The Murakami Lab’s research focuses on understanding the mechanism of autoimmune kidney diseases and kidney transplant rejection. The immune system in our body is trained to distinguish self (own tissues and cells) and non-self (bacteria or viral pathogens), and to eliminate non-self to protect ourselves from illness. The kidney is one of the most susceptible organs for autoimmune disease, but no specific treatments are available due to lack of fundamental understanding of the disease mechanisms. Our overall goal is to unlock the mechanism of auto- and allo-immunity by studying animal models and patient samples, and to develop therapies for autoimmune kidney diseases and transplant rejection.

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Kidney transplant rejection, Onconephrology, Palliative care for patients living with kidney diseases