Manu Goyal

Willing to Mentor

Available to Mentor:

PhD Students

3543

Citations

Research activity per year

Research interests

Manu S. Goyal, MD, MSc. is a neuroradiologist in the Mallinckrodt Institute of Radiology, double board-certified in neurology and radiology. His research is similarly integrative as it strives to combine imaging, genomic, and metabolomic approaches to investigations in the human brain. His prior work, with Professor Marcus Raichle, found that aerobic glycolysis, a form of metabolism typical of cancer, is also typical of the brain during childhood. Further, they found that its persistence in certain regions of the adult brain is related to ongoing synaptic plasticity and myelination. Dr. Goyal now plans to develop an integrated omics approach to studying the human brain, and use this to more fully understand brain metabolism in the context of normal function, development, and recovery from brain injury such as stroke.

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Clinical interests

Neuroradiology, stroke, radiology

Information for Patients

Mentoring

Mentorship is a favorite part of my job and I am committed to our students and trainees, according to their goals and needs. Our lab is committed to diversity, equity, and inclusion in all of our activities ranging from research participation to education and employment.

Available to Mentor:

PhD Students

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95 Article
12 Review article
9 Comment/debate
4 Letter
More

Aerobic glycolysis in Schizophrenia: Developmental rescue or energetic breakdown?
Memetoglu, O., Goyal, M. S., Chouinard, V. A., Du, F. & Ongur, D., 2026, (Accepted/In press) In: Molecular Psychiatry.
Research output: Contribution to journal › Review article › peer-review

Open Access
AI-enhanced Centiloid quantification of amyloid PET images
for the Alzheimer's Disease Neuroimaging Initiative, OASIS3, the A4/LEARN Study Team, the AMYPAD consortium, The Health and Aging Brain Study (HABS-HD) Study Team, Mayo Clinic Study of Aging, WRAP, ADNI-DOD, PISA, ADNeT & the AIBL research group, Feb 2026, In: Alzheimer's and Dementia. 22, 2, e71162.
Research output: Contribution to journal › Article › peer-review

Open Access
Brain metabolic-functional (de)coupling from health to glioma dysfunction
Vallini, G., Baron, G., Silvestri, E., Volpi, T., Vlassenko, A. G., Goyal, M. S., Chiuso, A., Cecchin, D., Corbetta, M. & Bertoldo, A., Dec 2026, In: Communications Biology. 9, 1, 5.
Research output: Contribution to journal › Article › peer-review

Open Access
Cortical asymmetry in autosomal dominant Alzheimer’s disease progression
Pérez-Millan, A., Falgàs, N., Bosch, B., Borrego-Écija, S., Antonell, A., Fernández-Villullas, G., Esteller-Gauxax, D., Tort-Merino, A., Bargalló, N., Balasa, M., Lladó, A., Aguillon, D., Chrem, P., Day, G. S., Devenney, E., Huey, E. D., Ikeuchi, T., Jucker, M., Kasuga, K. & Vöglein, J. & 119 others, Roh, J. H., Vitali, P., Sosa Ortiz, A. L., Llibre-Guerra, J. J., Gordon, B. A., McDade, E., Bateman, R. J., Sánchez-Valle, R., McDade, Bateman, R., Daniels, A. J., Courtney, L., Ziegemeier, A., Skrbec, K., Hellm, C., Martin, M., Ziegemeier, E., Bartzel, J., Supnet-Bell, C., Xiong, C., Xu, X., Lu, R., Wang, G., Li, Y., Nie, Y., Gremminger, E., Perrin, R. J., Franklin, E., Ibanez, L., Jerome, G., Stauber, J., Baker, B., Minton, M., Cruchaga, C., Goate, A. M., Renton, A. E., Picarello, D. M., Fulton-Howard, B., Benzinger, T. L. S., Banks, J., Hornbeck, R., Chen, A., Chen, C., Flores, S., Goyal, M., Hobbs, D., Joseph-Mathurin, N., Jackson, K., Keefe, S., Koudelis, D., Massoumzadeh, P., McCullough, A., McKay, N., Nicklaus, J., Pulizos, C., Wang, Q., Sabaredzovic, E., Scott, J., Simmons, A., Rizzo, J., Vlassenko, A., Wang, Y., Hassenstab, J., Smith, J., Stout, S., Aschenbrenner, A. J., Karch, C. M., Marsh, J., Morris, J. C., Holtzman, D. M., Barthélemy, N. R., Xu, J., Berman, S. B., Ikonomovic, S., Graff-Radford, N. R., Farlow, M., Chhatwal, J. P., Maa, C., Ishiguro, T., Ishii, K., Senda, M., Niimi, Y., Salloway, S., Schofield, P. R., Brooks, W. S., Bechara, J. A., Martins, R., Fox, N. C., Cash, D. M., Ryan, N. S., Laske, C., Timofejavaite, R., Kuder-Buletta, E., Graber-Sultan, S., La Fougère, C., Reischl, G., Obermueller, U., Levin, J., Rödenbeck, Y., Lee, J. H., Allegri, R. F., Mendez, P. C., Surace, E., Vazquez, S., Leon, Y. M., Ramirez, L., Serna, L., Baena, A., Bocanegra, Y., Levey, A. I., Johnson, E. C. B., Seyfried, N. T., Ringman, J., Fagan, A. M., Mori, H., Masters, C., Noble, J. M., Sanchez-Valle, R. & Lopera, F., 2026, In: Brain Communications. 8, 1, fcaf488.
Research output: Contribution to journal › Article › peer-review

Open Access
Longitudinal subcortical volume changes and their correlations with multiple PET and fluid biomarkers in dominantly inherited Alzheimer’s disease
Choo, I. H., Park, H., Gordon, B. A., Bateman, R. J., Bateman, R., Daniels, A. J., Courtney, L., Ziegemeier, A., Skrbec, K., Hellm, C., Martin, M., Ziegemeier, E., Bartzel, J., McDade, E., Libre-Guerra, J. J., Supnet-Bell, C., Xiong, C., Xu, X., Lu, R. & Wang, G. & 106 others, Li, Y., Nie, Y., Gremminger, E., Perrin, R. J., Franklin, E., Ibanez, L., Jerome, G., Stauber, J., Baker, B., Minton, M., Cruchaga, C., Goate, A. M., Renton, A. E., Picarello, D. M., Fulton-Howard, B., Benzinger, T. L. S., Gordon, B. A., Banks, J., Hornbeck, R., Chen, A., Chen, C., Flores, S., Goyal, M., Hobbs, D., Joseph-Mathurin, N., Jackson, K., Keefe, S., Koudelis, D., Massoumzadeh, P., McCullough, A., McKay, N., Nicklaus, J., Pulizos, C., Wang, Q., Sabaredzovic, E., Scott, J., Simmons, A., Rizzo, J., Vlassenko, A., Wang, Y., Hassenstab, J., Smith, J., Stout, S., Aschenbrenner, A. J., Karch, C. M., Marsh, J., Morris, J. C., Holzman, D. M., Barthélemy, N. R., Xu, J., Berman, S. B., Ikonomovic, S., Day, G. S., Graff-Radford, N. R., Farlow, M., Chhatwal, J. P., Ikeuchi, T., Kasuga, K., Ishiguro, T., Ishii, K., Senda, M., Niimi, Y., Huey, E. D., Salloway, S., Devenney, E., Schofield, P. R., Brooks, W. S., Bechara, J. A., Martins, R., Fox, N. C., Cash, D. M., Ryan, N. S., Jucker, M., Laske, C., Timofejavaite, R., Kuder-Buletta, E., Graber-Sultan, S., la Fougère, C., Reischl, G., Obermueller, U., Levin, J., Rödenbeck, Y., Vöglein, J., Lee, J. H., Roh, J. H., Vitali, P., Allegri, R. F., Mendez, P. C., Surace, E., Vazquez, S., Aguillon, D., Leon, Y. M., Ramirez, L., Serna, L., Baena, A., Bocanegra, Y., Levey, A. I., Johnson, E. C. B., Seyfried, N. T., Ringman, J., Fagan, A. M., Mori, H., Masters, C., Nobles, J. M., Sanchez-Valle, R. & Lopera, F., Apr 2026, In: Journal of Prevention of Alzheimer's Disease. 13, 4, 100513.
Research output: Contribution to journal › Article › peer-review

Open Access

Manu Goyal

Personal profile

Research interests

Clinical interests

Mentoring

Available to Mentor:

Fingerprint

Collaborations and top research areas from the last five years

Dive into details

Aerobic glycolysis in Schizophrenia: Developmental rescue or energetic breakdown?

AI-enhanced Centiloid quantification of amyloid PET images

Brain metabolic-functional (de)coupling from health to glioma dysfunction

Cortical asymmetry in autosomal dominant Alzheimer’s disease progression

Longitudinal subcortical volume changes and their correlations with multiple PET and fluid biomarkers in dominantly inherited Alzheimer’s disease

Manu Goyal

Personal profile

Research interests

Clinical interests

Mentoring

Available to Mentor:

Fingerprint

Collaborations and top research areas from the last five years

Research output

Aerobic glycolysis in Schizophrenia: Developmental rescue or energetic breakdown?

AI-enhanced Centiloid quantification of amyloid PET images

Brain metabolic-functional (de)coupling from health to glioma dysfunction

Cortical asymmetry in autosomal dominant Alzheimer’s disease progression

Longitudinal subcortical volume changes and their correlations with multiple PET and fluid biomarkers in dominantly inherited Alzheimer’s disease