Personal profile
Research interests
The research in the Diamond laboratory focuses on the interface between viral pathogenesis and the host immune response. For several years, we have been primarily focused on two globally important mosquito-borne human pathogens West Nile virus and Dengue virus. Both are single-stranded positive-sense RNA viruses of the same genus (Flavivirus) that cause human disease worldwide. Recently, we have begun to study another member of the same virus family, hepatitis C, which causes chronic hepatitis, cirrhosis, and hepatocellular carcinoma. Investigations with hepatitis C virus are aimed at generating a novel mouse model and understanding the epitope specificity of protective antibodies against this virus.
Clinical interests
West Nile virus, Dengue virus, Chikungunya virus, antibody immunity, interferon immunity
Keywords
- COVID-19
Available to Mentor:
- PhD Students
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Collaborations and top research areas from the last five years
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Adjuvant-free biopolymer particles mimicking the Chikungunya virus surface induce protective immunity
Sivakumaran, N., Freitas, J., Chen, S., Lam, A. K., Adams, L. J., Diamond, M. S., Mahalingam, S. & Rehm, B. H. A., Jul 2026, In: Biomaterials. 330, 124000.Research output: Contribution to journal › Article › peer-review
Open Access -
An intranasal adenoviral-vectored vaccine protects against highly pathogenic avian influenza H5N1 in naive and antigen-experienced animals
Ying, B., Pyles, K., Darling, T. L., Seehra, K., Pham, T., Huang, L. C., Harastani, H. H., Sharma, A., Desai, P., Kashentseva, E. A., Curiel, D. T., Peters, B., Case, J. B., Strauch, E. M., Diamond, M. S. & Boon, A. C. M., Feb 17 2026, In: Cell Reports Medicine. 7, 2, 102582.Research output: Contribution to journal › Article › peer-review
Open Access -
Identification of immunodominant T cell epitopes in SARS-CoV-2 spike protein in Syrian hamsters
Soudani, N., Sidney, J., Da Silva Antunes, R., Case, B., Sharma, R., Brew, I., Diamond, M., Dilorenzo, T. P., Ellebedy, A. H., Sette, A. & Boon, A. C. M., Feb 9 2026, In: Journal of immunology (Baltimore, Md. : 1950). 215, 2Research output: Contribution to journal › Article › peer-review
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Long-acting interleukin-7 improves the efficacy of oncolytic viral therapy in glioblastoma
Li, Y. D., Giles, D. A., Huang, Y., Kesarwani, A., Hu, T., Page, L., de Andrade Costa, A., Luo, J., Wolfarth, A., Choi, D., Dang, M. T., Kim, A. H., DiPersio, J. F., Curiel, D. T., Diamond, M. S. & Chheda, M. G., Dec 2026, In: Nature communications. 17, 1, 2893.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
Macrophage–glia interactions regulate immune damage to enteric neurons during West Nile virus infection
Janova, H., Zhao, F. R., Akgul, A., Schatz, M., Alligood, D. M., Alvarado, D. M., Thackray, L. B., Stappenbeck, T. S. & Diamond, M. S., Mar 17 2026, In: Proceedings of the National Academy of Sciences of the United States of America. 123, 11, e2537058123.Research output: Contribution to journal › Article › peer-review
Open Access