Personal profile
Research interests
I am interested in understanding relationship between obesity and skeletal health. We have reported two epigenetic regulators, regulate macrophage function as well as their differentiation to bone resorbing cells, osteoclast. Genetic deletion as a result leads to profound changes in bone phenotype and also effects immunometabolism.
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Depletion of marrow adipo-CAR cells in mice enhances bone formation by activating bone morphogenetic protein receptor (BMPR) in pre-osteoblasts
Zou, W., Rohatgi, N., Pan, H., Pokhrel, N. K., Silva, M. J. & Teitelbaum, S. L., May 1 2025, In: Journal of Bone and Mineral Research. 40, 5, p. 688-698 11 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Link opens in a new tab Scopus citations -
Tmem178 Negatively Regulates IL-1β Production Through Inhibition of the NLRP3 Inflammasome
Khanna, K., Yan, H., Mehra, M., Rohatgi, N., Mbalaviele, G., Mellins, E. D. & Faccio, R., Jan 2024, In: Arthritis and Rheumatology. 76, 1, p. 107-118 12 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Link opens in a new tab Scopus citations -
BAP1 promotes osteoclast function by metabolic reprogramming
Rohatgi, N., Zou, W., Li, Y., Cho, K., Collins, P. L., Tycksen, E., Pandey, G., DeSelm, C. J., Patti, G. J., Dey, A. & Teitelbaum, S. L., Dec 2023, In: Nature communications. 14, 1, 5923.Research output: Contribution to journal › Article › peer-review
Open Access25 Link opens in a new tab Scopus citations -
ThPOK inhibits osteoclast formation via NFATc1 transcription and function
Zou, W., Izawa, T., Rohatgi, N., Zou, S. Y., Li, Y. & Teitelbaum, S. L., 2023, (Accepted/In press) In: JBMR Plus.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
Conditional loss of IKKα in Osterix + cells has no effect on bone but leads to age-related loss of peripheral fat
Davis, J. L., Pokhrel, N. K., Cox, L., Rohatgi, N., Faccio, R. & Veis, D. J., Dec 2022, In: Scientific reports. 12, 1, 4915.Research output: Contribution to journal › Article › peer-review
Open Access4 Link opens in a new tab Scopus citations