Research output per year
Research output per year
- 47 results
Search results
-
2024
Divergent sensory pathways of sneezing and coughing
Jiang, H., Cui, H., Chen, M., Li, F., Shen, X., Guo, C. J., Hoekel, G. E., Zhu, Y., Han, L., Wu, K., Holtzman, M. J. & Liu, Q., Oct 17 2024, In: Cell. 187, 21, p. 5981-5997.e14Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
2023
Dry eye disease in mice activates adaptive corneal epithelial regeneration distinct from constitutive renewal in homeostasis
Lin, J. B., Shen, X., Pfeifer, C. W., Shiau, F., Santeford, A., Ruzycki, P. A., Clark, B. S., Huang, A. J. W., Apte, R. S. & Liu, Q., Jan 10 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 2, e2204134120.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
Pain and itch coding mechanisms of polymodal sensory neurons
Guo, C., Jiang, H., Huang, C. C., Li, F., Olson, W., Yang, W., Fleming, M., Yu, G., Hoekel, G., Luo, W. & Liu, Q., Nov 28 2023, In: Cell Reports. 42, 11, 113316.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
2022
Estrogen metabolites increase nociceptor hyperactivity in a mouse model of uterine pain
Xie, Z., Feng, J., Cai, T., McCarthy, R., Eschbach, M. D., Wang, Y., Zhao, Y., Yi, Z., Zang, K., Yuan, Y., Hu, X., Li, F., Liu, Q., Das, A., England, S. K. & Hu, H., May 23 2022, In: JCI Insight. 7, 10, e149107.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Glutamate in primary afferents is required for itch transmission
Cui, L., Guo, J., Cranfill, S. L., Gautam, M., Bhattarai, J., Olson, W., Beattie, K., Challis, R. C., Wu, Q., Song, X., Raabe, T., Gradinaru, V., Ma, M., Liu, Q. & Luo, W., Mar 2 2022, In: Neuron. 110, 5, p. 809-823.e5Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
IL-33 signaling in sensory neurons promotes dry skin itch
Trier, A. M., Mack, M. R., Fredman, A., Tamari, M., Ver Heul, A. M., Zhao, Y., Guo, C. J., Avraham, O., Ford, Z. K., Oetjen, L. K., Feng, J., Dehner, C., Coble, D., Badic, A., Joshita, S., Kubo, M., Gereau, R. W., Alexander-Brett, J., Cavalli, V. & Davidson, S. & 3 others, , Apr 2022, In: Journal of Allergy and Clinical Immunology. 149, 4, p. 1473-1480.e6Research output: Contribution to journal › Article › peer-review
Open Access78 Scopus citations -
Miswiring of Merkel cell and pruriceptive C fiber drives the itch-scratch cycle
Feng, J., Zhao, Y., Xie, Z., Zang, K., Sviben, S., Hu, X., Fitzpatrick, J. A. J., Wen, L., Liu, Y., Wang, T., Lawson, K., Liu, Q., Yan, Y., Dong, X., Han, L., Wu, G. F., Kim, B. S. & Hu, H., Jul 13 2022, In: Science translational medicine. 14, 653, eabn4819.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
Peripheral Mechanisms of Itch
Guo, C. J., Grabinski, N. S. & Liu, Q., Jan 2022, In: Journal of Investigative Dermatology. 142, 1, p. 31-41 11 p.Research output: Contribution to journal › Review article › peer-review
Open Access20 Scopus citations -
TRPC3 Antagonizes Pruritus in a Mouse Contact Dermatitis Model
Beattie, K., Jiang, H., Gautam, M., MacVittie, M. K., Miller, B., Ma, M., Liu, Q. & Luo, W., Apr 2022, In: Journal of Investigative Dermatology. 142, 4, p. 1136-1144 9 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
2021
A basophil-neuronal axis promotes itch
Wang, F., Trier, A. M., Li, F., Kim, S., Chen, Z., Chai, J. N., Mack, M. R., Morrison, S. A., Hamilton, J. D., Baek, J., Yang, T. L. B., Ver Heul, A. M., Xu, A. Z., Xie, Z., Dong, X., Kubo, M., Hu, H., Hsieh, C. S., Dong, X. & Liu, Q. & 4 others, , Jan 21 2021, In: Cell. 184, 2, p. 422-440.e17Research output: Contribution to journal › Article › peer-review
Open Access177 Scopus citations -
Longitudinal intravital imaging nerve degeneration and sprouting in the toes of spared nerve injured mice
Yeh, H. Y., Lee, J. C., Chi, H. H., Chen, C. C., Liu, Q. & Yen, C. T., Aug 2021, In: Journal of Comparative Neurology. 529, 12, p. 3247-3264 18 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Sneezing reflex is mediated by a peptidergic pathway from nose to brainstem
Li, F., Jiang, H., Shen, X., Yang, W., Guo, C., Wang, Z., Xiao, M., Cui, L., Luo, W., Kim, B. S., Chen, Z., Huang, A. J. W. & Liu, Q., Jul 8 2021, In: Cell. 184, 14, p. 3762-3773.e10Research output: Contribution to journal › Article › peer-review
Open Access48 Scopus citations -
2020
Kallikrein 7 Promotes Atopic Dermatitis-Associated Itch Independently of Skin Inflammation
Guo, C. J., Mack, M. R., Oetjen, L. K., Trier, A. M., Council, M. L., Pavel, A. B., Guttman-Yassky, E., Kim, B. S. & Liu, Q., Jun 2020, In: Journal of Investigative Dermatology. 140, 6, p. 1244-1252.e4Research output: Contribution to journal › Article › peer-review
Open Access46 Scopus citations -
Quantitative Characterization of the Neuropeptide Level Changes in Dorsal Horn and Dorsal Root Ganglia Regions of the Murine Itch Models
Tillmaand, E. G., Anapindi, K. D. B., De La Toba, E. A., Guo, C. J., Krebs, J., Lenhart, A. E., Liu, Q. & Sweedler, J. V., Mar 6 2020, In: Journal of Proteome Research. 19, 3, p. 1248-1257 10 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
2019
Discovery of Benzamidine- And 1-Aminoisoquinoline-Based Human MAS-Related G-Protein-Coupled Receptor X1 (MRGPRX1) Agonists
Prchalová, E., Hin, N., Thomas, A. G., Veeravalli, V., Ng, J., Alt, J., Rais, R., Rojas, C., Li, Z., Hihara, H., Aoki, M., Yoshizawa, K., Nishioka, T., Suzuki, S., Kopajtic, T., Chatrath, S., Liu, Q., Dong, X., Slusher, B. S. & Tsukamoto, T., Sep 26 2019, In: Journal of Medicinal Chemistry. 62, 18, p. 8631-8641 11 p.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
Facilitation of MrgprD by TRP-A1 promotes neuropathic pain
Wang, C., Gu, L., Ruan, Y., Geng, X., Xu, M., Yang, N., Yu, L., Jiang, Y., Zhu, C., Yang, Y., Zhou, Y., Guan, X., Luo, W., Liu, Q., Dong, X., Yu, G., Lan, L. & Tang, Z., Jan 2019, In: FASEB Journal. 33, 1, p. 1360-1373 14 p.Research output: Contribution to journal › Article › peer-review
Open Access60 Scopus citations -
TRESK K+ channel activity regulates trigeminal nociception and headache
Guo, Z., Qiu, C. S., Jiang, X., Zhang, J., Li, F., Liu, Q., Dhaka, A. & Cao, Y. Q., Jul 1 2019, In: eNeuro. 6, 4, ENEURO.0236-19.2019.Research output: Contribution to journal › Article › peer-review
Open Access28 Scopus citations -
TRPV1 activity and substance P release are required for corneal cold nociception
Li, F., Yang, W., Jiang, H., Guo, C., Huang, A. J. W., Hu, H. & Liu, Q., Dec 1 2019, In: Nature communications. 10, 1, 5678.Research output: Contribution to journal › Article › peer-review
Open Access80 Scopus citations -
2018
Anatomical and functional dichotomy of ocular itch and pain
Huang, C. C., Yang, W., Guo, C., Jiang, H., Li, F., Xiao, M., Davidson, S., Yu, G., Duan, B., Huang, T., Huang, A. J. W. & Liu, Q., Aug 1 2018, In: Nature medicine. 24, 8, p. 1268-1276 9 p.Research output: Contribution to journal › Article › peer-review
Open Access57 Scopus citations -
Conopeptides promote itch through human itch receptor hMgprX1
Espino, S. S., Robinson, S. D., Safavi-Hemami, H., Gajewiak, J., Yang, W., Olivera, B. M. & Liu, Q., Nov 2018, In: Toxicon. 154, p. 28-34 7 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
Matrine inhibits itching by lowering the activity of calcium channel
Geng, X., Shi, H., Ye, F., Du, H., Qian, L., Gu, L., Wu, G., Zhu, C., Yang, Y., Wang, C., Zhou, Y., Yu, G., Liu, Q., Dong, X., Yu, L. & Tang, Z., Dec 1 2018, In: Scientific reports. 8, 1, 11328.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
Transient receptor potential vanilloid 4–expressing macrophages and keratinocytes contribute differentially to allergic and nonallergic chronic itch
Luo, J., Feng, J., Yu, G., Yang, P., Mack, M. R., Du, J., Yu, W., Qian, A., Zhang, Y., Liu, S., Yin, S., Xu, A., Cheng, J., Liu, Q., O'Neil, R. G., Xia, Y., Ma, L., Carlton, S. M., Kim, B. S. & Renner, K. & 2 others, , Feb 2018, In: Journal of Allergy and Clinical Immunology. 141, 2, p. 608-619.e7Research output: Contribution to journal › Article › peer-review
Open Access90 Scopus citations -
2017
A novel TRPM8 agonist relieves dry eye discomfort
Yang, J. M., Li, F., Liu, Q., Rüedi, M., Wei, E. T., Lentsman, M., Lee, H. S., Choi, W., Kim, S. J. & Yoon, K. C., Jun 26 2017, In: BMC Ophthalmology. 17, 1, 101.Research output: Contribution to journal › Article › peer-review
Open Access43 Scopus citations -
Leaky Gate Model: Intensity-Dependent Coding of Pain and Itch in the Spinal Cord
Sun, S., Xu, Q., Guo, C., Guan, Y., Liu, Q. & Dong, X., Feb 22 2017, In: Neuron. 93, 4, p. 840-853.e5Research output: Contribution to journal › Article › peer-review
Open Access110 Scopus citations -
Sensory Neurons Co-opt Classical Immune Signaling Pathways to Mediate Chronic Itch
Oetjen, L. K., Mack, M. R., Feng, J., Whelan, T. M., Niu, H., Guo, C. J., Chen, S., Trier, A. M., Xu, A. Z., Tripathi, S. V., Luo, J., Gao, X., Yang, L., Hamilton, S. L., Wang, P. L., Brestoff, J. R., Council, M. L., Brasington, R., Schaffer, A. & Brombacher, F. & 8 others, , Sep 21 2017, In: Cell. 171, 1, p. 217-228.e13Research output: Contribution to journal › Article › peer-review
Open Access790 Scopus citations -
TRPC3 Is Dispensable for β-Alanine Triggered Acute Itch
Dong, P., Guo, C., Huang, S., Ma, M., Liu, Q. & Luo, W., Dec 1 2017, In: Scientific reports. 7, 1, 13869.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
2016
A histamine-independent itch pathway is required for allergic ocular itch
Huang, C. C., Kim, Y. S., Olson, W. P., Li, F., Guo, C., Luo, W., Huang, A. J. W. & Liu, Q., Apr 1 2016, In: Journal of Allergy and Clinical Immunology. 137, 4, p. 1267-1270.e6Research output: Contribution to journal › Article › peer-review
Open Access28 Scopus citations -
Enhanced itch elicited by capsaicin in a chronic itch model
Yu, G., Yang, N., Li, F., Chen, M., Guo, C. J., Wang, C., Hu, D., Yang, Y., Zhu, C., Wang, Z., Shi, H., Gegen, T., Tang, M., He, Q., Liu, Q. & Tang, Z., Apr 23 2016, In: Molecular Pain. 12Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Voltage-gated potassium channels involved in regulation of physiological function in MrgprA3-specific itch neurons
Tang, M., Wu, G., Wang, Z., Yang, N., Shi, H., He, Q., Zhu, C., Yang, Y., Yu, G., Wang, C., Yuan, X., Liu, Q., Guan, Y., Dong, X. & Tang, Z., Apr 1 2016, In: Brain Research. 1636, p. 161-171 11 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
2015
Pirt contributes to uterine contraction-induced pain in mice
Wang, C., Wang, Z., Yang, Y., Zhu, C., Wu, G., Yu, G., Jian, T., Yang, N., Shi, H., Tang, M., He, Q., Lan, L., Liu, Q., Guan, Y., Dong, X., Duan, J. & Tang, Z., Sep 17 2015, In: Molecular Pain. 11, 1, 57.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
The role of the mrgpr receptor family in Itch
Liu, Q., Liu, Q., Liu, Q., Dong, X. & Dong, X., 2015, In: Handbook of Experimental Pharmacology. 226, p. 71-88 18 p.Research output: Contribution to journal › Article › peer-review
51 Scopus citations -
Transient receptor potential A1 activation prolongs isoflurane induction latency and impairs respiratory function in mice
Li, F., Guo, C. J., Huang, C. C., Yu, G., Brown, S. M., Xu, S. & Liu, Q., Apr 20 2015, In: Anesthesiology. 122, 4, p. 768-775 8 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
2014
Activation of MrgC receptor inhibits N-type calcium channels in small-diameter primary sensory neurons in mice
Li, Z., He, S. Q., Xu, Q., Yang, F., Tiwari, V., Liu, Q., Tang, Z., Han, L., Chu, Y. X., Wang, Y., Hin, N., Tsukamoto, T., Slusher, B., Guan, X., Wei, F., Raja, S. N., Dong, X. & Guan, Y., Aug 2014, In: Pain. 155, 8, p. 1613-1621 9 p.Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
Balloon aortic valvuloplasty as a bridge to liver transplantation in patients with severe aortic stenosis: A case series
Kalarickal, P., Liu, Q., Rathor, R., Ishag, S., Kerr, T. & Kangrga, I., 2014, In: Transplantation Proceedings. 46, 10, p. 3492-3495 4 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
MrgC agonism at central terminals of primary sensory neurons inhibits neuropathic pain
He, S. Q., Li, Z., Chu, Y. X., Han, L., Xu, Q., Li, M., Yang, F., Liu, Q., Tang, Z., Wang, Y., Hin, N., Tsukamoto, T., Slusher, B., Tiwari, V., Shechter, R., Wei, F., Raja, S. N., Dong, X. & Guan, Y., Mar 2014, In: Pain. 155, 3, p. 534-544 11 p.Research output: Contribution to journal › Article › peer-review
Open Access39 Scopus citations -
Peptidomimetics of Arg-Phe-NH2 as small molecule agonists of Mas-related gene C (MrgC) receptors
Hin, N., Alt, J., Zimmermann, S. C., Delahanty, G., Ferraris, D. V., Rojas, C., Li, F., Liu, Q., Dong, X., Slusher, B. S. & Tsukamoto, T., Nov 1 2014, In: Bioorganic and Medicinal Chemistry. 22, 21, p. 5831-5837 7 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
2013
A subpopulation of nociceptors specifically linked to itch
Han, L., Ma, C., Liu, Q., Weng, H. J., Cui, Y., Tang, Z., Kim, Y., Nie, H., Qu, L., Patel, K. N., Li, Z., McNeil, B., He, S., Guan, Y., Xiao, B., Lamotte, R. H. & Dong, X., Feb 2013, In: Nature neuroscience. 16, 2, p. 174-182 9 p.Research output: Contribution to journal › Article › peer-review
Open Access459 Scopus citations -
2012
Mechanisms of itch evoked by β-alanine
Liu, Q., Sikand, P., Ma, C., Tang, Z., Han, L., Li, Z., Sun, S., LaMotte, R. H. & Dong, X., Oct 17 2012, In: Journal of Neuroscience. 32, 42, p. 14532-14537 6 p.Research output: Contribution to journal › Article › peer-review
Open Access258 Scopus citations -
TLR3 deficiency impairs spinal cord synaptic transmission, central sensitization, and pruritus in mice
Liu, T., Berta, T., Xu, Z. Z., Park, C. K., Zhang, L., Lü, N., Liu, Q., Liu, Y., Gao, Y. J., Liu, Y. C., Ma, Q., Dong, X. & Ji, R. R., Jun 1 2012, In: Journal of Clinical Investigation. 122, 6, p. 2195-2207 13 p.Research output: Contribution to journal › Article › peer-review
Open Access152 Scopus citations -
2011
Pirt, a TRPV1 modulator, is required for histamine-dependent and -independent itch
Patel, K. N., Liu, Q., Meeker, S., Undem, B. J. & Dong, X., 2011, In: PloS one. 6, 5, e20559.Research output: Contribution to journal › Article › peer-review
Open Access55 Scopus citations -
The distinct roles of two GPCRs, MrgprC11 and PAR2, in itch and hyperalgesia
Liu, Q., Weng, H. J., Patel, K. N., Tang, Z., Bai, H., Steinhoff, M. & Dong, X., Jul 12 2011, In: Science signaling. 4, 181, ra45.Research output: Contribution to journal › Article › peer-review
Open Access201 Scopus citations -
TRPA1 is required for histamine-independent, Mas-related G protein-coupled receptor-mediated itch
Wilson, S. R., Gerhold, K. A., Bifolck-Fisher, A., Liu, Q., Patel, K. N., Dong, X. & Bautista, D. M., May 2011, In: Nature neuroscience. 14, 5, p. 595-603 9 p.Research output: Contribution to journal › Article › peer-review
505 Scopus citations -
2010
Mas-related G-protein-coupled receptors inhibit pathological pain in mice
Guan, Y., Liu, Q., Tang, Z., Raja, S. N., Anderson, D. J. & Dong, X., Sep 7 2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 36, p. 15933-15938 6 p.Research output: Contribution to journal › Article › peer-review
Open Access75 Scopus citations -
2009
Sensory Neuron-Specific GPCR Mrgprs Are Itch Receptors Mediating Chloroquine-Induced Pruritus
Liu, Q., Tang, Z., Surdenikova, L., Kim, S., Patel, K. N., Kim, A., Ru, F., Guan, Y., Weng, H. J., Geng, Y., Undem, B. J., Kollarik, M., Chen, Z. F., Anderson, D. J. & Dong, X., Dec 24 2009, In: Cell. 139, 7, p. 1353-1365 13 p.Research output: Contribution to journal › Article › peer-review
Open Access668 Scopus citations -
2008
Agonists of the Mas-related gene (Mrgs) orphan receptors as novel mediators of mast cell-sensory nerve interactions
Lee, M. G., Dong, X., Liu, Q., Patel, K. N., Choi, O. H., Vonakis, B. & Undem, B. J., Feb 15 2008, In: Journal of Immunology. 180, 4, p. 2251-2255 5 p.Research output: Contribution to journal › Article › peer-review
Open Access39 Scopus citations -
Pirt, a Phosphoinositide-Binding Protein, Functions as a Regulatory Subunit of TRPV1
Kim, A. Y., Tang, Z., Liu, Q., Patel, K. N., Maag, D., Geng, Y. & Dong, X., May 2 2008, In: Cell. 133, 3, p. 475-485 11 p.Research output: Contribution to journal › Article › peer-review
Open Access175 Scopus citations -
2007
Molecular genetic visualization of a rare subset of unmyelinated sensory neurons that may detect gentle touch
Liu, Q., Vrontou, S., Rice, F. L., Zylka, M. J., Dong, X. & Anderson, D. J., Aug 2007, In: Nature neuroscience. 10, 8, p. 946-948 3 p.Research output: Contribution to journal › Article › peer-review
178 Scopus citations