Research Output per year
Research Output per year
Personal profile
Research interests
My laboratory studies the pathogenic mechanisms leading to the clinical signs associated with lysosomal storage diseases. We also develop effective therapeutic approaches for this class of inherited pediatric disease. Specifically, we have developed recombinant enzyme replacement, stem cell-mediated and gene transfer therapies in our mouse models of disease.
Fingerprint
Dive into the research topics where Mark Sands is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 9 Similar Profiles
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Research Output
-
Cell-autonomous expression of the acid hydrolase galactocerebrosidase
Mikulka, C. R., Dearborn, J. T., Benitez, B. A., Strickland, A., Liu, L., Milbrandt, J. & Sands, M. S., Apr 21 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 16, p. 9032-9041 10 p.Research output: Contribution to journal › Article › peer-review
-
Comparative proteomic profiling reveals mechanisms for early spinal cord vulnerability in CLN1 disease
Nelvagal, H. R., Hurtado, M. L., Eaton, S. L., Kline, R. A., Lamont, D. J., Sands, M. S., Wishart, T. M. & Cooper, J. D., Dec 1 2020, In: Scientific reports. 10, 1, 15157.Research output: Contribution to journal › Article › peer-review
Open Access -
Krabbe disease successfully treated via monotherapy of intrathecal gene therapy
Bradbury, A. M., Bagel, J. H., Nguyen, D., Lykken, E. A., Salvador, J. P., Jiang, X., Swain, G. P., Assenmacher, C. A., Hendricks, I. J., Miyadera, K., Hess, R. S., Ostrager, A., ODonnell, P., Sands, M. S., Ory, D. S., Shelton, G. D., Bongarzone, E. R., Gray, S. J. & Vite, C. H., Sep 1 2020, In: Journal of Clinical Investigation. 130, 9, p. 4906-4920 15 p.Research output: Contribution to journal › Article › peer-review
-
Macrophage secretion of miR-106b-5p causes renin-dependent hypertension
Oh, J., Matkovich, S. J., Riek, A. E., Bindom, S. M., Shao, J. S., Head, R. D., Barve, R. A., Sands, M. S., Carmeliet, G., Osei-Owusu, P., Knutsen, R. H., Zhang, H., Blumer, K. J., Nichols, C. G., Mecham, R. P., Baldán, Benitez, B. A., Sequeira-Lopez, M. L., Gomez, R. A. & Bernal-Mizrachi, C., Dec 1 2020, In: Nature communications. 11, 1, 4798.Research output: Contribution to journal › Article › peer-review
Open Access -
Spinal manifestations of CLN1 disease start during the early postnatal period
Nelvagal, H. R., Dearborn, J. T., Ostergaard, J. R., Sands, M. S. & Cooper, J. D., 2020, (Accepted/In press) In: Neuropathology and Applied Neurobiology.Research output: Contribution to journal › Article › peer-review
Open Access