Personal profile

Research interests

My interests are in studying molecular biology in critical care syndromes. I use multidimensional biological and clinical data to find biologically homogeneous subgroups in ARDS and sepsis with a view to developing precision-based care in the ICU. I also have keen interest in Data Science and use cutting-edge tools to understand biological data at a population-wide level. Through these novel tools I hope to improve patient outcomes by matching the right therapies to the right patient at the right time.

Clinical interests

Critical care, emergency medicine, acute respiratory failure ARDS post-operative care.

Keywords

  • COVID-19

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Collaborations and top research areas from the last five years

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  • Advancing specificity in delirium: The delirium subtyping initiative

    Bowman, E. M. L., Brummel, N. E., Caplan, G. A., Cunningham, C., Evered, L. A., Fiest, K. M., Girard, T. D., Jackson, T. A., LaHue, S. C., Lindroth, H. L., Maclullich, A. M. J., McAuley, D. F., Oh, E. S., Oldham, M. A., Page, V. J., Pandharipande, P. P., Potter, K. M., Sinha, P., Slooter, A. J. C. & Sweeney, A. M. & 5 others, Tieges, Z., Van Dellen, E., Wilcox, M. E., Zetterberg, H. & Cunningham, E. L., Jan 2024, In: Alzheimer's and Dementia. 20, 1, p. 183-194 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    8 Scopus citations
  • Causes and attributable fraction of death from ARDS in inflammatory phenotypes of sepsis

    Evrard, B., Sinha, P., Delucchi, K., Hendrickson, C. M., Kangelaris, K. N., Liu, K. D., Willmore, A., Wu, N., Neyton, L., Schmiege, E., Gomez, A., Kerchberger, V. E., Zalucky, A., Matthay, M. A., Ware, L. B. & Calfee, C. S., Dec 2024, In: Critical Care. 28, 1, 164.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study

    IMPACC Network, IMPACC Steering Committee, Clinical & Data Coordinating Center (CDCC), IMPACC Data Analysis Group, IMPACC Site Investigators, IMPACC Core Laboratory, IMPACC Clinical Study Team, Ozonoff, A., Jayavelu, N. D., Liu, S., Melamed, E., Milliren, C. E., Qi, J., Geng, L. N., McComsey, G. A., Cairns, C. B., Baden, L. R., Schaenman, J., Shaw, A. C. & Samaha, H. & 187 others, Seyfert-Margolis, V., Krammer, F., Rosen, L. B., Steen, H., Syphurs, C., Dandekar, R., Shannon, C. P., Sekaly, R. P., Ehrlich, L. I. R., Corry, D. B., Kheradmand, F., Atkinson, M. A., Brakenridge, S. C., Agudelo Higuita, N. I., Metcalf, J. P., Hough, C. L., Messer, W. B., Pulendran, B., Nadeau, K. C., Davis, M. M., Sesma, A. F., Simon, V., van Bakel, H., Kim-Schulze, S., Hafler, D. A., Levy, O., Kraft, M., Bime, C., Haddad, E. K., Calfee, C. S., Erle, D. J., Langelier, C. R., Eckalbar, W., Bosinger, S. E., Peters, B., Kleinstein, S. H., Reed, E. F., Augustine, A. D., Diray-Arce, J., Maecker, H. T., Altman, M. C., Montgomery, R. R., Becker, P. M., Rouphael, N., McEnaney, K., Barton, B., Lentucci, C., Saluvan, M., Chang, A. C., Hoch, A., Albert, M., Shaheen, T., Kho, A. T., Thomas, S., Chen, J., Murphy, M. D., Cooney, M., Hayati, A. N., Bryant, R., Abraham, J., Presnell, S., Jancsyk, T., Maguire, C., Lee, B., Fourati, S., Esserman, D. A., Guan, L., Gygi, J., Pawar, S., Brito, A., Fragiadakis, G. K., Patel, R., Tebbutt, S. J., Overton, J. A., Vita, R., Westendorf, K., Thyagarajan, R. V., Rousseau, J. F., Wylie, D., Triplett, T. A., Kojic, E., Chinthrajah, S., Ahuja, N., Rogers, A. J., Artandi, M., Yendewa, G., Powell, D. L., Kim, J. N., Simmons, B., Michael Goonewardene, I., Smith, C. M., Martens, M., Sherman, A. C., Walsh, S. R., Issa, N. C., Salehi-Rad, R., Dela Cruz, C., Farhadian, S., Iwasaki, A., Ko, A. I., Anderson, E. J., Mehta, A. K., Sevransky, J. E., Leligdowicz, A., Matthay, M. A., Singer, J. P., Kangelaris, K. N., Hendrickson, C. M., Krummel, M. F., Woodruff, P. G., Anderson, M. L., Guirgis, F. W., Drevets, D. A., Brown, B. R., Siegel, S. A. R., Lu, Z., Mosier, J., Kimura, H., Khor, B., Rahman, A., Stadlbauer, D., Dutta, J., Gonzalez-Reiche, A. S., Van de Guchte, A., Carreño, J. M., Singh, G., Raskin, A., Tcheou, J., Bielak, D., Kawabata, H., Xie, H., Kelly, G., Patel, M., Nie, K., Yellin, T., Fried, M., Sullivan, L., Morris, S., Sieg, S., van Zalm, P., Fatou, B., Mendez, K., Lasky-Su, J., Hutton, S. R., Michelotti, G., Wong, K., Jha, M., Viode, A., Kanarek, N., Petrova, B., Zhao, Y., Boddapati, A. K., Tharp, G. K., Pellegrini, K. L., Beagle, E., Cowan, D., Hamilton, S., Ribeiro, S. P., Hodder, T., Lee, S., Wilson, M. R., Alvarenga, B., Rajan, J., Schroeder, A., Tsitsiklis, A., Mick, E., Guerrero, Y. S., Love, C., Maliskova, L., Adkisson, M., Siles, N., Geltman, J., Hurley, K., Saksena, M., Altman, D., Srivastava, K., Eaker, L. Q., Bermúdez-González, M. C., Beach, K. F., Sominsky, L. A., Azad, A. R., Mulder, L. C. F., Kleiner, G., Lee, A. S., Do, E., Fernandes, A. & Sinha, P., Dec 2024, In: Nature communications. 15, 1, 216.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    16 Scopus citations
  • Host and Microbe Blood Metagenomics Reveals Key Pathways Characterizing Critical Illness Phenotypes

    Neyton, L. P. A., Sinha, P., Sarma, A., Mick, E., Kalantar, K., Chen, S., Wu, N., Delucchi, K., Zhuo, H., Bos, L. D. J., Jauregui, A., Gomez, A., Hendrickson, C. M., Kangelaris, K. N., Leligdowicz, A., Liu, K. D., Matthay, M. A., Langelier, C. R. & Calfee, C. S., Apr 1 2024, In: American journal of respiratory and critical care medicine. 209, 7, p. 805-815 11 p.

    Research output: Contribution to journalArticlepeer-review

    7 Scopus citations
  • IgM N-glycosylation correlates with COVID-19 severity and rate of complement deposition

    IMPACC Data Analysis Group, IMPACC Site Investigators, IMPACC Core Laboratory, IMPACC Clinical Study Team, IMPACC Network, IMPACC Steering Committee, Clinical & Data Coordinating Center (CDCC), Haslund-Gourley, B. S., Woloszczuk, K., Hou, J., Connors, J., Cusimano, G., Bell, M., Taramangalam, B., Fourati, S., Mege, N., Bernui, M., Altman, M. C., Krammer, F. & van Bakel, H. & 187 others, Maecker, H. T., Rouphael, N., Diray-Arce, J., Wigdah, B., Kutzler, M. A., Cairns, C. B., Haddad, E. K., Comunale, M. A., Ozonoff, A., Ehrlich, L. I. R., Melamed, E., Sesma, A. F., Simon, V., Pulendran, B., Nadeau, K. C., Davis, M. M., McCoey, G. A., Sekaly, R., Baden, L. R., Levy, O., Schaenman, J., Reed, E. F., Shaw, A. C., Hafler, D. A., Montgomery, R. R., Kleinstein, S. H., Becker, P. M., Augustine, A. D., Calfee, C. S., Erle, D. J., Debakey, M. E., Corry, D. B., Kheradmand, F., Atkinson, M. A., Brakenridge, S. C., Agudelo Higuita, N. I., Metcalf, J. P., Hough, C. L., Messer, W. B., Kraft, M., Bime, C., Peters, B., Milliren, C. E., Syphurs, C., McEnaney, K., Barton, B., Lentucci, C., Saluvan, M., Chang, A. C., Hoch, A., Albert, M., Shaheen, T., Kho, A. T., Liu, S., Thomas, S., Chen, J., Murphy, M. D., Cooney, M., Hayati, A. N., Bryant, R., Abraham, J., Jayavelu, N. D., Presnell, S., Jancsyk, T., Maguire, C., Qi, J., Lee, B., Esserman, D. A., Guan, L., Gygi, J., Pawar, S., Brito, A., Fragiadakis, G. K., Patel, R., Overton, J. A., Vita, R., Westendorf, K., Shannon, C. P., Tebbutt, S. J., Thyagarajan, R. V., Rousseau, J. F., Wylie, D., Triplett, T. A., Kojic, E., Chinthrajah, S., Ahuja, N., Rogers, A. J., Artandi, M., Geng, L., Yendewa, G., Powell, D. L., Kim, J. N., Simmons, B., Goonewardene, I. M., Smith, C. M., Martens, M., Sherman, A. C., Walsh, S. R., Issa, N. C., Salehi-Rad, R., Dela Cruz, C., Farhadian, S., Iwasaki, A., Ko, A. I., Anderson, E. J., Mehta, A. K., Sevransky, J. E., Seyfert-Margolis, V., Leligdowicz, A., Matthay, M. A., Singer, J. P., Kangelaris, K. N., Hendrickson, C. M., Krummel, M. F., Langelier, C. R., Woodruff, P. G., Anderson, M. L., Guirgis, F. W., Drevets, D. A., Brown, B. R., Siegel, S. A. R., Lu, Z., Mosier, J., Kimura, H., Khor, B., Rahman, A., Stadlbauer, D., Dutta, J., Xie, H., Kim-Schulze, S., Gonzalez-Reiche, A. S., van de Guchte, A., Carreño, J. M., Singh, G., Raskin, A., Tcheou, J., Bielak, D., Kawabata, H., Kelly, G., Patel, M., Nie, K., Yellin, T., Fried, M., Sullivan, L., Morris, S., Sieg, S., Steen, H., van Zalm, P., Fatou, B., Mendez, K., Lasky-Su, J., Hutton, S. R., Michelotti, G., Wong, K., Jha, M., Viode, A., Kanarek, N., Petrova, B., Zhao, Y., Bosinger, S. E., Boddapati, A. K., Tharp, G. K., Pellegrini, K. L., Beagle, E., Cowan, D., Hamilton, S., Ribeiro, S. P., Hodder, T., Rosen, L. B., Lee, S., Wilson, M. R., Dandekar, R., Alvarenga, B., Rajan, J., Eckalbar, W., Schroeder, A. W., Tsitsiklis, A., Mick, E., Guerrero, Y. S., Love, C., Maliskova, L., Adkisson, M., Siles, N., Geltman, J., Hurley, K., Saksena, M. & Sinha, P., Dec 2024, In: Nature communications. 15, 1, 404.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    4 Scopus citations