• 8182 Citations
1987 …2019

Research output per year

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Personal profile

Research interests

The lab is interested in the interaction of pathogenic bacteria with their hosts, with an emphasis on the pathogenesis of infections caused by Gram-positive bacteria. Using Streptococcus pyogenes as a model pathogen, the lab investigates the signal transduction mechanisms used by the bacterium to modulate transcriptome behavior in response to tissue-specific nutrional cues. Also of interest are the pathways for protein secretion that the streptococcus uses to target its various protein toxins to specific host cell compartments during infection.

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Research Output

Genetics of group A streptococci

Cho, K. H., Port, G. C. & Caparon, M., Mar 1 2019, In : Microbiology spectrum. 7, 2, GPP3-0056-2018.

Research output: Contribution to journalArticle

  • Glutathione synthesis contributes to virulence of streptococcus agalactiae in a murine model of sepsis

    Walker, E. A., Port, G. C., Caparon, M. G. & Janowiak, B. E., Jan 1 2019, In : Journal of bacteriology. 201, 20, e00367-19.

    Research output: Contribution to journalArticle

  • High-resolution imaging reveals microbial biofilms on patient urinary catheters despite antibiotic administration

    Walker, J. N., Flores-Mireles, A. L., Lynch, A. J. L., Pinkner, C., Caparon, M. G., Hultgren, S. J. & Desai, A., Jan 1 2019, (Accepted/In press) In : World Journal of Urology.

    Research output: Contribution to journalArticle

  • Mucosal infection rewires TNFα signaling dynamics to skew susceptibility to recurrence

    Yu, L., O’Brien, V. P., Livny, J., Dorsey, D., Bandyopadhyay, N., Colonna, M., Caparon, M. G., Roberson, E. D. O., Hultgren, S. J. & Hannan, T. J., Aug 2019, In : eLife. 8, e46677.

    Research output: Contribution to journalArticle

    Open Access
  • 6 Scopus citations

    CcpA Coordinates Growth/Damage Balance for Streptococcus pyogenes Pathogenesis

    Paluscio, E., Watson, M. E. & Caparon, M. G., Dec 1 2018, In : Scientific reports. 8, 1, 14254.

    Research output: Contribution to journalArticle

    Open Access
  • 2 Scopus citations