Research output per year
Research output per year
Personal profile
Research interests
The Silva lab studies bone. We are focused on two main questions. 1) How does mechanical loading (e.g., weight-bearing exercise) stimulate bone formation and increase bone mass? 2) How do bones heal after injury (e.g., stress fracture and full fracture)? By studying how the skeleton responds to mechanical stimulation and how it heals after injury, we aim to contribute to the discovery of new approaches to treat reduced bone mass and strength in aging/osteoporosis, and to enhance bone repair in patients who suffer from non-healing fractures.
Available to Mentor:
- PhD/MSTP Students
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Collaborations and top research areas from the last five years
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Cyclic testing of six-strand suture techniques for zone 2 flexor tendon lacerations
Kusano, N., Zaegel, M. A. & Silva, M. J., Sep 2024, In: Journal of Orthopaedic Science. 29, 5, p. 1214-1219 6 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Multi-organ phenotypes in mice lacking latent TGFβ binding protein 2 (LTBP2)
Bodmer, N. K., Knutsen, R. H., Roth, R. A., Castile, R. M., Brodt, M. D., Gierasch, C. M., Broekelmann, T. J., Gibson, M. A., Haspel, J. A., Lake, S. P., Koenitzer, J. R., Brody, S. L., Silva, M. J., Mecham, R. & Ornitz, D. M., Feb 2024, In: Developmental Dynamics. 253, 2, p. 233-254 22 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Multi-scale cortical bone traits vary in females and males from two mouse models of genetic diversity
Migotsky, N., Kumar, S., Shuster, J. T., Coulombe, J. C., Senwar, B., Gestos, A. A., Farber, C. R., Ferguson, V. L. & Silva, M. J., May 2024, In: JBMR Plus. 8, 5Research output: Contribution to journal › Article › peer-review
Open Access -
Postnatal Osterix but not DMP1 lineage cells significantly contribute to intramembranous ossification in three preclinical models of bone injury
Buettmann, E. G., Yoneda, S., Hu, P., McKenzie, J. A. & Silva, M. J., Jan 4 2023, In: Frontiers in Physiology. 13, 1083301.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
T cells heal bone fractures with help from the gut microbiome
Aurora, R. & Silva, M. J., Apr 17 2023, In: Journal of Clinical Investigation. 133, 8, e167311.Research output: Contribution to journal › Review article › peer-review
Open Access5 Scopus citations