• 3779
    Citations
1984 …2024

Research activity per year

Personal profile

Research interests

We study the genetic and biochemical mechanisms that regulate nephron progenitor cells, and how these developmental pathways are used for repair and regeneration of the injured kidney. We use whole exome sequencing and functional assays in zebrafish to identify novel genetic causes of human kidney birth defects.

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  • PhD/MSTP Students

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  • Heterogeneous associations between interleukin-6 receptor variants and phenotypes across ancestries and implications for therapy

    Wang, X., Liu, M., Nogues, I. E., Chen, T., Xiong, X., Bonzel, C. L., Zhang, H., Hong, C., Xia, Y., Dahal, K., Costa, L., Cui, J., Gaziano, J. M., Kim, S. C., Ho, Y. L., Cho, K., Cai, T., Liao, K. P., Muralidhar, S. & Moser, J. & 95 others, Deen, J. E., Tsao, P. S., Muralidhar, S., Gaziano, J. M., Hauser, E., Kilbourne, A., Luoh, S. W., Matheny, M., Oslin, D., Gaziano, J. M., Tsao, P. S., Churby, L., Whitbourne, S. B., Brewer, J. V., Shayan, S., Selva, L. E., Pyarajan, S., Cho, K., DuVall, S. L., Brophy, M. T., Gaziano, J. M., Tsao, P. S., Stephens, B., Connor, T., Assimes, T. L., Hung, A., Kranzler, H., Aguayo, S., Ahuja, S., Alexander, K., Androulakis, X. M., Balasubramanian, P., Ballas, Z., Beckham, J., Bhushan, S., Boyko, E., Cohen, D., Dellitalia, L., Faulk, L. C., Fayad, J., Fujii, D., Gappy, S., Gesek, F., Greco, J., Godschalk, M., Gress, T. W., Gupta, S., Gutierrez, S., Harley, J., Hammer, K., Hamner, M., Hung, A., Hurley, R., Iruvanti, P., Jacono, F., Jhala, D., Kinlay, S., Klein, J., Landry, M., Liang, P., Liangpunsakul, S., Lichy, J., Mahan, C. S., Marrache, R., Mastorides, S., Mates, E., Mattocks, K., Meyer, P., Moorman, J., Morgan, T., Murdoch, M., Norton, J., Okusaga, O., Oursler, K. A., Palacio, A., Poon, S., Potter, E., Rauchman, M., Servatius, R., Sharma, S., Smith, R., Sriram, P., Strollo, P., Tandon, N., Tsao, P., Villareal, G., Wallbom, A., Walsh, J., Wells, J., Whittle, J., Whooley, M., Williams, A. E., Wilson, P., Xu, J. & Yeh, S. S., Dec 2024, In: Scientific reports. 14, 1, 8021.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • The chromatin landscape of healthy and injured cell types in the human kidney

    Gisch, D. L., Brennan, M., Lake, B. B., Basta, J., Keller, M. S., Melo Ferreira, R., Akilesh, S., Ghag, R., Lu, C., Cheng, Y. H., Collins, K. S., Parikh, S. V., Rovin, B. H., Robbins, L., Stout, L., Conklin, K. Y., Diep, D., Zhang, B., Knoten, A. & Barwinska, D. & 333 others, Asghari, M., Sabo, A. R., Ferkowicz, M. J., Sutton, T. A., Kelly, K. J., De Boer, I. H., Rosas, S. E., Kiryluk, K., Hodgin, J. B., Alakwaa, F., Winfree, S., Jefferson, N., Türkmen, A., Gaut, J. P., Gehlenborg, N., Phillips, C. L., El-Achkar, T. M., Dagher, P. C., Hato, T., Zhang, K., Himmelfarb, J., Kretzler, M., Mollah, S., Lake, B., Morales, A., Stillman, I., Lecker, S., Bogen, S., Verma, A., Yu, G., Schmidt, I., Henderson, J., Beck, L., Yadati, P., Waikar, S., Amodu, A. A., Maikhor, S., Ilori, T., Colona, M. R., Weins, A., McMahon, G., Hacohen, N., Greka, A., Marshall, J. L., Hoover, P. J., Viswanathan, V. S., Crawford, D., Aulisio, M., Bush, W., Chen, Y., Madabhushi, A., O’Malley, C., Gadegbeku, C., Sendrey, D., Poggio, E., O’Toole, J., Sedor, J., Taliercio, J., Bush, L., Herlitz, L., Palmer, E., Nguyen, J., Spates-Harden, K., Cooperman, L., Jolly, S., Vinovskis, C., Bomback, A., Barasch, J., Kiryluk, K., Appelbaum, P., D’Agati, V., Berrouet, C., Mehl, K., Sabatello, M., Shang, N., Balderes, O., Canetta, P. A., Kudose, S., de Pinho Gonçalves, J., Migas, L., Van de Plas, R., Lardenoije, R., Barisoni, L., Rennke, H., Verdoes, A., Sabo, A., Gisch, D. L., Williams, J., Kelly, K., Dunn, K., Eadon, M., Ferkowicz, M., Dagher, P., Winfree, S., Bledsoe, S., Wofford, S., (El-Achkar), T. A., Sutton, T., Bowen, W., Slade, A., Record, E., Cheng, Y., Jain, Y., Herr, B., Quardokus, E., Wang, A., Villalobos, C. P. C., Parikh, C., Atta, M., Menez, S., Wen, Y., Xu, A., Bernard, L., Johansen, C., Chen, S., Rosas, S., Donohoe, I., Sun, J., Knight, R., Shpigel, A., Bebiak, J., Saul, J., Ardayfio, J., Koewler, R., Pinkeney, R., Campbell, T., Azeloglu, E., Nadkarni, G., He, J., Tokita, J., Campbell, K., Patel, M., Lefferts, S., Iyengar, S. R., Ward, S., Coca, S., He, C., Xiong, Y., Prasad, P., Rovin, B., Shapiro, J. P., Parikh, S., Madhavan, S. M., Lukowski, J., Velickovic, D., Pasa-Tolic, L., Oliver, G., Troyanskaya, O., Sealfon, R., Mao, W., Wong, A., Pollack, A., Goltsev, Y., Ginley, B., Lutnick, B., Nolan, G., Anjani, K., Mukatash, T., Laszik, Z. G., Campos, B., Thajudeen, B., Beyda, D., Bracamonte, E., Brosius, F., Woodhead, G., Mendoza, K., Marquez, N., Scott, R., Tsosie, R., Saunders, M., Rike, A., Woodle, E. S., Lee, P. J., Alloway, R. R., Shi, T., Hsieh, E., Kendrick, J., Thurman, J., Wrobel, J., Pyle, L., Bjornstad, P., Lucarelli, N., Sarder, P., Renteria, A., Ricardo, A., Srivastava, A., Redmond, D., Carmona-Powell, E., Bui, J., Lash, J., Fox, M., Meza, N., Gaba, R., Setty, S., Kelly, T., Lienczewski, C., Demeke, D., Otto, E., Ascani, H., Hodgin, J., Schaub, J., Hartman, J., Mariani, L., Bitzer, M., Rose, M., Bonevich, N., Conser, N., McCown, P., Dull, R., Menon, R., Reamy, R., Eddy, S., Balis, U., Blanc, V., Nair, V., He, Y. O., Wright, Z., Steck, B., Luo, J., Frey, R., Coleman, A., Henderson-Brown, D., Berge, J., Caramori, M. L., Adeyi, O., Nachman, P., Safadi, S., Flanagan, S., Ma, S., Klett, S., Wolf, S., Harindhanavudhi, T., Rao, V., Mottl, A., Froment, A., Zeitler, E., Bream, P., Kelley, S., Rosengart, M., Elder, M., Palevsky, P., Murugan, R., Hall, D. E., Bender, F., Winters, J., Kellum, J. A., Gilliam, M., Tublin, M., Tan, R., Zhang, G., Sharma, K., Venkatachalam, M., Hendricks, A., Kermani, A., Torrealba, J., Vazquez, M., Wang, N., Cai, Q., Miller, R. T., Ma, S., Hedayati, S., Hoofnagle, A., Wangperawong, A., Berglund, A., Dighe, A. L., Young, B., Larson, B., Berry, B., Alpers, C., Limonte, C., Stutzke, C., Roberts, G., de Boer, I., Snyder, J., Phuong, J., Carson, J., Rezaei, K., Tuttle, K., Brown, K., Blank, K., Sarkisova, N., Jefferson, N., McClelland, R., Mooney, S., Nam, Y., Wilcox, A., Park, C., Dowd, F., Williams, K., Grewenow, S. M., Daniel, S., Shankland, S., Pamreddy, A., Ye, H., Montellano, R., Bansal, S., Pillai, A., Zhang, D., Park, H., Patel, J., Sambandam, K., Basit, M., Wen, N., Moe, O. W., Toto, R. D., Lee, S. C., Sharman, K., Caprioli, R. M., Fogo, A., Allen, J., Spraggins, J., Djambazova, K., de Caestecker, M., Dufresne, M., Farrow, M., Vijayan, A., Minor, B., Nwanne, G., Gaut, J., Conlon, K., Kaushal, M., Diettman, S. M., Victoria Castro, A. M., Moledina, D., Wilson, F. P., Moeckel, G., Cantley, L., Shaw, M., Kakade, V., Arora, T., Jain, S., Rauchman, M. & Eadon, M. T., Dec 2024, In: Nature communications. 15, 1, 433.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    7 Scopus citations
  • 3 Scopus citations
  • Open Access
    32 Scopus citations
  • A user-friendly tool for cloud-based whole slide image segmentation with examples from renal histopathology

    the Kidney Precision Medicine Project, Lutnick, B., Manthey, D., Becker, J. U., Ginley, B., Moos, K., Zuckerman, J. E., Rodrigues, L., Gallan, A. J., Barisoni, L., Alpers, C. E., Wang, X. X., Myakala, K., Jones, B. A., Levi, M., Kopp, J. B., Yoshida, T., Zee, J., Han, S. S. & Jain, S. & 181 others, Rosenberg, A. Z., Jen, K. Y., Sarder, P., Lutnick, B., Ginley, B., Knight, R., Lecker, S. H., Stillman, I., Bogen, S., Amodu, A. A., Ilori, T., Schmidt, I., Maikhor, S., Beck, L. H., Verma, A., Henderson, J. M., Onul, I., Waikar, S., McMahon, G. M., Weins, A., Colona, M. R., Valerius, M. T., Hacohen, N., Hoover, P. J., Greka, A., Marshall, J. L., Aulisio, M., Chen, Y. M., Janowczyk, A., Jayapandian, C., Viswanathan, V. S., Bush, W. S., Crawford, D. C., Madabhushi, A., O’toole, J., Poggio, E., Sedor, J., Cooperman, L., Jolly, S., Herlitz, L., Nguyen, J., Gonzalez-Vicente, A., Palmer, E., Sendrey, D., Taliercio, J., Bush, L., Spates-Harden, K., Vinovskis, C., Bjornstad, P. M., Pyle, L., Appelbaum, P., Barasch, J. M., Bomback, A. S., D’Agati, V. D., Kiryluk, K., Mehl, K., Canetta, P. A., Shang, N., Balderes, O., Kudose, S., Alexandrov, T., Rennke, H., El-Achkar, T. M., Cheng, Y., Dagher, P. C., Eadon, M. T., Dunn, K. W., Kelly, K. J., Sutton, T. A., Barwinska, D., Ferkowicz, M. J., Winfree, S., Bledsoe, S., Rivera, M., Williams, J. C., Ferreira, R. M., Borner, K., Bueckle, A., Herr, B. W., Quardokus, E. M., Record, E., Su, J., Gisch, D., Wofford, S., Jain, Y., Parikh, C. R., Corona-Villalobos, C. P., Menez, S., Wen, Y., Johansen, C., Rosas, S. E., Roy, N., Williams, M., Sun, J., Ardayfio, J., Bebiak, J., Brown, K., Campbell, C. E., Saul, J., Shpigel, A., Stutzke, C., Koewler, R., Campbell, T., Hayashi, L., Jefferson, N., Roberts, G. V., Pinkeney, R., Azeloglu, E. U., He, C., Iyengar, R., Hansen, J., Xiong, Y., Prasad, P., Srivastava, A., Rovin, B., Parikh, S., Shapiro, J. P., Madhavan, S. M., Anderton, C. R., Pasa-Tolic, L., Velickovic, D., Lukowski, J., Oliver, G. H., Troyanskaya, O., Sealfon, R., Wong, A., Tuttle, K. R., Pollack, A., Goltsev, Y., Zhang, K., Lake, B. B., Laszik, Z. G., Nolan, G., Boada, P., Sarwal, M., Anjani, K., Sigdel, T., Mukatash, T., Lee, P. J., Alloway, R. R., Woodle, E. S., Burg, A. R., Rike, A., Shi, T., Ascani, H., Balis, U. G. J., Hodgin, J. B., Kretzler, M., Lienczewski, C., Mariani, L. H., Menon, R., Steck, B., He, Y., Otto, E., Schaub, J., Blanc, V. M., Eddy, S., Conser, N. C., Luo, J., Frey, R., Palevsky, P. M., Rosengart, M., Kellum, J. A., Hall, D. E., Randhawa, P., Tublin, M., Murugan, R., Elder, M. M., Winters, J., Vita, T., Bender, F., Tan, R., Gilliam, M., Blank, K. N., Carson, J., De Boer, I. H., Dighe, A. L., Shankland, S., Vijayan, A., Gaut, J. P. & Rauchman, M. I., Dec 2022, In: Communications Medicine. 2, 1, 105.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    17 Scopus citations