Personal profile

Research interests

Linying Zhang, PhD, is Assistant Professor of Biostatistics in the Institute for Informatics, Data Science, and Biostatistics (I2DB) at Washington University School of Medicine in St. Louis. Dr. Zhang specializes in causal inference and machine learning for generating reliable real-world evidence from large-scale healthcare databases, such as electronic health records (EHRs) and administrative claims. Her recent research has focused on addressing confounding bias in observational studies, and explaining root causes of treatment disparities from a causal perspective. Her research goals include 1) developing federated causal machine learning for treatment effect estimation across multiple databases without sharing patient-level data, 2) developing heterogeneous and individualized treatment effect estimation algorithms for personalized treatment planning, and 3) improving the equity of health care through machine learning. She is open to mentor undergraduate and graduate students, and post-doctoral fellows. Dr. Zhang has a PhD in Biomedical Informatics from Columbia University, MS in Computational Biology from Harvard University, and BA in Biochemistry and Molecular Biology from Boston University.

Available to Mentor:

  • PhD Students

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  • Assessing Covariate Balance With Small Sample Sizes

    Hripcsak, G., Zhang, L., Chen, Y., Li, K., Suchard, M. A., Ryan, P. B. & Schuemie, M. J., Aug 2025, In: Statistics in medicine. 44, 18-19, e70212.

    Research output: Contribution to journalArticlepeer-review

  • Reply

    Cai, C. X., Zhang, L. & Hripcsak, G., Mar 2025, In: Ophthalmology Retina. 9, 3, p. e17-e18

    Research output: Contribution to journalLetterpeer-review

  • Semaglutide and Nonarteritic Anterior Ischemic Optic Neuropathy

    Cai, C. X., Hribar, M., Baxter, S., Goetz, K., Swaminathan, S. S., Flowers, A., Brown, E. N., Toy, B., Xu, B., Chen, J., Chen, A., Wang, S., Lee, C., Leng, T., Ehrlich, J. R., Barkmeier, A., Armbrust, K. R., Boland, M. V., Dorr, D. & Boyce, D. & 38 others, Alshammari, T., Swerdel, J., Suchard, M. A., Schuemie, M., Bu, F., Sena, A. G., Hripcsak, G., Nishimura, A., Nagy, P., Falconer, T., Duvall, S. L., Matheny, M., Viernes, B., O'Brien, W., Zhang, L., Martin, B., Westlund, E., Mathioudakis, N., Fan, R., Wilcox, A., Lai, A., Stocking, J. C., Takkouche, S., Lee, L. H., Xie, Y., Humes, I., McCoy, D. B., Adibuzzaman, M., Areaux, R. G., Rojas-Carabali, W., Brash, J., Lee, D. A., Weiskopf, N. G., Mawn, L., Agrawal, R., Morgan-Cooper, H., Desai, P. & Ryan, P. B., Apr 17 2025, In: JAMA Ophthalmology. 143, 4, p. 304-314 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    39 Scopus citations
  • Causal fairness assessment of treatment allocation with electronic health records

    Zhang, L., Richter, L. R., Wang, Y., Ostropolets, A., Elhadad, N., Blei, D. M. & Hripcsak, G., Jul 2024, In: Journal of Biomedical Informatics. 155, 104656.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    4 Scopus citations
  • Evaluating and Improvi g the Performance and Racial Fairness of Algori ims for GFR Estimation

    Zhang, L., Kim, T., Richter, L. R. & Hripcsak, G., 2024, Proceedings - 2024 IEEE 1st International Conference on Artificial Intelligence for Medicine, Health and Care, AIMHC 2024. Institute of Electrical and Electronics Engineers Inc., p. 251-257 7 p. (Proceedings - 2024 IEEE 1st International Conference on Artificial Intelligence for Medicine, Health and Care, AIMHC 2024).

    Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

    Open Access
    1 Scopus citations