Research output per year
Research output per year
- 50 - 100 out of 114 results
Search results
-
2016
Systemic disease manifestations associated with epilepsy in tuberous sclerosis complex
Jeong, A. & Wong, M., Sep 1 2016, In: Epilepsia. 57, 9, p. 1443-1449 7 p.Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations -
2015
Effect of chronic administration of low dose rapamycin on development and immunity in young rats
Lu, Z., Liu, F., Chen, L., Zhang, H., Ding, Y., Liu, J., Wong, M. & Zeng, L. H., Aug 6 2015, In: PloS one. 10, 8, e0135256.Research output: Contribution to journal › Article › peer-review
Open Access28 Scopus citations -
Inflammatory mechanisms contribute to the neurological manifestations of tuberous sclerosis complex
Zhang, B., Zou, J., Rensing, N. R., Yang, M. & Wong, M., Aug 1 2015, In: Neurobiology of Disease. 80, p. 70-79 10 p.Research output: Contribution to journal › Article › peer-review
Open Access49 Scopus citations -
Intermittent dosing of rapamycin maintains antiepileptogenic effects in a mouse model of tuberous sclerosis complex
Rensing, N., Han, L. & Wong, M., Jul 1 2015, In: Epilepsia. 56, 7, p. 1088-1097 10 p.Research output: Contribution to journal › Article › peer-review
Open Access42 Scopus citations -
MTOR inhibition in epilepsy: Rationale and clinical perspectives
Ostendorf, A. P. & Wong, M., Feb 2015, In: CNS drugs. 29, 2, p. 91-99 9 p.Research output: Contribution to journal › Article › peer-review
Open Access80 Scopus citations -
2014
Cortical interneurons join the mix in absence seizures
Wong, M., 2014, In: Epilepsy Currents. 14, 4, p. 215-217 3 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2013
Mammalian target of rapamycin (mTOR) pathways in neurological diseases
Wong, M., Mar 2013, In: Biomedical Journal. 36, 2, p. 40-50 11 p.Research output: Contribution to journal › Article › peer-review
Open Access147 Scopus citations -
Rapamycin Attenuates the Development of Posttraumatic Epilepsy in a Mouse Model of Traumatic Brain Injury
Guo, D., Zeng, L., Brody, D. L. & Wong, M., May 14 2013, In: PloS one. 8, 5, e64078.Research output: Contribution to journal › Article › peer-review
Open Access164 Scopus citations -
Shining light on epilepsy: Optical approaches for treating seizures
Wong, M., 2013, In: Epilepsy Currents. 13, 2, p. 95-96 2 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Vigabatrin Inhibits Seizures and mTOR Pathway Activation in a Mouse Model of Tuberous Sclerosis Complex
Zhang, B., McDaniel, S. S., Rensing, N. R. & Wong, M., Feb 20 2013, In: PloS one. 8, 2, e57445.Research output: Contribution to journal › Article › peer-review
Open Access107 Scopus citations -
2012
Acute intermittent porphyria: A diagnostic challenge
Anyaegbu, E., Goodman, M., Ahn, S. Y., Thangarajh, M., Wong, M. & Shinawi, M., Jul 2012, In: Journal of Child Neurology. 27, 7, p. 917-921 5 p.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Brief seizures cause dendritic injury
Guo, D., Arnspiger, S., Rensing, N. R. & Wong, M., Jan 2012, In: Neurobiology of Disease. 45, 1, p. 348-355 8 p.Research output: Contribution to journal › Article › peer-review
Open Access40 Scopus citations -
Mammalian target of rapamycin (mtor) inhibition: Potential for antiseizure, antiepileptogenic, and epileptostatic therapy
Ryther, R. C. C. & Wong, M., Aug 1 2012, In: Current neurology and neuroscience reports. 12, 4, p. 410-418 9 p.Research output: Contribution to journal › Article › peer-review
53 Scopus citations -
mTOR as a potential treatment target for epilepsy
Wong, M., Sep 2012, In: Future Neurology. 7, 5, p. 537-545 9 p.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
Pentylenetetrazole-induced seizures cause acute, but not chronic, mTOR pathway activation in rat
Zhang, B. & Wong, M., Mar 2012, In: Epilepsia. 53, 3, p. 506-511 6 p.Research output: Contribution to journal › Article › peer-review
Open Access78 Scopus citations -
Rapamycin has paradoxical effects on S6 phosphorylation in rats with and without seizures
Chen, L., Hu, L., Dong, J. Y., Ye, Q., Hua, N., Wong, M. & Zeng, L. H., Nov 2012, In: Epilepsia. 53, 11, p. 2026-2033 8 p.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
Tuberous sclerosis and epilepsy: Role of astrocytes
Wong, M. & Crino, P. B., Aug 2012, In: Glia. 60, 8, p. 1244-1250 7 p.Research output: Contribution to journal › Article › peer-review
Open Access40 Scopus citations -
2011
Enhanced epidermal growth factor, hepatocyte growth factor, and vascular endothelial growth factor expression in tuberous sclerosis complex
Parker, W. E., Orlova, K. A., Heuer, G. G., Baybis, M., Aronica, E., Frost, M., Wong, M. & Crino, P. B., Jan 2011, In: American Journal of Pathology. 178, 1, p. 296-305 10 p.Research output: Contribution to journal › Article › peer-review
Open Access32 Scopus citations -
Profile of ezogabine (retigabine) and its potential as an adjunctive treatment for patients with partial-onset seizures
Weisenberg, J. L. Z. & Wong, M., 2011, In: Neuropsychiatric Disease and Treatment. 7, 1, p. 409-414 6 p.Research output: Contribution to journal › Article › peer-review
28 Scopus citations -
The ketogenic diet inhibits the mammalian target of rapamycin (mTOR) pathway
McDaniel, S. S., Rensing, N. R., Thio, L. L., Yamada, K. A. & Wong, M., Mar 2011, In: Epilepsia. 52, 3, p. e7-e11Research output: Contribution to journal › Article › peer-review
Open Access226 Scopus citations -
Tsc2 gene inactivation causes a more severe epilepsy phenotype than Tsc1 inactivation in a mouse model of Tuberous Sclerosis Complex
Zeng, L. H., Rensing, N. R., Zhang, B., Gutmann, D. H., Gambello, M. J. & Wong, M., Feb 2011, In: Human molecular genetics. 20, 3, p. 445-454 10 p., ddq491.Research output: Contribution to journal › Article › peer-review
Open Access181 Scopus citations -
2010
Modulation of astrocyte glutamate transporters decreases seizures in a mouse model of Tuberous Sclerosis Complex
Zeng, L. H., Bero, A. W., Zhang, B., Holtzman, D. M. & Wong, M., Mar 2010, In: Neurobiology of Disease. 37, 3, p. 764-771 8 p.Research output: Contribution to journal › Article › peer-review
Open Access67 Scopus citations -
MTOR and epileptogenesis in developmental brain malformations
Wong, M. & Crino, P. B., Dec 2010, In: Epilepsia. 51, SUPPL. 5, p. 72 1 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
2009
FGF14 regulates the intrinsic excitability of cerebellar Purkinje neurons
Shakkottai, V. G., Xiao, M., Xu, L., Wong, M., Nerbonne, J. M., Ornitz, D. M. & Yamada, K. A., Jan 2009, In: Neurobiology of Disease. 33, 1, p. 81-88 8 p.Research output: Contribution to journal › Article › peer-review
Open Access104 Scopus citations -
Impaired astrocytic gap junction coupling and potassium buffering in a mouse model of tuberous sclerosis complex
Xu, L., Zeng, L. H. & Wong, M., May 2009, In: Neurobiology of Disease. 34, 2, p. 291-299 9 p.Research output: Contribution to journal › Article › peer-review
75 Scopus citations -
The mammalian target of rapamycin signaling pathway mediates epileptogenesis in a model of temporal lobe epilepsy
Zeng, L. H., Rensing, N. R. & Wong, M., May 27 2009, In: Journal of Neuroscience. 29, 21, p. 6964-6972 9 p.Research output: Contribution to journal › Article › peer-review
Open Access425 Scopus citations -
2008
Increased severity of pentylenetetrazol induced seizures in leptin deficient ob/ob mice
Erbayat-Altay, E., Yamada, K. A., Wong, M. & Thio, L. L., Mar 12 2008, In: Neuroscience Letters. 433, 2, p. 82-86 5 p.Research output: Contribution to journal › Article › peer-review
43 Scopus citations -
Leptin inhibits 4-aminopyridine- and pentylenetetrazole-induced seizures and AMPAR-mediated synaptic transmission in rodents
Xu, L., Rensing, N., Yang, X. F., Hai, X. Z., Liu, L. T., Rothman, S. M., Weisenfeld, A. E., Wong, M. & Yamada, K. A., Jan 2 2008, In: Journal of Clinical Investigation. 118, 1, p. 272-280 9 p.Research output: Contribution to journal › Article › peer-review
Open Access107 Scopus citations -
Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex
Zeng, L. H., Xu, L., Gutmann, D. H. & Wong, M., Apr 2008, In: Annals of neurology. 63, 4, p. 444-453 10 p.Research output: Contribution to journal › Article › peer-review
Open Access521 Scopus citations -
2007
Abnormal glutamate homeostasis and impaired synaptic plasticity and learning in a mouse model of tuberous sclerosis complex
Zeng, L. H., Ouyang, Y., Gazit, V., Cirrito, J. R., Jansen, L. A., Ess, K. C., Yamada, K. A., Wozniak, D. F., Holtzman, D. M., Gutmann, D. H. & Wong, M., Nov 2007, In: Neurobiology of Disease. 28, 2, p. 184-196 13 p.Research output: Contribution to journal › Article › peer-review
Open Access108 Scopus citations -
Hippocampal seizures cause depolymerization of filamentous actin in neurons independent of acute morphological changes
Ouyang, Y., Yang, X. F., Hu, X. Y., Erbayat-Altay, E., Zeng, L. H., Lee, J. M. & Wong, M., Apr 27 2007, In: Brain Research. 1143, 1, p. 238-246 9 p.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
Kainate seizures cause acute dendritic injury and actin depolymerization in vivo
Zeng, L. H., Xu, L., Rensing, N. R., Sinatra, P. M., Rothman, S. M. & Wong, M., Oct 24 2007, In: Journal of Neuroscience. 27, 43, p. 11604-11613 10 p.Research output: Contribution to journal › Article › peer-review
Open Access155 Scopus citations -
Successive neuron loss in the thalamus and cortex in a mouse model of infantile neuronal ceroid lipofuscinosis
Kielar, C., Maddox, L., Bible, E., Pontikis, C. C., Macauley, S. L., Griffey, M. A., Wong, M., Sands, M. S. & Cooper, J. D., Jan 2007, In: Neurobiology of Disease. 25, 1, p. 150-162 13 p.Research output: Contribution to journal › Article › peer-review
Open Access141 Scopus citations -
The natural history and treatment of epilepsy in a murine model of tuberous sclerosis
Erbayat-Altay, E., Zeng, L. H., Xu, L., Gutmann, D. H. & Wong, M., Aug 2007, In: Epilepsia. 48, 8, p. 1470-1476 7 p.Research output: Contribution to journal › Article › peer-review
Open Access53 Scopus citations -
2006
CNS-directed AAV2-mediated gene therapy ameliorates functional deficits in a murine model of infantile neuronal ceroid lipofuscinosis
Griffey, M. A., Wozniak, D., Wong, M., Bible, E., Johnson, K., Rothman, S. M., Wentz, A. E., Cooper, J. D. & Sands, M. S., Mar 2006, In: Molecular Therapy. 13, 3, p. 538-547 10 p.Research output: Contribution to journal › Article › peer-review
Open Access112 Scopus citations -
2005
Epileptogenesis and reduced inward rectifier potassium current in tuberous sclerosis complex-1-deficient astrocytes
Jansen, L. A., Uhlmann, E. J., Crino, P. B., Gutmann, D. H. & Wong, M., Dec 2005, In: Epilepsia. 46, 12, p. 1871-1880 10 p.Research output: Contribution to journal › Article › peer-review
Open Access105 Scopus citations -
In vivo imaging of dendritic spines during electrographic seizures
Rensing, N., Ouyang, Y., Yang, X. F., Yamada, K. A., Rothman, S. M. & Wong, M., Dec 2005, In: Annals of neurology. 58, 6, p. 888-898 11 p.Research output: Contribution to journal › Article › peer-review
Open Access51 Scopus citations -
Transient decrease in F-actin may be necessary for translocation of proteins into dendritic spines
Ouyang, Y., Wong, M., Capani, F., Rensing, N., Lee, C. S., Liu, Q., Neusch, C., Martone, M. E., Wu, J. Y., Yamada, K., Ellisman, M. H. & Choi, D. W., Dec 2005, In: European Journal of Neuroscience. 22, 12, p. 2995-3005 11 p.Research output: Contribution to journal › Article › peer-review
Open Access72 Scopus citations -
2003
An animal model of generalized nonconvulsive status epilepticus: Immediate characteristics and long-term effects
Wong, M., Wozniak, D. F. & Yamada, K. A., Sep 1 2003, In: Experimental Neurology. 183, 1, p. 87-99 13 p.Research output: Contribution to journal › Article › peer-review
44 Scopus citations -
Impaired glial glutamate transport in a mouse tuberous sclerosis epilepsy model
Wong, M., Ess, K. C., Uhlmann, E. J., Jansen, L. A., Li, W., Crino, P. B., Mennerick, S., Yamada, K. A. & Gutmann, D. H., Aug 1 2003, In: Annals of neurology. 54, 2, p. 251-256 6 p.Research output: Contribution to journal › Article › peer-review
165 Scopus citations -
2002
Astrocyte-specific TSC1 conditional knockout mice exhibit abnormal neuronal organization and seizures
Uhlmann, E. J., Wong, M., Baldwin, R. L., Bajenaru, M. L., Onda, H., Kwiatkowski, D. J., Yamada, K. & Gutmann, D. H., Sep 2002, In: Annals of neurology. 52, 3, p. 285-296 12 p.Research output: Contribution to journal › Article › peer-review
299 Scopus citations -
Ataxia and paroxysmal dyskinesia in mice lacking axonally transported FGF14
Wang, Q., Bardgett, M. E., Wong, M., Wozniak, D. F., Lou, J., McNeil, B. D., Chen, C., Nardi, A., Reid, D. C., Yamada, K. & Ornitz, D. M., Jul 3 2002, In: Neuron. 35, 1, p. 25-38 14 p.Research output: Contribution to journal › Article › peer-review
Open Access163 Scopus citations -
Cerebrospinal fluid neuron-specific enolase following seizures in children: Role of etiology
Wong, M., Ess, K. & Landt, M., 2002, In: Journal of Child Neurology. 17, 4, p. 261-264 4 p.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
2001
Developmental characteristics of epileptiform activity in immature rat neocortex: A comparison of four in vitro seizure models
Wong, M. & Yamada, K. A., Jun 29 2001, In: Developmental Brain Research. 128, 2, p. 113-120 8 p.Research output: Contribution to journal › Article › peer-review
47 Scopus citations -
Postictal cerebrospinal fluid abnormalities in children
Wong, M., Schlaggar, B. L. & Landt, M., 2001, In: Journal of Pediatrics. 138, 3, p. 373-377 5 p.Research output: Contribution to journal › Article › peer-review
25 Scopus citations -
2000
Cerebrospinal fluid protein concentration in pediatric patients: Defining clinically relevant reference values
Wong, M., Schlaggar, B. L., Buller, R. S., Storch, G. A. & Landt, M., 2000, In: Archives of Pediatrics and Adolescent Medicine. 154, 8, p. 827-831 5 p.Research output: Contribution to journal › Article › peer-review
56 Scopus citations -
Cyclosporine induces epileptiform activity in an in vitro seizure model
Wong, M. & Yamada, K. A., 2000, In: Epilepsia. 41, 3, p. 271-276 6 p.Research output: Contribution to journal › Article › peer-review
Open Access26 Scopus citations -
Ketone bodies do not directly alter excitatory or inhibitory hippocampal synaptic transmission
Thio, L. L., Wong, M. & Yamada, K. A., Jan 25 2000, In: Neurology. 54, 2, p. 325-331 7 p.Research output: Contribution to journal › Article › peer-review
129 Scopus citations -
Leptin in cerebrospinal fluid from children: Correlation with plasma leptin, sexual dimorphism, and lack of protein binding
Landt, M., Parvin, C. A. & Wong, M., 2000, In: Clinical chemistry. 46, 6, p. 854-858 5 p.Research output: Contribution to journal › Article › peer-review
Open Access31 Scopus citations -
Motor benefit from levodopa in spastic quadriplegic cerebral palsy
Brunstrom, J. E., Bastian, A. J., Wong, M. & Mink, J. W., 2000, In: Annals of neurology. 47, 5, p. 662-665 4 p.Research output: Contribution to journal › Article › peer-review
29 Scopus citations