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Personal profile

Research interests

The development of genomics, bioinformatics and statistical methods as they apply to the study of cancer biology and medicine. A particular focus on the translation of genomics data from whole genome, exome and transcriptome sequencing into clinically actionable observations and personalized cancer therapies.

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Projects

Research Output

A harmonized meta-knowledgebase of clinical interpretations of somatic genomic variants in cancer

Variant Interpretation for Cancer Consortium, Apr 1 2020, In : Nature Genetics. 52, 4, p. 448-457 10 p.

Research output: Contribution to journalArticle

Open Access
  • pVACtools: A Computational Toolkit to Identify and Visualize Cancer Neoantigens

    Hundal, J., Kiwala, S., McMichael, J., Miller, C. A., Xia, H., Wollam, A. T., Liu, C. J., Zhao, S., Feng, Y. Y., Graubert, A. P., Wollam, A. Z., Neichin, J., Neveau, M., Walker, J., Gillanders, W. E., Mardis, E. R., Griffith, O. L. & Griffith, M., Mar 1 2020, In : Cancer immunology research. 8, 3, p. 409-420 12 p.

    Research output: Contribution to journalArticle

    Open Access
  • 2 Scopus citations

    Reply

    Barnell, E. K., Kang, Y., Wurtzler, E. M., Griffith, M., Chaudhuri, A. A. & Griffith, O. L., Feb 2020, In : Gastroenterology. 158, 3, p. 793-794 2 p.

    Research output: Contribution to journalLetter

    Open Access

    The clonal evolution of metastatic colorectal cancer

    Dang, H. X., Krasnick, B. A., White, B. S., Grossman, J. G., Strand, M. S., Zhang, J., Cabanski, C. R., Miller, C. A., Fulton, R. S., Goedegebuure, S. P., Fronick, C. C., Griffith, M., Larson, D. E., Goetz, B. D., Walker, J. R., Hawkins, W. G., Strasberg, S. M., Linehan, D. C., Lim, K-H., Lockhart, A. C. & 5 others, Mardis, E. R., Wilson, R. K., Ley, T. J., Maher, C. A. & Fields, R. C., Jun 2020, In : Science Advances. 6, 24, eaay9691.

    Research output: Contribution to journalArticle

    Open Access
  • Wikidata as a knowledge graph for the life sciences

    Waagmeester, A., Stupp, G., Burgstaller-Muehlbacher, S., Good, B. M., Griffith, M., Griffith, O. L., Hanspers, K., Hermjakob, H., Hudson, T. S., Hybiske, K., Keating, S. M., Manske, M., Mayers, M., Mietchen, D., Mitraka, E., Pico, A. R., Putman, T., Riutta, A., Queralt-Rosinach, N., Schriml, L. M. & 10 others, Shafee, T., Slenter, D., Stephan, R., Thornton, K., Tsueng, G., Tu, R., Ul-Hasan, S., Willighagen, E., Wu, C. & Su, A. I., Mar 2020, In : eLife. 9, e52614.

    Research output: Contribution to journalArticle

    Open Access