Lijin Li

2024

Neoantigen DNA vaccines are safe, feasible, and induce neoantigen-specific immune responses in triple-negative breast cancer patients

Zhang, X., Goedegebuure, S. P., Chen, M. Y., Mishra, R., Zhang, F., Yu, Y. Y., Singhal, K., Li, L., Gao, F., Myers, N. B., Vickery, T., Hundal, J., McLellan, M. D., Sturmoski, M. A., Kim, S. W., Chen, I., Davidson, J. T., Sankpal, N. V., Myles, S. & Suresh, R. & 13 others, Ma, C. X., Foluso, A., Wang-Gillam, A., Davies, S., Hagemann, I. S., Mardis, E. R., Griffith, O., Griffith, M., Miller, C. A., Hansen, T. H., Fleming, T. P., Schreiber, R. D. & Gillanders, W. E., Dec 2024, In: Genome medicine. 16, 1, 131.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

2023

Induction of cancer neoantigens facilitates development of clinically relevant models for the study of pancreatic cancer immunobiology

Panni, U. Y., Chen, M. Y., Zhang, F., Cullinan, D. R., Li, L., James, C. A., Zhang, X., Rogers, S., Alarcon, A., Baer, J. M., Zhang, D., Gao, F., Miller, C. A., Gong, Q., Lim, K. H., DeNardo, D. G., Goedegebuure, S. P., Gillanders, W. E. & Hawkins, W. G., Aug 2023, In: Cancer Immunology, Immunotherapy. 72, 8, p. 2813-2827 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

2022

Combination TIGIT/PD-1 blockade enhances the efficacy of neoantigen vaccines in a model of pancreatic cancer

Peng, H., Li, L., Zuo, C., Chen, M. Y., Zhang, X., Myers, N. B., Hogg, G. D., DeNardo, D. G., Goedegebuure, S. P., Hawkins, W. G. & Gillanders, W. E., Dec 8 2022, In: Frontiers in immunology. 13, 1039226.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

2021

Neoantigen vaccine platforms in clinical development: understanding the future of personalized immunotherapy

Supabphol, S., Li, L., Goedegebuure, S. P. & Gillanders, W. E., 2021, In: Expert Opinion on Investigational Drugs. 30, 5, p. 529-541 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

32 Scopus citations

Optimized polyepitope neoantigen DNA vaccines elicit neoantigen-specific immune responses in preclinical models and in clinical translation

Li, L., Zhang, X., Wang, X., Kim, S. W., Herndon, J. M., Becker-Hapak, M. K., Carreno, B. M., Myers, N. B., Sturmoski, M. A., McLellan, M. D., Miller, C. A., Johanns, T. M., Tan, B. R., Dunn, G. P., Fleming, T. P., Hansen, T. H., Goedegebuure, S. P. & Gillanders, W. E., Dec 2021, In: Genome medicine. 13, 1, 56.

Research output: Contribution to journal › Article › peer-review

Open Access

47 Scopus citations

2020

Cancer vaccines: shared tumor antigens return to the spotlight

Li, L., Goedegebuure, S. P. & Gillanders, W., Dec 1 2020, In: Signal Transduction and Targeted Therapy. 5, 1, 251.

Research output: Contribution to journal › Article › peer-review

Open Access

26 Scopus citations

cDC1 prime and are licensed by CD4⁺ T cells to induce anti-tumour immunity

Ferris, S. T., Durai, V., Wu, R., Theisen, D. J., Ward, J. P., Bern, M. D., Davidson, J. T., Bagadia, P., Liu, T., Briseño, C. G., Li, L., Gillanders, W. E., Wu, G. F., Yokoyama, W. M., Murphy, T. L., Schreiber, R. D. & Murphy, K. M., Aug 27 2020, In: Nature. 584, 7822, p. 624-629 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

359 Scopus citations

2018

Development of an adenovirus vector vaccine platform for targeting dendritic cells

Sharma, P. K., Dmitriev, I. P., Kashentseva, E. A., Raes, G., Li, L., Kim, S. W., Lu, Z. H., Arbeit, J. M., Fleming, T. P., Kaliberov, S. A., Goedegebuure, S. P., Curiel, D. T. & Gillanders, W. E., Feb 1 2018, In: Cancer gene therapy. 25, 1-2, p. 27-38 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

31 Scopus citations

2017

Breast cancer neoantigens can induce CD8⁺ T-cell responses and antitumor immunity

Zhang, X., Kim, S., Hundal, J., Herndon, J. M., Li, S., Petti, A. A., Soysal, S. D., Li, L., McLellan, M. D., Hoog, J., Primeau, T., Myers, N., Vickery, T. L., Sturmoski, M., Hagemann, I. S., Miller, C. A., Ellis, M. J., Mardis, E. R., Hansen, T. & Fleming, T. P. & 2 others, Goedegebuure, S. P. & Gillanders, W. E., Jul 2017, In: Cancer immunology research. 5, 7, p. 516-523 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

70 Scopus citations

Preclinical and clinical development of neoantigen vaccines

Li, L., Goedegebuure, S. P. & Gillanders, W. E., Dec 1 2017, In: Annals of Oncology. 28, p. xii11-xii17

Research output: Contribution to journal › Review article › peer-review

Open Access

180 Scopus citations

2015

Developing a clinical development paradigm for translation of a mammaglobin-A DNA vaccine

Li, L., Goedegebuure, S. P., Fleming, T. P. & Gillanders, W. E., Jul 1 2015, In: Immunotherapy. 7, 7, p. 709-711 3 p.

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

2014

Identification and translational validation of novel mammaglobin-A CD8 T cell epitopes

Soysal, S. D., Muenst, S., Kan-Mitchell, J., Huarte, E., Zhang, X., Wilkinson-Ryan, I., Fleming, T., Tiriveedhi, V., Mohanakumar, T., Li, L., Herndon, J., Oertli, D., Goedegebuure, S. P. & Gillanders, W. E., Sep 24 2014, In: Breast Cancer Research and Treatment. 147, 3, p. 527-537 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Safety and preliminary evidence of biologic efficacy of a mammaglobin-A DNA vaccine in patients with stable metastatic breast cancer

Tiriveedhi, V., Tucker, N., Herndon, J., Li, J., Sturmoski, M., Ellis, M., Ma, C., Naughton, M., Lockhart, A. C., Gao, F., Fleming, T., Goedegebuure, P., Mohanakumar, T. & Gillanders, W. E., Dec 1 2014, In: Clinical Cancer Research. 20, 23, p. 5964-5975 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

80 Scopus citations

2012

Cross-dressed CD8α⁺/CD103⁺ dendritic cells prime CD8⁺ T cells following vaccination

Li, J., Kim, S., Herndon, J. M., Goedegebuure, P., Belt, B. A., Satpathy, A. T., Fleming, T. P., Hansen, T. H., Murphy, K. M. & Gillanders, W. E., Jul 31 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 31, p. 12716-12721 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

68 Scopus citations

2011

Cancer genome sequencing and its implications for personalized cancer vaccines

Li, L., Goedegebuure, P., Mardis, E. R., Ellis, M. J. C., Zhang, X., Herndon, J. M., Fleming, T. P., Carreno, B. M., Hansen, T. H. & Gillanders, W. E., Dec 2011, In: Cancers. 3, 4, p. 4191-4211 21 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

25 Scopus citations

2010

Engineering superior DNA vaccines: MHC class I single chain trimers bypass antigen processing and enhance the immune response to low affinity antigens

Li, L., Herndon, J. M., Truscott, S. M., Hansen, T. H., Fleming, T. P., Goedegebuure, P. & Gillanders, W. E., Feb 23 2010, In: Vaccine. 28, 8, p. 1911-1918 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

17 Scopus citations

Single-chain HLA-A2 MHC trimers that incorporate an immundominant peptide elicit protective T cell immunity against lethal West Nile virus infection

Kim, S., Li, J., McMurtrey, C. P., Hildebrand, W. H., Weidanz, J. A., Gillanders, W. E., Diamond, M. S. & Hansen, T. H., Apr 15 2010, In: Journal of Immunology. 184, 8, p. 4423-4430 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

44 Scopus citations

2005

Cellular immune suppressor activity resides in lymphocyte cell clusters adjacent to granulomata in human coccidioidomycosis

Li, L., Dial, S. M., Schmelz, M., Rennels, M. A. & Ampel, N. M., Jul 2005, In: Infection and immunity. 73, 7, p. 3923-3928 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

34 Scopus citations

Preliminary evaluation of whole-blood gamma interferon release for clinical assessment of cellular immunity in patients with active coccidioidomycosis

Ampel, N. M., Nelson, D. K., Chavez, S., Naus, K. A., Herman, A. B., Li, L., Simmons, K. A. & Pappagianis, D., Jun 2005, In: Clinical and Diagnostic Laboratory Immunology. 12, 6, p. 700-704 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

The mannose receptor mediates the cellular immune response in human coccidioidomycosis

Ampel, N. M., Nelson, D. K., Li, L., Dionne, S. O., Lake, D. F., Simmons, K. A. & Pappagianis, D., Apr 2005, In: Infection and immunity. 73, 4, p. 2554-2555 2 p.

Research output: Contribution to journal › Article › peer-review

Open Access

23 Scopus citations

2002

In vitro whole-blood analysis of cellular immunity in patients with active coccidioidomycosis by using the antigen preparation T27K

Ampel, N. M., Kramer, L. A., Li, L., Carroll, D. S., Kerekes, K. M., Johnson, S. M. & Pappagianis, D., Sep 2002, In: Clinical and Diagnostic Laboratory Immunology. 9, 5, p. 1039-1043 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

27 Scopus citations

Lijin Li

Research output

Search results