Personal profile
Research interests
My research interests include development of clinical trials for breast cancer and lymphoma patients. In particular, I have an active interest in studying the risk of cardiac toxicity in patients who have received radiation as part of their breast cancer therapy. The goal of this work is to identify radiation dose constraints which result in very low risk of cardiac toxicity and could be used in designing radiation treatment plans for patients in the future.
Clinical interests
Radiation therapy using all modalities of external beam radiation ( 3-D conformal treatment planning, IMRT, stereotactic body radiotherapy, image guided radiation therapy, accelerated partial breast irradiation, tomotherapy, advanced localization systems, total body radiation, PET and MRI fusion. Also brachytherapy, Gamma Knife radiosurgery
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Collaborations and top research areas from the last five years
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Long-Term Results of a Phase 2 Prospective Clinical Trial of Single-Fraction, High-Gradient Adjuvant Partial Breast Irradiation in Early-Stage, Hormone-Positive Breast Cancer
Lakomy, D. S., Kennedy, W. R., Laugeman, E., Huang, Y., Margenthaler, J. A., Bagegni, N. A., Brunt, L., Thomas, M. & Zoberi, I., Apr 1 2026, In: International Journal of Radiation Oncology Biology Physics. 124, 5, p. 1239-1247 9 p.Research output: Contribution to journal › Article › peer-review
1 Link opens in a new tab Scopus citations -
Impact of a 7-Gene Predictive Biosignature on Adjuvant Radiation Therapy Recommendations in Patients Undergoing Breast-Conserving Surgery for Ductal Carcinoma In Situ
Margenthaler, J. A., Zoberi, I., Thomas, M. & Kennard, K., Apr 1 2025, In: Journal of the American College of Surgeons. 240, 4, p. 670-676 7 p.Research output: Contribution to journal › Article › peer-review
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Long-Term Outcomes of Multimodality Accelerated Partial Breast Irradiation for Ductal Carcinoma In Situ
Raju-Salicki, S., Stowe, H. B., D'Souza, A., Huang, Y., Mahmood, M., Kennedy, W. R., Brenneman, R. J., Margenthaler, J., Glover-Collins, K., Cyr, A., Bergom, C., Yang, J., Thomas, M. A., Zoberi, J. & Zoberi, I., Jul 2025, In: Advances in Radiation Oncology. 10, 7, 101792.Research output: Contribution to journal › Article › peer-review
Open Access -
A quality assurance framework for routine monitoring of deep learning cardiac substructure computed tomography segmentation models in radiotherapy
Jin, X., Hao, Y., Hilliard, J., Zhang, Z., Thomas, M. A., Li, H., Jha, A. K. & Hugo, G. D., Apr 2024, In: Medical physics. 51, 4, p. 2741-2758 18 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Link opens in a new tab Scopus citations -
Heart Sparing Radiotherapy Techniques in Breast Cancer: A Focus on Deep Inspiration Breath Hold
Stowe, H. B., Andruska, N. D., Reynoso, F., Thomas, M. & Bergom, C., 2022, In: Breast Cancer: Targets and Therapy. 14, p. 175-186 12 p.Research output: Contribution to journal › Review article › peer-review
Open Access37 Link opens in a new tab Scopus citations