• 12893 Citations
1978 …2019

Research output per year

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Personal profile

Research interests

Dr. Townsend’s primary research interest is the discovery and validation of biomakers in tissues and biological fluids using proteomics and metabolomics. His research program focuses on the development of robust sample preparation and separation methods and the application of advanced mass spectrometric technologies to clinical medicine. His laboratory has ongoing collaborative protein biomarker projects in cancer (pancreatic, breast, prostate and bladder) and Alzheimer’s disease using plasma, CSF, urine and formalin-fixed tissues. The laboratory is developing quantitative survey metabolomic methods for plasma and tissues, and targeted analysis of chemical classes of metabolites.

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Research Output

Diurnal Rhythms Spatially and Temporally Organize Autophagy

Ryzhikov, M., Ehlers, A., Steinberg, D., Xie, W., Oberlander, E., Brown, S., Gilmore, P. E., Townsend, R. R., Lane, W. S., Dolinay, T., Nakahira, K., Choi, A. M. K. & Haspel, J. A., Feb 12 2019, In : Cell Reports. 26, 7, p. 1880-1892.e6

Research output: Contribution to journalArticle

Open Access
  • 13 Scopus citations

    Interrogation of a live-attenuated enterotoxigenic Escherichia coli vaccine highlights features unique to wild-type infection

    Chakraborty, S., Randall, A., Vickers, T. J., Molina, D., Harro, C. D., DeNearing, B., Brubaker, J., Sack, D. A., Bourgeois, A. L., Felgner, P. L., Liang, X., Mani, S., Wenzel, H., Townsend, R. R., Gilmore, P. E., Darsley, M. J., Rasko, D. A. & Fleckenstein, J. M., Dec 1 2019, In : npj Vaccines. 4, 1, 37.

    Research output: Contribution to journalArticle

    Open Access
  • 2 Scopus citations

    Proteogenomic Analysis of Human Colon Cancer Reveals New Therapeutic Opportunities

    Clinical Proteomic Tumor Analysis Consortium, May 2 2019, In : Cell. 177, 4, p. 1035-1049.e19

    Research output: Contribution to journalArticle

    Open Access
  • 72 Scopus citations

    Proteomic analysis of synovial fluid identifies periostin as a biomarker for anterior cruciate ligament injury

    Brophy, R. H., Cai, L., Duan, X., Zhang, Q., Townsend, R. R., Nunley, R. M., Guilak, F. & Rai, M. F., Dec 2019, In : Osteoarthritis and Cartilage. 27, 12, p. 1778-1789 12 p.

    Research output: Contribution to journalArticle

  • 1 Scopus citations

    Regulated phosphosignaling associated with breast cancer subtypes and druggability

    Huang, K. L., Wu, Y., Primeau, T., Wang, Y. T., Gao, Y., McMichael, J. F., Scott, A. D., Cao, S., Wendl, M. C., Johnson, K. J., Ruggles, K., Held, J., Payne, S. H., Davies, S., Dar, A., Kinsinger, C. R., Mesri, M., Rodriguez, H., Ellis, M. J., Reid Townsend, R. & 6 others, Chen, F., Fenyö, D., Li, S., Liu, T., Carr, S. A. & Ding, L., 2019, In : Molecular and Cellular Proteomics. 18, 8, p. 1630-1650 21 p.

    Research output: Contribution to journalArticle