Research output per year
Research output per year
Personal profile
Research interests
My interests are in studying molecular biology in critical care syndromes. I use multidimensional biological and clinical data to find biologically homogeneous subgroups in ARDS and sepsis with a view to developing precision-based care in the ICU. I also have keen interest in Data Science and use cutting-edge tools to understand biological data at a population-wide level. Through these novel tools I hope to improve patient outcomes by matching the right therapies to the right patient at the right time.
Areas of Clinical Interest
Critical care, emergency medicine, acute respiratory failure ARDS post-operative care.
Keywords
- COVID-19
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Latent class analysis-derived subphenotypes are generalisable to observational cohorts of acute respiratory distress syndrome: A prospective study
Sinha, P., Delucchi, K. L., Chen, Y., Zhuo, H., Abbott, J., Wang, C., Wickersham, N., McNeil, J. B., Jauregui, A., Ke, S., Vessel, K., Gomez, A., Hendrickson, C. M., Kangelaris, K. N., Sarma, A., Leligdowicz, A., Liu, K. D., Matthay, M. A., Ware, L. B. & Calfee, C. S., Jan 1 2022, In: Thorax. 77, 1, p. 13-21 9 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Six-month and 12-month patient outcomes based on inflammatory subphenotypes in sepsis-associated ARDS: Secondary analysis of SAILS-ALTOS trial
Hashem, M. D., Hopkins, R. O., Colantuoni, E., Dinglas, V. D., Sinha, P., Aronson Friedman, L., Morris, P. E., Jackson, J. C., Hough, C. L., Calfee, C. S. & Needham, D. M., Jan 1 2022, In: Thorax. 77, 1, p. 22-30 9 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
A neutrophil subset defined by intracellular olfactomedin 4 is associated with mortality in sepsis
Kangelaris, K. N., Clemens, R., Fang, X., Jauregui, A., Liu, T., Vessel, K., Deiss, T., Sinha, P., Leligdowicz, A., Liu, K. D., Zhuo, H., Alder, M. N., Wong, H. R., Calfee, C. S., Lowell, C. & Matthay, M. A., May 2021, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 320, 5, p. L892-L902Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Assessing the importance of interleukin-6 in COVID-19 – Authors' reply
Leisman, D. E., Ronner, L., Pinotti, R., Taylor, M. D., Sinha, P., Calfee, C. S., Hirayama, A. V., Mastroianni, F., Turtle, C. J., Harhay, M. O., Legrand, M. & Deutschman, C. S., Feb 2021, In: The Lancet Respiratory Medicine. 9, 2, p. e14-e15Research output: Contribution to journal › Letter › peer-review
Open Access2 Scopus citations -
Biological Mechanisms of Cognitive and Physical Impairments after Critical Care Rethinking the Inflammatory Model?
Parker, A. M., Sinha, P. & Needham, D. M., Mar 15 2021, In: American journal of respiratory and critical care medicine. 203, 6, p. 665-667 3 p.Research output: Contribution to journal › Editorial
Open Access1 Scopus citations