Michael Province

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Michael Province

Professor of Genetics, Professor of Biostatistics

 https://orcid.org/0000-0001-6102-774X

    Willing to Mentor

    Available to Mentor:

    PhD/MSTP Students

    • 46332
      Citations
    1980 …2025

    Research activity per year

    Search results

    • 2020

      Leukocyte Telomere Length Is Unrelated to Cognitive Performance among Non-Demented and Demented Persons: An Examination of Long Life Family Study Participants

      Ashrafi, A., Cosentino, S., Kang, M. S., Lee, J. H., Schupf, N., Andersen, S. L., Christensen, K., Province, M. A., Thyagarajan, B., Zmuda, J. M. & Honig, L. S., Oct 1 2020, In: Journal of the International Neuropsychological Society. 26, 9, p. 906-917 12 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      8 Scopus citations

    • Mechanisms underlying familial aggregation of exceptional health and survival: A three-generation cohort study

      Christensen, K., Wojczynski, M. K., Pedersen, J. K., Larsen, L. A., Kløjgaard, S., Skytthe, A., McGue, M., Vaupel, J. W. & Province, M. A., Oct 1 2020, In: Aging Cell. 19, 10, e13228.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      13 Scopus citations

    • Role of Rare and Low-Frequency Variants in Gene-Alcohol Interactions on Plasma Lipid Levels

      Wang, Z., Chen, H., Bartz, T. M., Bielak, L. F., Chasman, D. I., Feitosa, M. F., Franceschini, N., Guo, X., Lim, E., Noordam, R., Richard, M. A., Wang, H., Cade, B., Cupples, L. A., De Vries, P. S., Giulanini, F., Lee, J., Lemaitre, R. N., Martin, L. W. & Reiner, A. P. & 20 others, Rich, S. S., Schreiner, P. J., Sidney, S., Sitlani, C. M., Smith, J. A., Willems Van Dijk, K., Yao, J., Zhao, W., Fornage, M., Kardia, S. L. R., Kooperberg, C., Liu, C. T., Mook-Kanamori, D. O., Province, M. A., Psaty, B. M., Redline, S., Ridker, P. M., Rotter, J. I., Boerwinkle, E. & Morrison, A. C., Aug 1 2020, In: Circulation: Genomic and Precision Medicine. 13, 4, p. E002772

      Research output: Contribution to journal › Article › peer-review

      Open Access
      11 Scopus citations

    • Salivary AMY1 Copy Number Variation Modifies Age-Related Type 2 Diabetes Risk

      Liu, Y., Smith, C. E., Parnell, L. D., Lee, Y. C., An, P., Straka, R. J., Tiwari, H. K., Wood, A. C., Kabagambe, E. K., Hidalgo, B., Hopkins, P. N., Province, M. A., Arnett, D. K., Tucker, K. L., Ordovas, J. M. & Lai, C. Q., May 1 2020, In: Clinical chemistry. 66, 5, p. 718-726 9 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      8 Scopus citations

    • Smoking-by-genotype interaction in type 2 diabetes risk and fasting glucose

      Wu, P., Rybin, D., Bielak, L. F., Feitosa, M. F., Franceschini, N., Li, Y., Lu, Y., Marten, J., Musani, S. K., Noordam, R., Raghavan, S., Rose, L. M., Schwander, K., Smith, A. V., Tajuddin, S. M., Vojinovic, D., Amin, N., Arnett, D. K., Bottinger, E. P. & Demirkan, A. & 38 others, Florez, J. C., Ghanbari, M., Harris, T. B., Launer, L. J., Liu, J., Liu, J., Mook-Kanamori, D. O., Murray, A. D., Nalls, M. A., Peyser, P. A., Uitterlinden, A. G., Voortman, T., Bouchard, C., Chasman, D., Correa, A., de Mutsert, R., Evans, M. K., Gudnason, V., Hayward, C., Kao, L., Kardia, S. L. R., Kooperberg, C., Loos, R. J. F., Province, M. M., Rankinen, T., Redline, S., Ridker, P. M., Rotter, J. I., Siscovick, D., Smith, B. H., van Duijn, C., Zonderman, A. B., Rao, D. C., Wilson, J. G., Dupuis, J., Meigs, J. B., Liu, C. T. & Vassy, J. L., May 2020, In: PloS one. 15, 5, e0230815.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      11 Scopus citations
    • 2019

      A catalog of genetic loci associated with kidney function from analyses of a million individuals

      Lifelines Cohort Study & V. A. Million Veteran Program, Jun 1 2019, In: Nature Genetics. 51, 6, p. 957-972 16 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      535 Scopus citations

    • A meta-analysis of genome-wide association studies identifies multiple longevity genes

      Deelen, J., Evans, D. S., Arking, D. E., Tesi, N., Nygaard, M., Liu, X., Wojczynski, M. K., Biggs, M. L., van der Spek, A., Atzmon, G., Ware, E. B., Sarnowski, C., Smith, A. V., Seppälä, I., Cordell, H. J., Dose, J., Amin, N., Arnold, A. M., Ayers, K. L. & Barzilai, N. & 64 others, Becker, E. J., Beekman, M., Blanché, H., Christensen, K., Christiansen, L., Collerton, J. C., Cubaynes, S., Cummings, S. R., Davies, K., Debrabant, B., Deleuze, J. F., Duncan, R., Faul, J. D., Franceschi, C., Galan, P., Gudnason, V., Harris, T. B., Huisman, M., Hurme, M. A., Jagger, C., Jansen, I., Jylhä, M., Kähönen, M., Karasik, D., Kardia, S. L. R., Kingston, A., Kirkwood, T. B. L., Launer, L. J., Lehtimäki, T., Lieb, W., Lyytikäinen, L. P., Martin-Ruiz, C., Min, J., Nebel, A., Newman, A. B., Nie, C., Nohr, E. A., Orwoll, E. S., Perls, T. T., Province, M. A., Psaty, B. M., Raitakari, O. T., Reinders, M. J. T., Robine, J. M., Rotter, J. I., Sebastiani, P., Smith, J., Sørensen, T. I. A., Taylor, K. D., Uitterlinden, A. G., van der Flier, W., van der Lee, S. J., van Duijn, C. M., van Heemst, D., Vaupel, J. W., Weir, D., Ye, K., Zeng, Y., Zheng, W., Holstege, H., Kiel, D. P., Lunetta, K. L., Slagboom, P. E. & Murabito, J. M., Dec 1 2019, In: Nature communications. 10, 1, 3669.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      229 Scopus citations

    • A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

      Sung, Y. J., De Las Fuentes, L., Winkler, T. W., Chasman, D. I., Bentley, A. R., Kraja, A. T., Ntalla, I., Warren, H. R., Guo, X., Schwander, K., Manning, A. K., Brown, M. R., Aschard, H., Feitosa, M. F., Franceschini, N., Lu, Y., Cheng, C. Y., Sim, X., Vojinovic, D. & Marten, J. & 261 others, Musani, S. K., Kilpeläinen, T. O., Richard, M. A., Aslibekyan, S., Bartz, T. M., Dorajoo, R., Li, C., Liu, Y., Rankinen, T., Smith, A. V., Tajuddin, S. M., Tayo, B. O., Zhao, W., Zhou, Y., Matoba, N., Sofer, T., Alver, M., Amini, M., Boissel, M., Chai, J. F., Chen, X., Divers, J., Gandin, I., Gao, C., Giulianini, F., Goel, A., Harris, S. E., Hartwig, F. P., He, M., Horimoto, A. R. V. R., Hsu, F. C., Jackson, A. U., Kammerer, C. M., Kasturiratne, A., Komulainen, P., Kühnel, B., Leander, K., Lee, W. J., Lin, K. H., Luan, J., Lyytikäinen, L. P., McKenzie, C. A., Nelson, C. P., Noordam, R., Scott, R. A., Sheu, W. H. H., Stančáková, A., Takeuchi, F., Van Der Most, P. J., Varga, T. V., Waken, R. J., Wang, H., Wang, Y., Ware, E. B., Weiss, S., Wen, W., Yanek, L. R., Zhang, W., Zhao, J. H., Afaq, S., Alfred, T., Amin, N., Arking, D. E., Aung, T., Barr, R. G., Bielak, L. F., Boerwinkle, E., Bottinger, E. P., Braund, P. S., Brody, J. A., Broeckel, U., Cade, B., Campbell, A., Canouil, M., Chakravarti, A., Cocca, M., Collins, F. S., Connell, J. M., De Mutsert, R., De Silva, H. J., Dörr, M., Duan, Q., Eaton, C. B., Ehret, G., Evangelou, E., Faul, J. D., Forouhi, N. G., Franco, O. H., Friedlander, Y., Gao, H., Gigante, B., Gu, C. C., Gupta, P., Hagenaars, S. P., Harris, T. B., He, J., Heikkinen, S., Heng, C. K., Hofman, A., Howard, B. V., Hunt, S. C., Irvin, M. R., Jia, Y., Katsuya, T., Kaufman, J., Kerrison, N. D., Khor, C. C., Koh, W. P., Koistinen, H. A., Kooperberg, C. B., Krieger, J. E., Kubo, M., Kutalik, Z., Kuusisto, J., Lakka, T. A., Langefeld, C. D., Langenberg, C., Launer, L. J., Lee, J. H., Lehne, B., Levy, D., Lewis, C. E., Li, Y., Lim, S. H., Liu, C. T., Liu, J., Liu, J., Liu, Y., Loh, M., Lohman, K. K., Louie, T., Mägi, R., Matsuda, K., Meitinger, T., Metspalu, A., Milani, L., Momozawa, Y., Thomas, T. H., Nalls, M. A., Nasri, U., O'Connell, J. R., Ogunniyi, A., Palmas, W. R., Palmer, N. D., Pankow, J. S., Pedersen, N. L., Peters, A., Peyser, P. A., Polasek, O., Porteous, D., Raitakari, O. T., Renström, F., Rice, T. K., Ridker, P. M., Robino, A., Robinson, J. G., Rose, L. M., Rudan, I., Sabanayagam, C., Salako, B. L., Sandow, K., Schmidt, C. O., Schreiner, P. J., Scott, W. R., Sever, P., Sims, M., Sitlani, C. M., Smith, B. H., Smith, J. A., Snieder, H., Starr, J. M., Strauch, K., Tang, H., Taylor, K. D., Teo, Y. Y., Tham, Y. C., Uitterlinden, A. G., Waldenberger, M., Wang, L., Wang, Y. X., Wei, W. B., Wilson, G., Wojczynski, M. K., Xiang, Y. B., Yao, J., Yuan, J. M., Zonderman, A. B., Becker, D. M., Boehnke, M., Bowden, D. W., Chambers, J. C., Chen, Y. D. I., Weir, D. R., De Faire, U., Deary, I. J., Esko, T., Farrall, M., Forrester, T., Freedman, B. I., Froguel, P., Gasparini, P., Gieger, C., Horta, B. L., Hung, Y. J., Jonas, J. B., Kato, N., Kooner, J. S., Laakso, M., Lehtimäki, T., Liang, K. W., Magnusson, P. K. E., Oldehinkel, A. J., Pereira, A. C., Perls, T., Rauramaa, R., Redline, S., Rettig, R., Samani, N. J., Scott, J., Shu, X. O., Van Der Harst, P., Wagenknecht, L. E., Wareham, N. J., Watkins, H., Wickremasinghe, A. R., Wu, T., Kamatani, Y., Laurie, C. C., Bouchard, C., Cooper, R. S., Evans, M. K., Gudnason, V., Hixson, J., Kardia, S. L. R., Kritchevsky, S. B., Psaty, B. M., Van Dam, R. M., Arnett, D. K., Mook-Kanamori, D. O., Fornage, M., Fox, E. R., Hayward, C., Van Duijn, C. M., Tai, E. S., Wong, T. Y., Loos, R. J. F., Reiner, A. P., Rotimi, C. N., Bierut, L. J., Zhu, X., Cupples, L. A., Province, M. A., Rotter, J. I., Franks, P. W., Rice, K., Elliott, P., Caulfield, M. J., Gauderman, W. J., Munroe, P. B., Rao, D. C. & Morrison, A. C., Aug 1 2019, In: Human molecular genetics. 28, 15, p. 2615-2633 19 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      27 Scopus citations

    • An exome-wide sequencing study of the GOLDN cohort reveals novel associations of coding variants and fasting plasma lipids

      Geng, X., Irvin, M. R., Hidalgo, B., Aslibekyan, S., Srinivasasainagendra, V., An, P., Frazier-Wood, A. C., Tiwari, H. K., Dave, T., Ryan, K., Ordovas, J. M., Straka, R. J., Feitosa, M. F., Hopkins, P. N., Borecki, I., Province, M. A., Mitchell, B. D., Arnett, D. K. & Zhi, D., 2019, In: Frontiers in Genetics. 10, feburay, 158.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      2 Scopus citations

    • Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits

      Kraja, A. T., Liu, C., Fetterman, J. L., Graff, M., Have, C. T., Gu, C., Yanek, L. R., Feitosa, M. F., Arking, D. E., Chasman, D. I., Young, K., Ligthart, S., Hill, W. D., Weiss, S., Luan, J., Giulianini, F., Li-Gao, R., Hartwig, F. P., Lin, S. J. & Wang, L. & 132 others, Richardson, T. G., Yao, J., Fernandez, E. P., Ghanbari, M., Wojczynski, M. K., Lee, W. J., Argos, M., Armasu, S. M., Barve, R. A., Ryan, K. A., An, P., Baranski, T. J., Bielinski, S. J., Bowden, D. W., Broeckel, U., Christensen, K., Chu, A. Y., Corley, J., Cox, S. R., Uitterlinden, A. G., Rivadeneira, F., Cropp, C. D., Daw, E. W., van Heemst, D., de las Fuentes, L., Gao, H., Tzoulaki, I., Ahluwalia, T. S., de Mutsert, R., Emery, L. S., Erzurumluoglu, A. M., Perry, J. A., Fu, M., Forouhi, N. G., Gu, Z., Hai, Y., Harris, S. E., Hemani, G., Hunt, S. C., Irvin, M. R., Jonsson, A. E., Justice, A. E., Kerrison, N. D., Larson, N. B., Lin, K. H., Love-Gregory, L. D., Mathias, R. A., Lee, J. H., Nauck, M., Noordam, R., Ong, K. K., Pankow, J., Patki, A., Pattie, A., Petersmann, A., Qi, Q., Ribel-Madsen, R., Rohde, R., Sandow, K., Schnurr, T. M., Sofer, T., Starr, J. M., Taylor, A. M., Teumer, A., Timpson, N. J., de Haan, H. G., Wang, Y., Weeke, P. E., Williams, C., Wu, H., Yang, W., Zeng, D., Witte, D. R., Weir, B. S., Wareham, N. J., Vestergaard, H., Turner, S. T., Torp-Pedersen, C., Stergiakouli, E., Sheu, W. H. H., Rosendaal, F. R., Ikram, M. A., Franco, O. H., Ridker, P. M., Perls, T. T., Pedersen, O., Nohr, E. A., Newman, A. B., Linneberg, A., Langenberg, C., Kilpeläinen, T. O., Kardia, S. L. R., Jørgensen, M. E., Jørgensen, T., Sørensen, T. I. A., Homuth, G., Hansen, T., Goodarzi, M. O., Deary, I. J., Christensen, C., Chen, Y. D. I., Chakravarti, A., Brandslund, I., Bonnelykke, K., Taylor, K. D., Wilson, J. G., Rodriguez, S., Davies, G., Horta, B. L., Thyagarajan, B., Rao, D. C., Grarup, N., Davila-Roman, V. G., Hudson, G., Guo, X., Arnett, D. K., Hayward, C., Vaidya, D., Mook-Kanamori, D. O., Tiwari, H. K., Levy, D., Loos, R. J. F., Dehghan, A., Elliott, P., Malik, A. N., Scott, R. A., Becker, D. M., de Andrade, M., Province, M. A., Meigs, J. B., Rotter, J. I. & North, K. E., Jan 3 2019, In: American journal of human genetics. 104, 1, p. 112-138 27 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      84 Scopus citations

    • Dairy intake and body composition and cardiometabolic traits among adults: Mendelian randomization analysis of 182041 individuals from 18 studies

      Huang, T., Sun, D., Heianza, Y., Bergholdt, H. K. M., Gao, M., Fang, Z., Ding, M., Frazier-Wood, A. C., North, K. E., Marouli, E., Graff, M., Smith, C. E., Varbo, A., Lemaitre, R. N., Corella, D., Wang, C. A., Tjønneland, A., Overvad, K., Sørensen, T. I. A. & Feitosa, M. F. & 36 others, Wojczynski, M. K., Kähönen, M., Mikkilä, V., Bartz, T. M., Psaty, B. M., Siscovick, D. S., Danning, R. D., Dedoussis, G., Pedersen, O., Hansen, T., Havulinna, A. S., Männistö, S., Rotter, J. I., Sares-Jäske, L., Allison, M. A., Rich, S. S., Sorlí, J. V., Coltell, O., Pennell, C. E., Eastwood, P., Ridker, P. M., Viikari, J., Raitakari, O., Lehtimäki, T., Helminen, M., Wang, Y., Deloukas, P., Knekt, P., Kanerva, N., Kilpeläinen, T. O., Province, M. A., Mozaffarian, D., Chasman, D. I., Nordestgaard, B. G., Ellervik, C. & Qi, L., Jun 2019, In: Clinical chemistry. 65, 6, p. 751-760 10 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      23 Scopus citations

    • Erratum: Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology (The American Journal of Human Genetics (2019) 105(1) (15–28), (S0002929719301880), (10.1016/j.ajhg.2019.05.002))

      Spracklen, C. N., Karaderi, T., Yaghootkar, H., Schurmann, C., Fine, R. S., Kutalik, Z., Preuss, M. H., Lu, Y., Wittemans, L. B. L., Adair, L. S., Allison, M., Amin, N., Auer, P. L., Bartz, T. M., Blüher, M., Boehnke, M., Borja, J. B., Bork-Jensen, J., Broer, L. & Chasman, D. I. & 84 others, Chen, Y. D. I., Chirstofidou, P., Demirkan, A., van Duijn, C. M., Feitosa, M. F., Garcia, M. E., Graff, M., Grallert, H., Grarup, N., Guo, X., Haesser, J., Hansen, T., Harris, T. B., Highland, H. M., Hong, J., Ikram, M. A., Ingelsson, E., Jackson, R., Jousilahti, P., Kähönen, M., Kizer, J. R., Kovacs, P., Kriebel, J., Laakso, M., Lange, L. A., Lehtimäki, T., Li, J., Li-Gao, R., Lind, L., Luan, J., Lyytikäinen, L. P., MacGregor, S., Mackey, D. A., Mahajan, A., Mangino, M., Männistö, S., McCarthy, M. I., McKnight, B., Medina-Gomez, C., Meigs, J. B., Molnos, S., Mook-Kanamori, D., Morris, A. P., de Mutsert, R., Nalls, M. A., Nedeljkovic, I., North, K. E., Pennell, C. E., Pradhan, A. D., Province, M. A., Raitakari, O. T., Raulerson, C. K., Reiner, A. P., Ridker, P. M., Ripatti, S., Roberston, N., Rotter, J. I., Salomaa, V., Sandoval-Zárate, A. A., Sitlani, C. M., Spector, T. D., Strauch, K., Stumvoll, M., Taylor, K. D., Thuesen, B., Tönjes, A., Uitterlinden, A. G., Venturini, C., Walker, M., Wang, C. A., Wang, S., Wareham, N. J., Willems, S. M., Willems van Dijk, K., Wilson, J. G., Wu, Y., Yao, J., Young, K. L., Langenberg, C., Frayling, T. M., Kilpeläinen, T. O., Lindgren, C. M., Loos, R. J. F. & Mohlke, K. L., Sep 5 2019, In: American journal of human genetics. 105, 3, p. 670-671 2 p.

      Research output: Contribution to journal › Comment/debate

      Open Access
      3 Scopus citations

    • Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology

      Spracklen, C. N., Karaderi, T., Yaghootkar, H., Schurmann, C., Fine, R. S., Kutalik, Z., Preuss, M. H., Lu, Y., Wittemans, L. B. L., Adair, L. S., Allison, M., Amin, N., Auer, P. L., Bartz, T. M., Blüher, M., Boehnke, M., Borja, J. B., Bork-Jensen, J., Broer, L. & Chasman, D. I. & 84 others, Chen, Y. D. I., Chirstofidou, P., Demirkan, A., van Duijn, C. M., Feitosa, M. F., Garcia, M. E., Graff, M., Grallert, H., Grarup, N., Guo, X., Haesser, J., Hansen, T., Harris, T. B., Highland, H. M., Hong, J., Ikram, M. A., Ingelsson, E., Jackson, R., Jousilahti, P., Kähönen, M., Kizer, J. R., Kovacs, P., Kriebel, J., Laakso, M., Lange, L. A., Lehtimäki, T., Li, J., Li-Gao, R., Lind, L., Luan, J., Lyytikäinen, L. P., MacGregor, S., Mackey, D. A., Mahajan, A., Mangino, M., Männistö, S., McCarthy, M. I., McKnight, B., Medina-Gomez, C., Meigs, J. B., Molnos, S., Mook-Kanamori, D., Morris, A. P., de Mutsert, R., Nalls, M. A., Nedeljkovic, I., North, K. E., Pennell, C. E., Pradhan, A. D., Province, M. A., Raitakari, O. T., Raulerson, C. K., Reiner, A. P., Ridker, P. M., Ripatti, S., Roberston, N., Rotter, J. I., Salomaa, V., Sandoval-Zárate, A. A., Sitlani, C. M., Spector, T. D., Strauch, K., Stumvoll, M., Taylor, K. D., Thuesen, B., Tönjes, A., Uitterlinden, A. G., Venturini, C., Walker, M., Wang, C. A., Wang, S., Wareham, N. J., Willems, S. M., Willems van Dijk, K., Wilson, J. G., Wu, Y., Yao, J., Young, K. L., Langenberg, C., Frayling, T. M., Kilpeläinen, T. O., Lindgren, C. M., Loos, R. J. F. & Mohlke, K. L., Jul 3 2019, In: American journal of human genetics. 105, 1, p. 15-28 14 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      19 Scopus citations

    • Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

      23and Me Research Team, eQTLgen Consortium, International Cannabis Consortium & Social Science Genetic Association Consortium, Feb 1 2019, In: Nature Genetics. 51, 2, p. 245-257 13 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      424 Scopus citations

    • Genome-wide linkage analysis of carotid artery traits in exceptionally long-lived families

      for the Long Life Family Study, Dec 2019, In: Atherosclerosis. 291, p. 19-26 8 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      5 Scopus citations

    • Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium

      Merino, J., Dashti, H. S., Li, S. X., Sarnowski, C., Justice, A. E., Graff, M., Papoutsakis, C., Smith, C. E., Dedoussis, G. V., Lemaitre, R. N., Wojczynski, M. K., Männistö, S., Ngwa, J. S., Kho, M., Ahluwalia, T. S., Pervjakova, N., Houston, D. K., Bouchard, C., Huang, T. & Orho-Melander, M. & 86 others, Frazier-Wood, A. C., Mook-Kanamori, D. O., Pérusse, L., Pennell, C. E., de Vries, P. S., Voortman, T., Li, O., Kanoni, S., Rose, L. M., Lehtimäki, T., Zhao, J. H., Feitosa, M. F., Luan, J., McKeown, N. M., Smith, J. A., Hansen, T., Eklund, N., Nalls, M. A., Rankinen, T., Huang, J., Hernandez, D. G., Schulz, C. A., Manichaikul, A., Li-Gao, R., Vohl, M. C., Wang, C. A., van Rooij, F. J. A., Shin, J., Kalafati, I. P., Day, F., Ridker, P. M., Kähönen, M., Siscovick, D. S., Langenberg, C., Zhao, W., Astrup, A., Knekt, P., Garcia, M., Rao, D. C., Qi, Q., Ferrucci, L., Ericson, U., Blangero, J., Hofman, A., Pausova, Z., Mikkilä, V., Wareham, N. J., Kardia, S. L. R., Pedersen, O., Jula, A., Curran, J. E., Zillikens, M. C., Viikari, J. S., Forouhi, N. G., Ordovás, J. M., Lieske, J. C., Rissanen, H., Uitterlinden, A. G., Raitakari, O. T., Kiefte-de Jong, J. C., Dupuis, J., Rotter, J. I., North, K. E., Scott, R. A., Province, M. A., Perola, M., Cupples, L. A., Turner, S. T., Sørensen, T. I. A., Salomaa, V., Liu, Y., Sung, Y. J., Qi, L., Bandinelli, S., Rich, S. S., de Mutsert, R., Tremblay, A., Oddy, W. H., Franco, O. H., Paus, T., Florez, J. C., Deloukas, P., Lyytikäinen, L. P., Chasman, D. I., Chu, A. Y. & Tanaka, T., Dec 1 2019, In: Molecular Psychiatry. 24, 12, p. 1920-1932 13 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      46 Scopus citations

    • Insulin Resistance Exacerbates Genetic Predisposition to Nonalcoholic Fatty Liver Disease in Individuals Without Diabetes

      Barata, L., Feitosa, M. F., Bielak, L. F., Halligan, B., Baldridge, A. S., Guo, X., Yerges-Armstrong, L. M., Smith, A. V., Yao, J., Palmer, N. D., VanWagner, L. B., Carr, J. J., Chen, Y. D. I., Allison, M., Budoff, M. J., Handelman, S. K., Kardia, S. L. R., Mosley, T. H., Ryan, K. & Harris, T. B. & 10 others, Launer, L. J., Gudnason, V., Rotter, J. I., Fornage, M., Rasmussen-Torvik, L. J., Borecki, I. B., O’Connell, J. R., Peyser, P. A., Speliotes, E. K. & Province, M. A., Jul 2019, In: Hepatology Communications. 3, 7, p. 894-907 14 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      45 Scopus citations

    • Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions

      De Vries, P. S., Brown, M. R., Bentley, A. R., Sung, Y. J., Winkler, T. W., Ntalla, I., Schwander, K., Kraja, A. T., Guo, X., Franceschini, N., Cheng, C. Y., Sim, X., Vojinovic, D., Huffman, J. E., Musani, S. K., Li, C., Feitosa, M. F., Richard, M. A., Noordam, R. & Aschard, H. & 246 others, Bartz, T. M., Bielak, L. F., Deng, X., Dorajoo, R., Lohman, K. K., Manning, A. K., Rankinen, T., Smith, A. V., Tajuddin, S. M., Evangelou, E., Graff, M., Alver, M., Boissel, M., Chai, J. F., Chen, X., Divers, J., Gandin, I., Gao, C., Goel, A., Hagemeijer, Y., Harris, S. E., Hartwig, F. P., He, M., Horimoto, A. R. V. R., Hsu, F. C., Jackson, A. U., Kasturiratne, A., Komulainen, P., Kühnel, B., Laguzzi, F., Lee, J. H., Luan, J., Lyytikäinen, L. P., Matoba, N., Nolte, I. M., Pietzner, M., Riaz, M., Said, M. A., Scott, R. A., Sofer, T., Stančáková, A., Takeuchi, F., Tayo, B. O., Van Der Most, P. J., Varga, T. V., Wang, Y., Ware, E. B., Wen, W., Yanek, L. R., Zhang, W., Zhao, J. H., Afaq, S., Amin, N., Amini, M., Arking, D. E., Aung, T., Ballantyne, C., Boerwinkle, E., Broeckel, U., Campbell, A., Canouil, M., Charumathi, S., Chen, Y. D. I., Connell, J. M., De Faire, U., De Las Fuentes, L., De Mutsert, R., De Silva, H. J., Ding, J., Dominiczak, A. F., Duan, Q., Eaton, C. B., Eppinga, R. N., Faul, J. D., Fisher, V., Forrester, T., Franco, O. H., Friedlander, Y., Ghanbari, M., Giulianini, F., Grabe, H. J., Grove, M. L., Gu, C. C., Harris, T. B., Heikkinen, S., Heng, C. K., Hirata, M., Hixson, J. E., Howard, B. V., Ikram, M. A., Jacobs, D. R., Johnson, C., Jonas, J. B., Kammerer, C. M., Katsuya, T., Khor, C. C., Kilpeläinen, T. O., Koh, W. P., Koistinen, H. A., Kolcic, I., Kooperberg, C., Krieger, J. E., Kritchevsky, S. B., Kubo, M., Kuusisto, J., Lakka, T. A., Langefeld, C. D., Langenberg, C., Launer, L. J., Lehne, B., Lemaitre, R. N., Li, Y., Liang, J., Liu, J., Liu, K., Loh, M., Louie, T., Mägi, R., Manichaikul, A. W., McKenzie, C. A., Meitinger, T., Metspalu, A., Milaneschi, Y., Milani, L., Mohlke, K. L., Mosley, T. H., Mukamal, K. J., Nalls, M. A., Nauck, M., Nelson, C. P., Sotoodehnia, N., O'Connell, J. R., Palmer, N. D., Pazoki, R., Pedersen, N. L., Peters, A., Peyser, P. A., Polasek, O., Poulter, N., Raffel, L. J., Raitakari, O. T., Reiner, A. P., Rice, T. K., Rich, S. S., Robino, A., Robinson, J. G., Rose, L. M., Rudan, I., Schmidt, C. O., Schreiner, P. J., Scott, W. R., Sever, P., Shi, Y., Sidney, S., Sims, M., Smith, B. H., Smith, J. A., Snieder, H., Starr, J. M., Strauch, K., Tan, N., Taylor, K. D., Teo, Y. Y., Tham, Y. C., Uitterlinden, A. G., Van Heemst, D., Vuckovic, D., Waldenberger, M., Wang, L., Wang, Y., Wang, Z., Wei, W. B., Williams, C., Wilson, G., Wojczynski, M. K., Yao, J., Yu, B., Yu, C., Yuan, J. M., Zhao, W., Zonderman, A. B., Becker, D. M., Boehnke, M., Bowden, D. W., Chambers, J. C., Deary, I. J., Esko, T., Farrall, M., Franks, P. W., Freedman, B. I., Froguel, P., Gasparini, P., Gieger, C., Horta, B. L., Kamatani, Y., Kato, N., Kooner, J. S., Laakso, M., Leander, K., Lehtimäki, T., Magnusson, P. K. E., Penninx, B., Pereira, A. C., Rauramaa, R., Samani, N. J., Scott, J., Shu, X. O., Van Der Harst, P., Wagenknecht, L. E., Wang, Y. X., Wareham, N. J., Watkins, H., Weir, D. R., Wickremasinghe, A. R., Zheng, W., Elliott, P., North, K. E., Bouchard, C., Evans, M. K., Gudnason, V., Liu, C. T., Liu, Y., Psaty, B. M., Ridker, P. M., Van Dam, R. M., Kardia, S. L. R., Zhu, X., Rotimi, C. N., Mook-Kanamori, D. O., Fornage, M., Kelly, T. N., Fox, E. R., Hayward, C., Van Duijn, C. M., Tai, E. S., Wong, T. Y., Liu, J., Rotter, J. I., Gauderman, W. J., Province, M. A., Munroe, P. B., Rice, K., Chasman, D. I., Cupples, L. A., Rao, D. C. & Morrison, A. C., Jun 1 2019, In: American journal of epidemiology. 188, 6, p. 1033-1054 22 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      72 Scopus citations

    • Multi-ancestry genome-wide gene–smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

      Understanding Society Scientific group, Lifelines Cohort, COGENT-Kidney Consortium & EPIC-InterAct Consortium, Apr 1 2019, In: Nature Genetics. 51, 4, p. 636-648 13 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      83 Scopus citations

    • Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration

      Noordam, R., Bos, M. M., Wang, H., Winkler, T. W., Bentley, A. R., Kilpeläinen, T. O., de Vries, P. S., Sung, Y. J., Schwander, K., Cade, B. E., Manning, A., Aschard, H., Brown, M. R., Chen, H., Franceschini, N., Musani, S. K., Richard, M., Vojinovic, D., Aslibekyan, S. & Bartz, T. M. & 128 others, de las Fuentes, L., Feitosa, M., Horimoto, A. R., Ilkov, M., Kho, M., Kraja, A., Li, C., Lim, E., Liu, Y., Mook-Kanamori, D. O., Rankinen, T., Tajuddin, S. M., van der Spek, A., Wang, Z., Marten, J., Laville, V., Alver, M., Evangelou, E., Graff, M. E., He, M., Kühnel, B., Lyytikäinen, L. P., Marques-Vidal, P., Nolte, I. M., Palmer, N. D., Rauramaa, R., Shu, X. O., Snieder, H., Weiss, S., Wen, W., Yanek, L. R., Adolfo, C., Ballantyne, C., Bielak, L., Biermasz, N. R., Boerwinkle, E., Dimou, N., Eiriksdottir, G., Gao, C., Gharib, S. A., Gottlieb, D. J., Haba-Rubio, J., Harris, T. B., Heikkinen, S., Heinzer, R., Hixson, J. E., Homuth, G., Ikram, M. A., Komulainen, P., Krieger, J. E., Lee, J., Liu, J., Lohman, K. K., Luik, A. I., Mägi, R., Martin, L. W., Meitinger, T., Metspalu, A., Milaneschi, Y., Nalls, M. A., O’Connell, J., Peters, A., Peyser, P., Raitakari, O. T., Reiner, A. P., Rensen, P. C. N., Rice, T. K., Rich, S. S., Roenneberg, T., Rotter, J. I., Schreiner, P. J., Shikany, J., Sidney, S. S., Sims, M., Sitlani, C. M., Sofer, T., Strauch, K., Swertz, M. A., Taylor, K. D., Uitterlinden, A. G., van Duijn, C. M., Völzke, H., Waldenberger, M., Wallance, R. B., van Dijk, K. W., Yu, C., Zonderman, A. B., Becker, D. M., Elliott, P., Esko, T., Gieger, C., Grabe, H. J., Lakka, T. A., Lehtimäki, T., North, K. E., Penninx, B. W. J. H., Vollenweider, P., Wagenknecht, L. E., Wu, T., Xiang, Y. B., Zheng, W., Arnett, D. K., Bouchard, C., Evans, M. K., Gudnason, V., Kardia, S., Kelly, T. N., Kritchevsky, S. B., Loos, R. J. F., Pereira, A. C., Province, M., Psaty, B. M., Rotimi, C., Zhu, X., Amin, N., Cupples, L. A., Fornage, M., Fox, E. F., Guo, X., Gauderman, W. J., Rice, K., Kooperberg, C., Munroe, P. B., Liu, C. T., Morrison, A. C., Rao, D. C., van Heemst, D. & Redline, S., Dec 1 2019, In: Nature communications. 10, 1, 5121.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      51 Scopus citations

    • Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity

      Lifelines Cohort Study, Dec 1 2019, In: Nature communications. 10, 1, 376.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      62 Scopus citations
    • 2018

      A high throughput, functional screen of human Body Mass Index GWAS loci using tissue-specific RNAi Drosophila melanogaster crosses

      Baranski, T. J., Kraja, A. T., Fink, J. L., Feitosa, M., Lenzini, P. A., Borecki, I. B., Liu, C. T., Cupples, L. A., North, K. E. & Province, M. A., Apr 2018, In: PLoS genetics. 14, 4, e1007222.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      22 Scopus citations

    • A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

      The CHARGE Neurology Working Group, The COGENT-Kidney Consortium, The GIANT Consortium & Lifelines Cohort Study, Mar 1 2018, In: American journal of human genetics. 102, 3, p. 375-400 26 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      106 Scopus citations

    • An exome-wide sequencing study of lipid response to high-fat meal and fenofibrate in Caucasians from the GOLDN cohort

      Geng, X., Irvin, M. R., Hidalgo, B., Aslibekyan, S., Srinivasasainagendra, V., An, P., Frazier-Wood, A. C., Tiwari, H. K., Dave, T., Ryan, K., Ordovas, J. M., Straka, R. J., Feitosa, M. F., Hopkins, P. N., Borecki, I., Province, M. A., Mitchell, B. D., Arnett, D. K. & Zhi, D., 2018, In: Journal of lipid research. 59, 4, p. 722-729 8 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      7 Scopus citations

    • Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and Tamoxifen Therapy

      Goetz, M. P., Sangkuhl, K., Guchelaar, H. J., Schwab, M., Province, M., Whirl-Carrillo, M., Symmans, W. F., McLeod, H. L., Ratain, M. J., Zembutsu, H., Gaedigk, A., van Schaik, R. H., Ingle, J. N., Caudle, K. E. & Klein, T. E., May 2018, In: Clinical pharmacology and therapeutics. 103, 5, p. 770-777 8 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      258 Scopus citations

    • Data for GAW20: Genome-wide DNA sequence variation and epigenome-wide DNA methylation before and after fenofibrate treatment in a family study of metabolic phenotypes 06 Biological Sciences 0604 Genetics

      Aslibekyan, S., Almasy, L., Province, M. A., Absher, D. M. & Arnett, D. K., Sep 17 2018, In: BMC Proceedings. 12, 35.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      10 Scopus citations

    • Epigenomics and metabolomics reveal the mechanism of the APOA2 -saturated fat intake interaction affecting obesity

      Lai, C. Q., Smith, C. E., Parnell, L. D., Lee, Y. C., Corella, D., Hopkins, P., Hidalgo, B. A., Aslibekyan, S., Province, M. A., Absher, D., Arnett, D. K., Tucker, K. L. & Ordovas, J. M., Jul 1 2018, In: American Journal of Clinical Nutrition. 108, 1, p. 188-200 13 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      51 Scopus citations

    • Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

      23andMe Research Team, COGENT (Cognitive Genomics Consortium) & Social Science Genetic Association Consortium, Aug 1 2018, In: Nature Genetics. 50, 8, p. 1112-1121 10 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      1512 Scopus citations

    • Genetics of human longevity from incomplete data: New findings from the long life family study

      Yashin, A. I., Arbeev, K. G., Wu, D., Arbeeva, L. S., Bagley, O., Stallard, E., Kulminski, A. M., Akushevich, I., Fang, F., Wojczynski, M. K., Christensen, K., Newman, A. B., Boudreau, R. M., Province, M. A., Thielke, S., Perls, T. T., An, P., Elo, I. & Ukraintseva, S. V., Oct 8 2018, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 73, 11, p. 1472-1481 10 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      23 Scopus citations

    • Genome-Wide Interactions with Dairy Intake for Body Mass Index in Adults of European Descent

      Smith, C. E., Follis, J. L., Dashti, H. S., Tanaka, T., Graff, M., Fretts, A. M., Kilpeläinen, T. O., Wojczynski, M. K., Richardson, K., Nalls, M. A., Schulz, C. A., Liu, Y., Frazier-Wood, A. C., van Eekelen, E., Wang, C., de Vries, P. S., Mikkilä, V., Rohde, R., Psaty, B. M. & Hansen, T. & 43 others, Feitosa, M. F., Lai, C. Q., Houston, D. K., Ferruci, L., Ericson, U., Wang, Z., de Mutsert, R., Oddy, W. H., de Jonge, E. A. L., Seppälä, I., Justice, A. E., Lemaitre, R. N., Sørensen, T. I. A., Province, M. A., Parnell, L. D., Garcia, M. E., Bandinelli, S., Orho-Melander, M., Rich, S. S., Rosendaal, F. R., Pennell, C. E., Kiefte-de Jong, J. C., Kähönen, M., Young, K. L., Pedersen, O., Aslibekyan, S., Rotter, J. I., Mook-Kanamori, D. O., Zillikens, M. C., Raitakari, O. T., North, K. E., Overvad, K., Arnett, D. K., Hofman, A., Lehtimäki, T., Tjønneland, A., Uitterlinden, A. G., Rivadeneira, F., Franco, O. H., German, J. B., Siscovick, D. S., Cupples, L. A. & Ordovás, J. M., Feb 1 2018, In: Molecular Nutrition and Food Research. 62, 3, 1700347.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      9 Scopus citations

    • How Well Does the Family Longevity Selection Score Work: A Validation Test Using the Utah Population Database

      Arbeeva, L. S., Hanson, H. A., Arbeev, K. G., Kulminski, A. M., Stallard, E., Ukraintseva, S. V., Wu, D., Boudreau, R. M., Province, M. A., Smith, K. R. & Yashin, A. I., Oct 1 2018, In: Frontiers in Public Health. 6, 277.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      8 Scopus citations

    • Meta-analysis of exome array data identifies six novel genetic loci for lung function

      Tobin, M. D., London, S. J., Jackson, V. E., Latourelle, J. C., Wain, L. V., Smith, A. V., Grove, M. L., Bartz, T. M., Obeidat, M., Province, M. A., Gao, W., Qaiser, B., Porteous, D. J., Cassano, P. A., Ahluwalia, T. S., Grarup, N., Li, J., Altmaier, E., Marten, J. & Harris, S. E. & 87 others, Manichaikul, A., Pottinger, T. D., Li-Gao, R., Lind-Thomsen, A., Mahajan, A., Lahousse, L., Imboden, M., Teumer, A., Prins, B., Lyytikäinen, L. P., Eiriksdottir, G., Franceschini, N., Sitlani, C. M., Brody, J. A., Bossé, Y., Timens, W., Kraja, A., Loukola, A., Tang, W., Liu, Y., Bork-Jensen, J., Justesen, J. M., Linneberg, A., Lange, L. A., Rawal, R., Karrasch, S., Huffman, J. E., Smith, B. H., Davies, G., Burkart, K. M., Mychaleckyj, J. C., Bonten, T. N., Enroth, S., Lind, L., Brusselle, G. G., Kumar, A., Stubbe, B., Kähönen, M., Wyss, A. B., Psaty, B. M., Heckbert, S. R., Hao, K., Rantanen, T., Kritchevsky, S. B., Lohman, K., Skaaby, T., Pisinger, C., Hansen, T., Schulz, H., Polasek, O., Campbell, A. I., Starr, J. M., Rich, S. S., Mook-Kanamori, D. O., Johansson, Å., Ingelsson, E., Uitterlinden, A. G., Weiss, S., Raitakari, O. T., Gudnason, V., North, K. E., Gharib, S. A., Sin, D. D., Taylor, K. D., O'Connor, G. T., Kaprio, J., Harris, T. B., Pederson, O., Vestergaard, H., Wilson, J. G., Strauch, K., Hayward, C., Kerr, S. M., Deary, I. J., Barr, R. G., de Mutsert, R., Gyllensten, U., Morris, A. P., Ikram, M. A., Probst-Hensch, N., Gläser, S., Zeggini, E., Lehtimäki, T., Strachan, D. P., Dupuis, J., Morrison, A. C. & Hall, I. P., 2018, In: Wellcome Open Research. 3, 4.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      3 Scopus citations

    • Meta-analysis of exome array data identifies six novel genetic loci for lung function.

      Understanding Society Scientific group, 2018, In: Wellcome Open Research. 3, 4.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      20 Scopus citations

    • Methods for detecting methylation by SNP interaction in GAW20 simulation

      Warwick Daw, E., Hicks, J., Lenzini, P., Lin, S. J., Wang, J., Williams, C., An, P., Province, M. A. & Kraja, A. T., Sep 17 2018, In: BMC Proceedings. 12, 37.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      2 Scopus citations

    • Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function

      Wyss, A. B., Sofer, T., Lee, M. K., Terzikhan, N., Nguyen, J. N., Lahousse, L., Latourelle, J. C., Smith, A. V., Bartz, T. M., Feitosa, M. F., Gao, W., Ahluwalia, T. S., Tang, W., Oldmeadow, C., Duan, Q., de Jong, K., Wojczynski, M. K., Wang, X. Q., Noordam, R. & Hartwig, F. P. & 82 others, Jackson, V. E., Wang, T., Obeidat, M., Hobbs, B. D., Huan, T., Gui, H., Parker, M. M., Hu, D., Mogil, L. S., Kichaev, G., Jin, J., Graff, M., Harris, T. B., Kalhan, R., Heckbert, S. R., Paternoster, L., Burkart, K. M., Liu, Y., Holliday, E. G., Wilson, J. G., Vonk, J. M., Sanders, J. L., Barr, R. G., de Mutsert, R., Menezes, A. M. B., Adams, H. H. H., van den Berge, M., Joehanes, R., Levin, A. M., Liberto, J., Launer, L. J., Morrison, A. C., Sitlani, C. M., Celedón, J. C., Kritchevsky, S. B., Scott, R. J., Christensen, K., Rotter, J. I., Bonten, T. N., Wehrmeister, F. C., Bossé, Y., Xiao, S., Oh, S., Franceschini, N., Brody, J. A., Kaplan, R. C., Lohman, K., McEvoy, M., Province, M. A., Rosendaal, F. R., Taylor, K. D., Nickle, D. C., Williams, L. K., Burchard, E. G., Wheeler, H. E., Sin, D. D., Gudnason, V., North, K. E., Fornage, M., Psaty, B. M., Myers, R. H., O’Connor, G., Hansen, T., Laurie, C. C., Cassano, P. A., Sung, J., Kim, W. J., Attia, J. R., Lange, L., Boezen, H. M., Thyagarajan, B., Rich, S. S., Mook-Kanamori, D. O., Horta, B. L., Uitterlinden, A. G., Im, H. K., Cho, M. H., Brusselle, G. G., Gharib, S. A., Dupuis, J., Manichaikul, A. & London, S. J., Dec 1 2018, In: Nature communications. 9, 1, 2976.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      75 Scopus citations

    • Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries

      Feitosa, M. F., Kraja, A. T., Chasman, D. I., Sung, Y. J., Winkler, T. W., Ntalla, I., Guo, X., Franceschini, N., Cheng, C. Y., Sim, X., Vojinovic, D., Marten, J., Musani, S. K., Li, C., Bentley, A. R., Brown, M. R., Schwander, K., Richard, M. A., Noordam, R. & Aschard, H. & 252 others, Bartz, T. M., Bielak, L. F., Dorajoo, R., Fisher, V., Hartwig, F. P., Horimoto, A. R. V. R., Lohman, K. K., Manning, A. K., Rankinen, T., Smith, A. V., Tajuddin, S. M., Wojczynski, M. K., Alver, M., Boissel, M., Cai, Q., Campbell, A., Chai, J. F., Chen, X., Divers, J., Gao, C., Goel, A., Hagemeijer, Y., Harris, S. E., He, M., Hsu, F. C., Jackson, A. U., Kähönen, M., Kasturiratne, A., Komulainen, P., Kühnel, B., Laguzzi, F., Luan, J., Matoba, N., Nolte, I. M., Padmanabhan, S., Riaz, M., Rueedi, R., Robino, A., Said, M. A., Scott, R. A., Sofer, T., Stančáková, A., Takeuchi, F., Tayo, B. O., Van Der Most, P. J., Varga, T. V., Vitart, V., Wang, Y., Ware, E. B., Warren, H. R., Weiss, S., Wen, W., Yanek, L. R., Zhang, W., Zhao, J. H., Afaq, S., Amin, N., Amini, M., Arking, D. E., Aung, T., Boerwinkle, E., Borecki, I., Broeckel, U., Brown, M., Brumat, M., Burke, G. L., Canouil, M., Chakravarti, A., Charumathi, S., Chen, Y. D. I., Connell, J. M., Correa, A., De Las Fuentes, L., De Mutsert, R., De Silva, H. J., Deng, X., Ding, J., Duan, Q., Eaton, C. B., Ehret, G., Eppinga, R. N., Evangelou, E., Faul, J. D., Felix, S. B., Forouhi, N. G., Forrester, T., Franco, O. H., Friedlander, Y., Gandin, I., Gao, H., Ghanbari, M., Gigante, B., Gu, C. C., Gu, D., Hagenaars, S. P., Hallmans, G., Harris, T. B., He, J., Heikkinen, S., Heng, C. K., Hirata, M., Howard, B. V., Ikram, M. A., John, U., Katsuya, T., Khor, C. C., Kilpeläinen, T. O., Koh, W. P., Krieger, J. E., Kritchevsky, S. B., Kubo, M., Kuusisto, J., Lakka, T. A., Langefeld, C. D., Langenberg, C., Launer, L. J., Lehne, B., Lewis, C. E., Li, Y., Lin, S., Liu, J., Liu, J., Loh, M., Louie, T., Mägi, R., McKenzie, C. A., Meitinger, T., Metspalu, A., Milaneschi, Y., Milani, L., Mohlke, K. L., Momozawa, Y., Nalls, M. A., Nelson, C. P., Sotoodehnia, N., Norris, J. M., O'Connell, J. R., Palmer, N. D., Perls, T., Pedersen, N. L., Peters, A., Peyser, P. A., Poulter, N., Raffel, L. J., Raitakari, O. T., Roll, K., Rose, L. M., Rosendaal, F. R., Rotter, J. I., Schmidt, C. O., Schreiner, P. J., Schupf, N., Scott, W. R., Sever, P. S., Shi, Y., Sidney, S., Sims, M., Sitlani, C. M., Smith, J. A., Snieder, H., Starr, J. M., Strauch, K., Stringham, H. M., Tan, N. Y. Q., Tang, H., Taylor, K. D., Teo, Y. Y., Tham, Y. C., Turner, S. T., Uitterlinden, A. G., Vollenweider, P., Waldenberger, M., Wang, L., Wang, Y. X., Wei, W. B., Williams, C., Yao, J., Yu, C., Yuan, J. M., Zhao, W., Zonderman, A. B., Becker, D. M., Boehnke, M., Bowden, D. W., Chambers, J. C., Deary, I. J., Esko, T., Farrall, M., Franks, P. W., Freedman, B. I., Froguel, P., Gasparini, P., Gieger, C., Jonas, J. B., Kamatani, Y., Kato, N., Kooner, J. S., Kutalik, Z., Laakso, M., Laurie, C. C., Leander, K., Lehtimäki, T., Magnusson, P. K. E., Oldehinkel, A. J., Penninx, B. W. J. H., Polasek, O., Porteous, D. J., Rauramaa, R., Samani, N. J., Scott, J., Shu, X. O., Van Der Harst, P., Wagenknecht, L. E., Wareham, N. J., Watkins, H., Weir, D. R., Wickremasinghe, A. R., Wu, T., Zheng, W., Bouchard, C., Christensen, K., Evans, M. K., Gudnason, V., Horta, B. L., Kardia, S. L. R., Liu, Y., Pereira, A. C., Psaty, B. M., Ridker, P. M., Van Dam, R. M., Gauderman, W. J., Zhu, X., Mook-Kanamori, D. O., Fornage, M., Rotimi, C. N., Cupples, L. A., Kelly, T. N., Fox, E. R., Hayward, C., Van Duijn, C. M., Tai, E. S., Wong, T. Y., Kooperberg, C., Palmas, W., Rice, K., Morrison, A. C., Elliott, P., Caulfield, M. J., Munroe, P. B., Rao, D. C., Province, M. A. & Levy, D., Jun 2018, In: PloS one. 13, 6, e0198166.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      73 Scopus citations

    • Simulation of a medication and methylation effects on triglycerides in the Genetic Analysis Workshop 20 06 Biological Sciences 0604 Genetics

      Kraja, A. T., An, P., Lenzini, P., Lin, S. J., Williams, C., Hicks, J. E., Warwick Daw, E. & Province, M. A., Sep 17 2018, In: BMC Proceedings. 12, 25.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      5 Scopus citations

    • The NIEHS TaRGET II Consortium and environmental epigenomics

      TaRGET II Consortium, Mar 6 2018, In: Nature Biotechnology. 36, 3, p. 225-227 3 p.

      Research output: Contribution to journal › Letter › peer-review

      Open Access
      69 Scopus citations

    • VarExp: Estimating variance explained by genome-wide GxE summary statistics

      Laville, V., Bentley, A. R., Privé, F., Zhu, X., Gauderman, J., Winkler, T. W., Province, M., Rao, D. C. & Aschard, H., Oct 1 2018, In: Bioinformatics. 34, 19, p. 3412-3414 3 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      11 Scopus citations
    • 2017

      A novel TCF7L2 type 2 diabetes SNP identified from fine mapping in African American women

      MEDIA Consortium, Mar 1 2017, In: PloS one. 12, 3, e0172577.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      9 Scopus citations

    • Causal effect of plasminogen activator inhibitor type 1 on coronary heart disease

      CHARGE Consortium Hemostatic Factor Working Group, ICBP Consortium & CHARGE Consortium Subclinical Working Group, Jun 1 2017, In: Journal of the American Heart Association. 6, 6, e004918.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      100 Scopus citations

    • CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits

      Macé, A., Tuke, M. A., Deelen, P., Kristiansson, K., Mattsson, H., Nõukas, M., Sapkota, Y., Schick, U., Porcu, E., Rüeger, S., McDaid, A. F., Porteous, D., Winkler, T. W., Salvi, E., Shrine, N., Liu, X., Ang, W. Q., Zhang, W., Feitosa, M. F. & Venturini, C. & 86 others, Van Der Most, P. J., Rosengren, A., Wood, A. R., Beaumont, R. N., Jones, S. E., Ruth, K. S., Yaghootkar, H., Tyrrell, J., Havulinna, A. S., Boers, H., Mägi, R., Kriebel, J., Müller-Nurasyid, M., Perola, M., Nieminen, M., Lokki, M. L., Kähönen, M., Viikari, J. S., Geller, F., Lahti, J., Palotie, A., Koponen, P., Lundqvist, A., Rissanen, H., Bottinger, E. P., Afaq, S., Wojczynski, M. K., Lenzini, P., Nolte, I. M., Sparsø, T., Schupf, N., Christensen, K., Perls, T. T., Newman, A. B., Werge, T., Snieder, H., Spector, T. D., Chambers, J. C., Koskinen, S., Melbye, M., Raitakari, O. T., Lehtimäki, T., Tobin, M. D., Wain, L. V., Sinisalo, J., Peters, A., Meitinger, T., Martin, N. G., Wray, N. R., Montgomery, G. W., Medland, S. E., Swertz, M. A., Vartiainen, E., Borodulin, K., Männistö, S., Murray, A., Bochud, M., Jacquemont, S., Rivadeneira, F., Hansen, T. F., Oldehinkel, A. J., Mangino, M., Province, M. A., Deloukas, P., Kooner, J. S., Freathy, R. M., Pennell, C., Feenstra, B., Strachan, D. P., Lettre, G., Hirschhorn, J., Cusi, D., Heid, I. M., Hayward, C., Männik, K., Beckmann, J. S., Loos, R. J. F., Nyholt, D. R., Metspalu, A., Eriksson, J. G., Weedon, M. N., Salomaa, V., Franke, L., Reymond, A., Frayling, T. M. & Kutalik, Z., Dec 1 2017, In: Nature communications. 8, 1, 744.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      60 Scopus citations

    • Genome- and CD4+ T-cell methylome-wide association study of circulating trimethylamine-N-oxide in the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN)

      Aslibekyan, S., Irvin, M. R., Hidalgo, B. A., Perry, R. T., Jeyarajah, E. J., Garcia, E., Shalaurova, I., Hopkins, P. N., Province, M. A., Tiwari, H. K., Ordovas, J. M., Absher, D. M. & Arnett, D. K., Jun 1 2017, In: Journal of Nutrition and Intermediary Metabolism. 8, p. 1-7 7 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      13 Scopus citations

    • Loss of Cardioprotective Effects at the ADAMTS7 Locus as a Result of Gene-Smoking Interactions

      Saleheen, D., Zhao, W., Young, R., Nelson, C. P., Ho, W., Ferguson, J. F., Rasheed, A., Ou, K., Nurnberg, S. T., Bauer, R. C., Goel, A., Do, R., Stewart, A. F. R., Hartiala, J., Zhang, W., Thorleifsson, G., Strawbridge, R. J., Sinisalo, J., Kanoni, S. & Sedaghat, S. & 50 others, Marouli, E., Kristiansson, K., Zhao, J. H., Scott, R., Gauguier, D., Shah, S. H., Smith, A. V., Van Zuydam, N., Cox, A. J., Willenborg, C., Kessler, T., Zeng, L., Province, M. A., Ganna, A., Lind, L., Pedersen, N. L., White, C. C., Joensuu, A., Kleber, M. E., Hall, A. S., März, W., Salomaa, V., O'Donnell, C., Ingelsson, E., Feitosa, M. F., Erdmann, J., Bowden, D. W., Palmer, C. N. A., Gudnason, V., Faire, U. D., Zalloua, P., Wareham, N., Thompson, J. R., Kuulasmaa, K., Dedoussis, G., Perola, M., Dehghan, A., Chambers, J. C., Kooner, J., Allayee, H., Deloukas, P., McPherson, R., Stefansson, K., Schunkert, H., Kathiresan, S., Farrall, M., Marcel Frossard, P., Rader, D. J., Samani, N. J. & Reilly, M. P., Jun 13 2017, In: Circulation. 135, 24, p. 2336-2353 18 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      44 Scopus citations

    • New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

      behalf of the CHARGE EXOME BP, CHD Exome+, Exome BP, GoT2D:T2DGenes Consortia, The UK Biobank Cardio-Metabolic Traits Consortium Blood Pressure Working Group & The Understanding Society Scientific Group, Oct 1 2017, In: Circulation: Cardiovascular Genetics. 10, 5, e001778.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      48 Scopus citations

    • Sex Differences in Blood HDL-c, the Total Cholesterol/HDL-c Ratio, and Palmitoleic Acid are Not Associated with Variants in Common Candidate Genes

      Klingel, S. L., Roke, K., Hidalgo, B., Aslibekyan, S., Straka, R. J., An, P., Province, M. A., Hopkins, P. N., Arnett, D. K., Ordovas, J. M., Lai, C. Q. & Mutch, D. M., Dec 1 2017, In: Lipids. 52, 12, p. 969-980 12 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      18 Scopus citations

    • Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms

      the eMERGE Consortium, the DIAGRAM Consortium, the MuTHER Consortium, SIGMA T2D Consortium, the DIAGRAM Consortium, the MuTHER Consortium, SIGMA T2D Consortium, the MuTHER Consortium, SIGMA T2D Consortium, SIGMA T2D Consortium, MEDIA Consortium, the FIND Consortium, the eMERGE Consortium, the DIAGRAM Consortium, the MuTHER Consortium, SIGMA T2D Consortium, the eMERGE Consortium, the DIAGRAM Consortium, the MuTHER Consortium & SIGMA T2D Consortium, Jun 29 2017, In: Cell. 170, 1, p. 199-212.e20

      Research output: Contribution to journal › Article › peer-review

      Open Access
      122 Scopus citations
    • 2016

      A Framework for Interpreting Type I Error Rates from a Product-Term Model of Interaction Applied to Quantitative Traits

      Rao, T. J. & Province, M. A., Feb 1 2016, In: Genetic Epidemiology. 40, 2, p. 144-153 10 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      8 Scopus citations

    • An Empirical Comparison of Joint and Stratified Frameworks for Studying G × E Interactions: Systolic Blood Pressure and Smoking in the CHARGE Gene-Lifestyle Interactions Working Group

      Sung, Y. J., Winkler, T. W., Manning, A. K., Aschard, H., Gudnason, V., Harris, T. B., Smith, A. V., Boerwinkle, E., Brown, M. R., Morrison, A. C., Fornage, M., Lin, L. A., Richard, M., Bartz, T. M., Psaty, B. M., Hayward, C., Polasek, O., Marten, J., Rudan, I. & Feitosa, M. F. & 38 others, Kraja, A. T., Province, M. A., Deng, X., Fisher, V. A., Zhou, Y., Bielak, L. F., Smith, J., Huffman, J. E., Padmanabhan, S., Smith, B. H., Ding, J., Liu, Y., Lohman, K., Bouchard, C., Rankinen, T., Rice, T. K., Arnett, D., Schwander, K., Guo, X., Palmas, W., Rotter, J. I., Alfred, T., Bottinger, E. P., Loos, R. J. F., Amin, N., Franco, O. H., van Duijn, C. M., Vojinovic, D., Chasman, D. I., Ridker, P. M., Rose, L. M., Kardia, S., Zhu, X., Rice, K., Borecki, I. B., Rao, D. C., Gauderman, W. J. & Cupples, L. A., Jul 1 2016, In: Genetic Epidemiology. 40, 5, p. 404-415 12 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      18 Scopus citations

    • Assessment of postprandial triglycerides in clinical practice: Validation in a general population and coronary heart disease patients

      Perez-Martinez, P., Alcala-Diaz, J. F., Kabagambe, E. K., Garcia-Rios, A., Tsai, M. Y., Delgado-Lista, J., Kolovou, G., Straka, R. J., Gomez-Delgado, F., Hopkins, P. N., Marin, C., Borecki, I., Yubero-Serrano, E. M., Hixson, J. E., Camargo, A., Province, M. A., Lopez-Moreno, J., Rodriguez-Cantalejo, F., Tinahones, F. J. & Mikhailidis, D. P. & 4 others, Perez-Jimenez, F., Arnett, D. K., Ordovas, J. M. & Lopez-Miranda, J., Sep 1 2016, In: Journal of Clinical Lipidology. 10, 5, p. 1163-1171 9 p.

      Research output: Contribution to journal › Article › peer-review

      22 Scopus citations