Marcus Raichle

Professor of Radiology, Professor of Neuroscience, Professor of Neurology, Professor of Psychological & Brain Sciences, Professor of Biomedical Engineering, Alan A and Edith L Wolff Distinguished Professor of Medicine

    • 98421 Citations
    1968 …2020

    Research output per year

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    Personal profile

    Research interests

    Our work uses functional Magnetic Resonance Imaging (fMRI) and Positron Emission Tomography (PET) to study human brain organization and function in health and disease. The research can be divided into two general categories: studies of normal human brain function and studies of the biological origins of functional brain imaging signals obtained with MRI and PET. We use fMRI to determine systems within the normal human brain concerned with specific cognitive and emotional functions. We are also studying patients with psychiatric diseases such as depression and anxiety to determine the system responsible for the disease and the response of these systems to treatment. We use both PET and MRI to relate changes in blood flow and brain metabolism to underlying changes in cellular activity associated with brain function.

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    Research Output

    Amyloid and Tau Pathology Associations With Personality Traits, Neuropsychiatric Symptoms, and Cognitive Lifestyle in the Preclinical Phases of Sporadic and Autosomal Dominant Alzheimer's Disease

    Dominantly Inherited Alzheimer Network (DIAN) & PREVENT-AD Research Group, 2020, (Accepted/In press) In : Biological Psychiatry.

    Research output: Contribution to journalArticle

  • 1 Scopus citations

    A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer’s disease

    the Dominantly Inherited Alzheimer Network, Mar 1 2020, In : Nature medicine. 26, 3, p. 398-407 10 p.

    Research output: Contribution to journalArticle

  • 18 Scopus citations

    A telescope GWAS analysis strategy, based on SNPs-genes-pathways ensamble and on multivariate algorithms, to characterize late onset Alzheimer’s disease

    The Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2020, In : Scientific reports. 10, 1, 12063.

    Research output: Contribution to journalArticle

    Open Access
  • Author Correction: Multimodal hippocampal subfield grading for Alzheimer’s disease classification (Scientific Reports, (2019), 9, 1, (13845), 10.1038/s41598-019-49970-9)

    Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2020, In : Scientific reports. 10, 1, 10969.

    Research output: Contribution to journalComment/debate

    Open Access
  • Challenges and Opportunities with Causal Discovery Algorithms: Application to Alzheimer’s Pathophysiology

    The Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2020, In : Scientific reports. 10, 1, 2975.

    Research output: Contribution to journalArticle

    Open Access
  • 2 Scopus citations