Research output per year
Research output per year
Personal profile
Research interests
The lab is interested in the interaction of pathogenic bacteria with their hosts, with an emphasis on the pathogenesis of infections caused by Gram-positive bacteria. Using Streptococcus pyogenes as a model pathogen, the lab investigates the signal transduction mechanisms used by the bacterium to modulate transcriptome behavior in response to tissue-specific nutrional cues. Also of interest are the pathways for protein secretion that the streptococcus uses to target its various protein toxins to specific host cell compartments during infection.
Available to Mentor:
- PhD/MSTP Students
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Collaborations and top research areas from the last five years
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Fibrinolytic-deficiencies predispose hosts to septicemia from a catheter-associated UTI
Molina, J. J., Kohler, K. N., Gager, C., Andersen, M. J., Wongso, E., Lucas, E. R., Paik, A., Xu, W., Donahue, D. L., Bergeron, K., Klim, A., Caparon, M. G., Hultgren, S. J., Desai, A., Ploplis, V. A., Flick, M. J., Castellino, F. J. & Flores-Mireles, A. L., Dec 2024, In: Nature communications. 15, 1, 2704.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Microbial co-occurrences on catheters from long-term catheterized patients
Nye, T. M., Zou, Z., Obernuefemann, C. L. P., Pinkner, J. S., Lowry, E., Kleinschmidt, K., Bergeron, K., Klim, A., Dodson, K. W., Flores-Mireles, A. L., Walker, J. N., Wong, D. G., Desai, A., Caparon, M. G. & Hultgren, S. J., Dec 2024, In: Nature communications. 15, 1, 61.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Central carbon flux controls growth/damage balance for Streptococcus pyogenes
Merriman, J. A., Xu, W. & Caparon, M. G., Jun 2023, In: PLoS pathogens. 19, 6, e1011481.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Volatile profilingdistinguishes Streptococcus pyogenes from other respiratory streptococcal species
Berna, A. Z., Merriman, J. A., Mellett, L., Parchment, D. K., Caparon, M. G. & John, A. R. O., 2023, In: mSphere. 8, 5Research output: Contribution to journal › Article › peer-review
Open Access -
Complete Genome Sequence of the Uropathogenic Methicillin-Resistant Staphylococcus aureus Strain MRSA-1369
Tükenmez, H., Nye, T. M., Bonde, M., Caparon, M. G., Almqvist, F., Hultgren, S. J. & Johansson, J., Oct 2022, In: Microbiology Resource Announcements. 11, 10Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations