Search results

  • 2019

    Erratum: Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology (The American Journal of Human Genetics (2019) 105(1) (15–28), (S0002929719301880), (10.1016/j.ajhg.2019.05.002))

    Spracklen, C. N., Karaderi, T., Yaghootkar, H., Schurmann, C., Fine, R. S., Kutalik, Z., Preuss, M. H., Lu, Y., Wittemans, L. B. L., Adair, L. S., Allison, M., Amin, N., Auer, P. L., Bartz, T. M., Blüher, M., Boehnke, M., Borja, J. B., Bork-Jensen, J., Broer, L., Chasman, D. I., & 84 othersChen, Y. D. I., Chirstofidou, P., Demirkan, A., van Duijn, C. M., Feitosa, M. F., Garcia, M. E., Graff, M., Grallert, H., Grarup, N., Guo, X., Haesser, J., Hansen, T., Harris, T. B., Highland, H. M., Hong, J., Ikram, M. A., Ingelsson, E., Jackson, R., Jousilahti, P., Kähönen, M., Kizer, J. R., Kovacs, P., Kriebel, J., Laakso, M., Lange, L. A., Lehtimäki, T., Li, J., Li-Gao, R., Lind, L., Luan, J., Lyytikäinen, L. P., MacGregor, S., Mackey, D. A., Mahajan, A., Mangino, M., Männistö, S., McCarthy, M. I., McKnight, B., Medina-Gomez, C., Meigs, J. B., Molnos, S., Mook-Kanamori, D., Morris, A. P., de Mutsert, R., Nalls, M. A., Nedeljkovic, I., North, K. E., Pennell, C. E., Pradhan, A. D., Province, M. A., Raitakari, O. T., Raulerson, C. K., Reiner, A. P., Ridker, P. M., Ripatti, S., Roberston, N., Rotter, J. I., Salomaa, V., Sandoval-Zárate, A. A., Sitlani, C. M., Spector, T. D., Strauch, K., Stumvoll, M., Taylor, K. D., Thuesen, B., Tönjes, A., Uitterlinden, A. G., Venturini, C., Walker, M., Wang, C. A., Wang, S., Wareham, N. J., Willems, S. M., Willems van Dijk, K., Wilson, J. G., Wu, Y., Yao, J., Young, K. L., Langenberg, C., Frayling, T. M., Kilpeläinen, T. O., Lindgren, C. M., Loos, R. J. F. & Mohlke, K. L., Sep 5 2019, In: American journal of human genetics. 105, 3, p. 670-671 2 p.

    Research output: Contribution to journalComment/debate

    Open Access
    3 Scopus citations
  • Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology

    Spracklen, C. N., Karaderi, T., Yaghootkar, H., Schurmann, C., Fine, R. S., Kutalik, Z., Preuss, M. H., Lu, Y., Wittemans, L. B. L., Adair, L. S., Allison, M., Amin, N., Auer, P. L., Bartz, T. M., Blüher, M., Boehnke, M., Borja, J. B., Bork-Jensen, J., Broer, L., Chasman, D. I., & 84 othersChen, Y. D. I., Chirstofidou, P., Demirkan, A., van Duijn, C. M., Feitosa, M. F., Garcia, M. E., Graff, M., Grallert, H., Grarup, N., Guo, X., Haesser, J., Hansen, T., Harris, T. B., Highland, H. M., Hong, J., Ikram, M. A., Ingelsson, E., Jackson, R., Jousilahti, P., Kähönen, M., Kizer, J. R., Kovacs, P., Kriebel, J., Laakso, M., Lange, L. A., Lehtimäki, T., Li, J., Li-Gao, R., Lind, L., Luan, J., Lyytikäinen, L. P., MacGregor, S., Mackey, D. A., Mahajan, A., Mangino, M., Männistö, S., McCarthy, M. I., McKnight, B., Medina-Gomez, C., Meigs, J. B., Molnos, S., Mook-Kanamori, D., Morris, A. P., de Mutsert, R., Nalls, M. A., Nedeljkovic, I., North, K. E., Pennell, C. E., Pradhan, A. D., Province, M. A., Raitakari, O. T., Raulerson, C. K., Reiner, A. P., Ridker, P. M., Ripatti, S., Roberston, N., Rotter, J. I., Salomaa, V., Sandoval-Zárate, A. A., Sitlani, C. M., Spector, T. D., Strauch, K., Stumvoll, M., Taylor, K. D., Thuesen, B., Tönjes, A., Uitterlinden, A. G., Venturini, C., Walker, M., Wang, C. A., Wang, S., Wareham, N. J., Willems, S. M., Willems van Dijk, K., Wilson, J. G., Wu, Y., Yao, J., Young, K. L., Langenberg, C., Frayling, T. M., Kilpeläinen, T. O., Lindgren, C. M., Loos, R. J. F. & Mohlke, K. L., Jul 3 2019, In: American journal of human genetics. 105, 1, p. 15-28 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    17 Scopus citations
  • Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

    23and Me Research Team, eQTLgen Consortium, International Cannabis Consortium & Social Science Genetic Association Consortium, Feb 1 2019, In: Nature Genetics. 51, 2, p. 245-257 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    364 Scopus citations
  • Genome-wide linkage analysis of carotid artery traits in exceptionally long-lived families

    for the Long Life Family Study, Dec 2019, In: Atherosclerosis. 291, p. 19-26 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    4 Scopus citations
  • Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium

    Merino, J., Dashti, H. S., Li, S. X., Sarnowski, C., Justice, A. E., Graff, M., Papoutsakis, C., Smith, C. E., Dedoussis, G. V., Lemaitre, R. N., Wojczynski, M. K., Männistö, S., Ngwa, J. S., Kho, M., Ahluwalia, T. S., Pervjakova, N., Houston, D. K., Bouchard, C., Huang, T., Orho-Melander, M., & 86 othersFrazier-Wood, A. C., Mook-Kanamori, D. O., Pérusse, L., Pennell, C. E., de Vries, P. S., Voortman, T., Li, O., Kanoni, S., Rose, L. M., Lehtimäki, T., Zhao, J. H., Feitosa, M. F., Luan, J., McKeown, N. M., Smith, J. A., Hansen, T., Eklund, N., Nalls, M. A., Rankinen, T., Huang, J., Hernandez, D. G., Schulz, C. A., Manichaikul, A., Li-Gao, R., Vohl, M. C., Wang, C. A., van Rooij, F. J. A., Shin, J., Kalafati, I. P., Day, F., Ridker, P. M., Kähönen, M., Siscovick, D. S., Langenberg, C., Zhao, W., Astrup, A., Knekt, P., Garcia, M., Rao, D. C., Qi, Q., Ferrucci, L., Ericson, U., Blangero, J., Hofman, A., Pausova, Z., Mikkilä, V., Wareham, N. J., Kardia, S. L. R., Pedersen, O., Jula, A., Curran, J. E., Zillikens, M. C., Viikari, J. S., Forouhi, N. G., Ordovás, J. M., Lieske, J. C., Rissanen, H., Uitterlinden, A. G., Raitakari, O. T., Kiefte-de Jong, J. C., Dupuis, J., Rotter, J. I., North, K. E., Scott, R. A., Province, M. A., Perola, M., Cupples, L. A., Turner, S. T., Sørensen, T. I. A., Salomaa, V., Liu, Y., Sung, Y. J., Qi, L., Bandinelli, S., Rich, S. S., de Mutsert, R., Tremblay, A., Oddy, W. H., Franco, O. H., Paus, T., Florez, J. C., Deloukas, P., Lyytikäinen, L. P., Chasman, D. I., Chu, A. Y. & Tanaka, T., Dec 1 2019, In: Molecular Psychiatry. 24, 12, p. 1920-1932 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    40 Scopus citations
  • Insulin Resistance Exacerbates Genetic Predisposition to Nonalcoholic Fatty Liver Disease in Individuals Without Diabetes

    Barata, L., Feitosa, M. F., Bielak, L. F., Halligan, B., Baldridge, A. S., Guo, X., Yerges-Armstrong, L. M., Smith, A. V., Yao, J., Palmer, N. D., VanWagner, L. B., Carr, J. J., Chen, Y. D. I., Allison, M., Budoff, M. J., Handelman, S. K., Kardia, S. L. R., Mosley, T. H., Ryan, K., Harris, T. B., & 10 othersLauner, L. J., Gudnason, V., Rotter, J. I., Fornage, M., Rasmussen-Torvik, L. J., Borecki, I. B., O’Connell, J. R., Peyser, P. A., Speliotes, E. K. & Province, M. A., Jul 2019, In: Hepatology Communications. 3, 7, p. 894-907 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    40 Scopus citations
  • Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions

    De Vries, P. S., Brown, M. R., Bentley, A. R., Sung, Y. J., Winkler, T. W., Ntalla, I., Schwander, K., Kraja, A. T., Guo, X., Franceschini, N., Cheng, C. Y., Sim, X., Vojinovic, D., Huffman, J. E., Musani, S. K., Li, C., Feitosa, M. F., Richard, M. A., Noordam, R., Aschard, H., & 246 othersBartz, T. M., Bielak, L. F., Deng, X., Dorajoo, R., Lohman, K. K., Manning, A. K., Rankinen, T., Smith, A. V., Tajuddin, S. M., Evangelou, E., Graff, M., Alver, M., Boissel, M., Chai, J. F., Chen, X., Divers, J., Gandin, I., Gao, C., Goel, A., Hagemeijer, Y., Harris, S. E., Hartwig, F. P., He, M., Horimoto, A. R. V. R., Hsu, F. C., Jackson, A. U., Kasturiratne, A., Komulainen, P., Kühnel, B., Laguzzi, F., Lee, J. H., Luan, JA., Lyytikäinen, L. P., Matoba, N., Nolte, I. M., Pietzner, M., Riaz, M., Said, M. A., Scott, R. A., Sofer, T., Stančáková, A., Takeuchi, F., Tayo, B. O., Van Der Most, P. J., Varga, T. V., Wang, Y., Ware, E. B., Wen, W., Yanek, L. R., Zhang, W., Zhao, J. H., Afaq, S., Amin, N., Amini, M., Arking, D. E., Aung, T., Ballantyne, C., Boerwinkle, E., Broeckel, U., Campbell, A., Canouil, M., Charumathi, S., Chen, Y. D. I., Connell, J. M., De Faire, U., De Las Fuentes, L., De Mutsert, R., De Silva, H. J., Ding, J., Dominiczak, A. F., Duan, Q., Eaton, C. B., Eppinga, R. N., Faul, J. D., Fisher, V., Forrester, T., Franco, O. H., Friedlander, Y., Ghanbari, M., Giulianini, F., Grabe, H. J., Grove, M. L., Gu, C. C., Harris, T. B., Heikkinen, S., Heng, C. K., Hirata, M., Hixson, J. E., Howard, B. V., Ikram, M. A., Jacobs, D. R., Johnson, C., Jonas, J. B., Kammerer, C. M., Katsuya, T., Khor, C. C., Kilpeläinen, T. O., Koh, W. P., Koistinen, H. A., Kolcic, I., Kooperberg, C., Krieger, J. E., Kritchevsky, S. B., Kubo, M., Kuusisto, J., Lakka, T. A., Langefeld, C. D., Langenberg, C., Launer, L. J., Lehne, B., Lemaitre, R. N., Li, Y., Liang, J., Liu, J., Liu, K., Loh, M., Louie, T., Mägi, R., Manichaikul, A. W., McKenzie, C. A., Meitinger, T., Metspalu, A., Milaneschi, Y., Milani, L., Mohlke, K. L., Mosley, T. H., Mukamal, K. J., Nalls, M. A., Nauck, M., Nelson, C. P., Sotoodehnia, N., O'Connell, J. R., Palmer, N. D., Pazoki, R., Pedersen, N. L., Peters, A., Peyser, P. A., Polasek, O., Poulter, N., Raffel, L. J., Raitakari, O. T., Reiner, A. P., Rice, T. K., Rich, S. S., Robino, A., Robinson, J. G., Rose, L. M., Rudan, I., Schmidt, C. O., Schreiner, P. J., Scott, W. R., Sever, P., Shi, Y., Sidney, S., Sims, M., Smith, B. H., Smith, J. A., Snieder, H., Starr, J. M., Strauch, K., Tan, N., Taylor, K. D., Teo, Y. Y., Tham, Y. C., Uitterlinden, A. G., Van Heemst, D., Vuckovic, D., Waldenberger, M., Wang, L., Wang, Y., Wang, Z., Wei, W. B., Williams, C., Wilson, G., Wojczynski, M. K., Yao, J., Yu, B., Yu, C., Yuan, J. M., Zhao, W., Zonderman, A. B., Becker, D. M., Boehnke, M., Bowden, D. W., Chambers, J. C., Deary, I. J., Esko, T., Farrall, M., Franks, P. W., Freedman, B. I., Froguel, P., Gasparini, P., Gieger, C., Horta, B. L., Kamatani, Y., Kato, N., Kooner, J. S., Laakso, M., Leander, K., Lehtimäki, T., Magnusson, P. K. E., Penninx, B., Pereira, A. C., Rauramaa, R., Samani, N. J., Scott, J., Shu, X. O., Van Der Harst, P., Wagenknecht, L. E., Wang, Y. X., Wareham, N. J., Watkins, H., Weir, D. R., Wickremasinghe, A. R., Zheng, W., Elliott, P., North, K. E., Bouchard, C., Evans, M. K., Gudnason, V., Liu, C. T., Liu, Y., Psaty, B. M., Ridker, P. M., Van Dam, R. M., Kardia, S. L. R., Zhu, X., Rotimi, C. N., Mook-Kanamori, D. O., Fornage, M., Kelly, T. N., Fox, E. R., Hayward, C., Van Duijn, C. M., Tai, E. S., Wong, T. Y., Liu, J., Rotter, J. I., Gauderman, W. J., Province, M. A., Munroe, P. B., Rice, K., Chasman, D. I., Cupples, L. A., Rao, D. C. & Morrison, A. C., Jun 1 2019, In: American journal of epidemiology. 188, 6, p. 1033-1054 22 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    65 Scopus citations
  • Multi-ancestry genome-wide gene–smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

    Understanding Society Scientific group, Lifelines Cohort, COGENT-Kidney Consortium & EPIC-InterAct Consortium, Apr 1 2019, In: Nature Genetics. 51, 4, p. 636-648 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    75 Scopus citations
  • Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration

    Noordam, R., Bos, M. M., Wang, H., Winkler, T. W., Bentley, A. R., Kilpeläinen, T. O., de Vries, P. S., Sung, Y. J., Schwander, K., Cade, B. E., Manning, A., Aschard, H., Brown, M. R., Chen, H., Franceschini, N., Musani, S. K., Richard, M., Vojinovic, D., Aslibekyan, S., Bartz, T. M., & 128 othersde las Fuentes, L., Feitosa, M., Horimoto, A. R., Ilkov, M., Kho, M., Kraja, A., Li, C., Lim, E., Liu, Y., Mook-Kanamori, D. O., Rankinen, T., Tajuddin, S. M., van der Spek, A., Wang, Z., Marten, J., Laville, V., Alver, M., Evangelou, E., Graff, M. E., He, M., Kühnel, B., Lyytikäinen, L. P., Marques-Vidal, P., Nolte, I. M., Palmer, N. D., Rauramaa, R., Shu, X. O., Snieder, H., Weiss, S., Wen, W., Yanek, L. R., Adolfo, C., Ballantyne, C., Bielak, L., Biermasz, N. R., Boerwinkle, E., Dimou, N., Eiriksdottir, G., Gao, C., Gharib, S. A., Gottlieb, D. J., Haba-Rubio, J., Harris, T. B., Heikkinen, S., Heinzer, R., Hixson, J. E., Homuth, G., Ikram, M. A., Komulainen, P., Krieger, J. E., Lee, J., Liu, J., Lohman, K. K., Luik, A. I., Mägi, R., Martin, L. W., Meitinger, T., Metspalu, A., Milaneschi, Y., Nalls, M. A., O’Connell, J., Peters, A., Peyser, P., Raitakari, O. T., Reiner, A. P., Rensen, P. C. N., Rice, T. K., Rich, S. S., Roenneberg, T., Rotter, J. I., Schreiner, P. J., Shikany, J., Sidney, S. S., Sims, M., Sitlani, C. M., Sofer, T., Strauch, K., Swertz, M. A., Taylor, K. D., Uitterlinden, A. G., van Duijn, C. M., Völzke, H., Waldenberger, M., Wallance, R. B., van Dijk, K. W., Yu, C., Zonderman, A. B., Becker, D. M., Elliott, P., Esko, T., Gieger, C., Grabe, H. J., Lakka, T. A., Lehtimäki, T., North, K. E., Penninx, B. W. J. H., Vollenweider, P., Wagenknecht, L. E., Wu, T., Xiang, Y. B., Zheng, W., Arnett, D. K., Bouchard, C., Evans, M. K., Gudnason, V., Kardia, S., Kelly, T. N., Kritchevsky, S. B., Loos, R. J. F., Pereira, A. C., Province, M., Psaty, B. M., Rotimi, C., Zhu, X., Amin, N., Cupples, L. A., Fornage, M., Fox, E. F., Guo, X., Gauderman, W. J., Rice, K., Kooperberg, C., Munroe, P. B., Liu, C. T., Morrison, A. C., Rao, D. C., van Heemst, D. & Redline, S., Dec 1 2019, In: Nature communications. 10, 1, 5121.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    48 Scopus citations
  • Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity

    Lifelines Cohort Study, Dec 1 2019, In: Nature communications. 10, 1, 376.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    53 Scopus citations
  • 2018

    A high throughput, functional screen of human Body Mass Index GWAS loci using tissue-specific RNAi Drosophila melanogaster crosses

    Baranski, T. J., Kraja, A. T., Fink, J. L., Feitosa, M., Lenzini, P. A., Borecki, I. B., Liu, C. T., Cupples, L. A., North, K. E. & Province, M. A., Apr 2018, In: PLoS genetics. 14, 4, e1007222.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    21 Scopus citations
  • A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

    The CHARGE Neurology Working Group, The COGENT-Kidney Consortium, The GIANT Consortium & Lifelines Cohort Study, Mar 1 2018, In: American journal of human genetics. 102, 3, p. 375-400 26 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    92 Scopus citations
  • An exome-wide sequencing study of lipid response to high-fat meal and fenofibrate in Caucasians from the GOLDN cohort

    Geng, X., Irvin, M. R., Hidalgo, B., Aslibekyan, S., Srinivasasainagendra, V., An, P., Frazier-Wood, A. C., Tiwari, H. K., Dave, T., Ryan, K., Ordovas, J. M., Straka, R. J., Feitosa, M. F., Hopkins, P. N., Borecki, I., Province, M. A., Mitchell, B. D., Arnett, D. K. & Zhi, D., 2018, In: Journal of lipid research. 59, 4, p. 722-729 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    7 Scopus citations
  • Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and Tamoxifen Therapy

    Goetz, M. P., Sangkuhl, K., Guchelaar, H. J., Schwab, M., Province, M., Whirl-Carrillo, M., Symmans, W. F., McLeod, H. L., Ratain, M. J., Zembutsu, H., Gaedigk, A., van Schaik, R. H., Ingle, J. N., Caudle, K. E. & Klein, T. E., May 2018, In: Clinical pharmacology and therapeutics. 103, 5, p. 770-777 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    232 Scopus citations
  • Open Access
    10 Scopus citations
  • Epigenomics and metabolomics reveal the mechanism of the APOA2 -saturated fat intake interaction affecting obesity

    Lai, C. Q., Smith, C. E., Parnell, L. D., Lee, Y. C., Corella, D., Hopkins, P., Hidalgo, B. A., Aslibekyan, S., Province, M. A., Absher, D., Arnett, D. K., Tucker, K. L. & Ordovas, J. M., Jul 1 2018, In: American Journal of Clinical Nutrition. 108, 1, p. 188-200 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    47 Scopus citations
  • Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

    23andMe Research Team, COGENT (Cognitive Genomics Consortium) & Social Science Genetic Association Consortium, Aug 1 2018, In: Nature Genetics. 50, 8, p. 1112-1121 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1334 Scopus citations
  • Genetics of human longevity from incomplete data: New findings from the long life family study

    Yashin, A. I., Arbeev, K. G., Wu, D., Arbeeva, L. S., Bagley, O., Stallard, E., Kulminski, A. M., Akushevich, I., Fang, F., Wojczynski, M. K., Christensen, K., Newman, A. B., Boudreau, R. M., Province, M. A., Thielke, S., Perls, T. T., An, P., Elo, I. & Ukraintseva, S. V., Oct 8 2018, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 73, 11, p. 1472-1481 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    21 Scopus citations
  • Genome-Wide Interactions with Dairy Intake for Body Mass Index in Adults of European Descent

    Smith, C. E., Follis, J. L., Dashti, H. S., Tanaka, T., Graff, M., Fretts, A. M., Kilpeläinen, T. O., Wojczynski, M. K., Richardson, K., Nalls, M. A., Schulz, C. A., Liu, Y., Frazier-Wood, A. C., van Eekelen, E., Wang, C., de Vries, P. S., Mikkilä, V., Rohde, R., Psaty, B. M., Hansen, T., & 43 othersFeitosa, M. F., Lai, C. Q., Houston, D. K., Ferruci, L., Ericson, U., Wang, Z., de Mutsert, R., Oddy, W. H., de Jonge, E. A. L., Seppälä, I., Justice, A. E., Lemaitre, R. N., Sørensen, T. I. A., Province, M. A., Parnell, L. D., Garcia, M. E., Bandinelli, S., Orho-Melander, M., Rich, S. S., Rosendaal, F. R., Pennell, C. E., Kiefte-de Jong, J. C., Kähönen, M., Young, K. L., Pedersen, O., Aslibekyan, S., Rotter, J. I., Mook-Kanamori, D. O., Zillikens, M. C., Raitakari, O. T., North, K. E., Overvad, K., Arnett, D. K., Hofman, A., Lehtimäki, T., Tjønneland, A., Uitterlinden, A. G., Rivadeneira, F., Franco, O. H., German, J. B., Siscovick, D. S., Cupples, L. A. & Ordovás, J. M., Feb 1 2018, In: Molecular Nutrition and Food Research. 62, 3, 1700347.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    8 Scopus citations
  • How Well Does the Family Longevity Selection Score Work: A Validation Test Using the Utah Population Database

    Arbeeva, L. S., Hanson, H. A., Arbeev, K. G., Kulminski, A. M., Stallard, E., Ukraintseva, S. V., Wu, D., Boudreau, R. M., Province, M. A., Smith, K. R. & Yashin, A. I., Oct 1 2018, In: Frontiers in Public Health. 6, 277.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    6 Scopus citations
  • Meta-analysis of exome array data identifies six novel genetic loci for lung function

    Tobin, M. D., London, S. J., Jackson, V. E., Latourelle, J. C., Wain, L. V., Smith, A. V., Grove, M. L., Bartz, T. M., Obeidat, M., Province, M. A., Gao, W., Qaiser, B., Porteous, D. J., Cassano, P. A., Ahluwalia, T. S., Grarup, N., Li, J., Altmaier, E., Marten, J., Harris, S. E., & 87 othersManichaikul, A., Pottinger, T. D., Li-Gao, R., Lind-Thomsen, A., Mahajan, A., Lahousse, L., Imboden, M., Teumer, A., Prins, B., Lyytikäinen, L. P., Eiriksdottir, G., Franceschini, N., Sitlani, C. M., Brody, J. A., Bossé, Y., Timens, W., Kraja, A., Loukola, A., Tang, W., Liu, Y., Bork-Jensen, J., Justesen, J. M., Linneberg, A., Lange, L. A., Rawal, R., Karrasch, S., Huffman, J. E., Smith, B. H., Davies, G., Burkart, K. M., Mychaleckyj, J. C., Bonten, T. N., Enroth, S., Lind, L., Brusselle, G. G., Kumar, A., Stubbe, B., Kähönen, M., Wyss, A. B., Psaty, B. M., Heckbert, S. R., Hao, K., Rantanen, T., Kritchevsky, S. B., Lohman, K., Skaaby, T., Pisinger, C., Hansen, T., Schulz, H., Polasek, O., Campbell, A. I., Starr, J. M., Rich, S. S., Mook-Kanamori, D. O., Johansson, Å., Ingelsson, E., Uitterlinden, A. G., Weiss, S., Raitakari, O. T., Gudnason, V., North, K. E., Gharib, S. A., Sin, D. D., Taylor, K. D., O'Connor, G. T., Kaprio, J., Harris, T. B., Pederson, O., Vestergaard, H., Wilson, J. G., Strauch, K., Hayward, C., Kerr, S. M., Deary, I. J., Barr, R. G., de Mutsert, R., Gyllensten, U., Morris, A. P., Ikram, M. A., Probst-Hensch, N., Gläser, S., Zeggini, E., Lehtimäki, T., Strachan, D. P., Dupuis, J., Morrison, A. C. & Hall, I. P., 2018, In: Wellcome Open Research. 3, 4.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    3 Scopus citations
  • Meta-analysis of exome array data identifies six novel genetic loci for lung function.

    Understanding Society Scientific group, 2018, In: Wellcome Open Research. 3, 4.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    18 Scopus citations
  • Methods for detecting methylation by SNP interaction in GAW20 simulation

    Warwick Daw, E., Hicks, J., Lenzini, P., Lin, S. J., Wang, J., Williams, C., An, P., Province, M. A. & Kraja, A. T., Sep 17 2018, In: BMC Proceedings. 12, 37.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    2 Scopus citations
  • Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function

    Wyss, A. B., Sofer, T., Lee, M. K., Terzikhan, N., Nguyen, J. N., Lahousse, L., Latourelle, J. C., Smith, A. V., Bartz, T. M., Feitosa, M. F., Gao, W., Ahluwalia, T. S., Tang, W., Oldmeadow, C., Duan, Q., de Jong, K., Wojczynski, M. K., Wang, X. Q., Noordam, R., Hartwig, F. P., & 82 othersJackson, V. E., Wang, T., Obeidat, M., Hobbs, B. D., Huan, T., Gui, H., Parker, M. M., Hu, D., Mogil, L. S., Kichaev, G., Jin, J., Graff, M., Harris, T. B., Kalhan, R., Heckbert, S. R., Paternoster, L., Burkart, K. M., Liu, Y., Holliday, E. G., Wilson, J. G., Vonk, J. M., Sanders, J. L., Barr, R. G., de Mutsert, R., Menezes, A. M. B., Adams, H. H. H., van den Berge, M., Joehanes, R., Levin, A. M., Liberto, J., Launer, L. J., Morrison, A. C., Sitlani, C. M., Celedón, J. C., Kritchevsky, S. B., Scott, R. J., Christensen, K., Rotter, J. I., Bonten, T. N., Wehrmeister, F. C., Bossé, Y., Xiao, S., Oh, S., Franceschini, N., Brody, J. A., Kaplan, R. C., Lohman, K., McEvoy, M., Province, M. A., Rosendaal, F. R., Taylor, K. D., Nickle, D. C., Williams, L. K., Burchard, E. G., Wheeler, H. E., Sin, D. D., Gudnason, V., North, K. E., Fornage, M., Psaty, B. M., Myers, R. H., O’Connor, G., Hansen, T., Laurie, C. C., Cassano, P. A., Sung, J., Kim, W. J., Attia, J. R., Lange, L., Boezen, H. M., Thyagarajan, B., Rich, S. S., Mook-Kanamori, D. O., Horta, B. L., Uitterlinden, A. G., Im, H. K., Cho, M. H., Brusselle, G. G., Gharib, S. A., Dupuis, J., Manichaikul, A. & London, S. J., Dec 1 2018, In: Nature communications. 9, 1, 2976.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    68 Scopus citations
  • Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries

    Feitosa, M. F., Kraja, A. T., Chasman, D. I., Sung, Y. J., Winkler, T. W., Ntalla, I., Guo, X., Franceschini, N., Cheng, C. Y., Sim, X., Vojinovic, D., Marten, J., Musani, S. K., Li, C., Bentley, A. R., Brown, M. R., Schwander, K., Richard, M. A., Noordam, R., Aschard, H., & 252 othersBartz, T. M., Bielak, L. F., Dorajoo, R., Fisher, V., Hartwig, F. P., Horimoto, A. R. V. R., Lohman, K. K., Manning, A. K., Rankinen, T., Smith, A. V., Tajuddin, S. M., Wojczynski, M. K., Alver, M., Boissel, M., Cai, Q., Campbell, A., Chai, J. F., Chen, X., Divers, J., Gao, C., Goel, A., Hagemeijer, Y., Harris, S. E., He, M., Hsu, F. C., Jackson, A. U., Kähönen, M., Kasturiratne, A., Komulainen, P., Kühnel, B., Laguzzi, F., Luan, JA., Matoba, N., Nolte, I. M., Padmanabhan, S., Riaz, M., Rueedi, R., Robino, A., Said, M. A., Scott, R. A., Sofer, T., Stančáková, A., Takeuchi, F., Tayo, B. O., Van Der Most, P. J., Varga, T. V., Vitart, V., Wang, Y., Ware, E. B., Warren, H. R., Weiss, S., Wen, W., Yanek, L. R., Zhang, W., Zhao, J. H., Afaq, S., Amin, N., Amini, M., Arking, D. E., Aung, T., Boerwinkle, E., Borecki, I., Broeckel, U., Brown, M., Brumat, M., Burke, G. L., Canouil, M., Chakravarti, A., Charumathi, S., Chen, Y. D. I., Connell, J. M., Correa, A., De Las Fuentes, L., De Mutsert, R., De Silva, H. J., Deng, X., Ding, J., Duan, Q., Eaton, C. B., Ehret, G., Eppinga, R. N., Evangelou, E., Faul, J. D., Felix, S. B., Forouhi, N. G., Forrester, T., Franco, O. H., Friedlander, Y., Gandin, I., Gao, H., Ghanbari, M., Gigante, B., Gu, C. C., Gu, D., Hagenaars, S. P., Hallmans, G., Harris, T. B., He, J., Heikkinen, S., Heng, C. K., Hirata, M., Howard, B. V., Ikram, M. A., John, U., Katsuya, T., Khor, C. C., Kilpeläinen, T. O., Koh, W. P., Krieger, J. E., Kritchevsky, S. B., Kubo, M., Kuusisto, J., Lakka, T. A., Langefeld, C. D., Langenberg, C., Launer, L. J., Lehne, B., Lewis, C. E., Li, Y., Lin, S., Liu, J., Liu, J., Loh, M., Louie, T., Mägi, R., McKenzie, C. A., Meitinger, T., Metspalu, A., Milaneschi, Y., Milani, L., Mohlke, K. L., Momozawa, Y., Nalls, M. A., Nelson, C. P., Sotoodehnia, N., Norris, J. M., O'Connell, J. R., Palmer, N. D., Perls, T., Pedersen, N. L., Peters, A., Peyser, P. A., Poulter, N., Raffel, L. J., Raitakari, O. T., Roll, K., Rose, L. M., Rosendaal, F. R., Rotter, J. I., Schmidt, C. O., Schreiner, P. J., Schupf, N., Scott, W. R., Sever, P. S., Shi, Y., Sidney, S., Sims, M., Sitlani, C. M., Smith, J. A., Snieder, H., Starr, J. M., Strauch, K., Stringham, H. M., Tan, N. Y. Q., Tang, H., Taylor, K. D., Teo, Y. Y., Tham, Y. C., Turner, S. T., Uitterlinden, A. G., Vollenweider, P., Waldenberger, M., Wang, L., Wang, Y. X., Wei, W. B., Williams, C., Yao, J., Yu, C., Yuan, J. M., Zhao, W., Zonderman, A. B., Becker, D. M., Boehnke, M., Bowden, D. W., Chambers, J. C., Deary, I. J., Esko, T., Farrall, M., Franks, P. W., Freedman, B. I., Froguel, P., Gasparini, P., Gieger, C., Jonas, J. B., Kamatani, Y., Kato, N., Kooner, J. S., Kutalik, Z., Laakso, M., Laurie, C. C., Leander, K., Lehtimäki, T., Magnusson, P. K. E., Oldehinkel, A. J., Penninx, B. W. J. H., Polasek, O., Porteous, D. J., Rauramaa, R., Samani, N. J., Scott, J., Shu, X. O., Van Der Harst, P., Wagenknecht, L. E., Wareham, N. J., Watkins, H., Weir, D. R., Wickremasinghe, A. R., Wu, T., Zheng, W., Bouchard, C., Christensen, K., Evans, M. K., Gudnason, V., Horta, B. L., Kardia, S. L. R., Liu, Y., Pereira, A. C., Psaty, B. M., Ridker, P. M., Van Dam, R. M., Gauderman, W. J., Zhu, X., Mook-Kanamori, D. O., Fornage, M., Rotimi, C. N., Cupples, L. A., Kelly, T. N., Fox, E. R., Hayward, C., Van Duijn, C. M., Tai, E. S., Wong, T. Y., Kooperberg, C., Palmas, W., Rice, K., Morrison, A. C., Elliott, P., Caulfield, M. J., Munroe, P. B., Rao, D. C., Province, M. A. & Levy, D., Jun 2018, In: PloS one. 13, 6, e0198166.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    63 Scopus citations
  • Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes article

    ExomeBP Consortium, MAGIC Consortium & GIANT Consortium, Apr 1 2018, In: Nature Genetics. 50, 4, p. 559-571 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    278 Scopus citations
  • Simulation of a medication and methylation effects on triglycerides in the Genetic Analysis Workshop 20 06 Biological Sciences 0604 Genetics

    Kraja, A. T., An, P., Lenzini, P., Lin, S. J., Williams, C., Hicks, J. E., Warwick Daw, E. & Province, M. A., Sep 17 2018, In: BMC Proceedings. 12, 25.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    5 Scopus citations
  • The NIEHS TaRGET II Consortium and environmental epigenomics

    TaRGET II Consortium, Mar 6 2018, In: Nature Biotechnology. 36, 3, p. 225-227 3 p.

    Research output: Contribution to journalLetterpeer-review

    Open Access
    61 Scopus citations
  • VarExp: Estimating variance explained by genome-wide GxE summary statistics

    Laville, V., Bentley, A. R., Privé, F., Zhu, X., Gauderman, J., Winkler, T. W., Province, M., Rao, D. C. & Aschard, H., Oct 1 2018, In: Bioinformatics. 34, 19, p. 3412-3414 3 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    10 Scopus citations
  • 2017

    A novel TCF7L2 type 2 diabetes SNP identified from fine mapping in African American women

    MEDIA Consortium, Mar 1 2017, In: PloS one. 12, 3, e0172577.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    9 Scopus citations
  • Causal effect of plasminogen activator inhibitor type 1 on coronary heart disease

    CHARGE Consortium Hemostatic Factor Working Group, ICBP Consortium & CHARGE Consortium Subclinical Working Group, Jun 1 2017, In: Journal of the American Heart Association. 6, 6, e004918.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    92 Scopus citations
  • CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits

    Macé, A., Tuke, M. A., Deelen, P., Kristiansson, K., Mattsson, H., Nõukas, M., Sapkota, Y., Schick, U., Porcu, E., Rüeger, S., McDaid, A. F., Porteous, D., Winkler, T. W., Salvi, E., Shrine, N., Liu, X., Ang, W. Q., Zhang, W., Feitosa, M. F., Venturini, C., & 86 othersVan Der Most, P. J., Rosengren, A., Wood, A. R., Beaumont, R. N., Jones, S. E., Ruth, K. S., Yaghootkar, H., Tyrrell, J., Havulinna, A. S., Boers, H., Mägi, R., Kriebel, J., Müller-Nurasyid, M., Perola, M., Nieminen, M., Lokki, M. L., Kähönen, M., Viikari, J. S., Geller, F., Lahti, J., Palotie, A., Koponen, P., Lundqvist, A., Rissanen, H., Bottinger, E. P., Afaq, S., Wojczynski, M. K., Lenzini, P., Nolte, I. M., Sparsø, T., Schupf, N., Christensen, K., Perls, T. T., Newman, A. B., Werge, T., Snieder, H., Spector, T. D., Chambers, J. C., Koskinen, S., Melbye, M., Raitakari, O. T., Lehtimäki, T., Tobin, M. D., Wain, L. V., Sinisalo, J., Peters, A., Meitinger, T., Martin, N. G., Wray, N. R., Montgomery, G. W., Medland, S. E., Swertz, M. A., Vartiainen, E., Borodulin, K., Männistö, S., Murray, A., Bochud, M., Jacquemont, S., Rivadeneira, F., Hansen, T. F., Oldehinkel, A. J., Mangino, M., Province, M. A., Deloukas, P., Kooner, J. S., Freathy, R. M., Pennell, C., Feenstra, B., Strachan, D. P., Lettre, G., Hirschhorn, J., Cusi, D., Heid, I. M., Hayward, C., Männik, K., Beckmann, J. S., Loos, R. J. F., Nyholt, D. R., Metspalu, A., Eriksson, J. G., Weedon, M. N., Salomaa, V., Franke, L., Reymond, A., Frayling, T. M. & Kutalik, Z., Dec 1 2017, In: Nature communications. 8, 1, 744.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    52 Scopus citations
  • Genome- and CD4+ T-cell methylome-wide association study of circulating trimethylamine-N-oxide in the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN)

    Aslibekyan, S., Irvin, M. R., Hidalgo, B. A., Perry, R. T., Jeyarajah, E. J., Garcia, E., Shalaurova, I., Hopkins, P. N., Province, M. A., Tiwari, H. K., Ordovas, J. M., Absher, D. M. & Arnett, D. K., Jun 1 2017, In: Journal of Nutrition and Intermediary Metabolism. 8, p. 1-7 7 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    12 Scopus citations
  • Loss of Cardioprotective Effects at the ADAMTS7 Locus as a Result of Gene-Smoking Interactions

    Saleheen, D., Zhao, W., Young, R., Nelson, C. P., Ho, W., Ferguson, J. F., Rasheed, A., Ou, K., Nurnberg, S. T., Bauer, R. C., Goel, A., Do, R., Stewart, A. F. R., Hartiala, J., Zhang, W., Thorleifsson, G., Strawbridge, R. J., Sinisalo, J., Kanoni, S., Sedaghat, S., & 50 othersMarouli, E., Kristiansson, K., Zhao, J. H., Scott, R., Gauguier, D., Shah, S. H., Smith, A. V., Van Zuydam, N., Cox, A. J., Willenborg, C., Kessler, T., Zeng, L., Province, M. A., Ganna, A., Lind, L., Pedersen, N. L., White, C. C., Joensuu, A., Kleber, M. E., Hall, A. S., März, W., Salomaa, V., O'Donnell, C., Ingelsson, E., Feitosa, M. F., Erdmann, J., Bowden, D. W., Palmer, C. N. A., Gudnason, V., Faire, U. D., Zalloua, P., Wareham, N., Thompson, J. R., Kuulasmaa, K., Dedoussis, G., Perola, M., Dehghan, A., Chambers, J. C., Kooner, J., Allayee, H., Deloukas, P., McPherson, R., Stefansson, K., Schunkert, H., Kathiresan, S., Farrall, M., Marcel Frossard, P., Rader, D. J., Samani, N. J. & Reilly, M. P., Jun 13 2017, In: Circulation. 135, 24, p. 2336-2353 18 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    40 Scopus citations
  • New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

    behalf of the CHARGE EXOME BP, CHD Exome+, Exome BP, GoT2D:T2DGenes Consortia, The UK Biobank Cardio-Metabolic Traits Consortium Blood Pressure Working Group & The Understanding Society Scientific Group, Oct 1 2017, In: Circulation: Cardiovascular Genetics. 10, 5, e001778.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    45 Scopus citations
  • Sex Differences in Blood HDL-c, the Total Cholesterol/HDL-c Ratio, and Palmitoleic Acid are Not Associated with Variants in Common Candidate Genes

    Klingel, S. L., Roke, K., Hidalgo, B., Aslibekyan, S., Straka, R. J., An, P., Province, M. A., Hopkins, P. N., Arnett, D. K., Ordovas, J. M., Lai, C. Q. & Mutch, D. M., Dec 1 2017, In: Lipids. 52, 12, p. 969-980 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    17 Scopus citations
  • Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms

    the eMERGE Consortium, the DIAGRAM Consortium, the MuTHER Consortium, SIGMA T2D Consortium, the DIAGRAM Consortium, the MuTHER Consortium, SIGMA T2D Consortium, the MuTHER Consortium, SIGMA T2D Consortium, SIGMA T2D Consortium, MEDIA Consortium, the FIND Consortium, the eMERGE Consortium, the DIAGRAM Consortium, the MuTHER Consortium, SIGMA T2D Consortium, the eMERGE Consortium, the DIAGRAM Consortium, the MuTHER Consortium & SIGMA T2D Consortium, Jun 29 2017, In: Cell. 170, 1, p. 199-212.e20

    Research output: Contribution to journalArticlepeer-review

    Open Access
    112 Scopus citations
  • 2016

    A Framework for Interpreting Type I Error Rates from a Product-Term Model of Interaction Applied to Quantitative Traits

    Rao, T. J. & Province, M. A., Feb 1 2016, In: Genetic Epidemiology. 40, 2, p. 144-153 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    8 Scopus citations
  • An Empirical Comparison of Joint and Stratified Frameworks for Studying G × E Interactions: Systolic Blood Pressure and Smoking in the CHARGE Gene-Lifestyle Interactions Working Group

    Sung, Y. J., Winkler, T. W., Manning, A. K., Aschard, H., Gudnason, V., Harris, T. B., Smith, A. V., Boerwinkle, E., Brown, M. R., Morrison, A. C., Fornage, M., Lin, L. A., Richard, M., Bartz, T. M., Psaty, B. M., Hayward, C., Polasek, O., Marten, J., Rudan, I., Feitosa, M. F., & 38 othersKraja, A. T., Province, M. A., Deng, X., Fisher, V. A., Zhou, Y., Bielak, L. F., Smith, J., Huffman, J. E., Padmanabhan, S., Smith, B. H., Ding, J., Liu, Y., Lohman, K., Bouchard, C., Rankinen, T., Rice, T. K., Arnett, D., Schwander, K., Guo, X., Palmas, W., Rotter, J. I., Alfred, T., Bottinger, E. P., Loos, R. J. F., Amin, N., Franco, O. H., van Duijn, C. M., Vojinovic, D., Chasman, D. I., Ridker, P. M., Rose, L. M., Kardia, S., Zhu, X., Rice, K., Borecki, I. B., Rao, D. C., Gauderman, W. J. & Cupples, L. A., Jul 1 2016, In: Genetic Epidemiology. 40, 5, p. 404-415 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    18 Scopus citations
  • Assessment of postprandial triglycerides in clinical practice: Validation in a general population and coronary heart disease patients

    Perez-Martinez, P., Alcala-Diaz, J. F., Kabagambe, E. K., Garcia-Rios, A., Tsai, M. Y., Delgado-Lista, J., Kolovou, G., Straka, R. J., Gomez-Delgado, F., Hopkins, P. N., Marin, C., Borecki, I., Yubero-Serrano, E. M., Hixson, J. E., Camargo, A., Province, M. A., Lopez-Moreno, J., Rodriguez-Cantalejo, F., Tinahones, F. J., Mikhailidis, D. P., & 4 othersPerez-Jimenez, F., Arnett, D. K., Ordovas, J. M. & Lopez-Miranda, J., Sep 1 2016, In: Journal of Clinical Lipidology. 10, 5, p. 1163-1171 9 p.

    Research output: Contribution to journalArticlepeer-review

    22 Scopus citations
  • Candidate gene resequencing to identify rare, pedigree-specific variants influencing healthy aging phenotypes in the long life family study

    Druley, T. E., Wang, L., Lin, S. J., Lee, J. H., Zhang, Q., Daw, E. W., Abel, H. J., Chasnoff, S. E., Ramos, E. I., Levinson, B. T., Thyagarajan, B., Newman, A. B., Christensen, K., Mayeux, R. & Province, M. A., Apr 9 2016, In: BMC Geriatrics. 16, 1, 80.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    18 Scopus citations
  • Epigenome-wide association study of triglyceride postprandial responses to a high-fat dietary challenge

    Lai, C. Q., Wojczynski, M. K., Parnell, L. D., Hidalgo, B. A., Irvin, M. R., Aslibekyan, S., Province, M. A., Absher, D. M., Arnett, D. K. & Ordovás, J. M., 2016, In: Journal of lipid research. 57, 12, p. 2200-2207 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    33 Scopus citations
  • General Framework for Meta-Analysis of Haplotype Association Tests

    Wang, S., Zhao, J. H., An, P., Guo, X., Jensen, R. A., Marten, J., Huffman, J. E., Meidtner, K., Boeing, H., Campbell, A., Rice, K. M., Scott, R. A., Yao, J., Schulze, M. B., Wareham, N. J., Borecki, I. B., Province, M. A., Rotter, J. I., Hayward, C., Goodarzi, M. O., & 2 othersMeigs, J. B. & Dupuis, J., Apr 1 2016, In: Genetic Epidemiology. 40, 3, p. 244-252 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Genetic variants linked to education predict longevity

    Marioni, R. E., Ritchie, S. J., Joshi, P. K., Hagenaars, S. P., Okbay, A., Fischer, K., Adams, M. J., Hill, W. D., Davies, G., Nagy, R., Amador, C., Läll, K., Metspalu, A., Liewald, D. C., Campbell, A., Wilson, J. F., Hayward, C., Esko, T., Porteous, D. J., Gale, C. R., & 255 othersDeary, I. J., Okbay, A., Beauchamp, J. P., Fontana, M. A., Lee, J. J., Pers, T. H., Rietveld, C. A., Turley, P., Chen, G. B., Emilsson, V., Meddens, S. F., Oskarsson, S., Pickrell, J. K., Thom, K., Timshel, P., de Vlaming, R., Abdellaoui, A., Ahluwalia, T. S., Bacelis, J., Baumbach, C., Bjornsdottir, G., Brandsma, J. H., Concas, M. P., Derringer, J., Furlotte, N. A., Galesloot, T. E., Girotto, G., Gupta, R., Hall, L. M., Harris, S. E., Hofer, E., Horikoshi, M., Huffman, J. E., Kaasik, K., Kalafati, I. P., Karlsson, R., Kong, A., Lahti, J., van der Lee, S. J., de Leeuw, C., Lind, P. A., Lindgren, K. O., Liu, T., Mangino, M., Marten, J., Mihailov, E., Miller, M. B., van der Most, P. J., Oldmeadow, C., Payton, A., Pervjakova, N., Peyrot, W. J., Qian, Y., Raitakari, O., Rueedi, R., Salvi, E., Schmidt, B., Schraut, K. E., Shi, J., Smith, A. V., Poot, R. A., St Pourcain, B., Teumer, A., Thorleifsson, G., Verweij, N., Vuckovic, D., Wellmann, J., Westra, H. J., Yang, J., Zhao, W., Zhu, Z., Alizadeh, B. Z., Amin, N., Bakshi, A., Baumeister, S. E., Biino, G., Bønnelykke, K., Boyle, P. A., Campbell, H., Cappuccio, F. P., Davies, G., De Neve, J. E., Deloukas, P., Demuth, I., Ding, J., Eibich, P., Eisele, L., Eklund, N., Evans, D. M., Faul, J. D., Feitosa, M. F., Forstner, A. J., Gandin, I., Gunnarsson, B., Halldórsson, B. V., Harris, T. B., Heath, A. C., Hocking, L. J., Holliday, E. G., Homuth, G., Horan, M. A., Hottenga, J. J., de Jager, P. L., Joshi, P. K., Jugessur, A., Kaakinen, M. A., Kähönen, M., Kanoni, S., Keltigangas-Järvinen, L., Kiemeney, L. A., Kolcic, I., Koskinen, S., Kraja, A. T., Kroh, M., Kutalik, Z., Latvala, A., Launer, L. J., Lebreton, M. P., Levinson, D. F., Lichtenstein, P., Lichtner, P., Liewald, D. C., Loukola, A., Madden, P. A., Mägi, R., Mäki-Opas, T., Marioni, R. E., Marques-Vidal, P., Meddens, G. A., McMahon, G., Meisinger, C., Meitinger, T., Milaneschi, Y., Milani, L., Montgomery, G. W., Myhre, R., Nelson, C. P., Nyholt, D. R., Ollier, W. E., Palotie, A., Paternoster, L., Pedersen, N. L., Petrovic, K. E., Porteous, D. J., Räikkönen, K., Ring, S. M., Robino, A., Rostapshova, O., Rudan, I., Rustichini, A., Salomaa, V., Sanders, A. R., Sarin, A. P., Schmidt, H., Scott, R. J., Smith, B. H., Smith, J. A., Staessen, J. A., Steinhagen-Thiessen, E., Strauch, K., Terracciano, A., Ulivi, S., Vaccargiu, S., Quaye, L., van Rooij, F. J., Venturini, C., Vinkhuyzen, A. A., Völker, U., Völzke, H., Vonk, J. M., Vozzi, D., Waage, J., Ware, E. B., Willemsen, G., Attia, J. R., Bennett, D. A., Berger, K., Bertram, L., Bisgaard, H., Boomsma, D. I., Borecki, I. B., Bultmann, U., Chabris, C. F., Cucca, F., Cusi, D., Deary, I. J., Dedoussis, G. V., van Duijn, C. M., Eriksson, J. G., Franke, B., Franke, L., Gasparini, P., Gejman, P. V., Gieger, C., Grabe, H. J., Gratten, J., Groenen, P. J., Gudnason, V., van der Harst, P., Hayward, C., Hinds, D. A., Hoffmann, W., Hypponen, E., Iacono, W. G., Jacobsson, B., Järvelin, M. R., Jöckel, K. H., Kaprio, J., Kardia, S. L., Lehtimäki, T., Lehrer, S. F., Magnusson, P. K., Martin, N. G., McGue, M., Metspalu, A., Pendleton, N., Penninx, B. W., Perola, M., Pirastu, N., Pirastu, M., Polasek, O., Posthuma, D., Power, C., Province, M. A., Samani, N. J., Schlessinger, D., Schmidt, R., Sørensen, T. I., Spector, T. D., Stefansson, K., Thorsteinsdottir, U., Thurik, A. R., Timpson, N. J., Tiemeier, H., Tung, J. Y., Uitterlinden, A. G., Vitart, V., Vollenweider, P., Weir, D. R., Wilson, J. F., Wright, A. F., Conley, D. C., Krueger, R. F., Smith, G. D., Hofman, A., Laibson, D. I., Medland, S. E., Meyer, M. N., Yang, J., Johannesson, M., Visscher, P. M., Esko, T., Koellinger, P. D., Cesarini, D. & Benjamin, D. J., Nov 22 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 47, p. 13366-13371 6 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    52 Scopus citations
  • Genome-wide association study identifies 74 loci associated with educational attainment

    Okbay, A., Beauchamp, J. P., Fontana, M. A., Lee, J. J., Pers, T. H., Rietveld, C. A., Turley, P., Chen, G. B., Emilsson, V., Meddens, S. F. W., Oskarsson, S., Pickrell, J. K., Thom, K., Timshel, P., De Vlaming, R., Abdellaoui, A., Ahluwalia, T. S., Bacelis, J., Baumbach, C., Bjornsdottir, G., & 235 othersBrandsma, J. H., Pina Concas, M., Derringer, J., Furlotte, N. A., Galesloot, T. E., Girotto, G., Gupta, R., Hall, L. M., Harris, S. E., Hofer, E., Horikoshi, M., Huffman, J. E., Kaasik, K., Kalafati, I. P., Karlsson, R., Kong, A., Lahti, J., Van Der Lee, S. J., Deleeuw, C., Lind, P. A., Lindgren, K. O., Liu, T., Mangino, M., Marten, J., Mihailov, E., Miller, M. B., Van Der Most, P. J., Oldmeadow, C., Payton, A., Pervjakova, N., Peyrot, W. J., Qian, Y., Raitakari, O., Rueedi, R., Salvi, E., Schmidt, B., Schraut, K. E., Shi, J., Smith, A. V., Poot, R. A., St Pourcain, B., Teumer, A., Thorleifsson, G., Verweij, N., Vuckovic, D., Wellmann, J., Westra, H. J., Yang, J., Zhao, W., Zhu, Z., Alizadeh, B. Z., Amin, N., Bakshi, A., Baumeister, S. E., Biino, G., Bønnelykke, K., Boyle, P. A., Campbell, H., Cappuccio, F. P., Davies, G., De Neve, J. E., Deloukas, P., Demuth, I., Ding, J., Eibich, P., Eisele, L., Eklund, N., Evans, D. M., Faul, J. D., Feitosa, M. F., Forstner, A. J., Gandin, I., Gunnarsson, B., Halldórsson, B. V., Harris, T. B., Holliday, E. G., Heath, A. C., Hocking, L. J., Homuth, G., Horan, M. A., Hottenga, J. J., De Jager, P. L., Joshi, P. K., Jugessur, A., Kaakinen, M. A., Kähönen, M., Kanoni, S., Keltigangas-Järvinen, L., Kiemeney, L. A. L. M., Kolcic, I., Koskinen, S., Kraja, A. T., Kroh, M., Kutalik, Z., Latvala, A., Launer, L. J., Lebreton, M. P., Levinson, D. F., Lichtenstein, P., Lichtner, P., Liewald, D. C. M., Loukola, A., Madden, P. A., Mägi, R., Mäki-Opas, T., Marioni, R. E., Marques-Vidal, P., Meddens, G. A., Mcmahon, G., Meisinger, C., Meitinger, T., Milaneschi, Y., Milani, L., Montgomery, G. W., Myhre, R., Nelson, C. P., Nyholt, D. R., Ollier, W. E. R., Palotie, A., Paternoster, L., Pedersen, N. L., Petrovic, K. E., Porteous, D. J., Raïkkönen, K., Ring, S. M., Robino, A., Rostapshova, O., Rudan, I., Rustichini, A., Salomaa, V., Sanders, A. R., Sarin, A. P., Schmidt, H., Scott, R. J., Smith, B. H., Smith, J. A., Staessen, J. A., Steinhagen-Thiessen, E., Strauch, K., Terracciano, A., Tobin, M. D., Ulivi, S., Vaccargiu, S., Quaye, L., Van Rooij, F. J. A., Venturini, C., Vinkhuyzen, A. A. E., Völker, U., Völzke, H., Vonk, J. M., Vozzi, D., Waage, J., Ware, E. B., Willemsen, G., Attia, J. R., Bennett, D. A., Berger, K., Bertram, L., Bisgaard, H., Boomsma, D. I., Borecki, I. B., Bültmann, U., Chabris, C. F., Cucca, F., Cusi, D., Deary, I. J., Dedoussis, G. V., Van Duijn, C. M., Eriksson, J. G., Franke, B., Franke, L., Gasparini, P., Gejman, P. V., Gieger, C., Grabe, H. J., Gratten, J., Groenen, P. J. F., Gudnason, V., Van Der Harst, P., Hayward, C., Hinds, D. A., Hoffmann, W., Hyppönen, E., Iacono, W. G., Jacobsson, B., Järvelin, M. R., Jöckel, K. H., Kaprio, J., Kardia, S. L. R., Lehtimäki, T., Lehrer, S. F., Magnusson, P. K. E., Martin, N. G., Mcgue, M., Metspalu, A., Pendleton, N., Penninx, B. W. J. H., Perola, M., Pirastu, N., Pirastu, M., Polasek, O., Posthuma, D., Power, C., Province, M. A., Samani, N. J., Schlessinger, D., Schmidt, R., Sørensen, T. I. A., Spector, T. D., Stefansson, K., Thorsteinsdottir, U., Thurik, A. R., Timpson, N. J., Tiemeier, H., Tung, J. Y., Uitterlinden, A. G., Vitart, V., Vollenweider, P., Weir, D. R., Wilson, J. F., Wright, A. F., Conley, D. C., Krueger, R. F., Davey Smith, G., Hofman, A., Laibson, D. I., Medland, S. E., Meyer, M. N., Yang, J., Johannesson, M., Visscher, P. M., Esko, T., Koellinger, P. D., Cesarini, D. & Benjamin, D. J., May 11 2016, In: Nature. 533, 7604, p. 539-542 4 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    806 Scopus citations
  • Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis

    Natarajan, P., Bis, J. C., Bielak, L. F., Cox, A. J., Dörr, M., Feitosa, M. F., Franceschini, N., Guo, X., Hwang, S. J., Isaacs, A., Jhun, M. A., Kavousi, M., Li-Gao, R., Lyytikäinen, L. P., Marioni, R. E., Schminke, U., Stitziel, N. O., Tada, H., Van Setten, J., Smith, A. V., & 80 othersVojinovic, D., Yanek, L. R., Yao, J., Yerges-Armstrong, L. M., Amin, N., Baber, U., Borecki, I. B., Carr, J. J., Chen, Y. D. I., Cupples, L. A., De Jong, P. A., De Koning, H., De Vos, B. D., Demirkan, A., Fuster, V., Franco, O. H., Goodarzi, M. O., Harris, T. B., Heckbert, S. R., Heiss, G., Hoffmann, U., Hofman, A., Išgum, I., Jukema, J. W., Kähönen, M., Kardia, S. L. R., Kral, B. G., Launer, L. J., Massaro, J., Mehran, R., Mitchell, B. D., Mosley, T. H., De Mutsert, R., Newman, A. B., Nguyen, K. D., North, K. E., O'Connell, J. R., Oudkerk, M., Pankow, J. S., Peloso, G. M., Post, W., Province, M. A., Raffield, L. M., Raitakari, O. T., Reilly, D. F., Rivadeneira, F., Rosendaal, F., Sartori, S., Taylor, K. D., Teumer, A., Trompet, S., Turner, S. T., Uitterlinden, A. G., Vaidya, D., Van Der Lugt, A., Völker, U., Wardlaw, J. M., Wassel, C. L., Weiss, S., Wojczynski, M. K., Becker, D. M., Becker, L. C., Boerwinkle, E., Bowden, D. W., Deary, I. J., Dehghan, A., Felix, S. B., Gudnason, V., Lehtimäki, T., Mathias, R., Mook-Kanamori, D. O., Psaty, B. M., Rader, D. J., Rotter, J. I., Wilson, J. G., Van Duijn, C. M., Völzke, H., Kathiresan, S., Peyser, P. A. & O'Donnell, C. J., Dec 1 2016, In: Circulation: Cardiovascular Genetics. 9, 6, p. 511-520 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    45 Scopus citations
  • Persistent and newly developed chronic bronchitis are associated with worse outcomes in chronic obstructive pulmonary disease

    the COPDGene Investigators, Jul 1 2016, In: Annals of the American Thoracic Society. 13, 7, p. 1016-1025 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    34 Scopus citations
  • Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin

    Liu, C. T., Raghavan, S., Maruthur, N., Kabagambe, E. K., Hong, J., Ng, M. C. Y., Hivert, M. F., Lu, Y., An, P., Bentley, A. R., Drolet, A. M., Gaulton, K. J., Guo, X., Armstrong, L. L., Irvin, M. R., Li, M., Lipovich, L., Rybin, D. V., Taylor, K. D., Agyemang, C., & 95 othersPalmer, N. D., Cade, B. E., Chen, W. M., Dauriz, M., Delaney, J. A. C., Edwards, T. L., Evans, D. S., Evans, M. K., Lange, L. A., Leong, A., Liu, J., Liu, Y., Nayak, U., Patel, S. R., Porneala, B. C., Rasmussen-Torvik, L. J., Snijder, M. B., Stallings, S. C., Tanaka, T., Yanek, L. R., Zhao, W., Becker, D. M., Bielak, L. F., Biggs, M. L., Bottinger, E. P., Bowden, D. W., Chen, G., Correa, A., Couper, D. J., Crawford, D. C., Cushman, M., Eicher, J. D., Fornage, M., Franceschini, N., Fu, Y. P., Goodarzi, M. O., Gottesman, O., Hara, K., Harris, T. B., Jensen, R. A., Johnson, A. D., Jhun, M. A., Karter, A. J., Keller, M. F., Kho, A. N., Kizer, J. R., Krauss, R. M., Langefeld, C. D., Li, X., Liang, J., Liu, S., Lowe, W. L., Mosley, T. H., North, K. E., Pacheco, J. A., Peyser, P. A., Patrick, A. L., Rice, K. M., Selvin, E., Sims, M., Smith, J. A., Tajuddin, S. M., Vaidya, D., Wren, M. P., Yao, J., Zhu, X., Ziegler, J. T., Zmuda, J. M., Zonderman, A. B., Zwinderman, A. H., Adeyemo, A., Boerwinkle, E., Ferrucci, L., Hayes, M. G., Kardia, S. L. R., Miljkovic, I., Pankow, J. S., Rotimi, C. N., Sale, M. M., Wagenknecht, L. E., Arnett, D. K., Chen, Y. D. I., Nalls, M. A., Province, M. A., Kao, W. H. L., Siscovick, D. S., Psaty, B. M., Wilson, J. G., Loos, R. J. F., Dupuis, J., Rich, S. S., Florez, J. C., Rotter, J. I., Morris, A. P. & Meigs, J. B., Jul 7 2016, In: American journal of human genetics. 99, 1, p. 56-75 20 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    44 Scopus citations
  • 2015

    Admixture mapping of coronary artery calcification in African Americans from the NHLBI family heart study

    Gomez, F., Wang, L., Abel, H., Zhang, Q., Province, M. A. & Borecki, I. B., Apr 23 2015, In: BMC genetics. 16, 1, 42.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    8 Scopus citations
  • Consumption of meat is associated with higher fasting glucose and insulin concentrations regardless of glucose and insulin genetic risk scores: A meta-analysis of 50,345 Caucasians

    Fretts, A. M., Follis, J. L., Nettleton, J. A., Lemaitre, R. N., Ngwa, J. S., Wojczynski, M. K., Kalafati, I. P., Varga, T. V., Frazier-Wood, A. C., Houston, D. K., Lahti, J., Ericson, U., Van Den Hooven, E. H., Mikkilä, V., Kiefte-De Jong, J. C., Mozaffarian, D., Rice, K., Renström, F., North, K. E., McKeown, N. M., & 42 othersFeitosa, M. F., Kanoni, S., Smith, C. E., Garcia, M. E., Tiainen, A. M., Sonestedt, E., Manichaikul, A., Van Rooij, F. J. A., Dimitriou, M., Raitakari, O., Pankow, J. S., Djoussé, L., Province, M. A., Hu, F. B., Lai, C. Q., Keller, M. F., Perälä, M. M., Rotter, J. I., Hofman, A., Graff, M., Kähönen, M., Mukamal, K., Johansson, I., Ordovas, J. M., Liu, Y., Männistö, S., Uitterlinden, A. G., Deloukas, P., Seppälä, I., Psaty, B. M., Cupples, L. A., Borecki, I. B., Franks, P. W., Arnett, D. K., Nalls, M. A., Eriksson, J. G., Orho-Melander, M., Franco, O. H., Lehtimäki, T., Dedoussis, G. V., Meigs, J. B. & Siscovick, D. S., Nov 1 2015, In: American Journal of Clinical Nutrition. 102, 5, p. 1266-1278 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    65 Scopus citations