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Personal profile

Research interests

Specific metabolic requirements of immune cells provide novel promising targets of therapeutic intervention to modulate inflammatory diseases. Bambouskova lab studies how metabolic regulation integrates with immune cell signaling. During her postdoctoral work Monika focused on metabolic rewiring in activating macrophages, particularly on the role of metabolite itaconate in regulation of macrophage inflammatory response. Her work defined a fundamentally novel connection between the cellular stress response and IκBζ-mediated inflammatory axis and its therapeutic impact for a number of autoimmune diseases. Ongoing research program in the lab employs molecular biology and biochemistry techniques together with systems approaches to tackle molecular mechanisms of crosstalk between metabolism and cell signaling in the regulation of immune responses.

Available to Mentor:

  • PhD/MSTP Students

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Collaborations and top research areas from the last five years

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