• 4547 Citations
1989 …2020

Research output per year

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Personal profile

Research interests

Dr. Kotzbauer’s research is focused on Parkinson’s disease and a group of hereditary disorders called Neurodegeneration with Brain Iron Accumulation. The laboratory uses biochemical analysis, cell culture and mouse models to understand disease mechanisms and to develop new therapeutic approaches for these neurodegenerative disorders.

Areas of Clinical Interest

Parkinson's disease and related disorders, tremor, neurodegeneration with brain iron accumulation (NBIA)

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Research Output

APOE genotype regulates pathology and disease progression in synucleinopathy

Davis, A. A., Inman, C. E., Wargel, Z. M., Dube, U., Freeberg, B. M., Galluppi, A., Haines, J. N., Dhavale, D. D., Miller, R., Choudhury, F. A., Sullivan, P. M., Cruchaga, C., Perlmutter, J. S., Ulrich, J. D., Benitez, B. A., Kotzbauer, P. T. & Holtzman, D. M., Feb 5 2020, In : Science translational medicine. 12, 529, eaay3069.

Research output: Contribution to journalArticle

  • 9 Scopus citations

    Proteinopathy and longitudinal changes in functional connectivity networks in Parkinson disease

    Campbell, M. C., Jackson, J. J., Koller, J. M., Snyder, A. Z., Kotzbauer, P. T. & Perlmutter, J. S., Feb 18 2020, In : Neurology. 94, 7, p. e718-e728

    Research output: Contribution to journalArticle

  • 3 Scopus citations

    Sleep Deprivation Affects Tau Phosphorylation in Human Cerebrospinal Fluid

    Barthélemy, N. R., Liu, H., Lu, W., Kotzbauer, P. T., Bateman, R. J. & Lucey, B. P., May 1 2020, In : Annals of neurology. 87, 5, p. 700-709 10 p.

    Research output: Contribution to journalArticle

  • 5 Scopus citations

    Detection of TAR DNA-binding protein 43 (TDP-43) oligomers as initial intermediate species during aggregate formation

    French, R. L., Grese, Z. R., Aligireddy, H., Dhavale, D. D., Reeb, A. N., Kedia, N., Kotzbauer, P. T., Bieschke, J. & Ayala, Y. M., Apr 26 2019, In : Journal of Biological Chemistry. 294, 17, p. 6696-6709 14 p.

    Research output: Contribution to journalArticle

  • 12 Scopus citations

    Parkinson’s disease and multiple system atrophy have distinct -synuclein seed characteristics

    Yamasaki, T. R., Holmes, B. B., Furman, J. L., Dhavale, D. D., Su, B. W., Song, E. S., Cairns, N. J., Kotzbauer, P. T. & Diamond, M. I., Jan 18 2019, In : Journal of Biological Chemistry. 294, 3, p. 1045-1058 14 p.

    Research output: Contribution to journalArticle

  • 41 Scopus citations