Research output per year
Research output per year
Personal profile
Research interests
The development of genomics, bioinformatics and statistical methods as they apply to the study of cancer biology and medicine. A particular focus on the translation of genomics data from whole genome, exome and transcriptome sequencing into clinically actionable observations and personalized cancer therapies.
Mentoring
The GriffithLab is an interdisciplinary team of biologists, bioinformaticians, computer scientists, and software engineers. Each member of the lab is trained to use computational biology approaches to address research questions relating to cancer biology and precision cancer medicine. We train students and post-docs with a biology background that would like to develop bioinformatics skills. We are equally interested in trainees with a computer science background that would like to apply these skills to studying cancer and improving patient outcomes.
Available to Mentor:
- PhD/MSTP Students
Fingerprint
Dive into the research topics where Malachi Griffith is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
A macrophage-cell model of HIV latency reveals the unusual importance of the bromodomain axis
Kisaka, J. K., Rauch, D., Griffith, M. & Kyei, G. B., Dec 2024, In: Virology Journal. 21, 1, 80.Research output: Contribution to journal › Article › peer-review
Open Access -
DGIdb 5.0: rebuilding the drug-gene interaction database for precision medicineãnd drug discovery platforms
Cannon, M., Stevenson, J., Stahl, K., Basu, R., Coffman, A., Kiwala, S., McMichael, J. F., Kuzma, K., Morrissey, D., Cotto, K., Mardis, E. R., Griffith, O. L., Griffith, M. & Wagner, A. H., Jan 5 2024, In: Nucleic acids research. 52, D1, p. D1227-D1235Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Single-cell T-cell receptor repertoire profiling in dogs
Hoang, M. H., Skidmore, Z. L., Rindt, H., Chu, S., Fisk, B., Foltz, J. A., Fronick, C., Fulton, R., Zhou, M., Bivens, N. J., Reinero, C. N., Fehniger, T. A., Griffith, M., Bryan, J. N. & Griffith, O. L., Dec 2024, In: Communications Biology. 7, 1, 484.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Autologous humanized PDX modeling for immuno-oncology recapitulates features of the human tumor microenvironment
Chiorazzi, M., Martinek, J., Krasnick, B., Zheng, Y., Robbins, K. J., Qu, R., Kaufmann, G., Skidmore, Z., Juric, M., Henze, L. A., Brösecke, F., Adonyi, A., Zhao, J., Shan, L., Sefik, E., Mudd, J., Bi, Y., Goedegebuure, S. P., Griffith, M. & Griffith, O. & 14 others, , Jul 24 2023, In: Journal for ImmunoTherapy of Cancer. 11, 7, e006921.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
CIViCdb 2022: evolution of an open-access cancer variant interpretation knowledgebase
Krysiak, K., Danos, A. M., Saliba, J., McMichael, J. F., Coffman, A. C., Kiwala, S., Barnell, E. K., Sheta, L., Grisdale, C. J., Kujan, L., Pema, S., Lever, J., Ridd, S., Spies, N. C., Andric, V., Chiorean, A., Rieke, D. T., Clark, K. A., Reisle, C. & Venigalla, A. C. & 45 others, , Jan 6 2023, In: Nucleic acids research. 51, 1 D, p. D1230-D1241Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations