Research output per year
Research output per year
- 1 - 50 out of 301 results
Search results
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2024
An HTLV-1 envelope mRNA vaccine is immunogenic and protective in New Zealand rabbits
Tu, J. J., King, E., Maksimova, V., Smith, S., Macias, R., Cheng, X., Vegesna, T., Yu, L., Ratner, L., Green, P. L., Niewiesk, S., Richner, J. M. & Panfil, A. R., Feb 2024, In: Journal of virology. 98, 2Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Assessment of the safety of nivolumab in people living with HIV with advanced cancer on antiretroviral therapy: the AIDS Malignancy Consortium 095 Study
Rajdev, L., Jackie Wang, C. C., Joshi, H., Lensing, S., Lee, J., Ramos, J. C., Baiocchi, R., Ratner, L., Rubinstein, P. G., Ambinder, R., Henry, D., Streicher, H., Little, R. F., Chiao, E., Dittmer, D. P., Einstein, M. H., Cesarman, E., Mitsuyasu, R. & Sparano, J. A., Mar 15 2024, In: Cancer. 130, 6, p. 985-994 10 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
2023
Brentuximab vedotin with AVD for stage II–IV HIV-related Hodgkin lymphoma (AMC 085): phase 2 results from an open-label, single arm, multicentre phase 1/2 trial
AIDS Malignancy Consortium & Lymphoma Study Association, Aug 2023, In: The Lancet Haematology. 10, 8, p. e624-e632Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Clinical characteristics and outcomes of infection with human T-lymphotropic virus in a non-endemic area: a single institution study
Gang, M., Gao, F., Poondru, S., Thomas, T. & Ratner, L., 2023, In: Frontiers in Microbiology. 14, 1187697.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Genetic subgroups inform on pathobiology in adult and pediatric Burkitt lymphoma
Thomas, N., Dreval, K., Gerhard, D. S., Hilton, L. K., Abramson, J. S., Ambinder, R. F., Barta, S., Bartlett, N. L., Bethony, J., Bhatia, K., Bowen, J., Bryan, A. C., Cesarman, E., Casper, C., Chadburn, A., Cruz, M., Dittmer, D. P., Dyer, M. A., Farinha, P. & Gastier-Foster, J. M. & 48 others, , Feb 23 2023, In: Blood. 141, 8, p. 904-916 13 p.Research output: Contribution to journal › Article › peer-review
Open Access28 Scopus citations -
Phase I Trial of the Multi-kinase Inhibitor Cabozantinib, a CYP3A4 Substrate, plus CYP3A4-Interacting Antiretroviral Therapy in People Living with HIV and Cancer (AMC-087)
Haigentz, M., Lee, J. Y., Chiao, E. Y., Aboulafia, D. M., Ratner, L., Ambinder, R. F., Baiocchi, R. A., Mitsuyasu, R. T., Wachsman, W., Sparano, J. A. & Rudek, M. A., Dec 15 2023, In: Clinical Cancer Research. 29, 24, p. 5038-5046 9 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
2022
Adult T-Cell Leukemia-Lymphoma Presenting Concurrently with Myelopathy
Poondru, S., Joseph, A., Harding, J. C., Sundaramoorthi, H., Mehta-Shah, N., Green, P., Hassan, A., Rauch, D. A. & Ratner, L., Nov 8 2022, In: Case Reports in Oncology. 15, 3, p. 918-926 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
A role for an HTLV-1 vaccine?
Ratner, L., Sep 8 2022, In: Frontiers in immunology. 13, 953650.Research output: Contribution to journal › Review article › peer-review
Open Access11 Scopus citations -
Defactinib, Pembrolizumab, and Gemcitabine in Patients with Advanced Treatment Refractory Pancreatic Cancer: A Phase I Dose Escalation and Expansion Study
Wang-Gillam, A., Lim, K. H., McWilliams, R., Suresh, R., Lockhart, A. C., Brown, A., Breden, M., Belle, J. I., Herndon, J., Bogner, S. J., Pedersen, K., Tan, B., Boice, N., Acharya, A., Abdiannia, M., Gao, F., Yoon, H. H., Zhu, M., Trikalinos, N. A. & Ratner, L. & 4 others, , Dec 15 2022, In: Clinical cancer research : an official journal of the American Association for Cancer Research. 28, 24, p. 5254-5262 9 p.Research output: Contribution to journal › Article › peer-review
Open Access40 Scopus citations -
Epigenetic regulation of human t‐cell leukemia virus gene expression
Ratner, L., Jan 2022, In: Microorganisms. 10, 1, 84.Research output: Contribution to journal › Review article › peer-review
Open Access3 Scopus citations -
Evolution of Multiple Domains of the HIV-1 Envelope Glycoprotein during Coreceptor Switch with CCR5 Antagonist Therapy
Du, Y., Wu, E., Gao, X., Zhang, J., Martin, J. C., Rosa, B. A., Mitreva, M. & Ratner, L., Aug 2022, In: Microbiology spectrum. 10, 4Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Heparanase Blockade as a Novel Dual-Targeting Therapy for COVID-19
Xiang, J., Lu, M., Shi, M., Cheng, X., Kwakwa, K. A., Davis, J. L., Su, X., Bakewell, S. J., Zhang, Y., Fontana, F., Xu, Y., Veis, D. J., DiPersio, J. F., Ratner, L., Sanderson, R. D., Noseda, A., Mollah, S., Li, J. & Weilbaecher, K. N., Apr 2022, In: Journal of virology. 96, 7, e00057-22.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
Phase 1b trial of anti-VEGF/PDGFR vorolanib combined with immune checkpoint inhibitors in patients with advanced solid tumors
Bagegni, N. A., Park, H., Kraft, K., O-Toole, M., Gao, F., Waqar, S. N., Ratner, L., Morgensztern, D., Devarakonda, S., Amin, M., Baggstrom, M. Q., Liang, C., Selvaggi, G. & Wang-Gillam, A., Apr 2022, In: Cancer Chemotherapy and Pharmacology. 89, 4, p. 487-497 11 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Safety and Tolerability of Carboplatin and Paclitaxel in Cancer Patients with HIV (AMC-078), an AIDS Malignancy Consortium (AMC) Study
Haigentz, M., Moore, P., Bimali, M., Cooley, T., Sparano, J., Rudek, M., Ratner, L., Henry, D., Ramos, J., Deeken, J., Rubinstein, P. & Chiao, E., Aug 1 2022, In: Oncologist. 27, 8, p. E623-E624Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
The Past, Present, and Future of a Human T-Cell Leukemia Virus Type 1 Vaccine
Tu, J. J., Maksimova, V., Ratner, L. & Panfil, A. R., May 4 2022, In: Frontiers in Microbiology. 13, 897346.Research output: Contribution to journal › Review article › peer-review
Open Access9 Scopus citations -
2021
Epigenomic regulation of human T-cell leukemia virus by chromatin-insulator CTCF
Cheng, X., Joseph, A., Castro, V., Chen-Liaw, A., Skidmore, Z., Payton, J. E., Ratner, L., Edwards, J. R., Ueno, T., Fujisawa, J. I., Rauch, D. A., Challen, G. A., Martinez, M. P., Green, P. & Griffith, M., May 2021, In: PLoS pathogens. 17, 5, e1009577.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Germinal epimutation of Fragile Histidine Triad (FHIT) gene is associated with progression to acute and chronic adult T-cell leukemia diseases
Bellon, M., Bialuk, I., Galli, V., Bai, X. T., Farre, L., Bittencourt, A., Marçais, A., Petrus, M. N., Ratner, L., Waldmann, T. A., Asnafi, V., Gessain, A., Matsuoka, M., Franchini, G., Hermine, O., Watanabe, T. & Nicot, C., Dec 2021, In: Molecular Cancer. 20, 1, 86.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Response-adapted therapy with infusional EPOCH chemotherapy plus rituximab in human immunodeficiency virus-associated, B-cell non-Hodgkin lymphoma
Sparano, J. A., Lee, J. Y., Kaplan, L. D., Ramos, J. C., Ambinder, R. F., Wachsman, W., Aboulafia, D., Noy, A., Henry, D. H., Ratner, L., Cesarman, E., Chadburn, A. & Mitsuyasu, R., Mar 2021, In: Haematologica. 106, 3, p. 730-735 6 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Targeting nf-κb with nanotherapy in a mouse model of adult t-cell leukemia/lymphoma
Rauch, D. A., Harding, J. C., Ratner, L., Wickline, S. A. & Pan, H., Jun 2021, In: Nanomaterials. 11, 6, 1582.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
2020
Impact of Myc in HIV-associated non-Hodgkin lymphomas treated with EPOCH and outcomes with vorinostat (AMC-075 trial)
for the AIDS Malignancy Consortium, Sep 10 2020, In: Blood. 136, 11, p. 1284-1297 14 p.Research output: Contribution to journal › Article › peer-review
Open Access41 Scopus citations -
Interferon regulatory factor 4 as a therapeutic target in adult T-cell leukemia lymphoma
Rauch, D. A., Olson, S. L., Harding, J. C., Sundaramoorthi, H., Kim, Y., Zhou, T., MacLeod, A. R., Challen, G. & Ratner, L., Aug 28 2020, In: Retrovirology. 17, 1, 27.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Molecular biology of human T cell leukemia virus
Ratner, L., Mar 2020, In: Seminars in Diagnostic Pathology. 37, 2, p. 104-109 6 p.Research output: Contribution to journal › Review article › peer-review
13 Scopus citations -
Predicting the future: Adult T-cell leukemia
Ratner, L., Jun 4 2020, In: Blood. 135, 23, p. 2013-2014 2 p.Research output: Contribution to journal › Review article › peer-review
Open Access2 Scopus citations -
The dual-specificity kinase DYRK1A modulates the levels of cyclin L2 to control HIV replication in macrophages
Kisaka, J. K., Ratner, L. & Kyei, G. B., Mar 1 2020, In: Journal of virology. 94, 6, e01583-19.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
2019
AIDS-related Kaposi sarcoma, version 2.2019
Reid, E., Suneja, G., Ambinder, R. F., Ard, K., Baiocchi, R., Barta, S. K., Carchman, E., Cohen, A., Crysler, O. V., Gupta, N., Gustafson, C., Hall, A., Johung, K. L., Klopp, A., LaCasce, A. S., Lin, C., Mehta, A., Menon, M. P., Morgan, D. & Nathwani, N. & 11 others, , Feb 2019, In: JNCCN Journal of the National Comprehensive Cancer Network. 17, 2, p. 171-189 19 p.Research output: Contribution to journal › Article › peer-review
Open Access29 Scopus citations -
Biomarkers and Preclinical Models for Adult T-Cell Leukemia-Lymphoma Treatment
Ratner, L., Sep 18 2019, In: Frontiers in Microbiology. 10, 2109.Research output: Contribution to journal › Review article › peer-review
Open Access1 Scopus citations -
Dynamic host immune response in virus-associated cancers
Cao, S., Wylie, K. M., Wyczalkowski, M. A., Karpova, A., Ley, J., Sun, S., Mashl, R. J., Liang, W. W., Wang, X., Johnson, K., DiPersio, J. F., Gay, H., Ratner, L., Chen, F., Adkins, D. R. & Ding, L., Dec 1 2019, In: Communications Biology. 2, 1, 109.Research output: Contribution to journal › Article › peer-review
Open Access37 Scopus citations -
HTLV-1 CTCF-binding site is dispensable for in vitro immortalization and persistent infection in vivo
Martinez, M. P., Cheng, X., Joseph, A., Al-Saleem, J., Panfil, A. R., Palettas, M., Dirksen, W. P., Ratner, L. & Green, P. L., Dec 21 2019, In: Retrovirology. 16, 1, 44.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
HTLV-1 Tax-1 interacts with SNX27 to regulate cellular localization of the HTLV-1 receptor molecule, GLUT1
Al-Saleem, J., Dirksen, W. P., Martinez, M. P., Shkriabai, N., Kvaratskhelia, M., Ratner, L. & Green, P. L., Mar 2019, In: PloS one. 14, 3, e0214059.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
HTLV-1 viral oncogene HBZ drives bone destruction in adult T cell leukemia
Xiang, J., Rauch, D. A., Huey, D. D., Panfil, A. R., Cheng, X., Esser, A. K., Su, X., Harding, J. C., Xu, Y., Fox, G. C., Fontana, F., Kobayashi, T., Su, J., Sundaramoorthi, H., Wong, W. H., Jia, Y., Rosol, T. J., Veis, D. J., Green, P. L. & Niewiesk, S. & 2 others, , 2019, In: JCI Insight. 4, 19, e128713.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Rapid progression of adult T-cell leukemia/lymphoma as tumor-infiltrating Tregs after PD-1 blockade
Rauch, D. A., Conlon, K. C., Janakiram, M., Brammer, J. E., Harding, J. C., Ye, B. H., Zang, X., Ren, X., Olson, S., Cheng, X., Miljkovic, M. D., Sundaramoorthi, H., Joseph, A., Skidmore, Z. L., Griffith, O., Griffith, M., Waldmann, T. A. & Ratner, L., Oct 24 2019, In: Blood. 134, 17, p. 1406-1414 9 p.Research output: Contribution to journal › Article › peer-review
Open Access85 Scopus citations -
Revised adult T-cell leukemia-lymphoma international consensus meeting report
Cook, L. B., Fuji, S., Hermine, O., Bazarbachi, A., Ramos, J. C., Ratner, L., Horwitz, S., Fields, P., Tanase, A., Bumbea, H., Cwynarski, K., Taylor, G., Waldmann, T. A., Bittencourt, A., Marcais, A., Suarez, F., Sibon, D., Phillips, A., Lunning, M. & Farid, R. & 12 others, , Mar 10 2019, In: Journal of Clinical Oncology. 37, 8, p. 677-687 11 p.Research output: Contribution to journal › Article › peer-review
Open Access170 Scopus citations -
The human T-cell leukemia virus type-1 tax oncoprotein dissociates NF-κB p65RelA-Stathmin complexes and causes catastrophic mitotic spindle damage and genomic instability
Malu, A., Hutchison, T., Yapindi, L., Smith, K., Nelson, K., Bergeson, R., Pope, J., Romeo, M., Harrod, C., Ratner, L., Van Lint, C. & Harrod, R., Sep 2019, In: Virology. 535, p. 83-101 19 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
V1 and V2 domains of HIV envelope contribute to CCR5 antagonist resistance
Wu, E., Du, Y., Gao, X., Zhang, J., Martin, J., Mitreva, M. & Ratner, L., May 1 2019, In: Journal of virology. 93, 9, e00050-19.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
2018
An activating mutation of interferon regulatory factor 4 (IRF4) in adult T-cell leukemia
Cherian, M. A., Olson, S., Sundaramoorthi, H., Cates, K., Cheng, X., Harding, J., Martens, A., Challen, G. A., Tyagi, M., Ratner, L. & Rauch, D., May 4 2018, In: Journal of Biological Chemistry. 293, 18, p. 6844-6858 15 p.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
Brentuximab vedotin with AVD shows safety, in the absence of strong CYP3A4 inhibitors, in newly diagnosed HIV-associated Hodgkin lymphoma
Rubinstein, P. G., Moore, P. C., Rudek, M. A., Henry, D. H., Ramos, J. C., Ratner, L., Reid, E., Sharon, E. & Noy, A., Mar 13 2018, In: AIDS. 32, 5, p. 605-611 7 p.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
Cancer in people living with HIV, version 1.2018: Clinical practice guidelines in oncology
Reid, E., Suneja, G., Ambinder, R. F., Ard, K., Baiocchi, R., Barta, S. K., Carchman, E., Cohen, A., Gupta, N., Johung, K. L., Klopp, A., LaCasce, A. S., Lin, C., Makarova-Rusher, O. V., Mehta, A., Menon, M. P., Morgan, D., Nathwani, N., Noy, A. & Palella, F. & 8 others, , Aug 1 2018, In: JNCCN Journal of the National Comprehensive Cancer Network. 16, 8, p. 986-1017 32 p.Research output: Contribution to journal › Review article › peer-review
Open Access70 Scopus citations -
HIV-Infected Young Men Demonstrate Appropriate Risk Perceptions and Beliefs about Safer Sexual Behaviors after Human Papillomavirus Vaccination
For the AIDS Malignancy Consortium and Adolescent Medicine Trials Network for HIV/AIDS Interventions, Jun 1 2018, In: AIDS and Behavior. 22, 6, p. 1826-1834 9 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
North American ATLL has a distinct mutational and transcriptional profile and responds to epigenetic therapies
Shah, U. A., Chung, E. Y., Giricz, O., Pradhan, K., Kataoka, K., Gordon-Mitchel, S., Bhagat, T. D., Mai, Y., Wei, Y., Ishida, E., Choudhary, G. S., Joseph, A., Rice, R., Gitego, N., Parrish, C., Bartenstein, M., Goel, S., Mantzaris, I., Shastri, A. & Derman, O. & 13 others, , Oct 4 2018, In: Blood. 132, 14, p. 1507-1518 12 p.Research output: Contribution to journal › Article › peer-review
Open Access64 Scopus citations -
Oncogenic viruses
Buck, C. B., Ratner, L. & Tosato, G., Nov 16 2018, DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology. Wolters Kluwer Health Pharma Solutions (Europe) Ltd, p. 99-114 16 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
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PDZ domain-binding motif of Tax sustains T-cell proliferation in HTLV-1-infected humanized mice
Pérès, E., Blin, J., Ricci, E. P., Artesi, M., Hahaut, V., Van den Broeke, A., Corbin, A., Gazzolo, L., Ratner, L., Jalinot, P. & Duc Dodon, M., Mar 2018, In: PLoS pathogens. 14, 3, e1006933.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
Rapid progression of adult T-cell leukemia–lymphoma after PD-1 inhibitor therapy
Ratner, L., Waldmann, T. A., Janakiram, M. & Brammer, J. E., May 17 2018, In: New England Journal of Medicine. 378, 20, p. 1947-1948 2 p.Research output: Contribution to journal › Letter › peer-review
182 Scopus citations -
Role of wild-type and recombinant human T-cell leukemia viruses in lymphoproliferative disease in humanized NSG mice
Huey, D. D., Bolon, B., La Perle, K. M. D., Kannian, P., Jacobson, S., Ratner, L., Green, P. L. & Niewiesk, S., Feb 2018, In: Comparative medicine. 68, 1, p. 4-14 11 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
Safety and Preliminary Efficacy of Vorinostat With R-EPOCH in High-risk HIV-associated Non-Hodgkin's Lymphoma (AMC-075)
Ramos, J. C., Sparano, J. A., Rudek, M. A., Moore, P. C., Cesarman, E., Reid, E. G., Henry, D., Ratner, L., Aboulafia, D., Lee, J. Y., Ambinder, R. F., Mitsuyasu, R. & Noy, A., Mar 2018, In: Clinical Lymphoma, Myeloma and Leukemia. 18, 3, p. 180-190.e2Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Splicing factor 3B subunit 1 interacts with HIV tat and plays a role in viral transcription and reactivation from latency
Kyei, G. B., Meng, S., Ramani, R., Niu, A., Lagisetti, C., Webb, T. R. & Ratner, L., Nov 1 2018, In: mBio. 9, 6, e01423-18.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
The human T-cell leukemia virus type-1 p30II protein activates p53 and induces the TIGAR and suppresses oncogene-induced oxidative stress during viral carcinogenesis
Romeo, M., Hutchison, T., Malu, A., White, A., Kim, J., Gardner, R., Smith, K., Nelson, K., Bergeson, R., McKee, R., Harrod, C., Ratner, L., Lüscher, B., Martinez, E. & Harrod, R., May 2018, In: Virology. 518, p. 103-115 13 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
The TP53-Induced Glycolysis and Apoptosis Regulator mediates cooperation between HTLV-1 p30II and the retroviral oncoproteins Tax and HBZ and is highly expressed in an in vivo xenograft model of HTLV-1-induced lymphoma
Hutchison, T., Malu, A., Yapindi, L., Bergeson, R., Peck, K., Romeo, M., Harrod, C., Pope, J., Smitherman, L., Gwinn, W., Ratner, L., Yates, C. & Harrod, R., Jul 2018, In: Virology. 520, p. 39-58 20 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
2017
Adult T-cell leukemia/lymphoma
Mehta-Shah, N., Ratner, L. & Horwitz, S. M., Aug 1 2017, In: Journal of Oncology Practice. 13, 8, p. 487-492 6 p.Research output: Contribution to journal › Review article › peer-review
Open Access51 Scopus citations -
Cetuximab plus chemoradiotherapy for HIV-associated anal carcinoma: A phase II AIDS malignancy consortium trial
Sparano, J. A., Lee, J. Y., Palefsky, J., Henry, D. H., Wachsman, W., Rajdev, L., Aboulafia, D., Ratner, L., Fitzgerald, T. J., Kachnic, L. & Mitsuyasu, R., Mar 1 2017, In: Journal of Clinical Oncology. 35, 7, p. 727-733 7 p.Research output: Contribution to journal › Article › peer-review
Open Access61 Scopus citations -
Combinations of isoform-targeted histone deacetylase inhibitors and bryostatin analogues display remarkable potency to activate latent HIV without global T-cell activation
Albert, B. J., Niu, A., Ramani, R., Marshall, G. R., Wender, P. A., Williams, R. M., Ratner, L., Barnes, A. B. & Kyei, G. B., Dec 1 2017, In: Scientific reports. 7, 1, 7456.Research output: Contribution to journal › Article › peer-review
Open Access35 Scopus citations