• 14195 Citations
1971 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Personal profile

Research interests

Our laboratory is studying DNA replication and DNA damage response mechanisms in the yeast Saccharomyces cerevisiae and in human cells. Yeast is an ideal eukaryotic organism to study these pathways, both at a genetic and at a biochemical level. It is important to understand these mechanisms in yeast because defects in the highly analogous pathways in humans are known to result in damage susceptibility and show a predisposition to various forms of cancer.

Fingerprint Dive into the research topics where Peter Burgers is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 9 Similar Profiles

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output

Bypass of DNA interstrand crosslinks by a Rev1-DNA polymerase ζ complex

Bezalel-Buch, R., Cheun, Y. K., Roy, U., Schärer, O. D. & Burgers, P. M., Sep 4 2020, In : Nucleic acids research. 48, 15, p. 8461-8473 13 p.

Research output: Contribution to journalArticle

Open Access
  • Cryo-EM Structure of Nucleotide-Bound Tel1ATM Unravels the Molecular Basis of Inhibition and Structural Rationale for Disease-Associated Mutations

    Yates, L. A., Williams, R. M., Hailemariam, S., Ayala, R., Burgers, P. & Zhang, X., Jan 7 2020, In : Structure. 28, 1, p. 96-104.e3

    Research output: Contribution to journalArticle

    Open Access
  • 5 Scopus citations

    Modeling cancer genomic data in yeast reveals selection against ATM function during tumorigenesis

    Hohl, M., Mojumdar, A., Hailemariam, S., Kuryavyi, V., Ghisays, F., Sorenson, K., Chang, M., Taylor, B. S., Patel, D. J., Burgers, P. M., Cobb, J. A. & Petrini, J. H. J., Mar 2020, In : PLoS genetics. 16, 3, e1008422.

    Research output: Contribution to journalArticle

    Open Access
  • Activation of Tel1ATM kinase requires Rad50 ATPase and long nucleosome-free DNA but no DNA ends

    Hailemariam, S., Kumar, S. & Burgers, P. M., Jun 28 2019, In : Journal of Biological Chemistry. 294, 26, p. 10120-10130 11 p.

    Research output: Contribution to journalArticle

  • 9 Scopus citations

    Complementary roles of Pif1 helicase and single stranded DNA binding proteins in stimulating DNA replication through G-quadruplexes

    Sparks, M. A., Singh, S. P., Burgers, P. M. & Galletto, R., Sep 19 2019, In : Nucleic acids research. 47, 16, p. 8595-8605 11 p.

    Research output: Contribution to journalArticle

    Open Access
  • 7 Scopus citations