If you made any changes in Pure these will be visible here soon.

Personal profile

Research interests

I am a molecular biologist trained in musculoskeletal research, with a focus on understanding the early molecular events that occur in musculoskeletal tissues following injury. Evidence suggests that injury to knee meniscus is associated with an elevated risk for development of osteoarthritis, which affects over 30 million people in the United States. Meniscus injuries are very frequent injury types and are often treated with surgery with annually 690,000 partial meniscectomies being performed in the U.S. It is estimated that 50% of the patients with meniscus injury develop osteoarthritis within 10–20 years. However, it is likely the molecular changes leading to osteoarthritis begin early in that timeframe. Therefore, we seek to answer a critical question: how do molecular degradation and osteoarthritis biomarkers relate to and reflect the status of the knee in patients with an injured meniscus. These findings will help understand early initiation and progression of degenerative changes in the knee joint.

Fingerprint Dive into the research topics where Muhammad Farooq Rai is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 18 Similar Profiles

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output

  • Gene Expression in Meniscal Tears at the Time of Arthroscopic Partial Meniscectomy Predicts the Progression of Osteoarthritis Within 6 Years of Surgery

    Lamplot, J. D., Rai, M. F., Tompkins, W. P., Friedman, M. V., Schmidt, E. J., Sandell, L. J. & Brophy, R. H., 2020, In : Orthopaedic Journal of Sports Medicine. 8, 8

    Research output: Contribution to journalArticle

    Open Access
  • Genetic correlations between cartilage regeneration and degeneration reveal an inverse relationship

    Rai, M. F., Cheverud, J. M., Schmidt, E. J. & Sandell, L., Aug 2020, In : Osteoarthritis and Cartilage. 28, 8, p. 1111-1120 10 p.

    Research output: Contribution to journalArticle

  • Induction of WNT16 via peptide-mRNA nanoparticle-based delivery maintains cartilage homeostasis

    Yan, H., Hu, Y., Akk, A., Rai, M. F., Pan, H., Wickline, S. A. & Pham, C. T. N., Jan 2020, In : Pharmaceutics. 12, 1, 73.

    Research output: Contribution to journalArticle

    Open Access
  • 1 Scopus citations