Li Ding

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Li Ding

David English Smith Professorship in Medicine #3, Professor of Medicine, Professor of Genetics

 https://orcid.org/0000-0003-1517-2975

    Willing to Mentor

    Available to Mentor:

    PhD/MSTP Students

    • 183813
      Citations
    1996 …2024

    Research activity per year

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    • 2023

      Animal Models and Their Role in Imaging-Assisted Co-Clinical Trials

      Peehl, D. M., Badea, C. T., Chenevert, T. L., Daldrup-Link, H. E., Ding, L., Dobrolecki, L. E., Houghton, A. M. G., Kinahan, P. E., Kurhanewicz, J., Lewis, M. T., Li, S., Luker, G. D., Ma, C. X., Manning, H. C., Mowery, Y. M., O’Dwyer, P. J., Pautler, R. G., Rosen, M. A., Roudi, R. & Ross, B. D. & 5 others, Shoghi, K. I., Sriram, R., Talpaz, M., Wahl, R. L. & Zhou, R., Apr 2023, In: Tomography (Ann Arbor, Mich.). 9, 2, p. 657-680 24 p.

      Research output: Contribution to journal › Review article › peer-review

      Open Access
      3 Scopus citations

    • Proteogenomic data and resources for pan-cancer analysis

      Clinical Proteomic Tumor Analysis Consortium, Aug 14 2023, In: Cancer Cell. 41, 8, p. 1397-1406 10 p.

      Research output: Contribution to journal › Review article › peer-review

      Open Access
      27 Scopus citations
    • 2022

      Cancer proteogenomics: current impact and future prospects

      Mani, D. R., Krug, K., Zhang, B., Satpathy, S., Clauser, K. R., Ding, L., Ellis, M., Gillette, M. A. & Carr, S. A., May 2022, In: Nature Reviews Cancer. 22, 5, p. 298-313 16 p.

      Research output: Contribution to journal › Review article › peer-review

      94 Scopus citations
    • 2021

      Moving pan-cancer studies from basic research toward the clinic

      Chen, F., Wendl, M. C., Wyczalkowski, M. A., Bailey, M. H., Li, Y. & Ding, L., Sep 2021, In: Nature Cancer. 2, 9, p. 879-890 12 p.

      Research output: Contribution to journal › Review article › peer-review

      47 Scopus citations

    • RNA splicing and immune-checkpoint inhibition

      Ding, L. & Odunsi, K., Nov 4 2021, In: New England Journal of Medicine. 385, 19, p. 1807-1809 3 p.

      Research output: Contribution to journal › Review article › peer-review

      3 Scopus citations
    • 2020

      The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution

      Human Tumor Atlas Network, Apr 16 2020, In: Cell. 181, 2, p. 236-249 14 p.

      Research output: Contribution to journal › Review article › peer-review

      Open Access
      279 Scopus citations

    • Tumor-on-a-chip platform to interrogate the role of macrophages in tumor progression

      Bi, Y., Shirure, V. S., Liu, R., Cunningham, C., Ding, L., Meacham, J. M., Goedegebuure, S. P., George, S. C. & Fields, R. C., Sep 1 2020, In: Integrative Biology. 12, 9, p. 221-232 12 p.

      Research output: Contribution to journal › Review article › peer-review

      Open Access
      42 Scopus citations
    • 2015

      A global reference for human genetic variation

      Auton, A., Abecasis, G. R., Altshuler, D. M., Durbin, R. M., Bentley, D. R., Chakravarti, A., Clark, A. G., Donnelly, P., Eichler, E. E., Flicek, P., Gabriel, S. B., Gibbs, R. A., Green, E. D., Hurles, M. E., Knoppers, B. M., Korbel, J. O., Lander, E. S., Lee, C., Lehrach, H. & Mardis, E. R. & 457 others, Marth, G. T., McVean, G. A., Nickerson, D. A., Schmidt, J. P., Sherry, S. T., Wang, J., Wilson, R. K., Boerwinkle, E., Doddapaneni, H., Han, Y., Korchina, V., Kovar, C., Lee, S., Muzny, D., Reid, J. G., Zhu, Y., Chang, Y., Feng, Q., Fang, X., Guo, X., Jian, M., Jiang, H., Jin, X., Lan, T., Li, G., Li, J., Li, Y., Liu, S., Liu, X., Lu, Y., Ma, X., Tang, M., Wang, B., Wang, G., Wu, H., Wu, R., Xu, X., Yin, Y., Zhang, D., Zhang, W., Zhao, J., Zhao, M., Zheng, X., Gupta, N., Gharani, N., Toji, L. H., Gerry, N. P., Resch, A. M., Barker, J., Clarke, L., Gil, L., Hunt, S. E., Kelman, G., Kulesha, E., Leinonen, R., McLaren, W. M., Radhakrishnan, R., Roa, A., Smirnov, D., Smith, R. E., Streeter, I., Thormann, A., Toneva, I., Vaughan, B., Zheng-Bradley, X., Grocock, R., Humphray, S., James, T., Kingsbury, Z., Sudbrak, R., Albrecht, M. W., Amstislavskiy, V. S., Borodina, T. A., Lienhard, M., Mertes, F., Sultan, M., Timmermann, B., Yaspo, M. L., Fulton, L., Ananiev, V., Belaia, Z., Beloslyudtsev, D., Bouk, N., Chen, C., Church, D., Cohen, R., Cook, C., Garner, J., Hefferon, T., Kimelman, M., Liu, C., Lopez, J., Meric, P., O'Sullivan, C., Ostapchuk, Y., Phan, L., Ponomarov, S., Schneider, V., Shekhtman, E., Sirotkin, K., Slotta, D., Zhang, H., Balasubramaniam, S., Burton, J., Danecek, P., Keane, T. M., Kolb-Kokocinski, A., McCarthy, S., Stalker, J., Quail, M., Davies, C. J., Gollub, J., Webster, T., Wong, B., Zhan, Y., Campbell, C. L., Kong, Y., Marcketta, A., Yu, F., Antunes, L., Bainbridge, M., Sabo, A., Huang, Z., Coin, L. J. M., Fang, L., Li, Q., Li, Z., Lin, H., Liu, B., Luo, R., Shao, H., Xie, Y., Ye, C., Yu, C., Zhang, F., Zheng, H., Zhu, H., Alkan, C., Dal, E., Kahveci, F., Garrison, E. P., Kural, D., Lee, W. P., Leong, W. F., Stromberg, M., Ward, A. N., Wu, J., Zhang, M., Daly, M. J., DePristo, M. A., Handsaker, R. E., Banks, E., Bhatia, G., Del Angel, G., Genovese, G., Li, H., Kashin, S., McCarroll, S. A., Nemesh, J. C., Poplin, R. E., Yoon, S. C., Lihm, J., Makarov, V., Gottipati, S., Keinan, A., Rodriguez-Flores, J. L., Rausch, T., Fritz, M. H., Stütz, A. M., Beal, K., Datta, A., Herrero, J., Ritchie, G. R. S., Zerbino, D., Sabeti, P. C., Shlyakhter, I., Schaffner, S. F., Vitti, J., Cooper, D. N., Ball, E. V., Stenson, P. D., Barnes, B., Bauer, M., Cheetham, R. K., Cox, A., Eberle, M., Kahn, S., Murray, L., Peden, J., Shaw, R., Kenny, E. E., Batzer, M. A., Konkel, M. K., Walker, J. A., MacArthur, D. G., Lek, M., Herwig, R., Ding, L., Koboldt, D. C., Larson, D., Ye, K., Gravel, S., Swaroop, A., Chew, E., Lappalainen, T., Erlich, Y., Gymrek, M., Willems, T. F., Simpson, J. T., Shriver, M. D., Rosenfeld, J. A., Bustamante, C. D., Montgomery, S. B., De La Vega, F. M., Byrnes, J. K., Carroll, A. W., DeGorter, M. K., Lacroute, P., Maples, B. K., Martin, A. R., Moreno-Estrada, A., Shringarpure, S. S., Zakharia, F., Halperin, E., Baran, Y., Cerveira, E., Hwang, J., Malhotra, A., Plewczynski, D., Radew, K., Romanovitch, M., Zhang, C., Hyland, F. C. L., Craig, D. W., Christoforides, A., Homer, N., Izatt, T., Kurdoglu, A. A., Sinari, S. A., Squire, K., Xiao, C., Sebat, J., Antaki, D., Gujral, M., Noor, A., Ye, K., Burchard, E. G., Hernandez, R. D., Gignoux, C. R., Haussler, D., Katzman, S. J., Kent, W. J., Howie, B., Ruiz-Linares, A., Dermitzakis, E. T., Devine, S. E., Kang, H. M., Kidd, J. M., Blackwell, T., Caron, S., Chen, W., Emery, S., Fritsche, L., Fuchsberger, C., Jun, G., Li, B., Lyons, R., Scheller, C., Sidore, C., Song, S., Sliwerska, E., Taliun, D., Tan, A., Welch, R., Wing, M. K., Zhan, X., Awadalla, P., Hodgkinson, A., Li, Y., Shi, X., Quitadamo, A., Lunter, G., Marchini, J. L., Myers, S., Churchhouse, C., Delaneau, O., Gupta-Hinch, A., Kretzschmar, W., Iqbal, Z., Mathieson, I., Menelaou, A., Rimmer, A., Xifara, D. K., Oleksyk, T. K., Fu, Y., Liu, X., Xiong, M., Jorde, L., Witherspoon, D., Xing, J., Browning, B. L., Browning, S. R., Hormozdiari, F., Sudmant, P. H., Khurana, E., Tyler-Smith, C., Albers, C. A., Ayub, Q., Chen, Y., Colonna, V., Jostins, L., Walter, K., Xue, Y., Gerstein, M. B., Abyzov, A., Balasubramanian, S., Chen, J., Clarke, D., Fu, Y., Harmanci, A. O., Jin, M., Lee, D., Liu, J., Mu, X. J., Zhang, J., Zhang, Y., Hartl, C., Shakir, K., Degenhardt, J., Meiers, S., Raeder, B., Casale, F. P., Stegle, O., Lameijer, E. W., Hall, I., Bafna, V., Michaelson, J., Gardner, E. J., Mills, R. E., Dayama, G., Chen, K., Fan, X., Chong, Z., Chen, T., Chaisson, M. J., Huddleston, J., Malig, M., Nelson, B. J., Parrish, N. F., Blackburne, B., Lindsay, S. J., Ning, Z., Zhang, Y., Lam, H., Sisu, C., Challis, D., Evani, U. S., Lu, J., Nagaswamy, U., Yu, J., Li, W., Habegger, L., Yu, H., Cunningham, F., Dunham, I., Lage, K., Jespersen, J. B., Horn, H., Kim, D., Desalle, R., Narechania, A., Sayres, M. A. W., Mendez, F. L., Poznik, G. D., Underhill, P. A., Mittelman, D., Banerjee, R., Cerezo, M., Fitzgerald, T. W., Louzada, S., Massaia, A., Yang, F., Kalra, D., Hale, W., Dan, X., Barnes, K. C., Beiswanger, C., Cai, H., Cao, H., Henn, B., Jones, D., Kaye, J. S., Kent, A., Kerasidou, A., Mathias, R., Ossorio, P. N., Parker, M., Rotimi, C. N., Royal, C. D., Sandoval, K., Su, Y., Tian, Z., Tishkoff, S., Via, M., Wang, Y., Yang, H., Yang, L., Zhu, J., Bodmer, W., Bedoya, G., Cai, Z., Gao, Y., Chu, J., Peltonen, L., Garcia-Montero, A., Orfao, A., Dutil, J., Martinez-Cruzado, J. C., Mathias, R. A., Hennis, A., Watson, H., McKenzie, C., Qadri, F., LaRocque, R., Deng, X., Asogun, D., Folarin, O., Happi, C., Omoniwa, O., Stremlau, M., Tariyal, R., Jallow, M., Joof, F. S., Corrah, T., Rockett, K., Kwiatkowski, D., Kooner, J., Hien, T. T., Dunstan, S. J., ThuyHang, N., Fonnie, R., Garry, R., Kanneh, L., Moses, L., Schieffelin, J., Grant, D. S., Gallo, C., Poletti, G., Saleheen, D., Rasheed, A., Brooks, L. D., Felsenfeld, A. L., McEwen, J. E., Vaydylevich, Y., Duncanson, A., Dunn, M. & Schloss, J. A., Sep 30 2015, In: Nature. 526, 7571, p. 68-74 7 p.

      Research output: Contribution to journal › Review article › peer-review

      Open Access
      10920 Scopus citations
    • 2014

      Expanding the computational toolbox for mining cancer genomes

      Ding, L., Wendl, M. C., McMichael, J. F. & Raphael, B. J., Aug 2014, In: Nature Reviews Genetics. 15, 8, p. 556-570 15 p.

      Research output: Contribution to journal › Review article › peer-review

      Open Access
      144 Scopus citations
    • 2013

      Advances for studying clonal evolution in cancer

      Ding, L., Raphael, B. J., Chen, F. & Wendl, M. C., Nov 1 2013, In: Cancer Letters. 340, 2, p. 212-219 8 p.

      Research output: Contribution to journal › Review article › peer-review

      Open Access
      55 Scopus citations

    • Computational approaches to identify functional genetic variants in cancer genomes

      Gonzalez-Perez, A., Mustonen, V., Reva, B., Ritchie, G. R. S., Creixell, P., Karchin, R., Vazquez, M., Fink, J. L., Kassahn, K. S., Pearson, J. V., Bader, G. D., Boutros, P. C., Muthuswamy, L., Ouellette, B. F. F., Reimand, J., Linding, R., Shibata, T., Valencia, A., Butler, A. & Dronov, S. & 8 others, Flicek, P., Shannon, N. B., Carter, H., Li, D., Sander, C., Stuart, J. M., Stein, L. D. & Lopez-Bigas, N., Aug 2013, In: Nature Methods. 10, 8, p. 723-729 7 p.

      Research output: Contribution to journal › Review article › peer-review

      134 Scopus citations
    • 2012

      The pediatric cancer genome project

      Downing, J. R., Wilson, R. K., Zhang, J., Mardis, E. R., Pui, C. H., Ding, L., Ley, T. J. & Evans, W. E., Jun 2012, In: Nature Genetics. 44, 6, p. 619-622 4 p.

      Research output: Contribution to journal › Review article › peer-review

      282 Scopus citations
    • 2010

      Challenges of sequencing human genomes

      Koboldt, D. C., Ding, L., Mardis, E. R. & Wilson, R. K., Sep 20 2010, In: Briefings in Bioinformatics. 11, 5, p. 484-498 15 p., bbq016.

      Research output: Contribution to journal › Review article › peer-review

      Open Access
      118 Scopus citations