Pietro Mazzoni

Associate Professor of Neurology

    • 4276 Citations
    1986 …2020

    Research output per year

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    Personal profile

    Research interests

    My research focus is motor control abnormalities in movement disorders. This area addresses how neurological disorders, such as Parkinson’s disease and Huntington’s disease, affect our ability to control our movements. We generate hypotheses in the framework of computational motor control, and we devise motor studies of patients with movement disorders to test these hypotheses. The studies use motion capture techniques for detailed recording of reaching movements, gait, and postural responses. We interpret the results to advance our knowledge of how different nervous system circuits contribute to different aspects of motor control, and of how abnormal movements can be understood at the control level. This knowledge can inform on the design of specific rehabilitation strategies and of artificial devices to alleviate symptoms.

    Areas of Clinical Interest

    p.p1 {margin: 0.0px 0.0px 0.0px 0.0px; font: 14.0px Calibri; -webkit-text-stroke: #000000} span.s1 {font-kerning: none} Parkinson's disease, Parkinsonism, tremor, dystonia, myoclonus, chorea, tics, Tourette syndrome, cerebellar ataxia, normal pressure hydrocephalus, tardive dyskinesia, involuntary movements, gait disorders, freezing of gait p.p1 {margin: 0.0px 0.0px 0.0px 0.0px; font: 14.0px Calibri; -webkit-text-stroke: #000000} span.s1 {font-kerning: none}

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    Research Output

    Design of the WHIP-PD study: A phase II, twelve-month, dual-site, randomized controlled trial evaluating the effects of a cognitive-behavioral approach for promoting enhanced walking activity using mobile health technology in people with Parkinson-disease

    Rawson, K. S., Cavanaugh, J. T., Colon-Semenza, C., Deangelis, T., Duncan, R. P., Fulford, D., Lavalley, M. P., Mazzoni, P., Nordahl, T., Quintiliani, L. M., Saint-Hilaire, M., Thomas, C. A., Earhart, G. M. & Ellis, T. D., Apr 20 2020, In : BMC Neurology. 20, 1, 146.

    Research output: Contribution to journalArticle

    Open Access
  • Gait Cycle Validation and Segmentation Using Inertial Sensors

    Prateek, G. V., Mazzoni, P., Earhart, G. M. & Nehorai, A., Aug 2020, In : IEEE Transactions on Biomedical Engineering. 67, 8, p. 2132-2144 13 p., 8911215.

    Research output: Contribution to journalArticle

  • 1 Scopus citations

    Predicting Cognitive Improvement in Normal Pressure Hydrocephalus Patients Using Preoperative Neuropsychological Testing and Cerebrospinal Fluid Biomarkers

    McGovern, R. A., Nelp, T. B., Kelly, K. M., Chan, A. K., Mazzoni, P., Sheth, S. A., Honig, L. S., Teich, A. F. & McKhann, G. M., Oct 1 2019, In : Clinical Neurosurgery. 85, 4, p. E662-E669

    Research output: Contribution to journalArticle

  • 2 Scopus citations

    A single, continuously applied control policy for modeling reaching movements with and without perturbation

    Li, Z., Mazzoni, P., Song, S. & Qian, N., Feb 1 2018, In : Neural Computation. 30, 2, p. 397-427 31 p.

    Research output: Contribution to journalLetter

  • 1 Scopus citations

    High and low levels of an NTRK2-driven genetic profile affect motor- and cognition-associated frontal gray matter in prodromal Huntington’s disease

    PREDICT-HD Investigators and Coordinators of the Huntington, Jul 2018, In : Brain Sciences. 8, 7, 116.

    Research output: Contribution to journalArticle

    Open Access
  • 1 Scopus citations