• Source: Scopus
1991 …2020

Research activity per year

If you made any changes in Pure these will be visible here soon.

Personal profile

Research interests

Dr. Hruz is board certified in Pediatrics and Pediatric Endocrinology and Metabolism. Dr. Hruz has clinical interest in a wide range of endocrine disorders, with a special interest in diabetes mellitus. His research efforts are directed toward understanding facilitative glucose transport as it relates to normal and disordered glucose homeostasis. The laboratory is investigating the in vitro and in vivo effects of HIV protease inhibitors on glucose transporter function. The goal of this research is to identify the molecular mechanisms that lead HIV infected patients receiving PIs to develop insulin resistance. The laboratory is also using these isoform-selective antagonists of the insulin-responsive transporter GLUT4 to understand the role of glucose transport in insulin-responsive tissues. Recent efforts have been directed toward understanding the role of glucose transport in the failing heart. This has led to translational research into the understanding of the influence of insulin resistance in pediatric heart failure.

Areas of Clinical Interest

Pediatric endocrinology, pediatric metabolism

Fingerprint

Dive into the research topics where Paul Hruz is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
  • 6 Similar Profiles

Network

Recent external collaboration on country level. Dive into details by clicking on the dots.
If you made any changes in Pure these will be visible here soon.