Michael Barratt

2024

A human gut Faecalibacterium prausnitzii fatty acid amide hydrolase

Cheng, J., Venkatesh, S., Ke, K., Barratt, M. J. & Gordon, J., Oct 25 2024, In: Journal of Bio-X Research. 386, 6720, eado6828.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

A microbiome-directed therapeutic food for children recovering from severe acute malnutrition

Hartman, S. J., Hibberd, M. C., Mostafa, I., Naila, N. N., Islam, M. M., Zaman, M. U., Huq, S., Mahfuz, M., Islam, M. T., Mukherji, K., Moghaddam, V. A., Chen, R. Y., Province, M. A., Webber, D. M., Henrissat, S., Henrissat, B., Terrapon, N., Rodionov, D. A., Osterman, A. L. & Barratt, M. J. & 2 others, Ahmed, T. & Gordon, J. I., Oct 2 2024, In: Science translational medicine. 16, 767, eadn2366.

Research output: Contribution to journal › Article › peer-review

Open Access

A microbiota-directed complementary food intervention in 12–18-month-old Bangladeshi children improves linear growth

Mostafa, I., Hibberd, M. C., Hartman, S. J., Hafizur Rahman, M. H., Mahfuz, M., Hasan, S. M. T., Ashorn, P., Barratt, M. J., Ahmed, T. & Gordon, J. I., Jun 2024, In: EBioMedicine. 104, 105166.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

A multi-glycomic platform for the analysis of food carbohydrates

Couture, G., Cheang, S. E., Suarez, C., Chen, Y., Bacalzo, N. P., Jiang, J., Weng, C. Y. C., Stacy, A., Castillo, J. J., Delannoy-Bruno, O., Webber, D. M., Barratt, M. J., Gordon, J. I., Mills, D. A., German, J. B., Fukagawa, N. K. & Lebrilla, C. B., Nov 2024, In: Nature Protocols. 19, 11, p. 3321-3359 39 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

A shared group of bacterial taxa in the duodenal microbiota of undernourished Pakistani children with environmental enteric dysfunction

Iqbal, N. T., Chen, R. Y., Griffin, N. W., Hibberd, M. C., Khalid, A., Sadiq, K., Jamil, Z., Ahmed, K., Iqbal, J., Hotwani, A., Kabir, F., Rahman, N., Rizvi, A., Idress, R., Ahmed, Z., Ahmed, S., Umrani, F., Syed, S., Moore, S. R. & Ali, A. & 2 others, Barratt, M. J. & Gordon, J. I., Jun 2024, In: mSphere. 9, 6

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Bioactive glycans in a microbiome-directed food for children with malnutrition

Hibberd, M. C., Webber, D. M., Rodionov, D. A., Henrissat, S., Chen, R. Y., Zhou, C., Lynn, H. M., Wang, Y., Chang, H. W., Lee, E. M., Lelwala-Guruge, J., Kazanov, M. D., Arzamasov, A. A., Leyn, S. A., Lombard, V., Terrapon, N., Henrissat, B., Castillo, J. J., Couture, G. & Bacalzo, N. P. & 9 others, Chen, Y., Lebrilla, C. B., Mostafa, I., Das, S., Mahfuz, M., Barratt, M. J., Osterman, A. L., Ahmed, T. & Gordon, J. I., Jan 4 2024, In: Nature. 625, 7993, p. 157-165 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

17 Scopus citations

Development and Acceptability of Shelf-Stable Microbiota Directed Complementary Food Formulations

Mostafa, I., Lamiya, U. H., Rasul, M. G., Naila, N. N., Fahim, S. M., Hasan, S. M. T., Barratt, M. J., Gordon, J. I. & Ahmed, T., Jun 1 2024, In: Food and nutrition bulletin. 45, 2-3, p. 67-73 7 p.

Research output: Contribution to journal › Article › peer-review

Prevotella copri and microbiota members mediate the beneficial effects of a therapeutic food for malnutrition

Chang, H. W., Lee, E. M., Wang, Y., Zhou, C., Pruss, K. M., Henrissat, S., Chen, R. Y., Kao, C., Hibberd, M. C., Lynn, H. M., Webber, D. M., Crane, M., Cheng, J., Rodionov, D. A., Arzamasov, A. A., Castillo, J. J., Couture, G., Chen, Y., Balcazo, N. P. & Lebrilla, C. B. & 12 others, Terrapon, N., Henrissat, B., Ilkayeva, O., Muehlbauer, M. J., Newgard, C. B., Mostafa, I., Das, S., Mahfuz, M., Osterman, A. L., Barratt, M. J., Ahmed, T. & Gordon, J. I., Apr 2024, In: Nature microbiology. 9, 4, p. 922-937 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

2022

An approach for evaluating the effects of dietary fiber polysaccharides on the human gut microbiome and plasma proteome

Delannoy-Bruno, O., Desai, C., Castillo, J. J., Couture, G., Barve, R. A., Lombard, V., Henrissat, B., Cheng, J., Han, N., Hayashi, D. K., Meynier, A., Vinoy, S., Lebrilla, C. B., Marion, S., Heath, A. C., Barratt, M. J. & Gordon, J. I., May 17 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 20, e2123411119.

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

Bifidobacterium infantis treatment promotes weight gain in Bangladeshi infants with severe acute malnutrition

Barratt, M. J., Nuzhat, S., Ahsan, K., Frese, S. A., Arzamasov, A. A., Sarker, S. A., Munirul Islam, M., Palit, P., Islam, M. R., Hibberd, M. C., Nakshatri, S., Cowardin, C. A., Guruge, J. L., Byrne, A. E., Venkatesh, S., Sundaresan, V., Henrick, B., Duar, R. M., Mitchell, R. D. & Casaburi, G. & 8 others, Prambs, J., Flannery, R., Mahfuz, M., Rodionov, D. A., Osterman, A. L., Kyle, D., Ahmed, T. & Gordon, J. I., Apr 13 2022, In: Science translational medicine. 14, 640, eabk1107.

Research output: Contribution to journal › Article › peer-review

Open Access

76 Scopus citations

Developing shelf-stable Microbiota Directed Complementary Food (MDCF) prototypes for malnourished children: study protocol for a randomized, single-blinded, clinical study

Mostafa, I., Fahim, S. M., Das, S., Gazi, M. A., Hasan, M. M., Saqeeb, K. N., Mahfuz, M., Lynn, H. B., Barratt, M. J., Gordon, J. I. & Ahmed, T., Dec 2022, In: BMC Pediatrics. 22, 1, 385.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Human Milk Oligosaccharide Compositions Illustrate Global Variations in Early Nutrition

Vinjamuri, A., Davis, J. C. C., Totten, S. M., Wu, L. D., Klein, L. D., Martin, M., Quinn, E. A., Scelza, B., Breakey, A., Gurven, M., Jasienska, G., Kaplan, H., Valeggia, C., Hinde, K., Smilowitz, J. T., Bernstein, R. M., Zivkovic, A. M., Barratt, M. J., Gordon, J. I. & Underwood, M. A. & 3 others, Mills, D. A., German, J. B. & Lebrilla, C. B., May 1 2022, In: Journal of Nutrition. 152, 5, p. 1239-1253 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

25 Scopus citations

Microbial liberation of N-methylserotonin from orange fiber in gnotobiotic mice and humans

Han, N. D., Cheng, J., Delannoy-Bruno, O., Webber, D., Terrapon, N., Henrissat, B., Rodionov, D. A., Arzamasov, A. A., Osterman, A. L., Hayashi, D. K., Meynier, A., Vinoy, S., Desai, C., Marion, S., Barratt, M. J., Heath, A. C. & Gordon, J. I., Jul 7 2022, In: Cell. 185, 14, p. 2495-2509.e11

Research output: Contribution to journal › Article › peer-review

Open Access

42 Scopus citations

Products of gut microbial Toll/interleukin-1 receptor domain NADase activities in gnotobiotic mice and Bangladeshi children with malnutrition

Weagley, J. S., Zaydman, M., Venkatesh, S., Sasaki, Y., Damaraju, N., Yenkin, A., Buchser, W., Rodionov, D. A., Osterman, A., Ahmed, T., Barratt, M. J., DiAntonio, A., Milbrandt, J. & Gordon, J. I., Apr 26 2022, In: Cell Reports. 39, 4, 110738.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

2021

Evaluating microbiome-directed fibre snacks in gnotobiotic mice and humans

Delannoy-Bruno, O., Desai, C., Raman, A. S., Chen, R. Y., Hibberd, M. C., Cheng, J., Han, N., Castillo, J. J., Couture, G., Lebrilla, C. B., Barve, R. A., Lombard, V., Henrissat, B., Leyn, S. A., Rodionov, D. A., Osterman, A. L., Hayashi, D. K., Meynier, A., Vinoy, S. & Kirbach, K. & 5 others, Wilmot, T., Heath, A. C., Klein, S., Barratt, M. J. & Gordon, J. I., Jul 1 2021, In: Nature. 595, 7865, p. 91-95 5 p.

Research output: Contribution to journal › Article › peer-review

83 Scopus citations

Gut microbiome contributions to altered metabolism in a pig model of undernutrition

Chang, H. W., McNulty, N. P., Hibberd, M. C., O’Donnell, D., Cheng, J., Lombard, V., Henrissat, B., Ilkayeva, O., Muehlbauer, M. J., Newgard, C. B., Barratt, M. J., Lin, X., Odle, J. & Gordon, J. I., May 25 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 21, e2024446118.

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

2020

Combined Prebiotic and Microbial Intervention Improves Oral Cholera Vaccination Responses in a Mouse Model of Childhood Undernutrition

Di Luccia, B., Ahern, P. P., Griffin, N. W., Cheng, J., Guruge, J. L., Byrne, A. E., Rodionov, D. A., Leyn, S. A., Osterman, A. L., Ahmed, T., Colonna, M., Barratt, M. J., Delahaye, N. F. & Gordon, J. I., Jun 10 2020, In: Cell Host and Microbe. 27, 6, p. 899-908.e5

Research output: Contribution to journal › Article › peer-review

Open Access

36 Scopus citations

Diarrhea as a potential cause and consequence of reduced gut microbial diversity among undernourished children in peru

Rouhani, S., Griffin, N. W., Yori, P. P., Gehrig, J. L., Olortegui, M. P., Salas, M. S., Trigoso, D. R., Moulton, L. H., Houpt, E. R., Barratt, M. J., Kosek, M. N. & Gordon, J. I., Aug 15 2020, In: Clinical Infectious Diseases. 71, 4, p. 989-999 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

36 Scopus citations

Duodenal microbiota in stunted undernourished children with enteropathy

Chen, R. Y., Kung, V. L., Das, S., Hossain, M. S., Hibberd, M. C., Guruge, J., Mahfuz, M., Begum, K. N., Rahman, M. M., Fahim, S. M., Gazi, M. A., Haque, R., Sarker, S. A., Mazumder, R. N., Di Luccia, B., Ahsan, K., Kennedy, E., Santiago-Borges, J., Rodionov, D. A. & Leyn, S. A. & 4 others, Osterman, A. L., Barratt, M. J., Ahmed, T. & Gordon, J. I., Jul 23 2020, In: New England Journal of Medicine. 383, 4, p. 321-333 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

116 Scopus citations

Gut microbiota features associated with campylobacter burden and postnatal linear growth deficits in a peruvian birth cohort

Rouhani, S., Griffin, N. W., Yori, P. P., Olortegui, M. P., Salas, M. S., Trigoso, D. R., Moulton, L. H., Houpt, E. R., Barratt, M. J., Kosek, M. N. & Gordon, J. I., Aug 15 2020, In: Clinical Infectious Diseases. 71, 4, p. 1000-1007 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

29 Scopus citations

Proof-of-concept study of the efficacy of a microbiota-directed complementary food formulation (MDCF) for treating moderate acute malnutrition

Mostafa, I., Nahar, N. N., Islam, M. M., Huq, S., Mustafa, M., Barratt, M., Gordon, J. I. & Ahmed, T., Feb 17 2020, In: BMC Public Health. 20, 1, 242.

Research output: Contribution to journal › Article › peer-review

Open Access

26 Scopus citations

2019

A sparse covarying unit that describes healthy and impaired human gut microbiota development

Raman, A. S., Gehrig, J. L., Venkatesh, S., Chang, H. W., Hibberd, M. C., Subramanian, S., Kang, G., Bessong, P. O., Lima, A. A. M., Kosek, M. N., Petri, W. A., Rodionov, D. A., Arzamasov, A. A., Leyn, S. A., Osterman, A. L., Huq, S., Mostafa, I., Islam, M., Mahfuz, M. & Haque, R. & 3 others, Ahmed, T., Barratt, M. J. & Gordon, J. I., 2019, In: Science. 365, 6449, Y.

Research output: Contribution to journal › Article › peer-review

Open Access

142 Scopus citations

Effects of microbiota-directed foods in gnotobiotic animals and undernourished children

Gehrig, J. L., Venkatesh, S., Chang, H. W., Hibberd, M. C., Kung, V. L., Cheng, J., Chen, R. Y., Subramanian, S., Cowardin, C. A., Meier, M. F., O’Donnell, D., Talcott, M., Spears, L. D., Semenkovich, C. F., Henrissat, B., Giannone, R. J., Hettich, R. L., Ilkayeva, O., Muehlbauer, M. & Newgard, C. B. & 17 others, Sawyer, C., Head, R. D., Rodionov, D. A., Arzamasov, A. A., Leyn, S. A., Osterman, A. L., Hossain, M. I., Islam, M., Choudhury, N., Sarker, S. A., Huq, S., Mahmud, I., Mostafa, I., Mahfuz, M., Barratt, M. J., Ahmed, T. & Gordon, J. I., 2019, In: Science. 365, 6449, Y.

Research output: Contribution to journal › Article › peer-review

Open Access

300 Scopus citations

Mechanisms by which sialylated milk oligosaccharides impact bone biology in a gnotobiotic mouse model of infant undernutrition

Cowardin, C. A., Ahern, P. P., Kung, V. L., Hibberd, M. C., Cheng, J., Guruge, J. L., Sundaresan, V., Head, R. D., Barile, D., Mills, D. A., Barratt, M. J., Huq, S., Ahmed, T. & Gordon, J. I., Jun 11 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 24, p. 11988-11996 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

61 Scopus citations

Study of Environmental Enteropathy and Malnutrition (SEEM) in Pakistan: Protocols for biopsy based biomarker discovery and validation

Iqbal, N. T., Syed, S., Sadiq, K., Khan, M. N., Iqbal, J., Ma, J. Z., Umrani, F., Ahmed, S., Maier, E. A., Denson, L. A., Haberman, Y., McNeal, M. M., Setchell, K. D. R., Zhao, X., Qureshi, S., Shen, L., Moskaluk, C. A., Liu, T. C., Yilmaz, O. & Brown, D. E. & 5 others, Barratt, M. J., Kung, V. L., Gordon, J. I., Moore, S. R. & Asad Ali, S., Jul 22 2019, In: BMC Pediatrics. 19, 1, 247.

Research output: Contribution to journal › Article › peer-review

Open Access

25 Scopus citations

2017

Bangladesh Environmental Enteric Dysfunction (BEED) study: Protocol for a community-based intervention study to validate non-invasive biomarkers of environmental enteric dysfunction

Mahfuz, M., Das, S., Mazumder, R. N., Masudur Rahman, M., Haque, R., Bhuiyan, M. M. R., Akhter, H., Sarker, M. S. A., Mondal, D., Muaz, S. S. A., Karim, A. S. M. B., Borowitz, S. M., Moskaluk, C. A., Barratt, M. J., Petri, W. A., Gordon, J. I. & Ahmed, T., Aug 1 2017, In: BMJ Open. 7, 8, e017768.

Research output: Contribution to journal › Article › peer-review

Open Access

50 Scopus citations

The effects of micronutrient deficiencies on bacterial species from the human gut microbiota

Hibberd, M. C., Wu, M., Rodionov, D. A., Li, X., Cheng, J., Griffin, N., Barratt, M. J., Giannone, R. J., Hettich, R. L., Osterman, A. L. & Gordon, J. I., May 17 2017, In: Science translational medicine. 9, 390, 4069.

Research output: Contribution to journal › Article › peer-review

Open Access

171 Scopus citations

2016

Gut bacteria that prevent growth impairments transmitted by microbiota from malnourished children

Blanton, L. V., Charbonneau, M. R., Salih, T., Barratt, M. J., Venkatesh, S., Ilkaveya, O., Subramanian, S., Manary, M. J., Trehan, I., Jorgensen, J. M., Fan, Y. M., Henrissat, B., Leyn, S. A., Rodionov, D. A., Osterman, A. L., Maleta, K. M., Newgard, C. B., Ashorn, P., Dewey, K. G. & Gordon, J. I., Feb 19 2016, In: Science. 351, 6275, aad3311.

Research output: Contribution to journal › Article › peer-review

Open Access

559 Scopus citations

Sialylated Milk Oligosaccharides Promote Microbiota-Dependent Growth in Models of Infant Undernutrition

Charbonneau, M. R., O'Donnell, D., Blanton, L. V., Totten, S. M., Davis, J. C. C., Barratt, M. J., Cheng, J., Guruge, J., Talcott, M., Bain, J. R., Muehlbauer, M. J., Ilkayeva, O., Wu, C., Struckmeyer, T., Barile, D., Mangani, C., Jorgensen, J., Fan, Y. M., Maleta, K. & Dewey, K. G. & 5 others, Ashorn, P., Newgard, C. B., Lebrilla, C., Mills, D. A. & Gordon, J. I., Feb 25 2016, In: Cell. 164, 5, p. 859-871 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

481 Scopus citations

2014

Persistent gut microbiota immaturity in malnourished Bangladeshi children

Subramanian, S., Huq, S., Yatsunenko, T., Haque, R., Mahfuz, M., Alam, M. A., Benezra, A., Destefano, J., Meier, M. F., Muegge, B. D., Barratt, M. J., VanArendonk, L. G., Zhang, Q., Province, M. A., Petri, W. A., Ahmed, T. & Gordon, J. I., 2014, In: Nature. 510, 7505, p. 417-421 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

923 Scopus citations

2010

Evaluation of phenoxybenzamine in the CFA model of pain following gene expression studies and connectivity mapping

Chang, M., Smith, S., Thorpe, A., Barratt, M. J. & Karim, F., Sep 16 2010, In: Molecular Pain. 6, 56.

Research output: Contribution to journal › Article › peer-review

Open Access

58 Scopus citations

2000

Phosphoacetylation of histone H3 on c-fos- and c-jun-associated nucleosomes upon gene activation

Clayton, A. L., Rose, S., Barratt, M. J. & Mahadevan, L. C., Jul 17 2000, In: EMBO Journal. 19, 14, p. 3714-3726 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

366 Scopus citations

1999

The nucleosomal response associated with immediate-early gene induction is mediated via alternative MAP kinase cascades: MSK1 as a potential histone H3/HMG-14 kinase

Thomson, S., Clayton, A. L., Hazzalin, C. A., Rose, S., Barratt, M. J. & Mahadevan, L. C., Sep 1 1999, In: EMBO Journal. 18, 17, p. 4779-4793 15 p.

Research output: Contribution to journal › Article › peer-review

410 Scopus citations

1997

Use of reversed-phase high-performance liquid chromatography on polystyrene-divinylbenzene columns for the rapid separation and purification of acid-soluble nuclear proteins

Zhelev, N. Z., Barratt, M. J. & Mahadevan, L. C., Feb 28 1997, In: Journal of Chromatography A. 763, 1-2, p. 65-70 6 p.

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

1996

p38/RK is essential for stress-induced nuclear responses: JNK/SAPKs and c-Jun/ATF-2 phosphorylation are insufficient

Hazzalin, C. A., Cano, E., Cuenda, A., Barratt, M. J., Cohen, P. & Mahadevan, L. C., 1996, In: Current Biology. 6, 8, p. 1028-1031 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

205 Scopus citations

1994

A mitogen- and anisomycin-stimulated kinase phosphorylates HMG-14 in its basic amino-terminal domain in vivo and on isolated mononucleosomes

Barratt, M. J., Hazzalin, C. A., Zhelev, N. & Mahadevan, L. C., 1994, In: EMBO Journal. 13, 19, p. 4524-4535 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

49 Scopus citations

Mitogen-stimulated phosphorylation of histone H3 is targeted to a small hyperacetylation-sensitive fraction

Barratt, M. J., Hazzalin, C. A., Cano, E. & Mahadevan, L. C., May 24 1994, In: Proceedings of the National Academy of Sciences of the United States of America. 91, 11, p. 4781-4785 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

139 Scopus citations

1993

Signalling to chromatin and the superinduction of proto-oncogenes

Zhelev, N., Kardalinou, E., Hazzalin, C. A., Cano, E., Barratt, M. J. & Mahadevan, L. C., 1993, In: Biochemical Society transactions. 21, 4, p. 907-911 5 p.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

1991

Rapid histone H3 phosphorylation in response to growth factors, phorbol esters, okadaic acid, and protein synthesis inhibitors

Mahadevan, L. C., Willis, A. C. & Barratt, M. J., May 31 1991, In: Cell. 65, 5, p. 775-783 9 p.

Research output: Contribution to journal › Article › peer-review

402 Scopus citations

Michael Barratt

Research output

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