• 3853
    Citations
1993 …2022

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Research interests

My main area of interest is understanding the mechanisms by which substrate metabolism affects structure and function. I use multiple imaging modalities including echocardiography, Positron Emission Tomography, Magnetic Resonance Imaging and Spectroscopy to translate findings from animal models to humans. Specific areas of research include: nitric oxide’s effects on skeletal muscle function in heart failure; the effects of metabolic modulation on cancer and diabetes; the effects of heart failure, sex, obesity, insulin resistance, and diabetes on myocardial substrate metabolism, structure, and function; and associations between specific lipids (ceramides) on cardiovascular outcomes. 

Clinical interests

Cardiac rehabilitation, heart failure; maximal oxygen uptake testing (VO2peak), echocardiography, cardio-oncology.

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