
The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium, Feb 16 2023, In: Nature. 614, 7948, p. E39Research output: Contribution to journal › Comment/debate
Open Access1 Scopus citations -
Clinician Perspectives on Barriers and Enablers to Implementing an Inpatient Oncology Early Warning System: A Mixed-Methods Study
Lyons, P. G., Chen, V., Sekhar, T. C., McEvoy, C. A., Kollef, M. H., Govindan, R., Westervelt, P., Vranas, K. C., Maddox, T. M., Geng, E. H., Payne, P. R. O. & Politi, M. C., Jan 1 2023, In: JCO Clinical Cancer Informatics. 7, p. e2200104Research output: Contribution to journal › Article › peer-review
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Clonal Hematopoiesis and Risk of Incident Lung Cancer
Tian, R., Wiley, B., Liu, J., Zong, X., Truong, B., Zhao, S., Uddin, M. M., Niroula, A., Miller, C. A., Mukherjee, S., Heiden, B. T., Luo, J., Puri, V., Kozower, B. D., Walter, M. J., Ding, L., Link, D. C., Amos, C. I., Ebert, B. L., Govindan, R., & 3 others, Mar 1 2023, In: Journal of Clinical Oncology. 41, 7, p. 1423-1433 11 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Integrated analysis of genomic and transcriptomic data for the discovery of splice-associated variants in cancer
Cotto, K. C., Feng, Y. Y., Ramu, A., Richters, M., Freshour, S. L., Skidmore, Z. L., Xia, H., McMichael, J. F., Kunisaki, J., Campbell, K. M., Chen, T. H. P., Rozycki, E. B., Adkins, D., Devarakonda, S., Sankararaman, S., Lin, Y., Chapman, W. C., Maher, C. A., Arora, V., Dunn, G. P., & 4 others, Dec 2023, In: Nature communications. 14, 1, 1589.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Management of infusion-related reactions (IRRs) in patients receiving amivantamab in the CHRYSALIS study
Park, K., Sabari, J. K., Haura, E. B., Shu, C. A., Spira, A., Salgia, R., Reckamp, K. L., Sanborn, R. E., Govindan, R., Bauml, J. M., Curtin, J. C., Xie, J., Roshak, A., Lorenzini, P., Millington, D., Thayu, M., Knoblauch, R. E. & Cho, B. C., Apr 2023, In: Lung Cancer. 178, p. 166-171 6 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations