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Personal profile

Research interests

My research is focused on the development of personalized medicine strategies for cancer using genomic technologies with a particular focus on gene regulatory changes associated with breast cancer. I develop and uses bioinformatics and statistical methods for the analysis of high throughput sequence data and identification of biomarkers for diagnostic, prognostic and drug response prediction.

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Research Output

A harmonized meta-knowledgebase of clinical interpretations of somatic genomic variants in cancer

Variant Interpretation for Cancer Consortium, Apr 1 2020, In : Nature Genetics. 52, 4, p. 448-457 10 p.

Research output: Contribution to journalArticle

Open Access
  • 4 Scopus citations

    A virome sequencing approach to feline oral squamous cell carcinoma to evaluate viral causative factors

    Chu, S., Wylie, T. N., Wylie, K. M., Johnson, G. C., Skidmore, Z. L., Fleer, M., Griffith, O. L. & Bryan, J. N., Jan 2020, In : Veterinary Microbiology. 240, 108491.

    Research output: Contribution to journalArticle

  • 1 Scopus citations

    Collaborative, multidisciplinary evaluation of cancer variants through virtual molecular tumor boards informs local clinical practices

    Rao, S., Pitel, B., Wagner, A. H., Boca, S. M., McCoy, M., King, I., Gupta, S., Park, B. H., Warner, J. L., Chen, J., Rogan, P. K., Chakravarty, D., Griffith, M., Griffith, O. L. & Madhavan, S., 2020, In : JCO Clinical Cancer Informatics. 4, p. 602-613 12 p.

    Research output: Contribution to journalReview article

    Open Access
  • PVACtools: A computational toolkit to identify and visualize cancer neoantigens

    Hundal, J., Kiwala, S., McMichael, J., Miller, C. A., Xia, H., Wollam, A. T., Liu, C. J., Zhao, S., Feng, Y. Y., Graubert, A. P., Wollam, A. Z., Neichin, J., Neveau, M., Walker, J., Gillanders, W. E., Mardis, E. R., Griffith, O. L. & Griffith, M., Mar 1 2020, In : Cancer immunology research. 8, 3, p. 409-420 12 p.

    Research output: Contribution to journalArticle

    Open Access
  • 4 Scopus citations

    Reply

    Barnell, E. K., Kang, Y., Wurtzler, E. M., Griffith, M., Chaudhuri, A. A. & Griffith, O. L., Feb 2020, In : Gastroenterology. 158, 3, p. 793-794 2 p.

    Research output: Contribution to journalLetter

    Open Access