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Personal profile

Research interests

Along with colleagues we have used clinical databases and laboratory modeling to study the general fields of intestinal inflammation, injury repair and carcinogenesis. Our work is inspired by clinical interactions with patients affected by the human inflammatory bowel diseases and those patients who experience significant gastrointestinal side effects from radiotherapy induced bowel injury. The overarching goal of our research is to identify novel ways to improve life for patients enduring these illnesses. Translating our findings to human relevance is aided by our Division’s DDRCC clinical database and tissue repository.

Areas of Clinical Interest

Gastroenterology, inflammatory bowel disease, Crohn's disease

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Research Output

Dynamic immunoglobulin responses to gut bacteria during inflammatory bowel disease

Rengarajan, S., Vivio, E. E., Parkes, M., Peterson, D. A., Roberson, E. D. O., Newberry, R. D., Ciorba, M. A. & Hsieh, C. S., May 3 2020, In : Gut microbes. 11, 3, p. 405-420 16 p.

Research output: Contribution to journalArticle

  • 4 Scopus citations
  • Impact of Bariatric Surgery on the Long-term Disease Course of Inflammatory Bowel Disease

    Braga Neto, M. B., Gregory, M. H., Ramos, G. P., Bazerbachi, F., Bruining, D. H., Abu Dayyeh, B. K., Kushnir, V. M., Raffals, L. E., Ciorba, M., Loftus, E. V. & Deepak, P., Jun 18 2020, In : Inflammatory bowel diseases. 26, 7, p. 1089-1097 9 p.

    Research output: Contribution to journalArticle

  • 1 Scopus citations

    Interferon-Induced IDO1 Mediates Radiation Resistance and Is a Therapeutic Target in Colorectal Cancer

    Chen, B., Alvarado, D. M., Iticovici, M., Kau, N. S., Park, H., Parikh, P. J., Thotala, D. & Ciorba, M. A., Apr 1 2020, In : Cancer immunology research. 8, 4, p. 451-464 14 p.

    Research output: Contribution to journalArticle

  • 1 Scopus citations

    Patient-derived small intestinal myofibroblasts direct perfused, physiologically responsive capillary development in a microfluidic Gut-on-a-Chip Model

    Seiler, K. M., Bajinting, A., Alvarado, D. M., Traore, M. A., Binkley, M. M., Goo, W. H., Lanik, W. E., Ou, J., Ismail, U., Iticovici, M., King, C. R., VanDussen, K. L., Swietlicki, E., Gazit, V., Guo, J., Luke, C. J., Stappenbeck, T., Ciorba, M. A., George, S. C., Meacham, J. M. & 3 others, Rubin, D. C., Good, M. & Warner, B. W., Dec 1 2020, In : Scientific reports. 10, 1, 3842.

    Research output: Contribution to journalArticle

    Open Access
  • 2 Scopus citations