Maxene Ilagan

Associate Professor of Biochemistry and Molecular Biophysics, Associate Professor of Developmental Biology

    • 3485 Citations
    19962020

    Research output per year

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    Personal profile

    Research interests

    The High Throughput Screening Center (HTSC) provides screening services to enable investigators to identify new compounds and cellular activities that modify their biology of interest for the purposes of basic research, target identification and validation, and/or therapeutic drug discovery.

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    Research Output

    Neutralizing Antibody and Soluble ACE2 Inhibition of a Replication-Competent VSV-SARS-CoV-2 and a Clinical Isolate of SARS-CoV-2

    Case, J. B., Rothlauf, P. W., Chen, R. E., Liu, Z., Zhao, H., Kim, A. S., Bloyet, L. M., Zeng, Q., Tahan, S., Droit, L., Ilagan, M. X. G., Tartell, M. A., Amarasinghe, G., Henderson, J. P., Miersch, S., Ustav, M., Sidhu, S., Virgin, H. W., Wang, D., Ding, S. & 5 others, Corti, D., Theel, E. S., Fremont, D. H., Diamond, M. S. & Whelan, S. P. J., Sep 9 2020, In : Cell Host and Microbe. 28, 3, p. 475-485.e5

    Research output: Contribution to journalArticle

    Open Access
  • 7 Scopus citations

    Identification of druggable small molecule antagonists of the Plasmodium falciparum hexose transporter PfHT and assessment of ligand access to the glucose permeation pathway via FLAG-mediated protein engineering

    Heitmeier, M. R., Hresko, R. C., Edwards, R. L., Prinsen, M. J., Ilagan, M. X. G., Odom John, A. R. & Hruz, P. W., May 2019, In : PloS one. 14, 5, e0216457.

    Research output: Contribution to journalArticle

    Open Access
  • 1 Scopus citations

    The aminoalkylindole bml-190 negatively regulates chitosan synthesis via the cyclic amp/protein kinase a1 pathway in cryptococcus neoformans

    Maybruck, B. T., Lam, W. C., Specht, C. A., Ilagan, M. X. G., Donlin, M. J. & Lodge, J. K., Nov 1 2019, In : mBio. 10, 6, e02264-19.

    Research output: Contribution to journalArticle

    Open Access
  • A Sensitive in Vitro High-Throughput Screen to Identify Pan-filoviral Replication Inhibitors Targeting the VP35-NP Interface

    Liu, G., Nash, P. J., Johnson, B., Pietzsch, C., Ilagan, M. X. G., Bukreyev, A., Basler, C. F., Bowlin, T. L., Moir, D. T., Leung, D. W. & Amarasinghe, G. K., Mar 10 2017, In : ACS Infectious Diseases. 3, 3, p. 190-198 9 p.

    Research output: Contribution to journalArticle

  • 10 Scopus citations

    A novel fluorescence resonance energy transfer-based screen in high-throughput format to identify inhibitors of malarial and human glucose transporters

    Kraft, T. E., Heitmeier, M. R., Putanko, M., Edwards, R. L., Ilagan, M. X. G., Payne, M. A., Autry, J. M., Thomas, D. D., Odom, A. R. & Hruz, P. W., Dec 2016, In : Antimicrobial agents and chemotherapy. 60, 12, p. 7407-7414 8 p.

    Research output: Contribution to journalArticle

    Open Access
  • 7 Scopus citations