Research output per year
Research output per year
- 50 - 100 out of 167 results
Search results
-
2013
Genomic impact of transient low-dose decitabine treatment on primary AMLcells
Klco, J. M., Spencer, D. H., Lamprecht, T. L., Sarkaria, S. M., Wylie, T., Magrini, V., Hundal, J., Walker, J., Varghese, N., Erdmann-Gilmore, P., Lichti, C. F., Meyer, M. R., Townsend, R. R., Wilson, R. K., Mardis, E. R. & Ley, T. J., Feb 28 2013, In: Blood. 121, 9, p. 1633-1643 11 p.Research output: Contribution to journal › Article › peer-review
Open Access102 Scopus citations -
Quantitative Label-Free Proteomics for Discovery of Biomarkers in Cerebrospinal Fluid: Assessment of Technical and Inter-Individual Variation
Perrin, R. J., Payton, J. E., Malone, J. P., Gilmore, P., Davis, A. E., Xiong, C., Fagan, A. M., Townsend, R. R. & Holtzman, D. M., May 20 2013, In: PloS one. 8, 5, e64314.Research output: Contribution to journal › Article › peer-review
Open Access29 Scopus citations -
Single Point Mutations Result in the Miss-Sorting of Glut4 to a Novel Membrane Compartment Associated with Stress Granule Proteins
Song, X. M., Lichti, C. F., Townsend, R. R. & Mueckler, M., Jul 16 2013, In: PloS one. 8, 7, e68516.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
2012
Alterations in protein regulators of neurodevelopment in the cerebrospinal fluid of infants with posthemorrhagic hydrocephalus of prematurity
Morales, D. M., Townsend, R. R., Malone, J. P., Ewersmann, C. A., Macy, E. M., Inder, T. E. & Limbrick, D. D., Jun 2012, In: Molecular and Cellular Proteomics. 11, 6Research output: Contribution to journal › Article › peer-review
Open Access30 Scopus citations -
A neurosteroid analogue photolabeling reagent labels the colchicine-binding site on tubulin: A mass spectrometric analysis
Chen, Z. W., Chen, L. H., Akentieva, N., Lichti, C. F., Darbandi, R., Hastings, R., Covey, D. F., Reichert, D. E., Townsend, R. R. & Evers, A. S., Feb 2012, In: Electrophoresis. 33, 4, p. 666-674 9 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Deep amino acid sequencing of native brain GABAA receptors using high-resolution mass spectrometry
Chen, Z. W., Fuchs, K., Sieghart, W., Townsend, R. R. & Evers, A. S., Jan 2012, In: Molecular and Cellular Proteomics. 11, 1Research output: Contribution to journal › Article › peer-review
Open Access34 Scopus citations -
Identification of potential mediators of retinotopic mapping: A comparative proteomic analysis of optic nerve from WT and Phr1 retinal knockout mice
Lee, A. R., Lamb, R. R., Chang, J. H., Erdmann-Gilmore, P., Lichti, C. F., Rohrs, H. W., Malone, J. P., Wairkar, Y. P., Diantonio, A., Townsend, R. R. & Culican, S. M., Nov 2 2012, In: Journal of Proteome Research. 11, 11, p. 5515-5526 12 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Mass spectrometry-based identification of native cardiac Nav1.5 channel α subunit phosphorylation sites
Marionneau, C., Lichti, C. F., Lindenbaum, P., Charpentier, F., Nerbonne, J. M., Townsend, R. R. & Mérot, J., Dec 7 2012, In: Journal of Proteome Research. 11, 12, p. 5994-6007 14 p.Research output: Contribution to journal › Article › peer-review
41 Scopus citations -
Multiplex proteomics analysis of gender-associated proteins in Brugia malayi
Jiang, D., Malone, J., Townsend, R., Weil, G. J. & Li, B., Aug 2012, In: International Journal for Parasitology. 42, 9, p. 841-850 10 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Neurosteroid analog photolabeling of a site in the third transmembrane domain of the β3 subunit of the GABAA receptor
Chen, Z. W., Manion, B., Townsend, R. R., Reichert, D. E., Covey, D. F., Steinbach, J. H., Sieghart, W., Fuchs, K. & Evers, A. S., Sep 2012, In: Molecular pharmacology. 82, 3, p. 408-419 12 p.Research output: Contribution to journal › Article › peer-review
54 Scopus citations -
The role of molecular chaperonins in warm ischemia and reperfusion injury in the steatotic liver: A proteomic study
Tiriveedhi, V., Conzen, K. D., Liaw-Conlin, J., Upadhya, G., Malone, J., Townsend, R. R., Kerns, R., Jia, J., Csontos, K., Ramachandran, S., Mohanakumar, T., Anderson, C. D. & Chapman, W. C., 2012, In: BMC Biochemistry. 13, 1, 17.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
The sodium channel accessory subunit Navβ1 regulates neuronal excitability through modulation of repolarizing Voltage-gated K+ channels
Marionneau, C., Carrasquillo, Y., Norris, A. J., Reid Townsend, R., Isom, L. L., Link, A. J. & Nerbonne, J. M., Apr 25 2012, In: Journal of Neuroscience. 32, 17, p. 5716-5727 12 p.Research output: Contribution to journal › Article › peer-review
Open Access66 Scopus citations -
2011
A bioinformatics approach for biomarker identification in radiation-induced lung inflammation from limited proteomics data
Oh, J. H., Craft, J. M., Townsend, R., Deasy, J. O., Bradley, J. D. & El Naqa, I., Mar 4 2011, In: Journal of Proteome Research. 10, 3, p. 1406-1415 10 p.Research output: Contribution to journal › Article › peer-review
39 Scopus citations -
Cross-species comparison of orthologous gene expression in human bladder cancer and carcinogen-induced rodent models
Lu, Y., Liu, P., Wen, W., Grubbs, C. J., Townsend, R. R., Malone, J. P., Lubet, R. A. & You, M., 2011, In: American Journal of Translational Research. 3, 1, p. 8-27 20 p.Research output: Contribution to journal › Article › peer-review
51 Scopus citations -
Efficacy of the EGFr inhibitor Iressa on development of chemically-induced urinary bladder cancers: Dose dependency and modulation of biomarkers
Lubet, R. A., Lu, Y., Bode, A. M., You, M., Verney, Z. M., Steele, V. E., Townsend, R., Juliana, M. M. & Grubbs, C. J., May 2011, In: Oncology reports. 25, 5, p. 1389-1397 9 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Identification and Validation of Novel Cerebrospinal Fluid Biomarkers for Staging Early Alzheimer's Disease
Perrin, R. J., Craig-Schapiro, R., Malone, J. P., Shah, A. R., Gilmore, P., Davis, A. E., Roe, C. M., Peskind, E. R., Li, G., Galasko, D. R., Clark, C. M., Quinn, J. F., Kaye, J. A., Morris, J. C., Holtzman, D. M., Townsend, R. & Fagan, A. M., 2011, In: PloS one. 6, 1, e16032.Research output: Contribution to journal › Article › peer-review
Open Access139 Scopus citations -
Identification of CaMKII phosphorylation sites in connexin43 by high-resolution mass spectrometry
Huang, R. Y. C., Laing, J. G., Kanter, E. M., Berthoud, V. M., Bao, M., Rohrs, H. W., Townsend, R. R. & Yamada, K. A., Mar 4 2011, In: Journal of Proteome Research. 10, 3, p. 1098-1109 12 p.Research output: Contribution to journal › Article › peer-review
44 Scopus citations -
Identification of FUSE-binding protein 1 as a regulatory mRNA-binding protein that represses nucleophosmin translation
Olanich, M. E., Moss, B. L., Piwnica-Worms, D., Townsend, R. R. & Weber, J. D., Jan 6 2011, In: Oncogene. 30, 1, p. 77-86 10 p.Research output: Contribution to journal › Article › peer-review
Open Access33 Scopus citations -
Identification of in vitro autophosphorylation sites and effects of phosphorylation on the arabidopsis CRINKLY4 (ACR4) receptor-like kinase intracellular domain: Insights into conformation, oligomerization, and activity
Meyer, M. R., Lichti, C. F., Townsend, R. R. & Rao, A. G., Mar 29 2011, In: Biochemistry. 50, 12, p. 2170-2186 17 p.Research output: Contribution to journal › Article › peer-review
21 Scopus citations -
Inhibition of lens photodamage by UV-absorbing contact lenses
Andley, U. P., Malone, J. P. & Reid Townsend, R., Oct 2011, In: Investigative Ophthalmology and Visual Science. 52, 11, p. 8330-8341 12 p.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
Proteomic analysis highlights the molecular complexities of native Kv4 channel macromolecular complexes
Marionneau, C., Townsend, R. R. & Nerbonne, J. M., Apr 2011, In: Seminars in Cell and Developmental Biology. 22, 2, p. 145-152 8 p.Research output: Contribution to journal › Review article › peer-review
18 Scopus citations -
Residual Cx45 and its relationship to Cx43 in Murine ventricular myocardium
Bao, M., Kanter, E. M., Huang, R. Y. C., Maxeiner, S., Frank, M., Zhang, Y., Schuessler, R. B., Smith, T. W., Townsend, R. R., Rohrs, H. W., Berthoud, V. M., Willecke, K., Laing, J. G. & Yamada, K. A., 2011, In: Channels. 5, 6, p. 489-499 11 p.Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
RNA helicase DDX5 is a p53-independent target of ARF that participates in ribosome biogenesis
Saporita, A. J., Chang, H. C., Winkeler, C. L., Apicelli, A. J., Kladney, R. D., Wang, J., Townsend, R. R., Michel, L. S. & Weber, J. D., Nov 1 2011, In: Cancer research. 71, 21, p. 6708-6717 10 p.Research output: Contribution to journal › Article › peer-review
Open Access42 Scopus citations -
2010
Airway proteins involved in bacterial clearance susceptible to cathepsin G proteolysis
Farberman, M. M., Akers, K. T., Malone, J. P., Erdman-Gilmore, P., Townsend, R. R. & Ferkol, T., Feb 2010, In: European Respiratory Journal. 35, 2, p. 410-417 8 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
DNMT3A mutations in acute myeloid leukemia
Ley, T. J., Ding, L., Walter, M. J., McLellan, M. D., Lamprecht, T., Larson, D. E., Kandoth, C., Payton, J. E., Baty, J., Welch, J., Harris, C. C., Lichti, C. F., Townsend, R. R., Fulton, R. S., Dooling, D. J., Koboldt, D. C., Schmidt, H., Zhang, Q., Osborne, J. R., Lin, L. & 28 others, , Dec 16 2010, In: New England Journal of Medicine. 363, 25, p. 2424-2433 10 p.Research output: Contribution to journal › Article › peer-review
1452 Scopus citations -
Hsp 70/Hsp 90 organizing protein as a nitrosylation target in cystic fibrosis therapy
Marozkina, N. V., Yemen, S., Borowitz, M., Liu, L., Plapp, M., Sun, F., Islam, R., Erdmann-Gilmore, P., Townsend, R. R., Lichti, C. F., Mantri, S., Clapp, P. W., Randell, S. H., Gaston, B. & Zaman, K., Jun 22 2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 25, p. 11393-11398 6 p.Research output: Contribution to journal › Article › peer-review
Open Access59 Scopus citations -
Phosphorylation of immunity-related GTPases by a toxoplasma gondii-secreted kinase promotes macrophage survival and virulence
Fentress, S. J., Behnke, M. S., Dunay, I. R., Mashayekhi, M., Rommereim, L. M., Fox, B. A., Bzik, D. J., Taylor, G. A., Turk, B. E., Lichti, C. F., Townsend, R. R., Qiu, W., Hui, R., Beatty, W. L. & Sibley, L. D., Dec 16 2010, In: Cell Host and Microbe. 8, 6, p. 484-495 12 p.Research output: Contribution to journal › Article › peer-review
Open Access226 Scopus citations -
Revealing novel telomere proteins using in vivo cross-linking, tandem affinity purification, and label-free quantitative LC-FTICR-MS
Nittis, T., Guittat, L., LeDuc, R. D., Dao, B., Duxin, J. P., Rohrs, H., Townsend, R. R. & Stewart, S. A., Jun 2010, In: Molecular and Cellular Proteomics. 9, 6, p. 1144-1156 13 p.Research output: Contribution to journal › Article › peer-review
Open Access44 Scopus citations -
Serum markers may distinguish biliary atresia from other forms of neonatal cholestasis
Wang, H., Malone, J. P., Gilmore, P. E., Davis, A. E., Magee, J. C., Townsend, R. R. & Heuckeroth, R. O., Apr 2010, In: Journal of pediatric gastroenterology and nutrition. 50, 4, p. 411-416 6 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
The haemophilus influenzae HMW1c protein is a glycosyltransferase that transfers hexose residues to asparagine sites in the HMW1 adhesin
Grass, S., Lichti, C. F., Townsend, R. R., Gross, J. & St. Geme, J. W., May 2010, In: PLoS pathogens. 6, 5, p. 1-9 9 p.Research output: Contribution to journal › Article › peer-review
Open Access81 Scopus citations -
YKL-40: A novel prognostic fluid biomarker for preclinical Alzheimer's disease
Craig-Schapiro, R., Perrin, R. J., Roe, C. M., Xiong, C., Carter, D., Cairns, N. J., Mintun, M. A., Peskind, E. R., Li, G., Galasko, D. R., Clark, C. M., Quinn, J. F., D'Angelo, G., Malone, J. P., Townsend, R. R., Morris, J. C., Fagan, A. M. & Holtzman, D. M., Nov 15 2010, In: Biological Psychiatry. 68, 10, p. 903-912 10 p.Research output: Contribution to journal › Article › peer-review
294 Scopus citations -
2009
Erratum: Mechanism of small heat shock protein function in vivo. A knock-in mouse model demonstrates that the R49C mutation in αA-crystallin enhances protein insolubility and cell death (The Journal of Biological Chemistry (2008) vol. 283 (5801-5814) 10.1074/ A708704200)
Xi, J. H., Bai, F., Gross, J., Townsend, R. R., Menko, A. S. & Andley, U. P., Dec 18 2009, In: Journal of Biological Chemistry. 284, 51, p. 35996 1 p.Research output: Contribution to journal › Comment/debate
Open Access -
Proteomic analyses of native brain KV4.2 channel complexes
Marionneau, C., LeDuc, R. D., Rohrs, H. W., Link, A. J., Townsend, R. R. & Nerbonne, J. M., 2009, In: Channels. 3, 4Research output: Contribution to journal › Article › peer-review
29 Scopus citations -
Proteomic analysis of anoxia tolerance in the developing zebrafish embryo
Mendelsohn, B. A., Malone, J. P., Townsend, R. R. & Gitlin, J. D., Mar 2009, In: Comparative Biochemistry and Physiology - Part D: Genomics and Proteomics. 4, 1, p. 21-31 11 p.Research output: Contribution to journal › Article › peer-review
32 Scopus citations -
Proteomic comparison of Entamoeba histolytica and Entamoeba dispar and the role of E. histolytica alcohol dehydrogenase 3 in virulence
Davis, P. H., Chen, M., Zhang, X., Clark, C. G., Townsend, R. R. & Stanley, S. L., 2009, In: PLoS neglected tropical diseases. 3, 4, e415.Research output: Contribution to journal › Article › peer-review
Open Access27 Scopus citations -
The asialoglycoprotein receptor regulates levels of plasma glycoproteins terminating with sialic acid α2,6-galactose
Steirer, L. M., Park, E. I., Townsend, R. R. & Baenzinger, J. U., Feb 6 2009, In: Journal of Biological Chemistry. 284, 6, p. 3777-3783 7 p.Research output: Contribution to journal › Article › peer-review
Open Access69 Scopus citations -
Urinary cysteinyl leukotriene E4 significantly increases during pain in children and adults with sickle cell disease
Field, J. J., Strunk, R. C., Knight-Perry, J. E., Blinder, M. A., Townsend, R. R. & DeBaun, M. R., Apr 2009, In: American journal of hematology. 84, 4, p. 231-233 3 p.Research output: Contribution to journal › Article › peer-review
24 Scopus citations -
2008
A unified sample preparation protocol for proteomic and genomic profiling of cervical swabs to identify biomarkers for cervical cancer screening
Rader, J. S., Malone, J. P., Gross, J., Gilmore, P., Brooks, R. A., Nguyen, L., Crimmins, D. L., Feng, S., Wright, J. D., Taylor, N., Zighelboim, I., Funk, M. C., Huettner, P. C., Ledenson, J. H., Gius, D. & Townsend, R. R., 2008, In: Proteomics - Clinical Applications. 2, 12, p. 1658-1669 12 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
Carboxypeptidase E mediates palmitate-induced β-cell ER stress and apoptosis
Jeffrey, K. D., Alejandro, E. U., Luciani, D. S., Kalynyak, T. B., Hu, X., Li, H., Lin, Y., Townsend, R. R., Polonsky, K. S. & Johnson, J. D., Jun 17 2008, In: Proceedings of the National Academy of Sciences of the United States of America. 105, 24, p. 8452-8457 6 p.Research output: Contribution to journal › Article › peer-review
Open Access115 Scopus citations -
Mechanism of small heat shock protein function in vivo: A knock-in mouse model demonstrates that the R49C mutation in αA-crystallin enhances protein insolubility and cell death
Xi, J. H., Bai, F., Gross, J., Townsend, R. R., Menko, A. S. & Andley, U. P., Feb 29 2008, In: Journal of Biological Chemistry. 283, 9, p. 5801-5814 14 p.Research output: Contribution to journal › Article › peer-review
Open Access51 Scopus citations -
Nucleophosmin serves as a rate-limiting nuclear export chaperone for the mammalian ribosome
Maggi, L. B., Kuchenruether, M., Dadey, D. Y. A., Schwope, R. M., Grisendi, S., Townsend, R. R., Pandolfi, P. P. & Weber, J. D., Dec 2008, In: Molecular and cellular biology. 28, 23, p. 7050-7065 16 p.Research output: Contribution to journal › Article › peer-review
Open Access157 Scopus citations -
The Haemophilus influenzae HMW1 adhesin is a glycoprotein with an unusual N-linked carbohydrate modification
Gross, J., Grass, S., Davis, A. E., Gilmore-Erdmann, P., Townsend, R. R. & St. Geme, J. W., Sep 19 2008, In: Journal of Biological Chemistry. 283, 38, p. 26010-26015 6 p.Research output: Contribution to journal › Article › peer-review
Open Access83 Scopus citations -
2007
Identification and validation of novel CSF biomarkers for early stages of Alzheimer's disease
Hu, Y., Hosseini, A., Kauwe, J. S. K., Gross, J., Cairns, N. J., Goate, A. M., Fagan, A. M., Townsend, R. R. & Holtzman, D. M., Nov 2007, In: Proteomics - Clinical Applications. 1, 11, p. 1373-1384 12 p.Research output: Contribution to journal › Article › peer-review
49 Scopus citations -
Identification of protein phosphorylation sites within Ser/Thr-rich cluster domains using site-directed mutagenesis and hybrid linear quadrupole ion trap Fourier transform ion cyclotron resonance mass spectrometry
King, J. B., Gross, J., Lovly, C. M., Piwnica-Worms, H. & Townsend, R. R., 2007, In: Rapid Communications in Mass Spectrometry. 21, 21, p. 3443-3451 9 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
Nampt/PBEF/Visfatin Regulates Insulin Secretion in β Cells as a Systemic NAD Biosynthetic Enzyme
Revollo, J. R., Körner, A., Mills, K. F., Satoh, A., Wang, T., Garten, A., Dasgupta, B., Sasaki, Y., Wolberger, C., Townsend, R. R., Milbrandt, J., Kiess, W. & Imai, S. I., Nov 7 2007, In: Cell metabolism. 6, 5, p. 363-375 13 p.Research output: Contribution to journal › Article › peer-review
Open Access678 Scopus citations -
Respiratory Uncoupling in Skeletal Muscle Delays Death and Diminishes Age-Related Disease
Gates, A. C., Bernal-Mizrachi, C., Chinault, S. L., Feng, C., Schneider, J. G., Coleman, T., Malone, J. P., Townsend, R. R., Chakravarthy, M. V. & Semenkovich, C. F., Dec 5 2007, In: Cell metabolism. 6, 6, p. 497-505 9 p.Research output: Contribution to journal › Article › peer-review
Open Access84 Scopus citations -
The murine plasma protein response to polymicrobial intra-abdominal sepsis
McDunn, J. E., Townsend, R. R. & Cobb, J. P., Apr 1 2007, In: Proteomics - Clinical Applications. 1, 4, p. 373-386 14 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Two Cys residues essential for von Willebrand factor multimer assembly in the Golgi
Purvis, A. R., Gross, J., Dang, L. T., Huang, R. H., Kapadia, M., Townsend, R. R. & Sadler, J. E., Oct 2 2007, In: Proceedings of the National Academy of Sciences of the United States of America. 104, 40, p. 15647-15652 6 p.Research output: Contribution to journal › Article › peer-review
54 Scopus citations -
2006
Accurate mass-driven analysis for the characterization of protein phosphorylation. Study of the human Chk2 protein kinase
King, J. B., Gross, J., Lovly, C. M., Rohrs, H., Piwnica-Worms, H. & Townsend, R. R., Apr 1 2006, In: Analytical Chemistry. 78, 7, p. 2171-2181 11 p.Research output: Contribution to journal › Article › peer-review
34 Scopus citations -
Comparative proteomic analysis of two Entamoeba histolytica strains with different virulence phenotypes identifies peroxiredoxin as an important component of amoebic virulence
Davis, P. H., Zhang, X., Guo, J., Townsend, R. R. & Stanley, S. L., Sep 2006, In: Molecular Microbiology. 61, 6, p. 1523-1532 10 p.Research output: Contribution to journal › Article › peer-review
Open Access88 Scopus citations