R Reid Townsend

Research output

Research output per year 1978 1996 2005 2006 2007 2009 2010 2011 2012 2013 2014 2016 2017 2023

• 165 Article
• 5 Review article
• 2 Comment/debate
• 1 Paper
• 2 More
  • 1 Conference article
  • 1 Letter

Research output per year

Research output per year

Search results

• Targeted peptide measurements in biology and medicine: Best practices for mass spectrometry-based assay development using a fit-for-purpose approach

  Carr, S. A., Abbatiello, S. E., Ackermann, B. L., Borchers, C., Domon, B., Deutsch, E. W., Grant, R. P., Hoofnagle, A. N., Hüttenhain, R., Koomen, J. M., Liebler, D. C., Liu, T., MacLean, B., Mani, D. R., Mansfield, E., Neubert, H., Paulovich, A. G., Reiter, L., Vitek, O., Aebersold, R., & 25 othersAnderson, L., Bethem, R., Blonder, J., Boja, E., Botelho, J., Boyne, M., Bradshaw, R. A., Burlingame, A. L., Chan, D., Keshishian, H., Kuhn, E., Kinsinger, C., Lee, J. S. H., Lee, S. W., Moritz, R., Oses-Prieto, J., Rifai, N., Ritchie, J., Rodriguez, H., Srinivas, P. R., Townsend, R. R., Van Eyk, J., Whiteley, G., Wiita, A. & Weintraub, S., Mar 2014, In: Molecular and Cellular Proteomics. 13, 3, p. 907-917 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Practice Guidelines 100%
  • Mass Spectrometry 96%
  • Medicine 78%
  • Peptides 68%
  • Peptide 61%
  414 Scopus citations

• The asialoglycoprotein receptor regulates levels of plasma glycoproteins terminating with sialic acid α2,6-galactose

  Steirer, L. M., Park, E. I., Townsend, R. R. & Baenzinger, J. U., Feb 6 2009, In: Journal of Biological Chemistry. 284, 6, p. 3777-3783 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Asialoglycoprotein Receptor 100%
  • N-Acetylneuraminic Acid 77%
  • Sialic Acid 74%
  • Galactose 73%
  • Glycoprotein 61%
  74 Scopus citations

• The Haemophilus influenzae HMW1 adhesin is a glycoprotein with an unusual N-linked carbohydrate modification

  Gross, J., Grass, S., Davis, A. E., Gilmore-Erdmann, P., Townsend, R. R. & St. Geme, J. W., Sep 19 2008, In: Journal of Biological Chemistry. 283, 38, p. 26010-26015 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • bacteria HMW1 protein 100%
  • Haemophilus influenzae 53%
  • Glycosylation 48%
  • Glycoprotein 43%
  • Carbohydrates 41%
  84 Scopus citations

• The haemophilus influenzae HMW1c protein is a glycosyltransferase that transfers hexose residues to asparagine sites in the HMW1 adhesin

  Grass, S., Lichti, C. F., Townsend, R. R., Gross, J. & St. Geme, J. W., May 2010, In: PLoS pathogens. 6, 5, p. 1-9 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • bacteria HMW1 protein 100%
  • Glycosyltransferases 63%
  • Hexoses 62%
  • adhesins 61%
  • Asparagine 58%
  86 Scopus citations

• The major subunit of the rat asialoglycoprotein receptor can function alone as a receptor

  Braiterman, L. T., Chance, S. C., Porter, W. R., Lee, Y. C., Townsend, R. R. & Hubbard, A. L., 1989, In: Journal of Biological Chemistry. 264, 3, p. 1682-1688 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Asialoglycoprotein Receptor 100%
  • asialoorosomucoid 51%
  • Ligand 29%
  • Ligands 21%
  • Lectin 17%
  41 Scopus citations

• The murine plasma protein response to polymicrobial intra-abdominal sepsis

  McDunn, J. E., Townsend, R. R. & Cobb, J. P., Apr 1 2007, In: Proteomics - Clinical Applications. 1, 4, p. 373-386 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Blood Proteins 100%
  • Sepsis 90%
  • Plasma 69%
  • Molecular Marker 48%
  • Protein 46%
  10 Scopus citations

• The N-linked oligosaccharides of the β-subunit of rabbit gastric H,K- ATPase: Site localization and identification of novel structures

  Tyagarajan, K., Lipniunas, P. H., Townsend, R. R. & Forte, J. G., Aug 19 1997, In: Biochemistry. 36, 33, p. 10200-10212 13 p.

  Research output: Contribution to journal › Article › peer-review

  • lactosamine 100%
  • Lactosamine 95%
  • H(+)-K(+)-Exchanging ATPase 94%
  • Oligosaccharides 64%
  • Oligosaccharide 54%
  34 Scopus citations

• The Notch Intracellular Domain Has an RBPj-Independent Role during Mouse Hair Follicular Development

  Turkoz, M., Townsend, R. R. & Kopan, R., 2016, In: Journal of Investigative Dermatology. 136, 6, p. 1106-1115 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Amyloid Precursor Protein Secretases 100%
  • Hair 80%
  • Carrier Proteins 68%
  • Organogenesis 65%
  • thymic stromal lymphopoietin 40%
  11 Scopus citations

• The R882H DNMT3A Mutation Associated with AML Dominantly Inhibits Wild-Type DNMT3A by Blocking Its Ability to Form Active Tetramers

  Russler-Germain, D. A., Spencer, D. H., Young, M. A., Lamprecht, T. L., Miller, C. A., Fulton, R., Meyer, M. R., Erdmann-Gilmore, P., Townsend, R. R., Wilson, R. K. & Ley, T. J., Apr 14 2014, In: Cancer Cell. 25, 4, p. 442-454 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Methyltransferases 100%
  • Acute Myeloid Leukemia 85%
  • Myeloid Cells 61%
  • Mutation 50%
  • Enzymes 32%
  307 Scopus citations

• The role of molecular chaperonins in warm ischemia and reperfusion injury in the steatotic liver: A proteomic study

  Tiriveedhi, V., Conzen, K. D., Liaw-Conlin, J., Upadhya, G., Malone, J., Townsend, R. R., Kerns, R., Jia, J., Csontos, K., Ramachandran, S., Mohanakumar, T., Anderson, C. D. & Chapman, W. C., 2012, In: BMC Biochemistry. 13, 1, 17.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Chaperonins 100%
  • Warm Ischemia 87%
  • Reperfusion Injury 65%
  • Proteomics 62%
  • Zucker Rats 36%
  6 Scopus citations

• The sodium channel accessory subunit Navβ1 regulates neuronal excitability through modulation of repolarizing Voltage-gated K⁺ channels

  Marionneau, C., Carrasquillo, Y., Norris, A. J., Reid Townsend, R., Isom, L. L., Link, A. J. & Nerbonne, J. M., Apr 25 2012, In: Journal of Neuroscience. 32, 17, p. 5716-5727 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Voltage-Gated Potassium Channels 100%
  • Sodium Channels 89%
  • Firearms 86%
  • Pyramidal Cells 79%
  • Proteomics 69%
  67 Scopus citations

• The β-subunit of the rabbit H,K-ATPase: A glycoprotein with all terminal lactosamine units capped with α-linked galactose residues

  Tyagarajan, K., Townsend, R. R. & Forte, J. G., Mar 12 1996, In: Biochemistry. 35, 10, p. 3238-3246 9 p.

  Research output: Contribution to journal › Article › peer-review

  • lactosamine 100%
  • Lactosamine 95%
  • Proton-Translocating ATPases 75%
  • Oligosaccharides 64%
  • Galactose 63%
  26 Scopus citations

• Topology and glycosylation of the gastric h.k-atpase

  Townsend, R. R., Tyagarajan, K. & Forte, J. G., Dec 1 1997, In: FASEB Journal. 11, 9, p. A1128

  Research output: Contribution to journal › Article › peer-review

  • lactosamine 100%
  • Proton-Translocating ATPases 75%
  • Lactosamine 71%
  • Oligosaccharides 64%
  • Glycosylation 59%

• Topology of membrane proteins in native membranes using matrix-assisted laser desorption ionization/mass spectrometry

  Tyagarajan, K., Forte, J. G. & Townsend, R. R., 1997, In: Techniques in Protein Chemistry. 8, C, p. 533-542 10 p.

  Research output: Contribution to journal › Article › peer-review

• Two Cys residues essential for von Willebrand factor multimer assembly in the Golgi

  Purvis, A. R., Gross, J., Dang, L. T., Huang, R. H., Kapadia, M., Townsend, R. R. & Sadler, J. E., Oct 2 2007, In: Proceedings of the National Academy of Sciences of the United States of America. 104, 40, p. 15647-15652 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • von Willebrand Factor 100%
  • Disulfides 36%
  • Ethylmaleimide 29%
  • Mutation 25%
  • Oxidoreductases 20%
  62 Scopus citations

• Type IV Pili Are a Critical Virulence Factor in Clinical Isolates of Paenibacillus thiaminolyticus

  Hehnly, C., Shi, A., Ssentongo, P., Zhang, L., Isaacs, A., Morton, S. U., Streck, N., Erdmann-Gilmore, P., Tolstoy, I., Reid Townsend, R., Limbrick, D. D., Paulson, J. N., Ericson, J. E., Galperin, M. Y., Schiff, S. J. & Broach, J. R., Dec 2022, In: mBio. 13, 6

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Paenibacillus 100%
  • Hydrocephalus 65%
  • Virulence Factors 64%
  • Interspersed Repetitive Sequences 26%
  • Clustered Regularly Interspaced Short Palindromic Repeats 14%

• Unique oligosaccharides of the gastric h,k-atpase

  Forte, J. G., Tyagarajan, K., Crothers, J. M., Appelmelk, B. J. & Townsend, R. R., Dec 1 1996, In: FASEB Journal. 10, 6, p. A1085

  Research output: Contribution to journal › Article › peer-review

  • Proton-Translocating ATPases 100%
  • Oligosaccharides 86%
  • Adenosine Triphosphatases 77%
  • Oligosaccharide 71%
  • Stomach 55%

• Urinary cysteinyl leukotriene E₄ significantly increases during pain in children and adults with sickle cell disease

  Field, J. J., Strunk, R. C., Knight-Perry, J. E., Blinder, M. A., Townsend, R. R. & DeBaun, M. R., Apr 2009, In: American journal of hematology. 84, 4, p. 231-233 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Leukotriene E4 100%
  • cysteinyl-leukotriene 97%
  • Sickle Cell Anemia 73%
  • Pain 38%
  • Creatinine 35%
  24 Scopus citations

• Use of protease proteomics to discover granzyme B substrates

  Bredemeyer, A. J., Townsend, R. R. & Ley, T. J., 2005, In: Immunologic Research. 32, 1-3, p. 143-153 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • Granzymes 100%
  • Proteomics 71%
  • Peptide Hydrolases 64%
  • Electrophoresis, Gel, Two-Dimensional 18%
  • Substrate Specificity 17%
  12 Scopus citations

• Use of proteomic methods to identify serum biomarkers associated with rat liver toxicity or hypertrophy

  Amacher, D. E., Adler, R., Herath, A. & Townsend, R. R., Oct 2005, In: Clinical chemistry. 51, 10, p. 1796-1803 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Proteomics 100%
  • Hypertrophy 99%
  • Biological Marker 98%
  • Biomarkers 70%
  • Liver 56%
  84 Scopus citations

• Using the cptac assay portal to identify and implement highly characterized targeted proteomics assays

  Whiteaker, J. R., Halusa, G. N., Hoofnagle, A. N., Sharma, V., MacLean, B., Yan, P., Wrobel, J. A., Kennedy, J., Mani, D. R., Zimmerman, L. J., Meyer, M. R., Mesri, M., Boja, E., Carr, S. A., Chan, D. W., Chen, X., Chen, J., Davies, S. R., Ellis, M. J. C., Fenyö, D., & 22 othersHiltke, T., Ketchum, K. A., Kinsinger, C., Kuhn, E., Liebler, D. C., Liu, T., Loss, M., Maccoss, M. J., Qian, W. J., Rivers, R., Rodland, K. D., Ruggles, K. V., Scott, M. G., Smith, R. D., Thomas, S., Townsend, R. R., Whiteley, G., Wu, C., Zhang, H., Zhang, Z., Rodriguez, H. & Paulovich, A. G., Feb 1 2016, In: Methods in Molecular Biology. 1410, p. 223-236 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Proteomics 100%
  • Mass Spectrometry 48%
  • Proteins 40%
  • National Cancer Institute (U.S.) 31%
  • Post Translational Protein Processing 28%
  25 Scopus citations

• Vascular respiratory uncoupling increases blood pressure and atherosclerosis

  Bernal-Mizrachi, C., Gates, A. C., Weng, S., Imamura, T., Knutsen, R. H., DeSantis, P., Coleman, T., Townsend, R. R., Muglia, L. J. & Semenkovich, C. F., May 26 2005, In: Nature. 435, 7041, p. 502-506 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Uncoupling Protein 1 100%
  • Atherosclerosis 94%
  • Blood Pressure 74%
  • Blood Vessels 68%
  • Vascular Diseases 68%
  148 Scopus citations

• Wavelet-based peak detection and a new charge inference procedure for MS/MS implemented in proteo wizard's msconvert

  French, W. R., Zimmerman, L. J., Schilling, B., Gibson, B. W., Miller, C. A., Townsend, R. R., Sherrod, S. D., Goodwin, C. R., McLean, J. A. & Tabb, D. L., Feb 6 2015, In: Journal of Proteome Research. 14, 2, p. 1299-1307 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Tandem Mass Spectrometry 100%
  • Software 60%
  • Workflow 43%
  • Quadrupole 38%
  • Proteomics 36%
  34 Scopus citations

• West Nile virus nonstructural protein NS1 inhibits complement activation by binding the regulatory protein factor H

  Kyung, M. C., Liszewski, M. K., Nybakken, G., Davis, A. E., Townsend, R. R., Fremont, D. H., Atkinson, J. P. & Diamond, M. S., Dec 12 2006, In: Proceedings of the National Academy of Sciences of the United States of America. 103, 50, p. 19111-19116 6 p.

  Research output: Contribution to journal › Article › peer-review

  • West Nile virus nonstructural protein 1 100%
  • Complement Factor H 64%
  • Complement Activation 54%
  • Carrier Proteins 40%
  • Complement Membrane Attack Complex 32%
  188 Scopus citations

• YKL-40: A novel prognostic fluid biomarker for preclinical Alzheimer's disease

  Craig-Schapiro, R., Perrin, R. J., Roe, C. M., Xiong, C., Carter, D., Cairns, N. J., Mintun, M. A., Peskind, E. R., Li, G., Galasko, D. R., Clark, C. M., Quinn, J. F., D'Angelo, G., Malone, J. P., Townsend, R. R., Morris, J. C., Fagan, A. M. & Holtzman, D. M., Nov 15 2010, In: Biological Psychiatry. 68, 10, p. 903-912 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Mental Status and Dementia Tests 100%
  • Alzheimer Disease 99%
  • Cerebrospinal Fluid 83%
  • Biomarkers 83%
  • Primary Spontaneous Pneumothorax 68%
  327 Scopus citations