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Michael Whyte

Professor of Medicine, Professor of Pediatrics, Professor of Genetics

    • 18358 Citations
    1969 …2020

    Research output per year

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    Personal profile

    Research interests

    Heritable disorders of bone and mineral metabolism - including diagnosis, natural history, and treatment. Dysplastic skeletal diseases - including high bone mass, accelerated bone turnover, and osteolytic skeletal disease. Physiological role of alkaline phosphatase, osteoprotegerin, and RANK-Ligand action in bone biology.

    Areas of Clinical Interest

    Diagnosis and treatment of heritable disorders of bone and mineral metabolism, bone disease in adults and children, mineral disease, osteogenesis imperfecta, rickets, osteopetrosis, hypophosphatasia, hypophosphatemia, genetics, vitamin D-resistant rickets, metabolic and dysplastic bone disease in children, chondrodysplasia, pseudohypoparathyroidism, juvenile osteoporosis

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    Research Output

    Bruck syndrome 2 variant lacking congenital contractures and involving a novel compound heterozygous PLOD2 mutation

    Mumm, S., Gottesman, G. S., Wenkert, D., Campeau, P. M., Nenninger, A., Huskey, M., Bijanki, V. N., Veis, D. J., Barnes, A. M., Marini, J. C., Stolina, M., Zhang, F., McAlister, W. H. & Whyte, M. P., Jan 2020, In : Bone. 130, 115047.

    Research output: Contribution to journal › Article

    • 1 Scopus citations

    Early-onset Paget's disease of bone in a Mexican family caused by a novel tandem duplication (77dup27) in TNFRSF11A that encodes RANK

    Iwamoto, S. J., Rothman, M. S., Duan, S., Baker, J. C., Mumm, S. & Whyte, M. P., Apr 2020, In : Bone. 133, 115224.

    Research output: Contribution to journal › Article

    • 1 Scopus citations

    Growth Curves for Children with X-linked Hypophosphatemia

    Mao, M., Carpenter, T. O., Whyte, M. P., Skrinar, A., Chen, C. Y., San Martin, J. & Rogol, A. D., Oct 1 2020, In : The Journal of clinical endocrinology and metabolism. 105, 10

    Research output: Contribution to journal › Article

    Open Access

    • Healing of vitamin D deficiency rickets complicating hypophosphatasia suggests a role beyond circulating mineral sufficiency for vitamin D in musculoskeletal health

    Lin, E. L., Gottesman, G. S., McAlister, W. H., Bijanki, V. N., Mack, K. E., Griffin, D. M., Mumm, S. & Whyte, M. P., Jul 2020, In : Bone. 136, 115322.

    Research output: Contribution to journal › Article

    • 2 Scopus citations

    High bone mass from mutation of low-density lipoprotein receptor-related protein 6 (LRP6)

    Brance, M. L., Brun, L. R., Cóccaro, N. M., Aravena, A., Duan, S., Mumm, S. & Whyte, M. P., Dec 2020, In : Bone. 141, 115550.

    Research output: Contribution to journal › Article