Research output per year
Research output per year
Personal profile
Research interests
Our research identified the membrane protein CD36 as a high affinity receptor for long chain fatty acid (FA) and as a signaling protein that plays a key role in metabolic regulation. We recently documented that CD36-mediated signal transduction involves modulation of the assembly/disassembly of proteins in the AMPK and insulin signaling pathways and we are exploring how this affects activity of downstream proteins of FA and glucose metabolism. In humans, we found that variants in the CD36 gene influence blood lipids and risk of metabolic syndrome and more recently endothelial function. We will be exploring the contribution of CD36 polymorphisms to the susceptibility for endothelial dysfunction, a condition that often precedes insulin resistance, inflammation and onset of metabolic pathologies.
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A Single Bout of Premeal Resistance Exercise Improves Postprandial Glucose Metabolism in Obese Men with Prediabetes
Bittel, A. J., Bittel, D. C., Mittendorfer, B., Patterson, B. W., Okunade, A., Abumrad, N. A., Reeds, D. N. & Cade, W. T., Apr 1 2021, In: Medicine and Science in Sports and Exercise. 53, 4, p. 694-703 10 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Autoregulation of insulin receptor signaling through MFGE8 and the αvβ5 integrin
Datta, R., Lizama, C. O., Soltani, A. K., McKleroy, W., Podolsky, M. J., Yang, C. D., Huynh, T. L., Cautivo, K. M., Wang, B., Koliwad, S. K., Abumrad, N. A. & Atabai, K., May 4 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 18, 2102171118.Research output: Contribution to journal › Article › peer-review
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CD36 maintains the gastric mucosa and associates with gastric disease
Jacome-Sosa, M., Miao, Z. F., Peche, V. S., Morris, E. F., Narendran, R., Pietka, K. M., Samovski, D., Lo, H. Y. G., Pietka, T., Varro, A., Love-Gregory, L., Goldenring, J. R., Kuda, O., Gamazon, E. R., Mills, J. C. & Abumrad, N. A., Dec 2021, In: Communications Biology. 4, 1, 1247.Research output: Contribution to journal › Article › peer-review
Open Access -
Endothelial cell CD36 deficiency prevents normal angiogenesis and vascular repair
Khzam, L. B., Son, N. H., Mullick, A. E., Abumrad, N. A. & Goldberg, I. J., 2021, In: American Journal of Translational Research. 12, 12, p. 7737-7761 25 p.Research output: Contribution to journal › Article › peer-review
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Endothelial cell receptors in tissue lipid uptake and metabolism
Abumrad, N. A., Cabodevilla, A. G., Samovski, D., Pietka, T., Basu, D. & Goldberg, I. J., 2021, (Accepted/In press) In: Circulation research. p. 433-450 18 p.Research output: Contribution to journal › Review article › peer-review
3 Scopus citations