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Personal profile

Research interests

The development of genomics, bioinformatics and statistical methods as they apply to the study of cancer biology and medicine. A particular focus on the translation of genomics data from whole genome, exome and transcriptome sequencing into clinically actionable observations and personalized cancer therapies.

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Research Output

pVACtools: A Computational Toolkit to Identify and Visualize Cancer Neoantigens

Hundal, J., Kiwala, S., McMichael, J., Miller, C. A., Xia, H., Wollam, A. T., Liu, C. J., Zhao, S., Feng, Y. Y., Graubert, A. P., Wollam, A. Z., Neichin, J., Neveau, M., Walker, J., Gillanders, W. E., Mardis, E. R., Griffith, O. L. & Griffith, M., Mar 1 2020, In : Cancer immunology research. 8, 3, p. 409-420 12 p.

Research output: Contribution to journalArticle

Open Access
  • Reply

    Barnell, E. K., Kang, Y., Wurtzler, E. M., Griffith, M., Chaudhuri, A. A. & Griffith, O. L., Feb 2020, In : Gastroenterology. 158, 3, p. 793-794 2 p.

    Research output: Contribution to journalLetter

    Open Access

    Accounting for proximal variants improves neoantigen prediction

    Hundal, J., Kiwala, S., Feng, Y. Y., Liu, C. J., Govindan, R., Chapman, W. C., Uppaluri, R., Swamidass, S. J., Griffith, O. L., Mardis, E. R. & Griffith, M., Jan 1 2019, In : Nature Genetics. 51, 1, p. 175-179 5 p.

    Research output: Contribution to journalArticle

  • 9 Scopus citations

    A Spontaneous Aggressive ERα+ Mammary Tumor Model Is Driven by Kras Activation

    Campbell, K. M., O'Leary, K. A., Rugowski, D. E., Mulligan, W. A., Barnell, E. K., Skidmore, Z. L., Krysiak, K., Griffith, M., Schuler, L. A. & Griffith, O. L., Aug 6 2019, In : Cell Reports. 28, 6, p. 1526-1537.e4

    Research output: Contribution to journalArticle

    Open Access
  • 1 Scopus citations

    Best practices for bioinformatic characterization of neoantigens for clinical utility

    Richters, M. M., Xia, H., Campbell, K. M., Gillanders, W. E., Griffith, O. L. & Griffith, M., Aug 28 2019, In : Genome medicine. 11, 1, 56.

    Research output: Contribution to journalReview article

    Open Access
  • 4 Scopus citations