• 9491 Citations

Research output per year

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Personal profile

Research interests

Research areas of interest include the clinical effects of the storage lesion of red blood cells and platelets, the use of functional coagulation monitoring to improve the efficacy of blood component transfusions and reduce the risk of severe thrombotic events in critical illness, and optimizing transfusion strategies and outcomes for patients in hemorrhagic shock. Storage lesion mechanisms that are being explored include the dysregulation of immune, coagulation, and endothelial function with the transfusion of blood products of increased storage age in critically ill patients.

Areas of Clinical Interest

pediatric intensive care,


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Research Output

An international survey on the use of low titer group O whole blood for the resuscitation of civilian trauma patients in 2020

Yazer, M. H. & Spinella, P. C., Jun 1 2020, In : Transfusion. 60, S3, p. S176-S179

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Clinical controversies in anticoagulation monitoring and antithrombin supplementation for ECMO

Chlebowski, M. M., Baltagi, S., Carlson, M., Levy, J. H. & Spinella, P. C., Jan 20 2020, In : Critical Care. 24, 1, 19.

Research output: Contribution to journalReview article

Open Access
  • 5 Scopus citations

    Current advances in transfusion medicine: a 2019 review of selected topics from the AABB Clinical Transfusion Medicine Committee

    Pagano, M. B., Allen, E. S., Chou, S. T., Dunbar, N. M., Gniadek, T., Goel, R., Harm, S. K., Hopkins, C. K., Jacobson, J., Lokhandwala, P. M., Metcalf, R. A., Raval, J. S., Schwartz, J., Shan, H., Spinella, P. C., Storch, E. & Cohn, C. S., Jan 1 2020, (Accepted/In press) In : Transfusion.

    Research output: Contribution to journalArticle

  • Early Use of Adjunctive Therapies for Pediatric Acute Respiratory Distress Syndrome: A PARDIE Study

    Rowan, C. M., Klein, M. J., Hsing, D. D., Dahmer, M. K., Spinella, P. C., Emeriaud, G., Hassinger, A. B., Piñeres-Olave, B. E., Flori, H. R., Haileselassie, B., Lopez-Fernandez, Y. M., Chima, R. S., Shein, S. L., Maddux, A. B., Lillie, J., Izquierdo, L., Kneyber, M. C. J., Smith, L. S., Khemani, R. G., Thomas, N. J. & 1 others, Yehya, N., Jun 1 2020, In : American journal of respiratory and critical care medicine. 201, 11, p. 1389-1397 9 p.

    Research output: Contribution to journalArticle

  • 1 Scopus citations

    Effect of platelet storage duration on clinical outcomes and incremental platelet change in critically ill children

    Nellis, M. E., Spinella, P. C., Tucci, M., Stanworth, S. J., Steiner, M. E., Cushing, M. M., Davis, P. J. & Karam, O., 2020, (Accepted/In press) In : Transfusion.

    Research output: Contribution to journalArticle