Michael Province

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Michael Province

Professor of Genetics, Professor of Biostatistics

 https://orcid.org/0000-0001-6102-774X

    Willing to Mentor

    Available to Mentor:

    PhD/MSTP Students

    • 39645
      Citations
    1980 …2023

    Research activity per year

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    Search results

    • 2019

      Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity

      Lifelines Cohort Study, Dec 1 2019, In: Nature communications. 10, 1, 376.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      47 Scopus citations
    • 2018

      A high throughput, functional screen of human Body Mass Index GWAS loci using tissue-specific RNAi Drosophila melanogaster crosses

      Baranski, T. J., Kraja, A. T., Fink, J. L., Feitosa, M., Lenzini, P. A., Borecki, I. B., Liu, C. T., Cupples, L. A., North, K. E. & Province, M. A., Apr 2018, In: PLoS genetics. 14, 4, e1007222.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      17 Scopus citations

    • A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

      The CHARGE Neurology Working Group, The COGENT-Kidney Consortium, The GIANT Consortium & Lifelines Cohort Study, Mar 1 2018, In: American journal of human genetics. 102, 3, p. 375-400 26 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      69 Scopus citations

    • An exome-wide sequencing study of lipid response to high-fat meal and fenofibrate in Caucasians from the GOLDN cohort

      Geng, X., Irvin, M. R., Hidalgo, B., Aslibekyan, S., Srinivasasainagendra, V., An, P., Frazier-Wood, A. C., Tiwari, H. K., Dave, T., Ryan, K., Ordovas, J. M., Straka, R. J., Feitosa, M. F., Hopkins, P. N., Borecki, I., Province, M. A., Mitchell, B. D., Arnett, D. K. & Zhi, D., 2018, In: Journal of lipid research. 59, 4, p. 722-729 8 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      5 Scopus citations

    • Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and Tamoxifen Therapy

      Goetz, M. P., Sangkuhl, K., Guchelaar, H. J., Schwab, M., Province, M., Whirl-Carrillo, M., Symmans, W. F., McLeod, H. L., Ratain, M. J., Zembutsu, H., Gaedigk, A., van Schaik, R. H., Ingle, J. N., Caudle, K. E. & Klein, T. E., May 2018, In: Clinical pharmacology and therapeutics. 103, 5, p. 770-777 8 p.

      Research output: Contribution to journal › Article › peer-review

      179 Scopus citations

    • Data for GAW20: Genome-wide DNA sequence variation and epigenome-wide DNA methylation before and after fenofibrate treatment in a family study of metabolic phenotypes 06 Biological Sciences 0604 Genetics

      Aslibekyan, S., Almasy, L., Province, M. A., Absher, D. M. & Arnett, D. K., Sep 17 2018, In: BMC Proceedings. 12, 35.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      10 Scopus citations

    • Epigenomics and metabolomics reveal the mechanism of the APOA2 -saturated fat intake interaction affecting obesity

      Lai, C. Q., Smith, C. E., Parnell, L. D., Lee, Y. C., Corella, D., Hopkins, P., Hidalgo, B. A., Aslibekyan, S., Province, M. A., Absher, D., Arnett, D. K., Tucker, K. L. & Ordovas, J. M., Jul 1 2018, In: American Journal of Clinical Nutrition. 108, 1, p. 188-200 13 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      36 Scopus citations

    • Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

      23andMe Research Team, COGENT (Cognitive Genomics Consortium) & Social Science Genetic Association Consortium, Aug 1 2018, In: Nature Genetics. 50, 8, p. 1112-1121 10 p.

      Research output: Contribution to journal › Article › peer-review

      940 Scopus citations

    • Genetics of human longevity from incomplete data: New findings from the long life family study

      Yashin, A. I., Arbeev, K. G., Wu, D., Arbeeva, L. S., Bagley, O., Stallard, E., Kulminski, A. M., Akushevich, I., Fang, F., Wojczynski, M. K., Christensen, K., Newman, A. B., Boudreau, R. M., Province, M. A., Thielke, S., Perls, T. T., An, P., Elo, I. & Ukraintseva, S. V., Oct 8 2018, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 73, 11, p. 1472-1481 10 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      17 Scopus citations

    • Genome-Wide Interactions with Dairy Intake for Body Mass Index in Adults of European Descent

      Smith, C. E., Follis, J. L., Dashti, H. S., Tanaka, T., Graff, M., Fretts, A. M., Kilpeläinen, T. O., Wojczynski, M. K., Richardson, K., Nalls, M. A., Schulz, C. A., Liu, Y., Frazier-Wood, A. C., van Eekelen, E., Wang, C., de Vries, P. S., Mikkilä, V., Rohde, R., Psaty, B. M., Hansen, T., & 43 othersFeitosa, M. F., Lai, C. Q., Houston, D. K., Ferruci, L., Ericson, U., Wang, Z., de Mutsert, R., Oddy, W. H., de Jonge, E. A. L., Seppälä, I., Justice, A. E., Lemaitre, R. N., Sørensen, T. I. A., Province, M. A., Parnell, L. D., Garcia, M. E., Bandinelli, S., Orho-Melander, M., Rich, S. S., Rosendaal, F. R., Pennell, C. E., Kiefte-de Jong, J. C., Kähönen, M., Young, K. L., Pedersen, O., Aslibekyan, S., Rotter, J. I., Mook-Kanamori, D. O., Zillikens, M. C., Raitakari, O. T., North, K. E., Overvad, K., Arnett, D. K., Hofman, A., Lehtimäki, T., Tjønneland, A., Uitterlinden, A. G., Rivadeneira, F., Franco, O. H., German, J. B., Siscovick, D. S., Cupples, L. A. & Ordovás, J. M., Feb 1 2018, In: Molecular Nutrition and Food Research. 62, 3, 1700347.

      Research output: Contribution to journal › Article › peer-review

      6 Scopus citations

    • How Well Does the Family Longevity Selection Score Work: A Validation Test Using the Utah Population Database

      Arbeeva, L. S., Hanson, H. A., Arbeev, K. G., Kulminski, A. M., Stallard, E., Ukraintseva, S. V., Wu, D., Boudreau, R. M., Province, M. A., Smith, K. R. & Yashin, A. I., Oct 1 2018, In: Frontiers in Public Health. 6, 277.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      5 Scopus citations

    • Meta-analysis of exome array data identifies six novel genetic loci for lung function

      Tobin, M. D., London, S. J., Jackson, V. E., Latourelle, J. C., Wain, L. V., Smith, A. V., Grove, M. L., Bartz, T. M., Obeidat, M., Province, M. A., Gao, W., Qaiser, B., Porteous, D. J., Cassano, P. A., Ahluwalia, T. S., Grarup, N., Li, J., Altmaier, E., Marten, J., Harris, S. E., & 87 othersManichaikul, A., Pottinger, T. D., Li-Gao, R., Lind-Thomsen, A., Mahajan, A., Lahousse, L., Imboden, M., Teumer, A., Prins, B., Lyytikäinen, L. P., Eiriksdottir, G., Franceschini, N., Sitlani, C. M., Brody, J. A., Bossé, Y., Timens, W., Kraja, A., Loukola, A., Tang, W., Liu, Y., Bork-Jensen, J., Justesen, J. M., Linneberg, A., Lange, L. A., Rawal, R., Karrasch, S., Huffman, J. E., Smith, B. H., Davies, G., Burkart, K. M., Mychaleckyj, J. C., Bonten, T. N., Enroth, S., Lind, L., Brusselle, G. G., Kumar, A., Stubbe, B., Kähönen, M., Wyss, A. B., Psaty, B. M., Heckbert, S. R., Hao, K., Rantanen, T., Kritchevsky, S. B., Lohman, K., Skaaby, T., Pisinger, C., Hansen, T., Schulz, H., Polasek, O., Campbell, A. I., Starr, J. M., Rich, S. S., Mook-Kanamori, D. O., Johansson, Å., Ingelsson, E., Uitterlinden, A. G., Weiss, S., Raitakari, O. T., Gudnason, V., North, K. E., Gharib, S. A., Sin, D. D., Taylor, K. D., O'Connor, G. T., Kaprio, J., Harris, T. B., Pederson, O., Vestergaard, H., Wilson, J. G., Strauch, K., Hayward, C., Kerr, S. M., Deary, I. J., Barr, R. G., de Mutsert, R., Gyllensten, U., Morris, A. P., Ikram, M. A., Probst-Hensch, N., Gläser, S., Zeggini, E., Lehtimäki, T., Strachan, D. P., Dupuis, J., Morrison, A. C. & Hall, I. P., 2018, In: Wellcome Open Research. 3, 4.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      3 Scopus citations

    • Meta-analysis of exome array data identifies six novel genetic loci for lung function [version 1; peer review: 1 approved, 1 approved with reservations]

      Understanding Society Scientific group, 2018, In: Wellcome Open Research. 3, 4.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      15 Scopus citations

    • Methods for detecting methylation by SNP interaction in GAW20 simulation

      Warwick Daw, E., Hicks, J., Lenzini, P., Lin, S. J., Wang, J., Williams, C., An, P., Province, M. A. & Kraja, A. T., Sep 17 2018, In: BMC Proceedings. 12, 37.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      2 Scopus citations

    • Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function

      Wyss, A. B., Sofer, T., Lee, M. K., Terzikhan, N., Nguyen, J. N., Lahousse, L., Latourelle, J. C., Smith, A. V., Bartz, T. M., Feitosa, M. F., Gao, W., Ahluwalia, T. S., Tang, W., Oldmeadow, C., Duan, Q., de Jong, K., Wojczynski, M. K., Wang, X. Q., Noordam, R., Hartwig, F. P., & 82 othersJackson, V. E., Wang, T., Obeidat, M., Hobbs, B. D., Huan, T., Gui, H., Parker, M. M., Hu, D., Mogil, L. S., Kichaev, G., Jin, J., Graff, M., Harris, T. B., Kalhan, R., Heckbert, S. R., Paternoster, L., Burkart, K. M., Liu, Y., Holliday, E. G., Wilson, J. G., Vonk, J. M., Sanders, J. L., Barr, R. G., de Mutsert, R., Menezes, A. M. B., Adams, H. H. H., van den Berge, M., Joehanes, R., Levin, A. M., Liberto, J., Launer, L. J., Morrison, A. C., Sitlani, C. M., Celedón, J. C., Kritchevsky, S. B., Scott, R. J., Christensen, K., Rotter, J. I., Bonten, T. N., Wehrmeister, F. C., Bossé, Y., Xiao, S., Oh, S., Franceschini, N., Brody, J. A., Kaplan, R. C., Lohman, K., McEvoy, M., Province, M. A., Rosendaal, F. R., Taylor, K. D., Nickle, D. C., Williams, L. K., Burchard, E. G., Wheeler, H. E., Sin, D. D., Gudnason, V., North, K. E., Fornage, M., Psaty, B. M., Myers, R. H., O’Connor, G., Hansen, T., Laurie, C. C., Cassano, P. A., Sung, J., Kim, W. J., Attia, J. R., Lange, L., Boezen, H. M., Thyagarajan, B., Rich, S. S., Mook-Kanamori, D. O., Horta, B. L., Uitterlinden, A. G., Im, H. K., Cho, M. H., Brusselle, G. G., Gharib, S. A., Dupuis, J., Manichaikul, A. & London, S. J., Dec 1 2018, In: Nature communications. 9, 1, 2976.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      52 Scopus citations

    • Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries

      Feitosa, M. F., Kraja, A. T., Chasman, D. I., Sung, Y. J., Winkler, T. W., Ntalla, I., Guo, X., Franceschini, N., Cheng, C. Y., Sim, X., Vojinovic, D., Marten, J., Musani, S. K., Li, C., Bentley, A. R., Brown, M. R., Schwander, K., Richard, M. A., Noordam, R., Aschard, H., & 252 othersBartz, T. M., Bielak, L. F., Dorajoo, R., Fisher, V., Hartwig, F. P., Horimoto, A. R. V. R., Lohman, K. K., Manning, A. K., Rankinen, T., Smith, A. V., Tajuddin, S. M., Wojczynski, M. K., Alver, M., Boissel, M., Cai, Q., Campbell, A., Chai, J. F., Chen, X., Divers, J., Gao, C., Goel, A., Hagemeijer, Y., Harris, S. E., He, M., Hsu, F. C., Jackson, A. U., Kähönen, M., Kasturiratne, A., Komulainen, P., Kühnel, B., Laguzzi, F., Luan, JA., Matoba, N., Nolte, I. M., Padmanabhan, S., Riaz, M., Rueedi, R., Robino, A., Said, M. A., Scott, R. A., Sofer, T., Stančáková, A., Takeuchi, F., Tayo, B. O., Van Der Most, P. J., Varga, T. V., Vitart, V., Wang, Y., Ware, E. B., Warren, H. R., Weiss, S., Wen, W., Yanek, L. R., Zhang, W., Zhao, J. H., Afaq, S., Amin, N., Amini, M., Arking, D. E., Aung, T., Boerwinkle, E., Borecki, I., Broeckel, U., Brown, M., Brumat, M., Burke, G. L., Canouil, M., Chakravarti, A., Charumathi, S., Chen, Y. D. I., Connell, J. M., Correa, A., De Las Fuentes, L., De Mutsert, R., De Silva, H. J., Deng, X., Ding, J., Duan, Q., Eaton, C. B., Ehret, G., Eppinga, R. N., Evangelou, E., Faul, J. D., Felix, S. B., Forouhi, N. G., Forrester, T., Franco, O. H., Friedlander, Y., Gandin, I., Gao, H., Ghanbari, M., Gigante, B., Gu, C. C., Gu, D., Hagenaars, S. P., Hallmans, G., Harris, T. B., He, J., Heikkinen, S., Heng, C. K., Hirata, M., Howard, B. V., Ikram, M. A., John, U., Katsuya, T., Khor, C. C., Kilpeläinen, T. O., Koh, W. P., Krieger, J. E., Kritchevsky, S. B., Kubo, M., Kuusisto, J., Lakka, T. A., Langefeld, C. D., Langenberg, C., Launer, L. J., Lehne, B., Lewis, C. E., Li, Y., Lin, S., Liu, J., Liu, J., Loh, M., Louie, T., Mägi, R., McKenzie, C. A., Meitinger, T., Metspalu, A., Milaneschi, Y., Milani, L., Mohlke, K. L., Momozawa, Y., Nalls, M. A., Nelson, C. P., Sotoodehnia, N., Norris, J. M., O'Connell, J. R., Palmer, N. D., Perls, T., Pedersen, N. L., Peters, A., Peyser, P. A., Poulter, N., Raffel, L. J., Raitakari, O. T., Roll, K., Rose, L. M., Rosendaal, F. R., Rotter, J. I., Schmidt, C. O., Schreiner, P. J., Schupf, N., Scott, W. R., Sever, P. S., Shi, Y., Sidney, S., Sims, M., Sitlani, C. M., Smith, J. A., Snieder, H., Starr, J. M., Strauch, K., Stringham, H. M., Tan, N. Y. Q., Tang, H., Taylor, K. D., Teo, Y. Y., Tham, Y. C., Turner, S. T., Uitterlinden, A. G., Vollenweider, P., Waldenberger, M., Wang, L., Wang, Y. X., Wei, W. B., Williams, C., Yao, J., Yu, C., Yuan, J. M., Zhao, W., Zonderman, A. B., Becker, D. M., Boehnke, M., Bowden, D. W., Chambers, J. C., Deary, I. J., Esko, T., Farrall, M., Franks, P. W., Freedman, B. I., Froguel, P., Gasparini, P., Gieger, C., Jonas, J. B., Kamatani, Y., Kato, N., Kooner, J. S., Kutalik, Z., Laakso, M., Laurie, C. C., Leander, K., Lehtimäki, T., Magnusson, P. K. E., Oldehinkel, A. J., Penninx, B. W. J. H., Polasek, O., Porteous, D. J., Rauramaa, R., Samani, N. J., Scott, J., Shu, X. O., Van Der Harst, P., Wagenknecht, L. E., Wareham, N. J., Watkins, H., Weir, D. R., Wickremasinghe, A. R., Wu, T., Zheng, W., Bouchard, C., Christensen, K., Evans, M. K., Gudnason, V., Horta, B. L., Kardia, S. L. R., Liu, Y., Pereira, A. C., Psaty, B. M., Ridker, P. M., Van Dam, R. M., Gauderman, W. J., Zhu, X., Mook-Kanamori, D. O., Fornage, M., Rotimi, C. N., Cupples, L. A., Kelly, T. N., Fox, E. R., Hayward, C., Van Duijn, C. M., Tai, E. S., Wong, T. Y., Kooperberg, C., Palmas, W., Rice, K., Morrison, A. C., Elliott, P., Caulfield, M. J., Munroe, P. B., Rao, D. C., Province, M. A. & Levy, D., Jun 2018, In: PloS one. 13, 6, e0198166.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      46 Scopus citations

    • Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes article

      ExomeBP Consortium, MAGIC Consortium & GIANT Consortium, Apr 1 2018, In: Nature Genetics. 50, 4, p. 559-571 13 p.

      Research output: Contribution to journal › Article › peer-review

      220 Scopus citations

    • Simulation of a medication and methylation effects on triglycerides in the Genetic Analysis Workshop 20 06 Biological Sciences 0604 Genetics

      Kraja, A. T., An, P., Lenzini, P., Lin, S. J., Williams, C., Hicks, J. E., Warwick Daw, E. & Province, M. A., Sep 17 2018, In: BMC Proceedings. 12, 25.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      4 Scopus citations

    • The NIEHS TaRGET II Consortium and environmental epigenomics

      TaRGET II Consortium, Mar 6 2018, In: Nature Biotechnology. 36, 3, p. 225-227 3 p.

      Research output: Contribution to journal › Letter › peer-review

      48 Scopus citations

    • VarExp: Estimating variance explained by genome-wide GxE summary statistics

      Laville, V., Bentley, A. R., Privé, F., Zhu, X., Gauderman, J., Winkler, T. W., Province, M., Rao, D. C. & Aschard, H., Oct 1 2018, In: Bioinformatics. 34, 19, p. 3412-3414 3 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      7 Scopus citations
    • 2017

      A novel TCF7L2 type 2 diabetes SNP identified from fine mapping in African American women

      MEDIA Consortium, Mar 1 2017, In: PloS one. 12, 3, e0172577.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      8 Scopus citations

    • Causal effect of plasminogen activator inhibitor type 1 on coronary heart disease

      CHARGE Consortium Hemostatic Factor Working Group, ICBP Consortium & CHARGE Consortium Subclinical Working Group, Jun 1 2017, In: Journal of the American Heart Association. 6, 6, e004918.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      69 Scopus citations

    • CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits

      Macé, A., Tuke, M. A., Deelen, P., Kristiansson, K., Mattsson, H., Nõukas, M., Sapkota, Y., Schick, U., Porcu, E., Rüeger, S., McDaid, A. F., Porteous, D., Winkler, T. W., Salvi, E., Shrine, N., Liu, X., Ang, W. Q., Zhang, W., Feitosa, M. F., Venturini, C., & 86 othersVan Der Most, P. J., Rosengren, A., Wood, A. R., Beaumont, R. N., Jones, S. E., Ruth, K. S., Yaghootkar, H., Tyrrell, J., Havulinna, A. S., Boers, H., Mägi, R., Kriebel, J., Müller-Nurasyid, M., Perola, M., Nieminen, M., Lokki, M. L., Kähönen, M., Viikari, J. S., Geller, F., Lahti, J., Palotie, A., Koponen, P., Lundqvist, A., Rissanen, H., Bottinger, E. P., Afaq, S., Wojczynski, M. K., Lenzini, P., Nolte, I. M., Sparsø, T., Schupf, N., Christensen, K., Perls, T. T., Newman, A. B., Werge, T., Snieder, H., Spector, T. D., Chambers, J. C., Koskinen, S., Melbye, M., Raitakari, O. T., Lehtimäki, T., Tobin, M. D., Wain, L. V., Sinisalo, J., Peters, A., Meitinger, T., Martin, N. G., Wray, N. R., Montgomery, G. W., Medland, S. E., Swertz, M. A., Vartiainen, E., Borodulin, K., Männistö, S., Murray, A., Bochud, M., Jacquemont, S., Rivadeneira, F., Hansen, T. F., Oldehinkel, A. J., Mangino, M., Province, M. A., Deloukas, P., Kooner, J. S., Freathy, R. M., Pennell, C., Feenstra, B., Strachan, D. P., Lettre, G., Hirschhorn, J., Cusi, D., Heid, I. M., Hayward, C., Männik, K., Beckmann, J. S., Loos, R. J. F., Nyholt, D. R., Metspalu, A., Eriksson, J. G., Weedon, M. N., Salomaa, V., Franke, L., Reymond, A., Frayling, T. M. & Kutalik, Z., Dec 1 2017, In: Nature communications. 8, 1, 744.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      43 Scopus citations

    • Genome- and CD4+ T-cell methylome-wide association study of circulating trimethylamine-N-oxide in the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN)

      Aslibekyan, S., Irvin, M. R., Hidalgo, B. A., Perry, R. T., Jeyarajah, E. J., Garcia, E., Shalaurova, I., Hopkins, P. N., Province, M. A., Tiwari, H. K., Ordovas, J. M., Absher, D. M. & Arnett, D. K., Jun 1 2017, In: Journal of Nutrition and Intermediary Metabolism. 8, p. 1-7 7 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      10 Scopus citations

    • Loss of Cardioprotective Effects at the ADAMTS7 Locus as a Result of Gene-Smoking Interactions

      Saleheen, D., Zhao, W., Young, R., Nelson, C. P., Ho, W., Ferguson, J. F., Rasheed, A., Ou, K., Nurnberg, S. T., Bauer, R. C., Goel, A., Do, R., Stewart, A. F. R., Hartiala, J., Zhang, W., Thorleifsson, G., Strawbridge, R. J., Sinisalo, J., Kanoni, S., Sedaghat, S., & 50 othersMarouli, E., Kristiansson, K., Zhao, J. H., Scott, R., Gauguier, D., Shah, S. H., Smith, A. V., Van Zuydam, N., Cox, A. J., Willenborg, C., Kessler, T., Zeng, L., Province, M. A., Ganna, A., Lind, L., Pedersen, N. L., White, C. C., Joensuu, A., Kleber, M. E., Hall, A. S., März, W., Salomaa, V., O'Donnell, C., Ingelsson, E., Feitosa, M. F., Erdmann, J., Bowden, D. W., Palmer, C. N. A., Gudnason, V., Faire, U. D., Zalloua, P., Wareham, N., Thompson, J. R., Kuulasmaa, K., Dedoussis, G., Perola, M., Dehghan, A., Chambers, J. C., Kooner, J., Allayee, H., Deloukas, P., McPherson, R., Stefansson, K., Schunkert, H., Kathiresan, S., Farrall, M., Marcel Frossard, P., Rader, D. J., Samani, N. J. & Reilly, M. P., Jun 13 2017, In: Circulation. 135, 24, p. 2336-2353 18 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      33 Scopus citations

    • New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

      behalf of the CHARGE EXOME BP, CHD Exome+, Exome BP, GoT2D:T2DGenes Consortia, The UK Biobank Cardio-Metabolic Traits Consortium Blood Pressure Working Group & The Understanding Society Scientific Group, Oct 1 2017, In: Circulation: Cardiovascular Genetics. 10, 5, e001778.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      39 Scopus citations

    • Sex Differences in Blood HDL-c, the Total Cholesterol/HDL-c Ratio, and Palmitoleic Acid are Not Associated with Variants in Common Candidate Genes

      Klingel, S. L., Roke, K., Hidalgo, B., Aslibekyan, S., Straka, R. J., An, P., Province, M. A., Hopkins, P. N., Arnett, D. K., Ordovas, J. M., Lai, C. Q. & Mutch, D. M., Dec 1 2017, In: Lipids. 52, 12, p. 969-980 12 p.

      Research output: Contribution to journal › Article › peer-review

      15 Scopus citations

    • Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms

      the eMERGE Consortium, the DIAGRAM Consortium, the MuTHER Consortium, SIGMA T2D Consortium, the DIAGRAM Consortium, the MuTHER Consortium, SIGMA T2D Consortium, the MuTHER Consortium, SIGMA T2D Consortium, SIGMA T2D Consortium, MEDIA Consortium, the FIND Consortium, the eMERGE Consortium, the DIAGRAM Consortium, the MuTHER Consortium, SIGMA T2D Consortium, the eMERGE Consortium, the DIAGRAM Consortium, the MuTHER Consortium & SIGMA T2D Consortium, Jun 29 2017, In: Cell. 170, 1, p. 199-212.e20

      Research output: Contribution to journal › Article › peer-review

      Open Access
      97 Scopus citations
    • 2016

      A Framework for Interpreting Type I Error Rates from a Product-Term Model of Interaction Applied to Quantitative Traits

      Rao, T. J. & Province, M. A., Feb 1 2016, In: Genetic Epidemiology. 40, 2, p. 144-153 10 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      7 Scopus citations

    • An Empirical Comparison of Joint and Stratified Frameworks for Studying G × E Interactions: Systolic Blood Pressure and Smoking in the CHARGE Gene-Lifestyle Interactions Working Group

      Sung, Y. J., Winkler, T. W., Manning, A. K., Aschard, H., Gudnason, V., Harris, T. B., Smith, A. V., Boerwinkle, E., Brown, M. R., Morrison, A. C., Fornage, M., Lin, L. A., Richard, M., Bartz, T. M., Psaty, B. M., Hayward, C., Polasek, O., Marten, J., Rudan, I., Feitosa, M. F., & 38 othersKraja, A. T., Province, M. A., Deng, X., Fisher, V. A., Zhou, Y., Bielak, L. F., Smith, J., Huffman, J. E., Padmanabhan, S., Smith, B. H., Ding, J., Liu, Y., Lohman, K., Bouchard, C., Rankinen, T., Rice, T. K., Arnett, D., Schwander, K., Guo, X., Palmas, W., Rotter, J. I., Alfred, T., Bottinger, E. P., Loos, R. J. F., Amin, N., Franco, O. H., van Duijn, C. M., Vojinovic, D., Chasman, D. I., Ridker, P. M., Rose, L. M., Kardia, S., Zhu, X., Rice, K., Borecki, I. B., Rao, D. C., Gauderman, W. J. & Cupples, L. A., Jul 1 2016, In: Genetic Epidemiology. 40, 5, p. 404-415 12 p.

      Research output: Contribution to journal › Article › peer-review

      15 Scopus citations

    • Assessment of postprandial triglycerides in clinical practice: Validation in a general population and coronary heart disease patients

      Perez-Martinez, P., Alcala-Diaz, J. F., Kabagambe, E. K., Garcia-Rios, A., Tsai, M. Y., Delgado-Lista, J., Kolovou, G., Straka, R. J., Gomez-Delgado, F., Hopkins, P. N., Marin, C., Borecki, I., Yubero-Serrano, E. M., Hixson, J. E., Camargo, A., Province, M. A., Lopez-Moreno, J., Rodriguez-Cantalejo, F., Tinahones, F. J., Mikhailidis, D. P., & 4 othersPerez-Jimenez, F., Arnett, D. K., Ordovas, J. M. & Lopez-Miranda, J., Sep 1 2016, In: Journal of Clinical Lipidology. 10, 5, p. 1163-1171 9 p.

      Research output: Contribution to journal › Article › peer-review

      20 Scopus citations

    • Candidate gene resequencing to identify rare, pedigree-specific variants influencing healthy aging phenotypes in the long life family study

      Druley, T. E., Wang, L., Lin, S. J., Lee, J. H., Zhang, Q., Daw, E. W., Abel, H. J., Chasnoff, S. E., Ramos, E. I., Levinson, B. T., Thyagarajan, B., Newman, A. B., Christensen, K., Mayeux, R. & Province, M. A., Apr 9 2016, In: BMC Geriatrics. 16, 1, 80.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      18 Scopus citations

    • Epigenome-wide association study of triglyceride postprandial responses to a high-fat dietary challenge

      Lai, C. Q., Wojczynski, M. K., Parnell, L. D., Hidalgo, B. A., Irvin, M. R., Aslibekyan, S., Province, M. A., Absher, D. M., Arnett, D. K. & Ordovás, J. M., 2016, In: Journal of lipid research. 57, 12, p. 2200-2207 8 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      27 Scopus citations

    • General Framework for Meta-Analysis of Haplotype Association Tests

      Wang, S., Zhao, J. H., An, P., Guo, X., Jensen, R. A., Marten, J., Huffman, J. E., Meidtner, K., Boeing, H., Campbell, A., Rice, K. M., Scott, R. A., Yao, J., Schulze, M. B., Wareham, N. J., Borecki, I. B., Province, M. A., Rotter, J. I., Hayward, C., Goodarzi, M. O., & 2 othersMeigs, J. B. & Dupuis, J., Apr 1 2016, In: Genetic Epidemiology. 40, 3, p. 244-252 9 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access

    • Genetic variants linked to education predict longevity

      Marioni, R. E., Ritchie, S. J., Joshi, P. K., Hagenaars, S. P., Okbay, A., Fischer, K., Adams, M. J., Hill, W. D., Davies, G., Nagy, R., Amador, C., Läll, K., Metspalu, A., Liewald, D. C., Campbell, A., Wilson, J. F., Hayward, C., Esko, T., Porteous, D. J., Gale, C. R., & 255 othersDeary, I. J., Okbay, A., Beauchamp, J. P., Fontana, M. A., Lee, J. J., Pers, T. H., Rietveld, C. A., Turley, P., Chen, G. B., Emilsson, V., Meddens, S. F., Oskarsson, S., Pickrell, J. K., Thom, K., Timshel, P., de Vlaming, R., Abdellaoui, A., Ahluwalia, T. S., Bacelis, J., Baumbach, C., Bjornsdottir, G., Brandsma, J. H., Concas, M. P., Derringer, J., Furlotte, N. A., Galesloot, T. E., Girotto, G., Gupta, R., Hall, L. M., Harris, S. E., Hofer, E., Horikoshi, M., Huffman, J. E., Kaasik, K., Kalafati, I. P., Karlsson, R., Kong, A., Lahti, J., van der Lee, S. J., de Leeuw, C., Lind, P. A., Lindgren, K. O., Liu, T., Mangino, M., Marten, J., Mihailov, E., Miller, M. B., van der Most, P. J., Oldmeadow, C., Payton, A., Pervjakova, N., Peyrot, W. J., Qian, Y., Raitakari, O., Rueedi, R., Salvi, E., Schmidt, B., Schraut, K. E., Shi, J., Smith, A. V., Poot, R. A., St Pourcain, B., Teumer, A., Thorleifsson, G., Verweij, N., Vuckovic, D., Wellmann, J., Westra, H. J., Yang, J., Zhao, W., Zhu, Z., Alizadeh, B. Z., Amin, N., Bakshi, A., Baumeister, S. E., Biino, G., Bønnelykke, K., Boyle, P. A., Campbell, H., Cappuccio, F. P., Davies, G., De Neve, J. E., Deloukas, P., Demuth, I., Ding, J., Eibich, P., Eisele, L., Eklund, N., Evans, D. M., Faul, J. D., Feitosa, M. F., Forstner, A. J., Gandin, I., Gunnarsson, B., Halldórsson, B. V., Harris, T. B., Heath, A. C., Hocking, L. J., Holliday, E. G., Homuth, G., Horan, M. A., Hottenga, J. J., de Jager, P. L., Joshi, P. K., Jugessur, A., Kaakinen, M. A., Kähönen, M., Kanoni, S., Keltigangas-Järvinen, L., Kiemeney, L. A., Kolcic, I., Koskinen, S., Kraja, A. T., Kroh, M., Kutalik, Z., Latvala, A., Launer, L. J., Lebreton, M. P., Levinson, D. F., Lichtenstein, P., Lichtner, P., Liewald, D. C., Loukola, A., Madden, P. A., Mägi, R., Mäki-Opas, T., Marioni, R. E., Marques-Vidal, P., Meddens, G. A., McMahon, G., Meisinger, C., Meitinger, T., Milaneschi, Y., Milani, L., Montgomery, G. W., Myhre, R., Nelson, C. P., Nyholt, D. R., Ollier, W. E., Palotie, A., Paternoster, L., Pedersen, N. L., Petrovic, K. E., Porteous, D. J., Räikkönen, K., Ring, S. M., Robino, A., Rostapshova, O., Rudan, I., Rustichini, A., Salomaa, V., Sanders, A. R., Sarin, A. P., Schmidt, H., Scott, R. J., Smith, B. H., Smith, J. A., Staessen, J. A., Steinhagen-Thiessen, E., Strauch, K., Terracciano, A., Ulivi, S., Vaccargiu, S., Quaye, L., van Rooij, F. J., Venturini, C., Vinkhuyzen, A. A., Völker, U., Völzke, H., Vonk, J. M., Vozzi, D., Waage, J., Ware, E. B., Willemsen, G., Attia, J. R., Bennett, D. A., Berger, K., Bertram, L., Bisgaard, H., Boomsma, D. I., Borecki, I. B., Bultmann, U., Chabris, C. F., Cucca, F., Cusi, D., Deary, I. J., Dedoussis, G. V., van Duijn, C. M., Eriksson, J. G., Franke, B., Franke, L., Gasparini, P., Gejman, P. V., Gieger, C., Grabe, H. J., Gratten, J., Groenen, P. J., Gudnason, V., van der Harst, P., Hayward, C., Hinds, D. A., Hoffmann, W., Hypponen, E., Iacono, W. G., Jacobsson, B., Järvelin, M. R., Jöckel, K. H., Kaprio, J., Kardia, S. L., Lehtimäki, T., Lehrer, S. F., Magnusson, P. K., Martin, N. G., McGue, M., Metspalu, A., Pendleton, N., Penninx, B. W., Perola, M., Pirastu, N., Pirastu, M., Polasek, O., Posthuma, D., Power, C., Province, M. A., Samani, N. J., Schlessinger, D., Schmidt, R., Sørensen, T. I., Spector, T. D., Stefansson, K., Thorsteinsdottir, U., Thurik, A. R., Timpson, N. J., Tiemeier, H., Tung, J. Y., Uitterlinden, A. G., Vitart, V., Vollenweider, P., Weir, D. R., Wilson, J. F., Wright, A. F., Conley, D. C., Krueger, R. F., Smith, G. D., Hofman, A., Laibson, D. I., Medland, S. E., Meyer, M. N., Yang, J., Johannesson, M., Visscher, P. M., Esko, T., Koellinger, P. D., Cesarini, D. & Benjamin, D. J., Nov 22 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 47, p. 13366-13371 6 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      45 Scopus citations

    • Genome-wide association study identifies 74 loci associated with educational attainment

      Okbay, A., Beauchamp, J. P., Fontana, M. A., Lee, J. J., Pers, T. H., Rietveld, C. A., Turley, P., Chen, G. B., Emilsson, V., Meddens, S. F. W., Oskarsson, S., Pickrell, J. K., Thom, K., Timshel, P., De Vlaming, R., Abdellaoui, A., Ahluwalia, T. S., Bacelis, J., Baumbach, C., Bjornsdottir, G., & 235 othersBrandsma, J. H., Pina Concas, M., Derringer, J., Furlotte, N. A., Galesloot, T. E., Girotto, G., Gupta, R., Hall, L. M., Harris, S. E., Hofer, E., Horikoshi, M., Huffman, J. E., Kaasik, K., Kalafati, I. P., Karlsson, R., Kong, A., Lahti, J., Van Der Lee, S. J., Deleeuw, C., Lind, P. A., Lindgren, K. O., Liu, T., Mangino, M., Marten, J., Mihailov, E., Miller, M. B., Van Der Most, P. J., Oldmeadow, C., Payton, A., Pervjakova, N., Peyrot, W. J., Qian, Y., Raitakari, O., Rueedi, R., Salvi, E., Schmidt, B., Schraut, K. E., Shi, J., Smith, A. V., Poot, R. A., St Pourcain, B., Teumer, A., Thorleifsson, G., Verweij, N., Vuckovic, D., Wellmann, J., Westra, H. J., Yang, J., Zhao, W., Zhu, Z., Alizadeh, B. Z., Amin, N., Bakshi, A., Baumeister, S. E., Biino, G., Bønnelykke, K., Boyle, P. A., Campbell, H., Cappuccio, F. P., Davies, G., De Neve, J. E., Deloukas, P., Demuth, I., Ding, J., Eibich, P., Eisele, L., Eklund, N., Evans, D. M., Faul, J. D., Feitosa, M. F., Forstner, A. J., Gandin, I., Gunnarsson, B., Halldórsson, B. V., Harris, T. B., Holliday, E. G., Heath, A. C., Hocking, L. J., Homuth, G., Horan, M. A., Hottenga, J. J., De Jager, P. L., Joshi, P. K., Jugessur, A., Kaakinen, M. A., Kähönen, M., Kanoni, S., Keltigangas-Järvinen, L., Kiemeney, L. A. L. M., Kolcic, I., Koskinen, S., Kraja, A. T., Kroh, M., Kutalik, Z., Latvala, A., Launer, L. J., Lebreton, M. P., Levinson, D. F., Lichtenstein, P., Lichtner, P., Liewald, D. C. M., Loukola, A., Madden, P. A., Mägi, R., Mäki-Opas, T., Marioni, R. E., Marques-Vidal, P., Meddens, G. A., Mcmahon, G., Meisinger, C., Meitinger, T., Milaneschi, Y., Milani, L., Montgomery, G. W., Myhre, R., Nelson, C. P., Nyholt, D. R., Ollier, W. E. R., Palotie, A., Paternoster, L., Pedersen, N. L., Petrovic, K. E., Porteous, D. J., Raïkkönen, K., Ring, S. M., Robino, A., Rostapshova, O., Rudan, I., Rustichini, A., Salomaa, V., Sanders, A. R., Sarin, A. P., Schmidt, H., Scott, R. J., Smith, B. H., Smith, J. A., Staessen, J. A., Steinhagen-Thiessen, E., Strauch, K., Terracciano, A., Tobin, M. D., Ulivi, S., Vaccargiu, S., Quaye, L., Van Rooij, F. J. A., Venturini, C., Vinkhuyzen, A. A. E., Völker, U., Völzke, H., Vonk, J. M., Vozzi, D., Waage, J., Ware, E. B., Willemsen, G., Attia, J. R., Bennett, D. A., Berger, K., Bertram, L., Bisgaard, H., Boomsma, D. I., Borecki, I. B., Bültmann, U., Chabris, C. F., Cucca, F., Cusi, D., Deary, I. J., Dedoussis, G. V., Van Duijn, C. M., Eriksson, J. G., Franke, B., Franke, L., Gasparini, P., Gejman, P. V., Gieger, C., Grabe, H. J., Gratten, J., Groenen, P. J. F., Gudnason, V., Van Der Harst, P., Hayward, C., Hinds, D. A., Hoffmann, W., Hyppönen, E., Iacono, W. G., Jacobsson, B., Järvelin, M. R., Jöckel, K. H., Kaprio, J., Kardia, S. L. R., Lehtimäki, T., Lehrer, S. F., Magnusson, P. K. E., Martin, N. G., Mcgue, M., Metspalu, A., Pendleton, N., Penninx, B. W. J. H., Perola, M., Pirastu, N., Pirastu, M., Polasek, O., Posthuma, D., Power, C., Province, M. A., Samani, N. J., Schlessinger, D., Schmidt, R., Sørensen, T. I. A., Spector, T. D., Stefansson, K., Thorsteinsdottir, U., Thurik, A. R., Timpson, N. J., Tiemeier, H., Tung, J. Y., Uitterlinden, A. G., Vitart, V., Vollenweider, P., Weir, D. R., Wilson, J. F., Wright, A. F., Conley, D. C., Krueger, R. F., Davey Smith, G., Hofman, A., Laibson, D. I., Medland, S. E., Meyer, M. N., Yang, J., Johannesson, M., Visscher, P. M., Esko, T., Koellinger, P. D., Cesarini, D. & Benjamin, D. J., May 11 2016, In: Nature. 533, 7604, p. 539-542 4 p.

      Research output: Contribution to journal › Article › peer-review

      692 Scopus citations

    • Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis

      Natarajan, P., Bis, J. C., Bielak, L. F., Cox, A. J., Dörr, M., Feitosa, M. F., Franceschini, N., Guo, X., Hwang, S. J., Isaacs, A., Jhun, M. A., Kavousi, M., Li-Gao, R., Lyytikäinen, L. P., Marioni, R. E., Schminke, U., Stitziel, N. O., Tada, H., Van Setten, J., Smith, A. V., & 80 othersVojinovic, D., Yanek, L. R., Yao, J., Yerges-Armstrong, L. M., Amin, N., Baber, U., Borecki, I. B., Carr, J. J., Chen, Y. D. I., Cupples, L. A., De Jong, P. A., De Koning, H., De Vos, B. D., Demirkan, A., Fuster, V., Franco, O. H., Goodarzi, M. O., Harris, T. B., Heckbert, S. R., Heiss, G., Hoffmann, U., Hofman, A., Išgum, I., Jukema, J. W., Kähönen, M., Kardia, S. L. R., Kral, B. G., Launer, L. J., Massaro, J., Mehran, R., Mitchell, B. D., Mosley, T. H., De Mutsert, R., Newman, A. B., Nguyen, K. D., North, K. E., O'Connell, J. R., Oudkerk, M., Pankow, J. S., Peloso, G. M., Post, W., Province, M. A., Raffield, L. M., Raitakari, O. T., Reilly, D. F., Rivadeneira, F., Rosendaal, F., Sartori, S., Taylor, K. D., Teumer, A., Trompet, S., Turner, S. T., Uitterlinden, A. G., Vaidya, D., Van Der Lugt, A., Völker, U., Wardlaw, J. M., Wassel, C. L., Weiss, S., Wojczynski, M. K., Becker, D. M., Becker, L. C., Boerwinkle, E., Bowden, D. W., Deary, I. J., Dehghan, A., Felix, S. B., Gudnason, V., Lehtimäki, T., Mathias, R., Mook-Kanamori, D. O., Psaty, B. M., Rader, D. J., Rotter, J. I., Wilson, J. G., Van Duijn, C. M., Völzke, H., Kathiresan, S., Peyser, P. A. & O'Donnell, C. J., Dec 1 2016, In: Circulation: Cardiovascular Genetics. 9, 6, p. 511-520 10 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      34 Scopus citations

    • Persistent and newly developed chronic bronchitis are associated with worse outcomes in chronic obstructive pulmonary disease

      the COPDGene Investigators, Jul 1 2016, In: Annals of the American Thoracic Society. 13, 7, p. 1016-1025 10 p.

      Research output: Contribution to journal › Article › peer-review

      30 Scopus citations

    • Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin

      Liu, C. T., Raghavan, S., Maruthur, N., Kabagambe, E. K., Hong, J., Ng, M. C. Y., Hivert, M. F., Lu, Y., An, P., Bentley, A. R., Drolet, A. M., Gaulton, K. J., Guo, X., Armstrong, L. L., Irvin, M. R., Li, M., Lipovich, L., Rybin, D. V., Taylor, K. D., Agyemang, C., & 95 othersPalmer, N. D., Cade, B. E., Chen, W. M., Dauriz, M., Delaney, J. A. C., Edwards, T. L., Evans, D. S., Evans, M. K., Lange, L. A., Leong, A., Liu, J., Liu, Y., Nayak, U., Patel, S. R., Porneala, B. C., Rasmussen-Torvik, L. J., Snijder, M. B., Stallings, S. C., Tanaka, T., Yanek, L. R., Zhao, W., Becker, D. M., Bielak, L. F., Biggs, M. L., Bottinger, E. P., Bowden, D. W., Chen, G., Correa, A., Couper, D. J., Crawford, D. C., Cushman, M., Eicher, J. D., Fornage, M., Franceschini, N., Fu, Y. P., Goodarzi, M. O., Gottesman, O., Hara, K., Harris, T. B., Jensen, R. A., Johnson, A. D., Jhun, M. A., Karter, A. J., Keller, M. F., Kho, A. N., Kizer, J. R., Krauss, R. M., Langefeld, C. D., Li, X., Liang, J., Liu, S., Lowe, W. L., Mosley, T. H., North, K. E., Pacheco, J. A., Peyser, P. A., Patrick, A. L., Rice, K. M., Selvin, E., Sims, M., Smith, J. A., Tajuddin, S. M., Vaidya, D., Wren, M. P., Yao, J., Zhu, X., Ziegler, J. T., Zmuda, J. M., Zonderman, A. B., Zwinderman, A. H., Adeyemo, A., Boerwinkle, E., Ferrucci, L., Hayes, M. G., Kardia, S. L. R., Miljkovic, I., Pankow, J. S., Rotimi, C. N., Sale, M. M., Wagenknecht, L. E., Arnett, D. K., Chen, Y. D. I., Nalls, M. A., Province, M. A., Kao, W. H. L., Siscovick, D. S., Psaty, B. M., Wilson, J. G., Loos, R. J. F., Dupuis, J., Rich, S. S., Florez, J. C., Rotter, J. I., Morris, A. P. & Meigs, J. B., Jul 7 2016, In: American journal of human genetics. 99, 1, p. 56-75 20 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      38 Scopus citations
    • 2015

      Admixture mapping of coronary artery calcification in African Americans from the NHLBI family heart study

      Gomez, F., Wang, L., Abel, H., Zhang, Q., Province, M. A. & Borecki, I. B., Apr 23 2015, In: BMC genetics. 16, 1, 42.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      8 Scopus citations

    • Consumption of meat is associated with higher fasting glucose and insulin concentrations regardless of glucose and insulin genetic risk scores: A meta-analysis of 50,345 Caucasians

      Fretts, A. M., Follis, J. L., Nettleton, J. A., Lemaitre, R. N., Ngwa, J. S., Wojczynski, M. K., Kalafati, I. P., Varga, T. V., Frazier-Wood, A. C., Houston, D. K., Lahti, J., Ericson, U., Van Den Hooven, E. H., Mikkilä, V., Kiefte-De Jong, J. C., Mozaffarian, D., Rice, K., Renström, F., North, K. E., McKeown, N. M., & 42 othersFeitosa, M. F., Kanoni, S., Smith, C. E., Garcia, M. E., Tiainen, A. M., Sonestedt, E., Manichaikul, A., Van Rooij, F. J. A., Dimitriou, M., Raitakari, O., Pankow, J. S., Djoussé, L., Province, M. A., Hu, F. B., Lai, C. Q., Keller, M. F., Perälä, M. M., Rotter, J. I., Hofman, A., Graff, M., Kähönen, M., Mukamal, K., Johansson, I., Ordovas, J. M., Liu, Y., Männistö, S., Uitterlinden, A. G., Deloukas, P., Seppälä, I., Psaty, B. M., Cupples, L. A., Borecki, I. B., Franks, P. W., Arnett, D. K., Nalls, M. A., Eriksson, J. G., Orho-Melander, M., Franco, O. H., Lehtimäki, T., Dedoussis, G. V., Meigs, J. B. & Siscovick, D. S., Nov 1 2015, In: American Journal of Clinical Nutrition. 102, 5, p. 1266-1278 13 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      53 Scopus citations

    • Genetic studies of body mass index yield new insights for obesity biology

      Lifelines Cohort Study & ADIPOGen Consortium; AGEN-BMI Working Group; CARDIOGRAMplusC4D Consortium; CKDGen Consortium; GLGC; ICBP; MAGIC Investigators; MuTHER Consortium; MIGen Consortium; PAGE Consortium; ReproGen Consortium; GENIE Consortium; International Endogene Consortium, Feb 12 2015, In: Nature. 518, 7538, p. 197-206 10 p.

      Research output: Contribution to journal › Article › peer-review

      2661 Scopus citations

    • Genome-wide association study and linkage analysis of the healthy aging index

      Minster, R. L., Sanders, J. L., Singh, J., Kammerer, C. M., Barmada, M. M., Matteini, A. M., Zhang, Q., Wojczynski, M. K., Daw, E. W., Brody, J. A., Arnold, A. M., Lunetta, K. L., Murabito, J. M., Christensen, K., Perls, T. T., Province, M. A. & Newman, A. B., Aug 2015, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 70, 8, p. 1003-1008 6 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      15 Scopus citations

    • Genome-wide association study of triglyceride response to a high-fat meal among participants of the NHLBI Genetics of Lipid Lowering Drugs and Diet Network (GOLDN)

      Wojczynski, M. K., Parnell, L. D., Pollin, T. I., Lai, C. Q., Feitosa, M. F., O'Connell, J. R., Frazier-Wood, A. C., Gibson, Q., Aslibekyan, S., Ryan, K. A., Province, M. A., Tiwari, H. K., Ordovas, J. M., Shuldiner, A. R., Arnett, D. K. & Borecki, I. B., Oct 1 2015, In: Metabolism: clinical and experimental. 64, 10, p. 1359-1371 13 p.

      Research output: Contribution to journal › Article › peer-review

      27 Scopus citations

    • Heritability of telomere length in a study of long-lived families

      Honig, L. S., Kang, M. S., Cheng, R., Eckfeldt, J. H., Thyagarajan, B., Leiendecker-Foster, C., Province, M. A., Sanders, J. L., Perls, T., Christensen, K., Lee, J. H., Mayeux, R. & Schupf, N., Oct 1 2015, In: Neurobiology of Aging. 36, 10, p. 2785-2790 6 p.

      Research output: Contribution to journal › Article › peer-review

      54 Scopus citations

    • Leukocyte Telomere Length and Coronary Artery Calcium

      Hunt, S. C., Kimura, M., Hopkins, P. N., Carr, J. J., Heiss, G., Province, M. A. & Aviv, A., Jul 15 2015, In: American Journal of Cardiology. 116, 2, p. 214-218 5 p., 21114.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      34 Scopus citations

    • Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

      Wessel, J., Chu, A. Y., Willems, S. M., Wang, S., Yaghootkar, H., Brody, J. A., Dauriz, M., Hivert, M. F., Raghavan, S., Lipovich, L., Hidalgo, B., Fox, K., Huffman, J. E., An, P., Lu, Y., Rasmussen-Torvik, L. J., Grarup, N., Ehm, M. G., Li, L., Baldridge, A. S., & 184 othersStančáková, A., Abrol, R., Besse, C., Boland, A., Bork-Jensen, J., Fornage, M., Freitag, D. F., Garcia, M. E., Guo, X., Hara, K., Isaacs, A., Jakobsdottir, J., Lange, L. A., Layton, J. C., Li, M., Hua Zhao, J., Meidtner, K., Morrison, A. C., Nalls, M. A., Peters, M. J., Sabater-Lleal, M., Schurmann, C., Silveira, A., Smith, A. V., Southam, L., Stoiber, M. H., Strawbridge, R. J., Taylor, K. D., Varga, T. V., Allin, K. H., Amin, N., Aponte, J. L., Aung, T., Barbieri, C., Bihlmeyer, N. A., Boehnke, M., Bombieri, C., Bowden, D. W., Burns, S. M., Chen, Y., Chen, Y. D., Cheng, C. Y., Correa, A., Czajkowski, J., Dehghan, A., Ehret, G. B., Eiriksdottir, G., Escher, S. A., Farmaki, A. E., Frånberg, M., Gambaro, G., Giulianini, F., Goddard, W. A., Goel, A., Gottesman, O., Grove, M. L., Gustafsson, S., Hai, Y., Hallmans, G., Heo, J., Hoffmann, P., Ikram, M. K., Jensen, R. A., Jørgensen, M. E., Jørgensen, T., Karaleftheri, M., Khor, C. C., Kirkpatrick, A., Kraja, A. T., Kuusisto, J., Lange, E. M., Lee, I. T., Lee, W. J., Leong, A., Liao, J., Liu, C., Liu, Y., Lindgren, C. M., Linneberg, A., Malerba, G., Mamakou, V., Marouli, E., Maruthur, N. M., Matchan, A., McKean-Cowdin, R., McLeod, O., Metcalf, G. A., Mohlke, K. L., Muzny, D. M., Ntalla, I., Palmer, N. D., Pasko, D., Peter, A., Rayner, N. W., Renström, F., Rice, K., Sala, C. F., Sennblad, B., Serafetinidis, I., Smith, J. A., Soranzo, N., Speliotes, E. K., Stahl, E. A., Stirrups, K., Tentolouris, N., Thanopoulou, A., Torres, M., Traglia, M., Tsafantakis, E., Javad, S., Yanek, L. R., Zengini, E., Becker, D. M., Bis, J. C., Brown, J. B., Adrienne Cupples, L., Hansen, T., Ingelsson, E., Karter, A. J., Lorenzo, C., Mathias, R. A., Norris, J. M., Peloso, G. M., Sheu, W. H. H., Toniolo, D., Vaidya, D., Varma, R., Wagenknecht, L. E., Boeing, H., Bottinger, E. P., Dedoussis, G., Deloukas, P., Ferrannini, E., Franco, O. H., Franks, P. W., Gibbs, R. A., Gudnason, V., Hamsten, A., Harris, T. B., Hattersley, A. T., Hayward, C., Hofman, A., Jansson, J. H., Langenberg, C., Launer, L. J., Levy, D., Oostra, B. A., O'Donnell, C. J., O'Rahilly, S., Padmanabhan, S., Pankow, J. S., Polasek, O., Province, M. A., Rich, S. S., Ridker, P. M., Rudan, I., Schulze, M. B., Smith, B. H., Uitterlinden, A. G., Walker, M., Watkins, H., Wong, T. Y., Zeggini, E., Laakso, M., Borecki, I. B., Chasman, D. I., Pedersen, O., Psaty, B. M., Shyong Tai, E., Van Duijn, C. M., Wareham, N. J., Waterworth, D. M., Boerwinkle, E., Linda Kao, W. H., Florez, J. C., Loos, R. J. F., Wilson, J. G., Frayling, T. M., Siscovick, D. S., Dupuis, J., Rotter, J. I., Meigs, J. B., Scott, R. A. & Goodarzi, M. O., Feb 2015, In: Nature communications. 6, 5897.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      141 Scopus citations

    • New genetic loci link adipose and insulin biology to body fat distribution

      ADIPOGen Consortium; CARDIOGRAMplusC4D Consortium; CKDGen Consortium; GEFOS Consortium; GENIE Consortium; GLGC; ICBP; International Endogene Consortium; LifeLines Cohort Study; MAGIC Investigators; MuTHER Consortium; PAGE Consortium; ReproGen Consortium, Feb 12 2015, In: Nature. 518, 7538, p. 187-196 10 p.

      Research output: Contribution to journal › Article › peer-review

      936 Scopus citations

    • Selection of models for the analysis of risk-factor trees: Leveraging biological knowledge to mine large sets of risk factors with application to microbiome data

      Zhang, Q., Abel, H., Wells, A., Lenzini, P., Gomez, F., Province, M. A., Templeton, A. A., Weinstock, G. M., Salzman, N. H. & Borecki, I. B., May 15 2015, In: Bioinformatics. 31, 10, p. 1607-1613 7 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      9 Scopus citations

    • Trade-Offs in the Effects of the Apolipoprotein E Polymorphism on Risks of Diseases of the Heart, Cancer, and Neurodegenerative Disorders: Insights on Mechanisms from the Long Life Family Study

      Kulminski, A. M., Arbeev, K. G., Culminskaya, I., Ukraintseva, S. V., Stallard, E., Province, M. A. & Yashin, A. I., Apr 1 2015, In: Rejuvenation Research. 18, 2, p. 128-135 8 p.

      Research output: Contribution to journal › Article › peer-review

      12 Scopus citations