Search results

  • 2024

    Genetic drivers of heterogeneity in type 2 diabetes pathophysiology

    VA Million Veteran Program, Mar 1 2024, In: Nature. 627, 8003, p. 347-357 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    8 Scopus citations
  • Genetic Pleiotropy Between Pulmonary Function and Age-RelatedTraits:The Long Life Family Study

    Feitosa, M. F., Wojczynski, M. K., Anema, J. A., WarwickDaw, E., Wang, L., Santanasto, A. J., Nygaard, M. & Province, M. A., Mar 1 2024, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 79, 3, glac046.

    Research output: Contribution to journalArticlepeer-review

    2 Scopus citations
  • Genetic risk accentuates dietary effects on hepatic steatosis, inflammation and fibrosis in a population-based cohort

    Chen, V. L., Du, X., Oliveri, A., Chen, Y., Kuppa, A., Halligan, B. D., Province, M. A. & Speliotes, E. K., 2024, (Accepted/In press) In: Journal of Hepatology.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • PathFinder: a novel graph transformer model to infer multi-cell intra- and inter-cellular signaling pathways and communications

    Feng, J., Song, H., Province, M., Li, G., Payne, P. R. O., Chen, Y. & Li, F., 2024, In: Frontiers in Cellular Neuroscience. 18, 1369242.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • The Protective Effect of Familial Longevity Persists After Age 100: Findings From the Danish National Registers

    Galvin, A., Pedersen, J. K., Wojczynski, M. K., Ukraintseva, S., Arbeev, K., Feitosa, M., Province, M. A. & Christensen, K., Jan 1 2024, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 79, 1, glad164.

    Research output: Contribution to journalArticlepeer-review

  • 2023

    Correction to: The power of genetic diversity in genome-wide association studies of lipids (Nature, (2021), 600, 7890, (675-679), 10.1038/s41586-021-04064-3)

    Graham, S. E., Clarke, S. L., Wu, K. H. H., Kanoni, S., Zajac, G. J. M., Ramdas, S., Surakka, I., Ntalla, I., Vedantam, S., Winkler, T. W., Locke, A. E., Marouli, E., Hwang, M. Y., Han, S., Narita, A., Choudhury, A., Bentley, A. R., Ekoru, K., Verma, A., Trivedi, B., & 506 othersMartin, H. C., Hunt, K. A., Hui, Q., Klarin, D., Zhu, X., Thorleifsson, G., Helgadottir, A., Gudbjartsson, D. F., Holm, H., Olafsson, I., Akiyama, M., Sakaue, S., Terao, C., Kanai, M., Zhou, W., Brumpton, B. M., Rasheed, H., Ruotsalainen, S. E., Havulinna, A. S., Veturi, Y., Feng, Q. P., Rosenthal, E. A., Lingren, T., Pacheco, J. A., Pendergrass, S. A., Haessler, J., Giulianini, F., Bradford, Y., Miller, J. E., Campbell, A., Lin, K., Millwood, I. Y., Hindy, G., Rasheed, A., Faul, J. D., Zhao, W., Weir, D. R., Turman, C., Huang, H., Graff, M., Mahajan, A., Brown, M. R., Zhang, W., Yu, K., Schmidt, E. M., Pandit, A., Gustafsson, S., Yin, X., Luan, J., Zhao, J. H., Matsuda, F., Jang, H. M., Yoon, K., Medina-Gomez, C., Pitsillides, A., Hottenga, J. J., Willemsen, G., Wood, A. R., Ji, Y., Gao, Z., Haworth, S., Mitchell, R. E., Chai, J. F., Aadahl, M., Yao, J., Manichaikul, A., Warren, H. R., Ramirez, J., Bork-Jensen, J., Kårhus, L. L., Goel, A., Sabater-Lleal, M., Noordam, R., Sidore, C., Fiorillo, E., McDaid, A. F., Marques-Vidal, P., Wielscher, M., Trompet, S., Sattar, N., Møllehave, L. T., Thuesen, B. H., Munz, M., Zeng, L., Huang, J., Yang, B., Poveda, A., Kurbasic, A., Lamina, C., Forer, L., Scholz, M., Galesloot, T. E., Bradfield, J. P., Daw, E. W., Zmuda, J. M., Mitchell, J. S., Fuchsberger, C., Christensen, H., Brody, J. A., Feitosa, M. F., Wojczynski, M. K., Preuss, M., Mangino, M., Christofidou, P., Verweij, N., Benjamins, J. W., Engmann, J., Kember, R. L., Slieker, R. C., Lo, K. S., Zilhao, N. R., Le, P., Kleber, M. E., Delgado, G. E., Huo, S., Ikeda, D. D., Iha, H., Yang, J., Liu, J., Leonard, H. L., Marten, J., Schmidt, B., Arendt, M., Smyth, L. J., Cañadas-Garre, M., Wang, C., Nakatochi, M., Wong, A., Hutri-Kähönen, N., Sim, X., Xia, R., Huerta-Chagoya, A., Fernandez-Lopez, J. C., Lyssenko, V., Ahmed, M., Jackson, A. U., Yousri, N. A., Irvin, M. R., Oldmeadow, C., Kim, H. N., Ryu, S., Timmers, P. R. H. J., Arbeeva, L., Dorajoo, R., Lange, L. A., Chai, X., Prasad, G., Lorés-Motta, L., Pauper, M., Long, J., Li, X., Theusch, E., Takeuchi, F., Spracklen, C. N., Loukola, A., Bollepalli, S., Warner, S. C., Wang, Y. X., Wei, W. B., Nutile, T., Ruggiero, D., Sung, Y. J., Hung, Y. J., Chen, S., Liu, F., Yang, J., Kentistou, K. A., Gorski, M., Brumat, M., Meidtner, K., Bielak, L. F., Smith, J. A., Hebbar, P., Farmaki, A. E., Hofer, E., Lin, M., Xue, C., Zhang, J., Concas, M. P., Vaccargiu, S., van der Most, P. J., Pitkänen, N., Cade, B. E., Lee, J., van der Laan, S. W., Chitrala, K. N., Weiss, S., Zimmermann, M. E., Lee, J. Y., Choi, H. S., Nethander, M., Freitag-Wolf, S., Southam, L., Rayner, N. W., Wang, C. A., Lin, S. Y., Wang, J. S., Couture, C., Lyytikäinen, L. P., Nikus, K., Cuellar-Partida, G., Vestergaard, H., Hildalgo, B., Giannakopoulou, O., Cai, Q., Obura, M. O., van Setten, J., Li, X., Schwander, K., Terzikhan, N., Shin, J. H., Jackson, R. D., Reiner, A. P., Martin, L. W., Chen, Z., Li, L., Highland, H. M., Young, K. L., Kawaguchi, T., Thiery, J., Bis, J. C., Nadkarni, G. N., Launer, L. J., Li, H., Nalls, M. A., Raitakari, O. T., Ichihara, S., Wild, S. H., Nelson, C. P., Campbell, H., Jäger, S., Nabika, T., Al-Mulla, F., Niinikoski, H., Braund, P. S., Kolcic, I., Kovacs, P., Giardoglou, T., Katsuya, T., Bhatti, K. F., de Kleijn, D., de Borst, G. J., Kim, E. K., Adams, H. H. H., Ikram, M. A., Zhu, X., Asselbergs, F. W., Kraaijeveld, A. O., Beulens, J. W. J., Shu, X. O., Rallidis, L. S., Pedersen, O., Hansen, T., Mitchell, P., Hewitt, A. W., Kähönen, M., Pérusse, L., Bouchard, C., Tönjes, A., Chen, Y. D. I., Pennell, C. E., Mori, T. A., Lieb, W., Franke, A., Ohlsson, C., Mellström, D., Cho, Y. S., Lee, H., Yuan, J. M., Koh, W. P., Rhee, S. Y., Woo, J. T., Heid, I. M., Stark, K. J., Völzke, H., Homuth, G., Evans, M. K., Zonderman, A. B., Polasek, O., Pasterkamp, G., Hoefer, I. E., Redline, S., Pahkala, K., Oldehinkel, A. J., Snieder, H., Biino, G., Schmidt, R., Schmidt, H., Chen, Y. E., Bandinelli, S., Dedoussis, G., Thanaraj, T. A., Kardia, S. L. R., Kato, N., Schulze, M. B., Girotto, G., Jung, B., Böger, C. A., Joshi, P. K., Bennett, D. A., De Jager, P. L., Lu, X., Mamakou, V., Brown, M., Caulfield, M. J., Munroe, P. B., Guo, X., Ciullo, M., Jonas, J. B., Samani, N. J., Kaprio, J., Pajukanta, P., Adair, L. S., Bechayda, S. A., de Silva, H. J., Wickremasinghe, A. R., Krauss, R. M., Wu, J. Y., Zheng, W., den Hollander, A. I., Bharadwaj, D., Correa, A., Wilson, J. G., Lind, L., Heng, C. K., Nelson, A. E., Golightly, Y. M., Wilson, J. F., Penninx, B., Kim, H. L., Attia, J., Scott, R. J., Rao, D. C., Arnett, D. K., Hunt, S. C., Walker, M., Koistinen, H. A., Chandak, G. R., Yajnik, C. S., Mercader, J. M., Tusié-Luna, T., Aguilar-Salinas, C. A., Villalpando, C. G., Orozco, L., Fornage, M., Tai, E. S., van Dam, R. M., Lehtimäki, T., Chaturvedi, N., Yokota, M., Liu, J., Reilly, D. F., McKnight, A. J., Kee, F., Jöckel, K. H., McCarthy, M. I., Palmer, C. N. A., Vitart, V., Hayward, C., Simonsick, E., van Duijn, C. M., Lu, F., Qu, J., Hishigaki, H., Lin, X., März, W., Parra, E. J., Cruz, M., Gudnason, V., Tardif, J. C., Lettre, G., ’t Hart, L. M., Elders, P. J. M., Damrauer, S. M., Kumari, M., Kivimaki, M., van der Harst, P., Spector, T. D., Loos, R. J. F., Province, M. A., Psaty, B. M., Brandslund, I., Pramstaller, P. P., Christensen, K., Ripatti, S., Widén, E., Hakonarson, H., Grant, S. F. A., Kiemeney, L. A. L. M., de Graaf, J., Loeffler, M., Kronenberg, F., Gu, D., Erdmann, J., Schunkert, H., Franks, P. W., Linneberg, A., Jukema, J. W., Khera, A. V., Männikkö, M., Jarvelin, M. R., Kutalik, Z., Cucca, F., Mook-Kanamori, D. O., van Dijk, K. W., Watkins, H., Strachan, D. P., Grarup, N., Sever, P., Poulter, N., Rotter, J. I., Dantoft, T. M., Karpe, F., Neville, M. J., Timpson, N. J., Cheng, C. Y., Wong, T. Y., Khor, C. C., Sabanayagam, C., Peters, A., Gieger, C., Hattersley, A. T., Pedersen, N. L., Magnusson, P. K. E., Boomsma, D. I., de Geus, E. J. C., Cupples, L. A., van Meurs, J. B. J., Ghanbari, M., Gordon-Larsen, P., Huang, W., Kim, Y. J., Tabara, Y., Wareham, N. J., Langenberg, C., Zeggini, E., Kuusisto, J., Laakso, M., Ingelsson, E., Abecasis, G., Chambers, J. C., Kooner, J. S., de Vries, P. S., Morrison, A. C., North, K. E., Daviglus, M., Kraft, P., Martin, N. G., Whitfield, J. B., Abbas, S., Saleheen, D., Walters, R. G., Holmes, M. V., Black, C., Smith, B. H., Justice, A. E., Baras, A., Buring, J. E., Ridker, P. M., Chasman, D. I., Kooperberg, C., Wei, W. Q., Jarvik, G. P., Namjou, B., Hayes, M. G., Ritchie, M. D., Jousilahti, P., Salomaa, V., Hveem, K., Åsvold, B. O., Kubo, M., Kamatani, Y., Okada, Y., Murakami, Y., Thorsteinsdottir, U., Stefansson, K., Ho, Y. L., Lynch, J. A., Rader, D. J., Tsao, P. S., Chang, K. M., Cho, K., O’Donnell, C. J., Gaziano, J. M., Wilson, P., Rotimi, C. N., Hazelhurst, S., Ramsay, M., Trembath, R. C., van Heel, D. A., Tamiya, G., Yamamoto, M., Kim, B. J., Mohlke, K. L., Frayling, T. M., Hirschhorn, J. N., Kathiresan, S., Boehnke, M., Natarajan, P., Peloso, G. M., Brown, C. D., Morris, A. P., Assimes, T. L., Deloukas, P., Sun, Y. V. & Willer, C. J., Jun 15 2023, In: Nature. 618, 7965, p. E19-E20

    Research output: Contribution to journalComment/debate

    Open Access
    2 Scopus citations
  • Exogenous exposures shape genetic predisposition to lipids, Alzheimer’s, and coronary heart disease in the MLXIPL gene locus

    Loika, Y., Loiko, E., Feng, F., Stallard, E., Yashin, A. I., Arbeev, K., Kuipers, A. L., Feitosa, M. F., Province, M. A. & Kulminski, A. M., 2023, In: Aging. 15, 9, p. 3249-3272 24 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Scopus citations
  • Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci

    de las Fuentes, L., Schwander, K. L., Brown, M. R., Bentley, A. R., Winkler, T. W., Sung, Y. J., Munroe, P. B., Miller, C. L., Aschard, H., Aslibekyan, S., Bartz, T. M., Bielak, L. F., Chai, J. F., Cheng, C. Y., Dorajoo, R., Feitosa, M. F., Guo, X., Hartwig, F. P., Horimoto, A., Kolčić, I., & 178 othersLim, E., Liu, Y., Manning, A. K., Marten, J., Musani, S. K., Noordam, R., Padmanabhan, S., Rankinen, T., Richard, M. A., Ridker, P. M., Smith, A. V., Vojinovic, D., Zonderman, A. B., Alver, M., Boissel, M., Christensen, K., Freedman, B. I., Gao, C., Giulianini, F., Harris, S. E., He, M., Hsu, F. C., Kühnel, B., Laguzzi, F., Li, X., Lyytikäinen, L. P., Nolte, I. M., Poveda, A., Rauramaa, R., Riaz, M., Robino, A., Sofer, T., Takeuchi, F., Tayo, B. O., van der Most, P. J., Verweij, N., Ware, E. B., Weiss, S., Wen, W., Yanek, L. R., Zhan, Y., Amin, N., Arking, D. E., Ballantyne, C., Boerwinkle, E., Brody, J. A., Broeckel, U., Campbell, A., Canouil, M., Chai, X., Chen, Y. D. I., Chen, X., Chitrala, K. N., Concas, M. P., de Faire, U., de Mutsert, R., de Silva, H. J., de Vries, P. S., Do, A., Faul, J. D., Fisher, V., Floyd, J. S., Forrester, T., Friedlander, Y., Girotto, G., Gu, C. C., Hallmans, G., Heikkinen, S., Heng, C. K., Homuth, G., Hunt, S., Ikram, M. A., Jacobs, D. R., Kavousi, M., Khor, C. C., Kilpeläinen, T. O., Koh, W. P., Komulainen, P., Langefeld, C. D., Liang, J., Liu, K., Liu, J., Lohman, K., Mägi, R., Manichaikul, A. W., McKenzie, C. A., Meitinger, T., Milaneschi, Y., Nauck, M., Nelson, C. P., O’Connell, J. R., Palmer, N. D., Pereira, A. C., Perls, T., Peters, A., Polašek, O., Raitakari, O. T., Rice, K., Rice, T. K., Rich, S. S., Sabanayagam, C., Schreiner, P. J., Shu, X. O., Sidney, S., Sims, M., Smith, J. A., Starr, J. M., Strauch, K., Tai, E. S., Taylor, K. D., Tsai, M. Y., Uitterlinden, A. G., van Heemst, D., Waldenberger, M., Wang, Y. X., Wei, W. B., Wilson, G., Xuan, D., Yao, J., Yu, C., Yuan, J. M., Zhao, W., Becker, D. M., Bonnefond, A., Bowden, D. W., Cooper, R. S., Deary, I. J., Divers, J., Esko, T., Franks, P. W., Froguel, P., Gieger, C., Jonas, J. B., Kato, N., Lakka, T. A., Leander, K., Lehtimäki, T., Magnusson, P. K. E., North, K. E., Ntalla, I., Penninx, B., Samani, N. J., Snieder, H., Spedicati, B., van der Harst, P., Völzke, H., Wagenknecht, L. E., Weir, D. R., Wojczynski, M. K., Wu, T., Zheng, W., Zhu, X., Bouchard, C., Chasman, D. I., Evans, M. K., Fox, E. R., Gudnason, V., Hayward, C., Horta, B. L., Kardia, S. L. R., Krieger, J. E., Mook-Kanamori, D. O., Peyser, P. A., Province, M. M., Psaty, B. M., Rudan, I., Sim, X., Smith, B. H., van Dam, R. M., van Duijn, C. M., Wong, T. Y., Arnett, D. K., Rao, D. C., Gauderman, J., Liu, C. T., Morrison, A. C., Rotter, J. I. & Fornage, M., 2023, In: Frontiers in Genetics. 14, 1235337.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Genome-wide association analysis identifies ancestry-specific genetic variation associated with acute response to metformin and glipizide in SUGAR-MGH

    MAGIC Investigators, Diabetes Prevention Program (DPP) Research Group, Province, M. A., White, N. H. & Brown, A. L., Jul 2023, In: Diabetologia. 66, 7, p. 1260-1272 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Scopus citations
  • Genome-wide association meta-analysis identifies 17 loci associated with nonalcoholic fatty liver disease

    Chen, Y., Du, X., Kuppa, A., Feitosa, M. F., Bielak, L. F., O’Connell, J. R., Musani, S. K., Guo, X., Kahali, B., Chen, V. L., Smith, A. V., Ryan, K. A., Eirksdottir, G., Allison, M. A., Bowden, D. W., Budoff, M. J., Carr, J. J., Chen, Y. D. I., Taylor, K. D., Oliveri, A., & 17 othersCorrea, A., Crudup, B. F., Kardia, S. L. R., Mosley, T. H., Norris, J. M., Terry, J. G., Rotter, J. I., Wagenknecht, L. E., Halligan, B. D., Young, K. A., Hokanson, J. E., Washko, G. R., Gudnason, V., Province, M. A., Peyser, P. A., Palmer, N. D. & Speliotes, E. K., Oct 2023, In: Nature Genetics. 55, 10, p. 1640-1650 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    20 Scopus citations
  • The Type 2 Diabetes Knowledge Portal: An open access genetic resource dedicated to type 2 diabetes and related traits

    AMP-T2D Consortium, Apr 4 2023, In: Cell metabolism. 35, 4, p. 695-710.e6

    Research output: Contribution to journalArticlepeer-review

    Open Access
    25 Scopus citations
  • Whole-exome sequence analysis of anthropometric traits illustrates challenges in identifying effects of rare genetic variants

    Young, K. L., Fisher, V., Deng, X., Brody, J. A., Graff, M., Lim, E., Lin, B. M., Xu, H., Amin, N., An, P., Aslibekyan, S., Fohner, A. E., Hidalgo, B., Lenzini, P., Kraaij, R., Medina-Gomez, C., Prokić, I., Rivadeneira, F., Sitlani, C., Tao, R., & 42 othersvan Rooij, J., Zhang, D., Broome, J. G., Buth, E. J., Heavner, B. D., Jain, D., Smith, A. V., Barnes, K., Boorgula, M. P., Chavan, S., Darbar, D., De Andrade, M., Guo, X., Haessler, J., Irvin, M. R., Kalyani, R. R., Kardia, S. L. R., Kooperberg, C., Kim, W., Mathias, R. A., McDonald, M. L., Mitchell, B. D., Peyser, P. A., Regan, E. A., Redline, S., Reiner, A. P., Rich, S. S., Rotter, J. I., Smith, J. A., Weiss, S., Wiggins, K. L., Yanek, L. R., Arnett, D., Heard-Costa, N. L., Leal, S., Lin, D., McKnight, B., Province, M., van Duijn, C. M., North, K. E., Cupples, L. A. & Liu, C. T., Jan 12 2023, In: Human Genetics and Genomics Advances. 4, 1, 100163.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    2 Scopus citations
  • 2022

    A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids

    Million Veterans Program, Global Lipids Genetics Consortium, Locke, A. E., Wojczynski, M. K., Sung, Y. J., Rao, D. C. & Province, M. A., Aug 4 2022, In: American journal of human genetics. 109, 8, p. 1366-1387 22 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    14 Scopus citations
  • A saturated map of common genetic variants associated with human height

    23andMe Research Team, VA Million Veteran Program, DiscovEHR (DiscovEHR and MyCode Community Health Initiative), eMERGE (Electronic Medical Records and Genomics Network), Lifelines Cohort Study, The PRACTICAL Consortium & Understanding Society Scientific group, Oct 27 2022, In: Nature. 610, 7933, p. 704-712 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    161 Scopus citations
  • Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals

    Lifelines Cohort Study, DiscovEHR/MyCode study, VA Million Veteran Program, Wojczynski, M. K. & Province, M. A., Dec 1 2022, In: Communications Biology. 5, 1, 580.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    16 Scopus citations
  • Gene-lifestyle interactions in the genomics of human complex traits

    the CHARGE Gene-Lifestyle Interactions Working Group, Jun 2022, In: European Journal of Human Genetics. 30, 6, p. 730-739 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    11 Scopus citations
  • Genome-wide analysis of mitochondrial DNA copy number reveals loci implicated in nucleotide metabolism, platelet activation, and megakaryocyte proliferation

    Longchamps, R. J., Yang, S. Y., Castellani, C. A., Shi, W., Lane, J., Grove, M. L., Bartz, T. M., Sarnowski, C., Liu, C., Burrows, K., Guyatt, A. L., Gaunt, T. R., Kacprowski, T., Yang, J., De Jager, P. L., Yu, L., Bergman, A., Xia, R., Fornage, M., Feitosa, M. F., & 32 othersWojczynski, M. K., Kraja, A. T., Province, M. A., Amin, N., Rivadeneira, F., Tiemeier, H., Uitterlinden, A. G., Broer, L., Van Meurs, J. B. J., Van Duijn, C. M., Raffield, L. M., Lange, L., Rich, S. S., Lemaitre, R. N., Goodarzi, M. O., Sitlani, C. M., Mak, A. C. Y., Bennett, D. A., Rodriguez, S., Murabito, J. M., Lunetta, K. L., Sotoodehnia, N., Atzmon, G., Ye, K., Barzilai, N., Brody, J. A., Psaty, B. M., Taylor, K. D., Rotter, J. I., Boerwinkle, E., Pankratz, N. & Arking, D. E., Jan 2022, In: Human genetics. 141, 1, p. 127-146 20 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    24 Scopus citations
  • Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis

    Kanoni, S., Graham, S. E., Wang, Y., Surakka, I., Ramdas, S., Zhu, X., Clarke, S. L., Bhatti, K. F., Vedantam, S., Winkler, T. W., Locke, A. E., Marouli, E., Zajac, G. J. M., Wu, K. H. H., Ntalla, I., Hui, Q., Klarin, D., Hilliard, A. T., Wang, Z., Xue, C., & 519 othersThorleifsson, G., Helgadottir, A., Gudbjartsson, D. F., Holm, H., Olafsson, I., Hwang, M. Y., Han, S., Akiyama, M., Sakaue, S., Terao, C., Kanai, M., Zhou, W., Brumpton, B. M., Rasheed, H., Havulinna, A. S., Veturi, Y., Pacheco, J. A., Rosenthal, E. A., Lingren, T., Feng, Q. P., Kullo, I. J., Narita, A., Takayama, J., Martin, H. C., Hunt, K. A., Trivedi, B., Haessler, J., Giulianini, F., Bradford, Y., Miller, J. E., Campbell, A., Lin, K., Millwood, I. Y., Rasheed, A., Hindy, G., Faul, J. D., Zhao, W., Weir, D. R., Turman, C., Huang, H., Graff, M., Choudhury, A., Sengupta, D., Mahajan, A., Brown, M. R., Zhang, W., Yu, K., Schmidt, E. M., Pandit, A., Gustafsson, S., Yin, X., Luan, J., Zhao, J. H., Matsuda, F., Jang, H. M., Yoon, K., Medina-Gomez, C., Pitsillides, A., Hottenga, J. J., Wood, A. R., Ji, Y., Gao, Z., Haworth, S., Yousri, N. A., Mitchell, R. E., Chai, J. F., Aadahl, M., Bjerregaard, A. A., Yao, J., Manichaikul, A., Hwu, C. M., Hung, Y. J., Warren, H. R., Ramirez, J., Bork-Jensen, J., Kårhus, L. L., Goel, A., Sabater-Lleal, M., Noordam, R., Mauro, P., Matteo, F., McDaid, A. F., Marques-Vidal, P., Wielscher, M., Trompet, S., Sattar, N., Møllehave, L. T., Munz, M., Zeng, L., Huang, J., Yang, B., Poveda, A., Kurbasic, A., Lamina, C., Forer, L., Scholz, M., Galesloot, T. E., Bradfield, J. P., Ruotsalainen, S. E., Daw, EW. W., Zmuda, J. M., Mitchell, J. S., Fuchsberger, C., Christensen, H., Brody, J. A., Vazquez-Moreno, M., Feitosa, M. F., Wojczynski, M. K., Wang, Z., Preuss, M. H., Mangino, M., Christofidou, P., Verweij, N., Benjamins, J. W., Engmann, J., Tsao, N. L., Verma, A., Slieker, R. C., Lo, K. S., Zilhao, N. R., Le, P., Kleber, M. E., Delgado, G. E., Huo, S., Ikeda, D. D., Iha, H., Yang, J., Liu, J., Demirkan, A., Leonard, H. L., Marten, J., Frank, M., Schmidt, B., Smyth, L. J., Cañadas-Garre, M., Wang, C., Nakatochi, M., Wong, A., Hutri-Kähönen, N., Sim, X., Xia, R., Huerta-Chagoya, A., Fernandez-Lopez, J. C., Lyssenko, V., Nongmaithem, S. S., Bayyana, S., Stringham, H. M., Irvin, M. R., Oldmeadow, C., Kim, H. N., Ryu, S., Timmers, P. R. H. J., Arbeeva, L., Dorajoo, R., Lange, L. A., Prasad, G., Lorés-Motta, L., Pauper, M., Long, J., Li, X., Theusch, E., Takeuchi, F., Spracklen, C. N., Loukola, A., Bollepalli, S., Warner, S. C., Wang, Y. X., Wei, W. B., Nutile, T., Ruggiero, D., Sung, Y. J., Chen, S., Liu, F., Yang, J., Kentistou, K. A., Banas, B., Nardone, G. G., Meidtner, K., Bielak, L. F., Smith, J. A., Hebbar, P., Farmaki, A. E., Hofer, E., Lin, M., Concas, M. P., Vaccargiu, S., van der Most, P. J., Pitkänen, N., Cade, B. E., van der Laan, S. W., Chitrala, K. N., Weiss, S., Bentley, A. R., Doumatey, A. P., Adeyemo, A. A., Lee, J. Y., Petersen, E. R. B., Nielsen, A. A., Choi, H. S., Nethander, M., Freitag-Wolf, S., Southam, L., Rayner, N. W., Wang, C. A., Lin, S. Y., Wang, J. S., Couture, C., Lyytikäinen, L. P., Nikus, K., Cuellar-Partida, G., Vestergaard, H., Hidalgo, B., Giannakopoulou, O., Cai, Q., Obura, M. O., van Setten, J., Li, X., Liang, J., Tang, H., Terzikhan, N., Shin, J. H., Jackson, R. D., Reiner, A. P., Martin, L. W., Chen, Z., Li, L., Kawaguchi, T., Thiery, J., Bis, J. C., Launer, L. J., Li, H., Nalls, M. A., Raitakari, O. T., Ichihara, S., Wild, S. H., Nelson, C. P., Campbell, H., Jäger, S., Nabika, T., Al-Mulla, F., Niinikoski, H., Braund, P. S., Kolcic, I., Kovacs, P., Giardoglou, T., Katsuya, T., de Kleijn, D., de Borst, G. J., Kim, E. K., Adams, H. H. H., Ikram, M. A., Zhu, X., Asselbergs, F. W., Kraaijeveld, A. O., Beulens, J. W. J., Shu, X. O., Rallidis, L. S., Pedersen, O., Hansen, T., Mitchell, P., Hewitt, A. W., Kähönen, M., Pérusse, L., Bouchard, C., Tönjes, A., Chen, Y. D. I., Pennell, C. E., Mori, T. A., Lieb, W., Franke, A., Ohlsson, C., Mellström, D., Cho, Y. S., Lee, H., Yuan, J. M., Koh, W. P., Rhee, S. Y., Woo, J. T., Heid, I. M., Stark, K. J., Zimmermann, M. E., Völzke, H., Homuth, G., Evans, M. K., Zonderman, A. B., Polasek, O., Pasterkamp, G., Hoefer, I. E., Redline, S., Pahkala, K., Oldehinkel, A. J., Snieder, H., Biino, G., Schmidt, R., Schmidt, H., Bandinelli, S., Dedoussis, G., Thanaraj, T. A., Kardia, S. L. R., Peyser, P. A., Kato, N., Schulze, M. B., Girotto, G., Böger, C. A., Jung, B., Joshi, P. K., Bennett, D. A., De Jager, P. L., Lu, X., Mamakou, V., Brown, M., Caulfield, M. J., Munroe, P. B., Guo, X., Ciullo, M., Jonas, J. B., Samani, N. J., Kaprio, J., Pajukanta, P., Tusié-Luna, T., Aguilar-Salinas, C. A., Adair, L. S., Bechayda, S. A., de Silva, H. J., Wickremasinghe, A. R., Krauss, R. M., Wu, J. Y., Zheng, W., Hollander, A. I., Bharadwaj, D., Correa, A., Wilson, J. G., Lind, L., Heng, C. K., Nelson, A. E., Golightly, Y. M., Wilson, J. F., Penninx, B., Kim, H. L., Attia, J., Scott, R. J., Rao, D. C., Arnett, D. K., Hunt, S. C., Walker, M., Koistinen, H. A., Chandak, G. R., Mercader, J. M., Costanzo, M. C., Jang, D., Burtt, N. P., Villalpando, C. G., Orozco, L., Fornage, M., Tai, ES. S., van Dam, R. M., Lehtimäki, T., Chaturvedi, N., Yokota, M., Liu, J., Reilly, D. F., McKnight, A. J., Kee, F., Jöckel, K. H., McCarthy, M. I., Palmer, C. N. A., Vitart, V., Hayward, C., Simonsick, E., van Duijn, C. M., Jin, Z. B., Qu, J., Hishigaki, H., Lin, X., März, W., Gudnason, V., Tardif, J. C., Lettre, G., Hart, L. M. ., Elders, P. J. M., Damrauer, S. M., Kumari, M., Kivimaki, M., van der Harst, P., Spector, T. D., Loos, R. J. F., Province, M. A., Parra, E. J., Cruz, M., Psaty, B. M., Brandslund, I., Pramstaller, P. P., Rotimi, C. N., Christensen, K., Ripatti, S., Widén, E., Hakonarson, H., Grant, S. F. A., Kiemeney, L. A. L. M., de Graaf, J., Loeffler, M., Kronenberg, F., Gu, D., Erdmann, J., Schunkert, H., Franks, P. W., Linneberg, A., Jukema, J. W., Khera, A. V., Männikkö, M., Jarvelin, M. R., Kutalik, Z., Francesco, C., Mook-Kanamori, D. O., van Dijk, K. W., Watkins, H., Strachan, D. P., Grarup, N., Sever, P., Poulter, N., Chuang, L. M., Rotter, J. I., Dantoft, T. M., Karpe, F., Neville, M. J., Timpson, N. J., Cheng, C. Y., Wong, T. Y., Khor, C. C., Li, H., Sabanayagam, C., Peters, A., Gieger, C., Hattersley, A. T., Pedersen, N. L., Magnusson, P. K. E., Boomsma, D. I., Willemsen, A. H. M., Cupples, LA. A., van Meurs, J. B. J., Ghanbari, M., Gordon-Larsen, P., Huang, W., Kim, Y. J., Tabara, Y., Wareham, N. J., Langenberg, C., Zeggini, E., Kuusisto, J., Laakso, M., Ingelsson, E., Abecasis, G., Chambers, J. C., Kooner, J. S., de Vries, P. S., Morrison, A. C., Hazelhurst, S., Ramsay, M., North, K. E., Daviglus, M., Kraft, P., Martin, N. G., Whitfield, J. B., Abbas, S., Saleheen, D., Walters, R. G., Holmes, M. V., Black, C., Smith, B. H., Baras, A., Justice, A. E., Buring, J. E., Ridker, P. M., Chasman, D. I., Kooperberg, C., Tamiya, G., Yamamoto, M., van Heel, D. A., Trembath, R. C., Wei, W. Q., Jarvik, G. P., Namjou, B., Hayes, M. G., Ritchie, M. D., Jousilahti, P., Salomaa, V., Hveem, K., Åsvold, B. O., Kubo, M., Kamatani, Y., Okada, Y., Murakami, Y., Kim, B. J., Thorsteinsdottir, U., Stefansson, K., Zhang, J., Chen, YE. E., Ho, Y. L., Lynch, J. A., Rader, D. J., Tsao, P. S., Chang, K. M., Cho, K., O’Donnell, C. J., Gaziano, J. M., Wilson, P. W. F., Frayling, T. M., Hirschhorn, J. N., Kathiresan, S., Mohlke, K. L., Sun, Y. V., Morris, A. P., Boehnke, M., Brown, C. D., Natarajan, P., Deloukas, P., Willer, C. J., Assimes, T. L. & Peloso, G. M., Dec 2022, In: Genome biology. 23, 1, 268.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    18 Scopus citations
  • Longitudinal Association Between Muscle Loss and Mortality in Ever Smokers

    COPDGene Investigators, Apr 1 2022, In: CHEST. 161, 4, p. 960-970 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    19 Scopus citations
  • Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

    FinnGen & eMERGE Consortium, May 1 2022, In: Nature Genetics. 54, 5, p. 560-572 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    190 Scopus citations
  • Multi-omics insights into the biological mechanisms underlying statistical gene-by-lifestyle interactions with smoking and alcohol consumption

    on behalf of the CHARGE Gene-Lifestyle Interactions Working Group, Dec 5 2022, In: Frontiers in Genetics. 13, 954713.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    2 Scopus citations
  • NIA Long Life Family Study: Objectives, Design, and Heritability of Cross-Sectional and Longitudinal Phenotypes

    Wojczynski, M. K., Jiuan Lin, S., Sebastiani, P., Perls, T. T., Lee, J., Kulminski, A., Newman, A., Zmuda, J. M., Christensen, K. & Province, M. A., Apr 1 2022, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 77, 4, p. 717-727 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    17 Scopus citations
  • Obesity Partially Mediates the Diabetogenic Effect of Lowering LDL Cholesterol

    Wu, P., Moon, J. Y., Daghlas, I., Franco, G., Porneala, B. C., Ahmadizar, F., Richardson, T. G., Isaksen, J. L., Hindy, G., Yao, J., Sitlani, C. M., Raffield, L. M., Yanek, L. R., Feitosa, M. F., Cuadrat, R. R. C., Qi, Q., Ikram, M. A., Ellervik, C., Ericson, U., Goodarzi, M. O., & 32 othersBrody, J. A., Lange, L., Mercader, J. M., Vaidya, D., An, P., Schulze, M. B., Masana, L., Ghanbari, M., Olesen, M. S., Cai, J., Guo, X., Floyd, J. S., Jager, S., Province, M. A., Kalyani, R. R., Psaty, B. M., Orho-Melander, M., Ridker, P. M., Kanters, J. K., Uitterlinden, A., Smith, G. D., Gill, D., Kaplan, R. C., Kavousi, M., Raghavan, S., Chasman, D. I., Rotter, J. I., Meigs, J. B., Florez, J. C., Dupuis, J., Liu, C. T. & Merino, J., Jan 2022, In: Diabetes care. 45, 1, p. 232-240 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    7 Scopus citations
  • Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals

    23andMe Research Team, Social Science Genetic Association Consortium & Lifelines Cohort Study, Apr 2022, In: Nature Genetics. 54, 4, p. 437-449 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    185 Scopus citations
  • 2021

    Allele-specific variation at APOE increases nonalcoholic fatty liver disease and obesity but decreases risk of Alzheimer's disease and myocardial infarction

    Palmer, N. D., Kahali, B., Kuppa, A., Chen, Y., Du, X., Feitosa, M. F., Bielak, L. F., O'Connell, J. R., Musani, S. K., Guo, X., Smith, A. V., Ryan, K. A., Eirksdottir, G., Allison, M. A., Bowden, D. W., Budoff, M. J., Carr, J. J., Chen, Y. D. I., Taylor, K. D., Correa, A., & 16 othersCrudup, B. F., Halligan, B., Yang, J., Kardia, S. L. R., Launer, L. J., Fu, Y. P., Mosley, T. H., Norris, J. M., Terry, J. G., O'Donnell, C. J., Rotter, J. I., Wagenknecht, L. E., Gudnason, V., Province, M. A., Peyser, P. A. & Speliotes, E. K., Aug 1 2021, In: Human molecular genetics. 30, 15, p. 1443-1456 14 p.

    Research output: Contribution to journalArticlepeer-review

    19 Scopus citations
  • A Noncoding Variant near PPP1R3B Promotes Liver Glycogen Storage and MetS, but Protects against Myocardial Infarction

    Kahali, B., Chen, Y., Feitosa, M. F., Bielak, L. F., Oconnell, J. R., Musani, S. K., Hegde, Y., Chen, Y., Stetson, L. C., Guo, X., Fu, Y. P., Smith, A. V., Ryan, K. A., Eiriksdottir, G., Cohain, A. T., Allison, M., Bakshi, A., Bowden, D. W., Budoff, M. J., Carr, J. J., & 26 othersCarskadon, S., Chen, Y. D. I., Correa, A., Crudup, B. F., Du, X., Harris, T. B., Yang, J., Kardia, S. L. R., Launer, L. J., Liu, J., Mosley, T. H., Norris, J. M., Terry, J. G., Palanisamy, N., Schadt, E. E., O'Donnell, C. J., Yerges-Armstrong, L. M., Rotter, J. I., Wagenknecht, L. E., Handelman, S. K., Gudnason, V., Province, M. A., Peyser, P. A., Halligan, B., Palmer, N. D. & Speliotes, E. K., Feb 1 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 2, p. 372-387 16 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    8 Scopus citations
  • Combined effect of lead exposure and allostatic load on cardiovascular disease mortality—A preliminary study

    Obeng-Gyasi, E., Ferguson, A. C., Stamatakis, K. A. & Province, M. A., Jul 1 2021, In: International journal of environmental research and public health. 18, 13, 6879.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    21 Scopus citations
  • Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci

    Lifelines Cohort Study, Jun 2021, In: Molecular Psychiatry. 26, 6, p. 2111-2125 15 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    13 Scopus citations
  • Heterogeneity of the Predictive Polygenic Risk Scores for Coronary Heart Disease Age-at-Onset in Three Different Coronary Heart Disease Family-Based Ascertainments

    Feitosa, M. F., Kuipers, A. L., Wojczynski, M. K., Wang, L., Barinas-Mitchell, E., Kulminski, A. M., Thyagarajan, B., Lee, J. H., Perls, T., Christensen, K., Newman, A. B., Zmuda, J. M. & Province, M. A., Jun 1 2021, In: Circulation: Genomic and Precision Medicine. 14, 3, p. E003201

    Research output: Contribution to journalArticlepeer-review

    Open Access
    3 Scopus citations
  • Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability (Nature Communications, (2021), 12, 1, (24), 10.1038/s41467-020-19366-9)

    Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC), Dec 1 2021, In: Nature communications. 12, 1, 995.

    Research output: Contribution to journalComment/debate

    Open Access
    5 Scopus citations
  • Publisher Correction: Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals (Nature Genetics, (2020), 52, 12, (1314-1332), 10.1038/s41588-020-00713-x)

    Lifelines Cohort Study, EPIC-CVD, EPIC-InterAct, Understanding Society Scientific group & Million Veteran Program, May 1 2021, In: Nature Genetics. 53, 5, p. 762 1 p.

    Research output: Contribution to journalComment/debate

    Open Access
  • Publisher Correction: A meta-analysis of genome-wide association studies identifies multiple longevity genes (Nature Communications, (2019), 10, 1, (3669), 10.1038/s41467-019-11558-2)

    Deelen, J., Evans, D. S., Arking, D. E., Tesi, N., Nygaard, M., Liu, X., Wojczynski, M. K., Biggs, M. L., van der Spek, A., Atzmon, G., Ware, E. B., Sarnowski, C., Smith, A. V., Seppälä, I., Cordell, H. J., Dose, J., Amin, N., Arnold, A. M., Ayers, K. L., Barzilai, N., & 64 othersBecker, E. J., Beekman, M., Blanché, H., Christensen, K., Christiansen, L., Collerton, J. C., Cubaynes, S., Cummings, S. R., Davies, K., Debrabant, B., Deleuze, J. F., Duncan, R., Faul, J. D., Franceschi, C., Galan, P., Gudnason, V., Harris, T. B., Huisman, M., Hurme, M. A., Jagger, C., Jansen, I., Jylhä, M., Kähönen, M., Karasik, D., Kardia, S. L. R., Kingston, A., Kirkwood, T. B. L., Launer, L. J., Lehtimäki, T., Lieb, W., Lyytikäinen, L. P., Martin-Ruiz, C., Min, J., Nebel, A., Newman, A. B., Nie, C., Nohr, E. A., Orwoll, E. S., Perls, T. T., Province, M. A., Psaty, B. M., Raitakari, O. T., Reinders, M. J. T., Robine, J. M., Rotter, J. I., Sebastiani, P., Smith, J., Sørensen, T. I. A., Taylor, K. D., Uitterlinden, A. G., van der Flier, W., van der Lee, S. J., van Duijn, C. M., van Heemst, D., Vaupel, J. W., Weir, D., Ye, K., Zeng, Y., Zheng, W., Holstege, H., Kiel, D. P., Lunetta, K. L., Slagboom, P. E. & Murabito, J. M., Dec 1 2021, In: Nature communications. 12, 1, 2463.

    Research output: Contribution to journalComment/debate

    Open Access
    2 Scopus citations
  • Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability

    Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC), Dec 1 2021, In: Nature communications. 12, 1, 24.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    83 Scopus citations
  • The power of genetic diversity in genome-wide association studies of lipids

    VA Million Veteran Program & Global Lipids Genetics Consortium*, Dec 23 2021, In: Nature. 600, 7890, p. 675-679 5 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    275 Scopus citations
  • The trans-ancestral genomic architecture of glycemic traits

    Lifelines Cohort Study & Meta-Analysis of Glucose and Insulin-related Traits Consortium (MAGIC), Jun 1 2021, In: Nature Genetics. 53, 6, p. 840-860 21 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    283 Scopus citations
  • 2020

    A comparison of genetic imputation methods using Long Life Family Study genotypes and sequence data with the 1000 Genome reference panel

    Kraja, A. T., Warwick Daw, E., Lenzini, P., Wang, L., Lin, S. J., Williams, C. A., Wells, A. B., Lunetta, K. L., Murabito, J. M., Sebastiani, P., Tosto, G., Barral, S., Minster, R. L., Yashin, A., Perls, T. & Province, M. A., 2020, In: International Journal of Bioinformatics Research and Applications. 16, 1, p. 59-84 26 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Carbohydrate and fat intake associated with risk of metabolic diseases through epigenetics of CPT1A

    Lai, C. Q., Parnell, L. D., Smith, C. E., Guo, T., Sayols-Baixeras, S., Aslibekyan, S., Tiwari, H. K., Irvin, M. R., Bender, C., Fei, D., Hidalgo, B., Hopkins, P. N., Absher, D. M., Province, M. A., Elosua, R., Arnett, D. K. & Ordovas, J. M., Nov 1 2020, In: American Journal of Clinical Nutrition. 112, 5, p. 1200-1211 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    48 Scopus citations
  • Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

    Lifelines Cohort Study, EPIC-CVD, EPIC-InterAct, Understanding Society Scientific group & Million Veteran Program, Dec 1 2020, In: Nature Genetics. 52, 12, p. 1314-1332 19 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    81 Scopus citations
  • Gene discovery for high-density lipoprotein cholesterol level change over time in prospective family studies

    Feitosa, M. F., Lunetta, K. L., Wang, L., Wojczynski, M. K., Kammerer, C. M., Perls, T., Schupf, N., Christensen, K., Murabito, J. M. & Province, M. A., Mar 2020, In: Atherosclerosis. 297, p. 102-110 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    5 Scopus citations
  • Genetics and geography of leukocyte telomere length in sub-Saharan Africans

    Hunt, S. C., Hansen, M. E. B., Verhulst, S., McQuillan, M. A., Beggs, W., Lai, T. P., Mokone, G. G., Mpoloka, S. W., Meskel, D. W., Belay, G., Nyambo, T. B., Abnet, C. C., Yeager, M., Chanock, S. J., Province, M. A., Williams, S. M., Aviv, A. & Tishkoff, S. A., Sep 15 2020, In: Human molecular genetics. 29, 18, p. 3014-3020 7 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    6 Scopus citations
  • Genetic studies of leptin concentrations implicate leptin in the regulation of early adiposity

    Yaghootkar, H., Zhang, Y., Spracklen, C. N., Karaderi, T., Huang, L. O., Bradfield, J., Schurmann, C., Fine, R. S., Preuss, M. H., Kutalik, Z., Wittemans, L. B. L., Lu, Y., Metz, S., Willems, S. M., Li-Gao, R., Grarup, N., Wang, S., Molnos, S., Sandoval-Zárate, A. A., Nalls, M. A., & 96 othersLange, L. A., Haesser, J., Guo, X., Lyytikäinen, L. P., Feitosa, M. F., Sitlani, C. M., Venturini, C., Mahajan, A., Kacprowski, T., Wang, C. A., Chasman, D. I., Amin, N., Broer, L., Robertson, N., Young, K. L., Allison, M., Auer, P. L., Blüher, M., Borja, J. B., Bork-Jensen, J., Carrasquilla, G. D., Christofidou, P., Demirkan, A., Doege, C. A., Garcia, M. E., Graff, M., Guo, K., Hakonarson, H., Hong, J., Chen, Y. D. I., Jackson, R., Jakupovic, H., Jousilahti, P., Justice, A. E., Kähönen, M., Kizer, J. R., Kriebel, J., Leduc, C. A., Li, J., Lind, L., Luan, JA., Mackey, D. A., Mangino, M., Männistö, S., Carli, J. F. M., Medina-Gomez, C., Mook-Kanamori, D. O., Morris, A. P., de Mutsert, R., Nauck, M., Prokic, I., Pennell, C. E., Pradhan, A. D., Psaty, B. M., Raitakari, O. T., Scott, R. A., Skaaby, T., Strauch, K., Taylor, K. D., Teumer, A., Uitterlinden, A. G., Wu, Y., Yao, J., Walker, M., North, K. E., Kovacs, P., Ikram, M. A., van Duijn, C. M., Ridker, P. M., Lye, S., Homuth, G., Ingelsson, E., Spector, T. D., McKnight, B., Province, M. A., Lehtimäki, T., Adair, L. S., Rotter, J. I., Reiner, A. P., Wilson, J. G., Harris, T. B., Ripatti, S., Grallert, H., Meigs, J. B., Salomaa, V., Hansen, T., van Dijk, K. W., Wareham, N. J., Grant, S. F. A., Langenberg, C., Frayling, T. M., Lindgren, C. M., Mohlke, K. L., Leibel, R. L., Loos, R. J. F. & Kilpeläinen, T. O., Dec 2020, In: Diabetes. 69, 12, p. 2806-2818 13 p.

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    22 Scopus citations
  • Leukocyte Telomere Length Is Unrelated to Cognitive Performance among Non-Demented and Demented Persons: An Examination of Long Life Family Study Participants

    Ashrafi, A., Cosentino, S., Kang, M. S., Lee, J. H., Schupf, N., Andersen, S. L., Christensen, K., Province, M. A., Thyagarajan, B., Zmuda, J. M. & Honig, L. S., Oct 1 2020, In: Journal of the International Neuropsychological Society. 26, 9, p. 906-917 12 p.

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    4 Scopus citations
  • Mechanisms underlying familial aggregation of exceptional health and survival: A three-generation cohort study

    Christensen, K., Wojczynski, M. K., Pedersen, J. K., Larsen, L. A., Kløjgaard, S., Skytthe, A., McGue, M., Vaupel, J. W. & Province, M. A., Oct 1 2020, In: Aging Cell. 19, 10, e13228.

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    Open Access
    11 Scopus citations
  • Role of Rare and Low-Frequency Variants in Gene-Alcohol Interactions on Plasma Lipid Levels

    Wang, Z., Chen, H., Bartz, T. M., Bielak, L. F., Chasman, D. I., Feitosa, M. F., Franceschini, N., Guo, X., Lim, E., Noordam, R., Richard, M. A., Wang, H., Cade, B., Cupples, L. A., De Vries, P. S., Giulanini, F., Lee, J., Lemaitre, R. N., Martin, L. W., Reiner, A. P., & 20 othersRich, S. S., Schreiner, P. J., Sidney, S., Sitlani, C. M., Smith, J. A., Willems Van Dijk, K., Yao, J., Zhao, W., Fornage, M., Kardia, S. L. R., Kooperberg, C., Liu, C. T., Mook-Kanamori, D. O., Province, M. A., Psaty, B. M., Redline, S., Ridker, P. M., Rotter, J. I., Boerwinkle, E. & Morrison, A. C., Aug 1 2020, In: Circulation: Genomic and Precision Medicine. 13, 4, p. E002772

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    10 Scopus citations
  • Salivary AMY1 Copy Number Variation Modifies Age-Related Type 2 Diabetes Risk

    Liu, Y., Smith, C. E., Parnell, L. D., Lee, Y. C., An, P., Straka, R. J., Tiwari, H. K., Wood, A. C., Kabagambe, E. K., Hidalgo, B., Hopkins, P. N., Province, M. A., Arnett, D. K., Tucker, K. L., Ordovas, J. M. & Lai, C. Q., May 1 2020, In: Clinical chemistry. 66, 5, p. 718-726 9 p.

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    5 Scopus citations
  • Smoking-by-genotype interaction in type 2 diabetes risk and fasting glucose

    Wu, P., Rybin, D., Bielak, L. F., Feitosa, M. F., Franceschini, N., Li, Y., Lu, Y., Marten, J., Musani, S. K., Noordam, R., Raghavan, S., Rose, L. M., Schwander, K., Smith, A. V., Tajuddin, S. M., Vojinovic, D., Amin, N., Arnett, D. K., Bottinger, E. P., Demirkan, A., & 38 othersFlorez, J. C., Ghanbari, M., Harris, T. B., Launer, L. J., Liu, J., Liu, J., Mook-Kanamori, D. O., Murray, A. D., Nalls, M. A., Peyser, P. A., Uitterlinden, A. G., Voortman, T., Bouchard, C., Chasman, D., Correa, A., de Mutsert, R., Evans, M. K., Gudnason, V., Hayward, C., Kao, L., Kardia, S. L. R., Kooperberg, C., Loos, R. J. F., Province, M. M., Rankinen, T., Redline, S., Ridker, P. M., Rotter, J. I., Siscovick, D., Smith, B. H., van Duijn, C., Zonderman, A. B., Rao, D. C., Wilson, J. G., Dupuis, J., Meigs, J. B., Liu, C. T. & Vassy, J. L., May 2020, In: PloS one. 15, 5, e0230815.

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    11 Scopus citations
  • 2019

    A catalog of genetic loci associated with kidney function from analyses of a million individuals

    Lifelines Cohort Study & V. A. Million Veteran Program, Jun 1 2019, In: Nature Genetics. 51, 6, p. 957-972 16 p.

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    444 Scopus citations
  • A meta-analysis of genome-wide association studies identifies multiple longevity genes

    Deelen, J., Evans, D. S., Arking, D. E., Tesi, N., Nygaard, M., Liu, X., Wojczynski, M. K., Biggs, M. L., van der Spek, A., Atzmon, G., Ware, E. B., Sarnowski, C., Smith, A. V., Seppälä, I., Cordell, H. J., Dose, J., Amin, N., Arnold, A. M., Ayers, K. L., Barzilai, N., & 64 othersBecker, E. J., Beekman, M., Blanché, H., Christensen, K., Christiansen, L., Collerton, J. C., Cubaynes, S., Cummings, S. R., Davies, K., Debrabant, B., Deleuze, J. F., Duncan, R., Faul, J. D., Franceschi, C., Galan, P., Gudnason, V., Harris, T. B., Huisman, M., Hurme, M. A., Jagger, C., Jansen, I., Jylhä, M., Kähönen, M., Karasik, D., Kardia, S. L. R., Kingston, A., Kirkwood, T. B. L., Launer, L. J., Lehtimäki, T., Lieb, W., Lyytikäinen, L. P., Martin-Ruiz, C., Min, J., Nebel, A., Newman, A. B., Nie, C., Nohr, E. A., Orwoll, E. S., Perls, T. T., Province, M. A., Psaty, B. M., Raitakari, O. T., Reinders, M. J. T., Robine, J. M., Rotter, J. I., Sebastiani, P., Smith, J., Sørensen, T. I. A., Taylor, K. D., Uitterlinden, A. G., van der Flier, W., van der Lee, S. J., van Duijn, C. M., van Heemst, D., Vaupel, J. W., Weir, D., Ye, K., Zeng, Y., Zheng, W., Holstege, H., Kiel, D. P., Lunetta, K. L., Slagboom, P. E. & Murabito, J. M., Dec 1 2019, In: Nature communications. 10, 1, 3669.

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    196 Scopus citations
  • A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

    Sung, Y. J., De Las Fuentes, L., Winkler, T. W., Chasman, D. I., Bentley, A. R., Kraja, A. T., Ntalla, I., Warren, H. R., Guo, X., Schwander, K., Manning, A. K., Brown, M. R., Aschard, H., Feitosa, M. F., Franceschini, N., Lu, Y., Cheng, C. Y., Sim, X., Vojinovic, D., Marten, J., & 261 othersMusani, S. K., Kilpeläinen, T. O., Richard, M. A., Aslibekyan, S., Bartz, T. M., Dorajoo, R., Li, C., Liu, Y., Rankinen, T., Smith, A. V., Tajuddin, S. M., Tayo, B. O., Zhao, W., Zhou, Y., Matoba, N., Sofer, T., Alver, M., Amini, M., Boissel, M., Chai, J. F., Chen, X., Divers, J., Gandin, I., Gao, C., Giulianini, F., Goel, A., Harris, S. E., Hartwig, F. P., He, M., Horimoto, A. R. V. R., Hsu, F. C., Jackson, A. U., Kammerer, C. M., Kasturiratne, A., Komulainen, P., Kühnel, B., Leander, K., Lee, W. J., Lin, K. H., Luan, J., Lyytikäinen, L. P., McKenzie, C. A., Nelson, C. P., Noordam, R., Scott, R. A., Sheu, W. H. H., Stančáková, A., Takeuchi, F., Van Der Most, P. J., Varga, T. V., Waken, R. J., Wang, H., Wang, Y., Ware, E. B., Weiss, S., Wen, W., Yanek, L. R., Zhang, W., Zhao, J. H., Afaq, S., Alfred, T., Amin, N., Arking, D. E., Aung, T., Barr, R. G., Bielak, L. F., Boerwinkle, E., Bottinger, E. P., Braund, P. S., Brody, J. A., Broeckel, U., Cade, B., Campbell, A., Canouil, M., Chakravarti, A., Cocca, M., Collins, F. S., Connell, J. M., De Mutsert, R., De Silva, H. J., Dörr, M., Duan, Q., Eaton, C. B., Ehret, G., Evangelou, E., Faul, J. D., Forouhi, N. G., Franco, O. H., Friedlander, Y., Gao, H., Gigante, B., Gu, C. C., Gupta, P., Hagenaars, S. P., Harris, T. B., He, J., Heikkinen, S., Heng, C. K., Hofman, A., Howard, B. V., Hunt, S. C., Irvin, M. R., Jia, Y., Katsuya, T., Kaufman, J., Kerrison, N. D., Khor, C. C., Koh, W. P., Koistinen, H. A., Kooperberg, C. B., Krieger, J. E., Kubo, M., Kutalik, Z., Kuusisto, J., Lakka, T. A., Langefeld, C. D., Langenberg, C., Launer, L. J., Lee, J. H., Lehne, B., Levy, D., Lewis, C. E., Li, Y., Lim, S. H., Liu, C. T., Liu, J., Liu, J., Liu, Y., Loh, M., Lohman, K. K., Louie, T., Mägi, R., Matsuda, K., Meitinger, T., Metspalu, A., Milani, L., Momozawa, Y., Thomas, T. H., Nalls, M. A., Nasri, U., O'Connell, J. R., Ogunniyi, A., Palmas, W. R., Palmer, N. D., Pankow, J. S., Pedersen, N. L., Peters, A., Peyser, P. A., Polasek, O., Porteous, D., Raitakari, O. T., Renström, F., Rice, T. K., Ridker, P. M., Robino, A., Robinson, J. G., Rose, L. M., Rudan, I., Sabanayagam, C., Salako, B. L., Sandow, K., Schmidt, C. O., Schreiner, P. J., Scott, W. R., Sever, P., Sims, M., Sitlani, C. M., Smith, B. H., Smith, J. A., Snieder, H., Starr, J. M., Strauch, K., Tang, H., Taylor, K. D., Teo, Y. Y., Tham, Y. C., Uitterlinden, A. G., Waldenberger, M., Wang, L., Wang, Y. X., Wei, W. B., Wilson, G., Wojczynski, M. K., Xiang, Y. B., Yao, J., Yuan, J. M., Zonderman, A. B., Becker, D. M., Boehnke, M., Bowden, D. W., Chambers, J. C., Chen, Y. D. I., Weir, D. R., De Faire, U., Deary, I. J., Esko, T., Farrall, M., Forrester, T., Freedman, B. I., Froguel, P., Gasparini, P., Gieger, C., Horta, B. L., Hung, Y. J., Jonas, J. B., Kato, N., Kooner, J. S., Laakso, M., Lehtimäki, T., Liang, K. W., Magnusson, P. K. E., Oldehinkel, A. J., Pereira, A. C., Perls, T., Rauramaa, R., Redline, S., Rettig, R., Samani, N. J., Scott, J., Shu, X. O., Van Der Harst, P., Wagenknecht, L. E., Wareham, N. J., Watkins, H., Wickremasinghe, A. R., Wu, T., Kamatani, Y., Laurie, C. C., Bouchard, C., Cooper, R. S., Evans, M. K., Gudnason, V., Hixson, J., Kardia, S. L. R., Kritchevsky, S. B., Psaty, B. M., Van Dam, R. M., Arnett, D. K., Mook-Kanamori, D. O., Fornage, M., Fox, E. R., Hayward, C., Van Duijn, C. M., Tai, E. S., Wong, T. Y., Loos, R. J. F., Reiner, A. P., Rotimi, C. N., Bierut, L. J., Zhu, X., Cupples, L. A., Province, M. A., Rotter, J. I., Franks, P. W., Rice, K., Elliott, P., Caulfield, M. J., Gauderman, W. J., Munroe, P. B., Rao, D. C. & Morrison, A. C., Aug 1 2019, In: Human molecular genetics. 28, 15, p. 2615-2633 19 p.

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    24 Scopus citations
  • An exome-wide sequencing study of the GOLDN cohort reveals novel associations of coding variants and fasting plasma lipids

    Geng, X., Irvin, M. R., Hidalgo, B., Aslibekyan, S., Srinivasasainagendra, V., An, P., Frazier-Wood, A. C., Tiwari, H. K., Dave, T., Ryan, K., Ordovas, J. M., Straka, R. J., Feitosa, M. F., Hopkins, P. N., Borecki, I., Province, M. A., Mitchell, B. D., Arnett, D. K. & Zhi, D., 2019, In: Frontiers in Genetics. 10, feburay, 158.

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    2 Scopus citations