• 25692 Citations
1992 …2020

Research output per year

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Personal profile

Research interests

Our group is interested in developing predictive and prognostic biomarkers in patients with non-small cell lung cancer(NSCLC). We have identified a 64 gene signature that accurately predicts the outcomes of patients with resected early stage NSCLC. We are in the process of developing a q RT PCR assay that could be performed in formalin fixed paraffin embedded tissues. We are also pursuing genomic predictors of recurrence in the brain as brain metastases from NSCLC is a major cause of morbidity and mortality. We are actively studying distinctive molecular changes associated with lung cancer in lifelong never smokers. Finally, our group is interested in exploring novel agents in the treatment of advanced NSCLC.

Areas of Clinical Interest

Esophageal, thoracic and lung cancer

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Research Output

Open Access
  • 2 Scopus citations

    Long non-coding RNA LCAL62 / LINC00261 is associated with lung adenocarcinoma prognosis

    Dang, H. X., White, N. M., Rozycki, E. B., Felsheim, B. M., Watson, M. A., Govindan, R., Luo, J. & Maher, C. A., Mar 2020, In : Heliyon. 6, 3, e03521.

    Research output: Contribution to journalArticle

    Open Access
  • 2 Scopus citations

    New Approaches to SCLC Therapy: From the Laboratory to the Clinic

    Poirier, J. T., George, J., Owonikoko, T. K., Berns, A., Brambilla, E., Byers, L. A., Carbone, D., Chen, H. J., Christensen, C. L., Dive, C., Farago, A. F., Govindan, R., Hann, C., Hellmann, M. D., Horn, L., Johnson, J. E., Ju, Y. S., Kang, S., Krasnow, M., Lee, J. & 27 others, Lee, S. H., Lehman, J., Lok, B., Lovly, C., MacPherson, D., McFadden, D., Minna, J., Oser, M., Park, K., Park, K. S., Pommier, Y., Quaranta, V., Ready, N., Sage, J., Scagliotti, G., Sos, M. L., Sutherland, K. D., Travis, W. D., Vakoc, C. R., Wait, S. J., Wistuba, I., Wong, K. K., Zhang, H., Daigneault, J., Wiens, J., Rudin, C. M. & Oliver, T. G., Apr 2020, In : Journal of Thoracic Oncology. 15, 4, p. 520-540 21 p.

    Research output: Contribution to journalReview article

  • 5 Scopus citations

    Pan-cancer analysis of whole genomes

    The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium, Feb 6 2020, In : Nature. 578, 7793, p. 82-93 12 p.

    Research output: Contribution to journalArticle

    Open Access
  • 109 Scopus citations

    Pooled overall survival and safety data from the pivotal phase II studies (NP28673 and NP28761) of alectinib in ALK-positive non-small-cell lung cancer

    Ou, S. H. I., Gadgeel, S. M., Barlesi, F., Yang, J. C. H., De Petris, L., Kim, D. W., Govindan, R., Dingemans, A. M., Crino, L., Léna, H., Popat, S., Ahn, J. S., Dansin, E., Mitry, E., Müller, B., Bordogna, W., Balas, B., Morcos, P. N. & Shaw, A. T., Jan 2020, In : Lung Cancer. 139, p. 22-27 6 p.

    Research output: Contribution to journalArticle

  • 2 Scopus citations