Research output per year
Research output per year
- 27 results
Search results
-
2022
Distinguishing Tumor Admixed in a Radiation Necrosis (RN) Background: 1H and 2H MR With a Novel Mouse Brain-Tumor/RN Model
Ge, X., Song, K. H., Engelbach, J. A., Yuan, L., Gao, F., Dahiya, S., Rich, K. M., Ackerman, J. J. H. & Garbow, J. R., May 30 2022, In: Frontiers in Oncology. 12, 885480.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
2021
Irradiation-Modulated Murine Brain Microenvironment Enhances GL261-Tumor Growth and Inhibits Anti-PD-L1 Immunotherapy
Garbow, J. R., Johanns, T. M., Ge, X., Engelbach, J. A., Yuan, L., Dahiya, S., Tsien, C. I., Gao, F., Rich, K. M. & Ackerman, J. J. H., Jun 24 2021, In: Frontiers in Oncology. 11, 693146.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
2019
Late Effects of Radiation Prime the Brain Microenvironment for Accelerated Tumor Growth
Duan, C., Yang, R., Yuan, L., Engelbach, J. A., Tsien, C. I., Rich, K. M., Dahiya, S. M., Johanns, T. M., Ackerman, J. J. H. & Garbow, J. R., Jan 1 2019, In: International Journal of Radiation Oncology Biology Physics. 103, 1, p. 190-194 5 p.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
2018
Inhibitors of HIF-1α and CXCR4 Mitigate the Development of Radiation Necrosis in Mouse Brain
Yang, R., Duan, C., Yuan, L., Engelbach, J. A., Tsien, C. I., Beeman, S. C., Perez-Torres, C. J., Ge, X., Rich, K. M., Ackerman, J. J. H. & Garbow, J. R., Mar 15 2018, In: International Journal of Radiation Oncology Biology Physics. 100, 4, p. 1016-1025 10 p.Research output: Contribution to journal › Article › peer-review
Open Access30 Scopus citations -
2017
Can anti-vascular endothelial growth factor antibody reverse radiation necrosis? A preclinical investigation
Duan, C., Perez-Torres, C. J., Yuan, L., Engelbach, J. A., Beeman, S. C., Tsien, C. I., Rich, K. M., Schmidt, R. E., Ackerman, J. J. H. & Garbow, J. R., May 1 2017, In: Journal of Neuro-Oncology. 133, 1, p. 9-16 8 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
2016
An NAD+-dependent transcriptional program governs self-renewal and radiation resistance in glioblastoma
Gujar, A. D., Le, S., Mao, D. D., Dadey, D. Y. A., Turski, A., Sasaki, Y., Aum, D., Luo, J., Dahiya, S., Yuan, L., Rich, K., Milbrandt, J., Hallahan, D. E., Yano, H., Tran, D. D. & Kim, A. H., Dec 20 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 51, p. E8247-E8256Research output: Contribution to journal › Article › peer-review
Open Access105 Scopus citations -
Effect of α-Methyl versus α-Hydrogen Substitution on Brain Availability and Tumor Imaging Properties of Heptanoic [F-18]Fluoroalkyl Amino Acids for Positron Emission Tomography (PET)
Bouhlel, A., Alyami, W., Li, A., Yuan, L., Rich, K. & McConathy, J., Apr 28 2016, In: Journal of Medicinal Chemistry. 59, 7, p. 3515-3531 17 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
2015
A gamma-knife-enabled mouse model of cerebral single-hemisphere delayed radiation necrosis
Jiang, X., Yuan, L., Engelbach, J. A., Cates, J., Perez-Torres, C. J., Gao, F., Thotala, D., Drzymala, R. E., Schmidt, R. E., Rich, K., Hallahan, D. E., Ackerman, J. J. H. & Garbow, J. R., Oct 6 2015, In: PloS one. 10, 10, e0139596.Research output: Contribution to journal › Article › peer-review
Open Access32 Scopus citations -
Perilesional edema in radiation necrosis reflects axonal degeneration
Perez-Torres, C. J., Yuan, L., Schmidt, R. E., Rich, K. M., Ackerman, J. J. H. & Garbow, J. R., Jan 31 2015, In: Radiation Oncology. 10, 1, 33.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Specificity of vascular endothelial growth factor treatment for radiation necrosis
Perez-Torres, C. J., Yuan, L., Schmidt, R. E., Rich, K. M., Drzymala, R. E., Hallahan, D. E., Ackerman, J. J. H. & Garbow, J. R., Nov 1 2015, In: Radiotherapy and Oncology. 117, 2, p. 382-385 4 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
Synthesis, radiolabeling, and biological evaluation of (R)- and (S)-2-amino-5-[18F]fluoro-2-methylpentanoic acid ((R)-, (S)-[18F]FAMPe) as potential positron emission tomography tracers for brain tumors
Bouhlel, A., Zhou, D., Li, A., Yuan, L., Rich, K. M. & McConathy, J., May 14 2015, In: Journal of Medicinal Chemistry. 58, 9, p. 3817-3829 13 p.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
Synthesis and Biological Evaluation of (S)-Amino-2-methyl-4-[76Br]bromo-3-(E)-butenoic Acid (BrVAIB) for Brain Tumor Imaging
Bartels, J. L., Huang, C., Li, A., Yuan, L., Rich, K., McConathy, J. & Lapi, S. E., Oct 7 2015, In: Journal of Medicinal Chemistry. 58, 21, p. 8542-8552 11 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
2014
A GSK-3β inhibitor protects against radiation necrosis in mouse brain
Jiang, X., Perez-Torres, C. J., Thotala, D., Engelbach, J. A., Yuan, L., Cates, J., Gao, F., Drzymala, R. E., Rich, K., Schmidt, R. E., Ackerman, J. J. H., Hallahan, D. E. & Garbow, J. R., Jul 15 2014, In: International Journal of Radiation Oncology Biology Physics. 89, 4, p. 714-721 8 p.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
Anti-VEGF antibodies mitigate the development of radiation necrosis in mouse brain
Jiang, X., Engelbach, J. A., Yuan, L., Cates, J., Gao, F., Drzymala, R. E., Hallahan, D. E., Rich, K., Schmidt, R. E., Ackerman, J. J. H. & Garbow, J. R., May 15 2014, In: Clinical Cancer Research. 20, 10, p. 2695-2702 8 p.Research output: Contribution to journal › Article › peer-review
Open Access69 Scopus citations -
Toward distinguishing recurrent tumor from radiation necrosis: DWI and MTC in a gamma knife-irradiated mouse glioma model
Perez-Torres, C. J., Engelbach, J. A., Cates, J., Thotala, D., Yuan, L., Schmidt, R. E., Rich, K. M., Drzymala, R. E., Ackerman, J. J. H. & Garbow, J. R., Oct 1 2014, In: International Journal of Radiation Oncology Biology Physics. 90, 2, p. 446-453 8 p.Research output: Contribution to journal › Article › peer-review
Open Access32 Scopus citations -
2013
18F-AFETP, 18F-FET, and 18F-FDG imaging of mouse DBT gliomas
Sai, K. K. S., Huang, C., Yuan, L., Zhou, D., Piwnica-Worms, D., Garbow, J. R., Engelbach, J. A., Mach, R. H., Rich, K. M. & Mcconathy, J., Jul 1 2013, In: Journal of Nuclear Medicine. 54, 7, p. 1120-1126 7 p.Research output: Contribution to journal › Article › peer-review
Open Access27 Scopus citations -
Radiosynthesis and biological evaluation of alpha-[F-18]fluoromethyl phenylalanine for brain tumor imaging
Huang, C., Yuan, L., Rich, K. M. & McConathy, J., May 2013, In: Nuclear Medicine and Biology. 40, 4, p. 498-506 9 p.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
2011
Novel chemo-sensitizing agent, ERW1227B, impairs cellular motility and enhances cell death in glioblastomas
Yuan, L., Holmes, T. C., Watts, R. E., Khosla, C., Broekelmann, T. J., Mecham, R., Zheng, H., Izaguirre, E. W. & Rich, K. M., Jun 2011, In: Journal of Neuro-Oncology. 103, 2, p. 207-219 13 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
2009
Down-regulation of Rap1GAP via promoter hypermethylation promotes melanoma cell proliferation, survival, and migration
Zheng, H., Gao, L., Feng, Y., Yuan, L., Zhao, H. & Cornelius, L. A., Jan 15 2009, In: Cancer research. 69, 2, p. 449-457 9 p.Research output: Contribution to journal › Article › peer-review
Open Access76 Scopus citations -
2008
Tissue transgluaminase 2 expression in meningiomas
Yuan, L., Behdad, A., Siegel, M., Khosla, C., Higashikubo, R. & Rich, K. M., 2008, In: Journal of Neuro-Oncology. 90, 2, p. 125-132 8 p.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
2007
Identification of photoreceptor genes affected by PRPF31 mutations associated with autosomal dominant retinitis pigmentosa
Mordes, D., Yuan, L., Xu, L., Kawada, M., Molday, R. S. & Wu, J. Y., May 2007, In: Neurobiology of Disease. 26, 2, p. 291-300 10 p.Research output: Contribution to journal › Article › peer-review
29 Scopus citations -
Transglutaminase 2 inhibitor, KCC009, disrupts fibronectin assembly in the extracellular matrix and sensitizes orthotopic glioblastomas to chemotherapy
Yuan, L., Siegel, M., Choi, K., Khosla, C., Miller, C. R., Jackson, E. N., Piwnica-Worms, D. & Rich, K. M., Apr 19 2007, In: Oncogene. 26, 18, p. 2563-2573 11 p.Research output: Contribution to journal › Article › peer-review
153 Scopus citations -
2005
Chemistry and biology of dihydroisoxazole derivatives: Selective inhibitors of human transglutaminase 2
Choi, K., Siegel, M., Piper, J. L., Yuan, L., Cho, E., Strnad, P., Omary, B., Rich, K. M. & Khosla, C., Apr 2005, In: Chemistry and Biology. 12, 4, p. 469-475 7 p.Research output: Contribution to journal › Article › peer-review
Open Access152 Scopus citations -
Mutations in PRPF31 inhibit pre-mRNA splicing of rhodopsin gene and cause apoptosis of retinal cells
Yuan, L., Kawada, M., Havlioglu, N., Tang, H. & Wu, J. Y., Jan 19 2005, In: Journal of Neuroscience. 25, 3, p. 748-757 10 p.Research output: Contribution to journal › Article › peer-review
Open Access61 Scopus citations -
Tissue transglutaminase 2 inhibition promotes cell death and chemosensitivity in glioblastomas
Yuan, L., Choi, K., Khosla, C., Zheng, X., Higashikubo, R., Chicoine, M. R. & Rich, K. M., Sep 2005, In: Molecular Cancer Therapeutics. 4, 9, p. 1293-1302 10 p.Research output: Contribution to journal › Article › peer-review
83 Scopus citations -
2001
Activated microglia in the human glaucomatous optic nerve head
Yuan, L. & Neufeld, A. H., Jun 1 2001, In: Journal of Neuroscience Research. 64, 5, p. 523-532 10 p.Research output: Contribution to journal › Article › peer-review
294 Scopus citations -
2000
Tumor necrosis factor-α: A potentially neurodestructive cytokine produced by glia in the human glaucomatous optic nerve head
Yuan, L. & Neufeld, A. H., 2000, In: Glia. 32, 1, p. 42-50 9 p.Research output: Contribution to journal › Article › peer-review
289 Scopus citations