Personal profile

Research interests

Our research focusses on the development, plasticity, and function of long-range connections of the cerebral cortex. The corpus callosum is the largest fibre tract in the brain of placental mammals and connects neurons in each cortical hemisphere. We investigate how cellular and molecular/genetic mechanisms regulate brain wiring during development and how brain wiring is altered in congenital corpus callosum dysgenesis (CCD). CCD occurs in 1:4000 people and can result in profound changes in the structural architecture of brain connectivity due to long-range axonal plasticity that occurs during development. Our research investigates the underlying causes of CCD, how long-range axonal plasticity occurs and how these structural changes in brain wiring impact cognition and behaviour. Professor Richards is a board member of the International Research Consortium for the Corpus Callosum and Cerebral Connectivity (IRC5) and a scientific advisor and patron of Australian Disorders of the Corpus Callosum (AusDoCC) support group. In addition to her research, Professor Richards is a passionate advocate for neuroscience. She contributed to establishing the International Brain Initiative, the Australian Brain Alliance and the Australian Brain Bee Challenge. Other Links: Department of Neuroscience McDonnell Center for Cellular & Molecular Neurobiology

Mentoring

Good mentorship is critical to academic science. I find incredible joy in mentoring students, fellows, staff and faculty and to support them to achieve their goals throughout their career. I strive to create an inclusive environment where all members feel that they can contribute their ideas and help shape our research and their own working environment. Each member of our team brings their own background and experiences to our laboratory and Department and we want to make the most of all our talent to tackle the biggest questions. Collectively, our purpose is to advance discoveries to understand the brain and I feel privileged to work with my colleagues to achieve great things together. We celebrate our accomplishments and we support one another. 

Available to Mentor:

  • PhD/MSTP Students

Fingerprint

Dive into the research topics where Linda Richards is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
  • 1 Similar Profiles

Collaborations and top research areas from the last five years

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
  • Diverse axonal morphologies of individual callosal projection neurons reveal new insights into brain connectivity

    Pal, S., Lim, J. W. C. & Richards, L. J., Feb 2024, In: Current Opinion in Neurobiology. 84, 102837.

    Research output: Contribution to journalReview articlepeer-review

  • Aicardi Syndrome Is a Genetically Heterogeneous Disorder

    Ha, T. T., Burgess, R., Newman, M., Moey, C., Mandelstam, S. A., Gardner, A. E., Ivancevic, A. M., Pham, D., Kumar, R., Smith, N., Patel, C., Malone, S., Ryan, M. M., Calvert, S., van Eyk, C. L., Lardelli, M., Berkovic, S. F., Leventer, R. J., Richards, L. J., Scheffer, I. E., & 2 othersGecz, J. & Corbett, M. A., Aug 2023, In: Genes. 14, 8, 1565.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Cortical activity emerges in region-specific patterns during early brain development

    Suárez, R., Bluett, T., McCullough, M. H., Avitan, L., Black, D. A., Paolino, A., Fenlon, L. R., Goodhill, G. J. & Richards, L. J., May 30 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 22, e2208654120.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    2 Scopus citations
  • Functional and clinical studies reveal pathophysiological complexity of CLCN4-related neurodevelopmental condition

    Palmer, E. E., Pusch, M., Picollo, A., Forwood, C., Nguyen, M. H., Suckow, V., Gibbons, J., Hoff, A., Sigfrid, L., Megarbane, A., Nizon, M., Cogné, B., Beneteau, C., Alkuraya, F. S., Chedrawi, A., Hashem, M. O., Stamberger, H., Weckhuysen, S., Vanlander, A., Ceulemans, B., & 79 othersRajagopalan, S., Nunn, K., Arpin, S., Raynaud, M., Motter, C. S., Ward-Melver, C., Janssens, K., Meuwissen, M., Beysen, D., Dikow, N., Grimmel, M., Haack, T. B., Clement, E., McTague, A., Hunt, D., Townshend, S., Ward, M., Richards, L. J., Simons, C., Costain, G., Dupuis, L., Mendoza-Londono, R., Dudding-Byth, T., Boyle, J., Saunders, C., Fleming, E., El Chehadeh, S., Spitz, M. A., Piton, A., Gerard, B., Abi Warde, M. T., Rea, G., McKenna, C., Douzgou, S., Banka, S., Akman, C., Bain, J. M., Sands, T. T., Wilson, G. N., Silvertooth, E. J., Miller, L., Lederer, D., Sachdev, R., Macintosh, R., Monestier, O., Karadurmus, D., Collins, F., Carter, M., Rohena, L., Willemsen, M. H., Ockeloen, C. W., Pfundt, R., Kroft, S. D., Field, M., Laranjeira, F. E. R., Fortuna, A. M., Soares, A. R., Michaud, V., Naudion, S., Golla, S., Weaver, D. D., Bird, L. M., Friedman, J., Clowes, V., Joss, S., Pölsler, L., Campeau, P. M., Blazo, M., Bijlsma, E. K., Rosenfeld, J. A., Beetz, C., Powis, Z., McWalter, K., Brandt, T., Torti, E., Mathot, M., Mohammad, S. S., Armstrong, R. & Kalscheuer, V. M., Feb 2023, In: Molecular Psychiatry. 28, 2, p. 668-697 30 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    11 Scopus citations
  • Loss-of-function variants in ZEB1 cause dominant anomalies of the corpus callosum with favourable cognitive prognosis

    Heide, S., Argilli, E., Valence, S., Boutaud, L., Roux, N., Mignot, C., Nava, C., Keren, B., Giraudat, K., Faudet, A., Gerasimenko, A., Garel, C., Blondiaux, E., Rastetter, A., Grevent, D., Le, C., Mackenzie, L., Richards, L., Attié-Bitach, T., Depienne, C., & 2 othersSherr, E. & Héron, D., Oct 19 2023, In: Journal of Medical Genetics. 61, 3, p. 244-249 6 p.

    Research output: Contribution to journalArticlepeer-review