Laura Ibanez

2024

Comparison of tau spread in people with Down syndrome versus autosomal-dominant Alzheimer's disease: a cross-sectional study

Alzheimer's Biomarker Consortium–Down Syndrome, Dominantly Inherited Alzheimer Network, Wisch, J. K., McKay, N. S., Boerwinkle, A. H., Kennedy, J., Flores, S., Handen, B. L., Christian, B. T., Head, E., Mapstone, M., Rafii, M. S., O'Bryant, S. E., Price, J. C., Laymon, C. M., Krinsky-McHale, S. J., Lai, F., Rosas, H. D., Hartley, S. L. & Zaman, S. & 152 others, Lott, I. T., Tudorascu, D., Zammit, M., Brickman, A. M., Lee, J. H., Bird, T. D., Cohen, A., Chrem, P., Daniels, A., Chhatwal, J. P., Cruchaga, C., Ibanez, L., Jucker, M., Karch, C. M., Day, G. S., Lee, J. H., Levin, J., Llibre-Guerra, J., Li, Y., Lopera, F., Roh, J. H., Ringman, J. M., Supnet-Bell, C., van Dyck, C. H., Xiong, C., Wang, G., Morris, J. C., McDade, E., Bateman, R. J., Benzinger, T. L. S., Gordon, B. A., Ances, B. M., Aizenstein, H. J., Andrews, H. F., Bell, K., Birn, R. M., Bulova, P., Cheema, A., Chen, K., Clare, I., Clark, L., Cohen, A. D., Constantino, J. N., Doran, E. W., Feingold, E., Foroud, T. M., Hartley, S. L., Hom, C., Honig, L., Ikonomovic, M. D., Johnson, S. C., Jordan, C., Kamboh, M. I., Keator, D., Klunk, W. E., Kofler, J. K., Kreisl, W. C., Krinsky-McHale, S. J., Lao, P., Laymon, C., Lott, I. T., Lupson, V., Mathis, C. A., Minhas, D. S., Nadkarni, N., Pang, D., Petersen, M., Price, J. C., Pulsifer, M., Reiman, E., Rizvi, B., Sabbagh, M. N., Schupf, N., Tudorascu, D. L., Tumuluru, R., Tycko, B., Varadarajan, B., White, D. A., Yassa, M. A., Zhang, F., Bateman, R., Daniels, A., Courtney, L., Llibre-Guerra, J., Xiong, C., Xu, X., Lu, R., Gremminger, E., Perrin, R. J., Franklin, E., Jerome, G., Herries, E., Stauber, J., Baker, B., Minton, M., Goate, A. M., Renton, A. E., Picarello, D. M., Benzinger, T., Gordon, B. A., Hornbeck, R., Hassenstab, J., Smith, J., Stout, S., Aschenbrenner, A. J., Karch, C. M., Marsh, J., Morris, J. C., Holtzman, D. M., Barthelemy, N., Xu, J., Noble, J. M., Berman, S. B., Ikonomovic, S., Nadkarni, N. K., Day, G., Graff-Radford, N. R., Farlow, M., Chhatwal, J. P., Ikeuchi, T., Kasuga, K., Niimi, Y., Huey, E. D., Salloway, S., Schofield, P. R., Brooks, W. S., Bechara, J. A., Martins, R., Fox, N. C., Cash, D. M., Ryan, N. S., Laske, C., Hofmann, A., Kuder-Buletta, E., Graber-Sultan, S., Obermueller, U., Roedenbeck, Y., Vöglein, J., Sanchez-Valle, R., Rosa-Neto, P., Allegri, R. F., Chrem Mendez, P., Surace, E., Vazquez, S., Leon, Y. M., Ramirez, L., Aguillon, D., Levey, A. I., Johnson, E. C. B., Seyfried, N. T., Ringman, J. & Mori, H., May 2024, In: The Lancet Neurology. 23, 5, p. 500-510 11 p.

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Downstream Biomarker Effects of Gantenerumab or Solanezumab in Dominantly Inherited Alzheimer Disease: The DIAN-TU-001 Randomized Clinical Trial

Wagemann, O., Liu, H., Wang, G., Shi, X., Bittner, T., Scelsi, M. A., Farlow, M. R., Clifford, D. B., Supnet-Bell, C., Santacruz, A. M., Aschenbrenner, A. J., Hassenstab, J. J., Benzinger, T. L. S., Gordon, B. A., Coalier, K. A., Cruchaga, C., Ibanez, L., Perrin, R. J., Xiong, C. & Li, Y. & 30 others, Morris, J. C., Lah, J. J., Berman, S. B., Roberson, E. D., Van Dyck, C. H., Galasko, D., Gauthier, S., Hsiung, G. Y. R., Brooks, W. S., Pariente, J., Mummery, C. J., Day, G. S., Ringman, J. M., Mendez, P. C., St. George-Hyslop, P., Fox, N. C., Suzuki, K., Okhravi, H. R., Chhatwal, J., Levin, J., Jucker, M., Sims, J. R., Holdridge, K. C., Proctor, N. K., Yaari, R., Andersen, S. W., Mancini, M., Llibre-Guerra, J., Bateman, R. J. & McDade, E., Jun 10 2024, In: JAMA Neurology. 81, 6, p. 582-593 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Genetic and multi-omic resources for Alzheimer disease and related dementia from the Knight Alzheimer Disease Research Center

Fernandez, M. V., Liu, M., Beric, A., Johnson, M., Cetin, A., Patel, M., Budde, J., Kohlfeld, P., Bergmann, K., Lowery, J., Flynn, A., Brock, W., Sanchez Montejo, B., Gentsch, J., Sykora, N., Norton, J., Gentsch, J., Valdez, O., Gorijala, P. & Sanford, J. & 24 others, Sun, Y., Wang, C., Western, D., Timsina, J., Mangetti Goncalves, T., Do, A. N., Sung, Y. J., Zhao, G., Morris, J. C., Moulder, K., Holtzman, D. M., Bateman, R. J., Karch, C., Hassenstab, J., Xiong, C., Schindler, S. E., Balls-Berry, J., Benzinger, T. L. S., Perrin, R. J., Denny, A., Snider, B. J., Stark, S. L., Ibanez, L. & Cruchaga, C., Dec 2024, In: Scientific data. 11, 1, 768.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Multi-ancestry genome-wide association meta-analysis of Parkinson’s disease

Kim, J. J., Vitale, D., Otani, D. V., Lian, M. M., Heilbron, K., Aslibekyan, S., Auton, A., Babalola, E., Bell, R. K., Bielenberg, J., Bryc, K., Bullis, E., Cannon, P., Coker, D., Partida, G. C., Dhamija, D., Das, S., Elson, S. L., Eriksson, N. & Filshtein, T. & 279 others, Fitch, A., Fletez-Brant, K., Fontanillas, P., Freyman, W., Granka, J. M., Hernandez, A., Hicks, B., Hinds, D. A., Jewett, E. M., Jiang, Y., Kukar, K., Kwong, A., Lin, K. H., Llamas, B. A., Lowe, M., McCreight, J. C., McIntyre, M. H., Micheletti, S. J., Moreno, M. E., Nandakumar, P., Nguyen, D. T., Noblin, E. S., O’Connell, J., Petrakovitz, A. A., Poznik, G. D., Reynoso, A., Schloetter, M., Schumacher, M., Shastri, A. J., Shelton, J. F., Shi, J., Shringarpure, S., Su, Q. J., Tat, S. A., Tchakouté, C. T., Tran, V., Tung, J. Y., Wang, X., Wang, W., Weldon, C. H., Wilton, P., Wong, C. D., Iwaki, H., Lake, J., Solsberg, C. W., Leonard, H., Makarious, M. B., Tan, E. K., Singleton, A. B., Bandres-Ciga, S., Noyce, A. J., Gatto, E. M., Kauffman, M., Khachatryan, S., Tavadyan, Z., Shepherd, C. E., Hunter, J., Kumar, K., Ellis, M., Rentería, M. E., Koks, S., Zimprich, A., Schumacher-Schuh, A. F., Rieder, C., Awad, P. S., Tumas, V., Camargos, S., Fon, E. A., Monchi, O., Fon, T., Galleguillos, B. P., Miranda, M., Bustamante, M. L., Olguin, P., Chana, P., Tang, B., Shang, H., Guo, J., Chan, P., Luo, W., Arboleda, G., Orozc, J., del Rio, M. J., Hernandez, A., Salama, M., Kamel, W. A., Zewde, Y. Z., Brice, A., Corvol, J. C., Westenberger, A., Illarionova, A., Mollenhauer, B., Klein, C., Vollstedt, E. J., Hopfner, F., Höglinger, G., Madoev, H., Trinh, J., Junker, J., Lohmann, K., Lange, L. M., Sharma, M., Groppa, S., Gasser, T., Fang, Z. H., Akpalu, A., Xiromerisiou, G., Hadjigorgiou, G., Dagklis, I., Tarnanas, I., Stefanis, L., Stamelou, M., Dadiotis, E., Medina, A., Chan, G. H. F., Ip, N., Cheung, N. Y. F., Chan, P., Zhou, X., Kishore, A., Divya, K. P., Pal, P., Kukkle, P. L., Rajan, R., Borgohain, R., Salari, M., Quattrone, A., Valente, E. M., Parnetti, L., Avenali, M., Schirinzi, T., Funayama, M., Hattori, N., Shiraishi, T., Karimova, A., Kaishibayeva, G., Shambetova, C., Krüger, R., Tan, A. H., Ahmad-Annuar, A., Norlinah, M. I., Murad, N. A. A., Azmin, S., Lim, S. Y., Mohamed, W., Tay, Y. W., Martinez-Ramirez, D., Rodriguez-Violante, M., Reyes-Pérez, P., Tserensodnom, B., Ojha, R., Anderson, T. J., Pitcher, T. L., Sanyaolu, A., Okubadejo, N., Ojo, O., Aasly, J. O., Pihlstrøm, L., Tan, M., Ur-Rehman, S., Veliz-Otani, D., Cornejo-Olivas, M., Doquenia, M. L., Rosales, R., Vinuela, A., Iakovenko, E., Mubarak, B. A., Umair, M., Amod, F., Carr, J., Bardien, S., Jeon, B., Kim, Y. J., Cubo, E., Alvarez, I., Hoenicka, J., Beyer, K., Periñan, M. T., Pastor, P., El-Sadig, S., Brolin, K., Zweier, C., Tinkhauser, G., Krack, P., Lin, C. H., Wu, H. C., Kung, P. J., Wu, R. M., Wu, Y., Amouri, R., Sassi, S. B., Başak, A. N., Genc, G., Çakmak, Ö. Ö., Ertan, S., Martínez-Carrasco, A., Schrag, A., Schapira, A., Carroll, C., Bale, C., Grosset, D., Stafford, E. J., Houlden, H., Morris, H. R., Hardy, J., Mok, K. Y., Rizig, M., Wood, N., Williams, N., Okunoye, O., Lewis, P. A., Kaiyrzhanov, R., Weil, R., Love, S., Stott, S., Jasaityte, S., Dey, S., Obese, V., Espay, A., O’Grady, A., Sobering, A. K., Siddiqi, B., Casey, B., Fiske, B., Jonas, C., Cruchaga, C., Pantazis, C. B., Comart, C., Wegel, C., Hall, D., Hernandez, D., Shiamim, E., Riley, E., Faghri, F., Serrano, G. E., Chen, H., Mata, I. F., Sarmiento, I. J. K., Williamson, J., Jankovic, J., Shulman, J., Solle, J. C., Murphy, K., Nuytemans, K., Kieburtz, K., Markopoulou, K., Marek, K., Levine, K. S., Chahine, L. M., Ibanez, L., Screven, L., Ruffrage, L., Shulman, L., Marsili, L., Kuhl, M., Dean, M., Koretsky, M., Puckelwartz, M. J., Inca-Martinez, M., Louie, N., Mencacci, N. E., Albin, R., Alcalay, R., Walker, R., Chowdhury, S., Dumanis, S., Lubbe, S., Xie, T., Foroud, T., Beach, T., Sherer, T., Song, Y., Nguyen, D., Nguyen, T., Atadzhanov, M., Blauwendraat, C., Nalls, M. A., Foo, J. N. & Mata, I., Jan 2024, In: Nature Genetics. 56, 1, p. 27-36 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

22 Scopus citations

α-Synuclein seed amplification assay detects Lewy body co-pathology in autosomal dominant Alzheimer's disease late in the disease course and dependent on Lewy pathology burden

Dominantly Inherited Alzheimer Network, Levin, J., Baiardi, S., Quadalti, C., Rossi, M., Mammana, A., Vöglein, J., Bernhardt, A., Perrin, R. J., Jucker, M., Preische, O., Hofmann, A., Höglinger, G. U., Cairns, N. J., Franklin, E. E., Chrem, P., Cruchaga, C., Berman, S. B., Chhatwal, J. P. & Daniels, A. & 27 others, Day, G. S., Ryan, N. S., Goate, A. M., Gordon, B. A., Huey, E. D., Ibanez, L., Karch, C. M., Lee, J. H., Llibre-Guerra, J., Lopera, F., Masters, C. L., Morris, J. C., Noble, J. M., Renton, A. E., Roh, J. H., Frosch, M. P., Keene, C. D., McLean, C., Sanchez-Valle, R., Schofield, P. R., Supnet-Bell, C., Xiong, C., Giese, A., Hansson, O., Bateman, R. J., McDade, E. & Parchi, P., Jun 2024, In: Alzheimer's and Dementia. 20, 6, p. 4351-4365 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

2023

Advanced structural brain aging in preclinical autosomal dominant Alzheimer disease

Millar, P. R., Gordon, B. A., Wisch, J. K., Schultz, S. A., Benzinger, T. L., Cruchaga, C., Hassenstab, J. J., Ibanez, L., Karch, C., Llibre-Guerra, J. J., Morris, J. C., Perrin, R. J., Supnet-Bell, C., Xiong, C., Allegri, R. F., Berman, S. B., Chhatwal, J. P., Chrem Mendez, P. A., Day, G. S. & Hofmann, A. & 13 others, Ikeuchi, T., Jucker, M., Lee, J. H., Levin, J., Lopera, F., Niimi, Y., Sánchez-González, V. J., Schofield, P. R., Sosa-Ortiz, A. L., Vöglein, J., Bateman, R. J., Ances, B. M. & McDade, E. M., Dec 2023, In: Molecular neurodegeneration. 18, 1, 98.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Cell-free RNA signatures predict Alzheimer's disease

Cisterna-García, A., Beric, A., Ali, M., Pardo, J. A., Chen, H. H., Fernandez, M. V., Norton, J., Gentsch, J., Bergmann, K., Budde, J., Perlmutter, J. S., Morris, J. C., Cruchaga, C., Botia, J. A. & Ibanez, L., Dec 15 2023, In: iScience. 26, 12, 108534.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Defining the causes of sporadic Parkinson’s disease in the global Parkinson’s genetics program (GP2)

Towns, C., Richer, M., Jasaityte, S., Stafford, E. J., Joubert, J., Antar, T., Martinez-Carrasco, A., Makarious, M. B., Casey, B., Vitale, D., Levine, K., Leonard, H., Pantazis, C. B., Screven, L. A., Hernandez, D. G., Wegel, C. E., Solle, J., Nalls, M. A., Blauwendraat, C. & Singleton, A. B. & 224 others, Tan, M. M. X., Iwaki, H., Morris, H. R., Gatto, E. M., Kauffman, M., Khachatryan, S., Tavadyan, Z., Shepherd, C. E., Hunter, J., Kumar, K., Ellis, M., Rentería, M. E., Koks, S., Zimprich, A., Schumacher-Schuh, A. F., Rieder, C., Awad, P. S., Tumas, V., Camargos, S., Fon, E. A., Monchi, O., Fon, T., Galleguillos, B. P., Miranda, M., Bustamante, M. L., Olguin, P., Chana, P., Tang, B., Shang, H., Guo, J., Chan, P., Luo, W., Arboleda, G., Orozco, J., del Rio, M. J., Hernandez, A., Salama, M., Kamel, W. A., Zewde, Y. Z., Brice, A., Corvol, J. C., Westenberger, A., Illarionova, A., Mollenhauer, B., Klein, C., Vollstedt, E. J., Hopfner, F., Höglinger, G., Madoev, H., Trinh, J., Junker, J., Lohmann, K., Lange, L. M., Sharma, M., Groppa, S., Gasser, T., Fang, Z. H., Akpalu, A., Xiromerisiou, G., Hadjigorgiou, G., Dagklis, I., Tarnanas, I., Stefanis, L., Stamelou, M., Dadiotis, E., Medina, A., Chan, G. H. F., Ip, N., Cheung, N. Y. F., Chan, P., Zhou, X., Kishore, A., Kp, D., Pal, P., Kukkle, P. L., Rajan, R., Borgohain, R., Salari, M., Quattrone, A., Valente, E. M., Parnetti, L., Avenali, M., Schirinzi, T., Funayama, M., Hattori, N., Shiraishi, T., Karimova, A., Kaishibayeva, G., Shambetova, C., Krüger, R., Tan, A. H., Ahmad-Annuar, A., Norlinah, M. I., Murad, N. A. A., Azmin, S., Lim, S. Y., Mohamed, W., Tay, Y. W., Martinez-Ramirez, D., Rodriguez-Violante, M., Reyes-Pérez, P., Tserensodnom, B., Ojha, R., Anderson, T. J., Pitcher, T. L., Sanyaolu, A., Okubadejo, N., Ojo, O., Aasly, J. O., Pihlstrøm, L., Tan, M., Ur-Rehman, S., Cornejo-Olivas, M., Doquenia, M. L., Rosales, R., Vinuela, A., Iakovenko, E., Mubarak, B. A., Umair, M., Tan, E. K., Foo, J. N., Amod, F., Carr, J., Bardien, S., Jeon, B., Kim, Y. J., Cubo, E., Alvarez, I., Hoenicka, J., Beyer, K., Periñan, M. T., Pastor, P., El-Sadig, S., Zweier, C., Krack, P., Lin, C. H., Wu, H. C., Kung, P. J., Wu, R. M., Wu, Y., Amouri, R., Sassi, S. B., Başak, A. N., Genc, G., Çakmak, Ö. Ö., Ertan, S., Noyce, A., Schrag, A., Schapira, A., Carroll, C., Bale, C., Grosset, D., Houlden, H., Hardy, J., Mok, K. Y., Rizig, M., Wood, N., Williams, N., Okunoye, O., Lewis, P. A., Kaiyrzhanov, R., Weil, R., Love, S., Stott, S., Jasaitye, S., Dey, S., Obese, V., Espay, A., O’Grady, A., Sobering, A. K., Siddiqi, B., Fiske, B., Jonas, C., Cruchaga, C., Comart, C., Wegel, C., Hall, D., Hernandez, D., Shiamim, E., Riley, E., Faghri, F., Serrano, G. E., Chen, H., Mata, I. F., Sarmiento, I. J. K., Williamson, J., Kim, J. J., Jankovic, J., Shulman, J., Solle, J. C., Murphy, K., Nuytemans, K., Kieburtz, K., Markopoulou, K., Marek, K., Levine, K. S., Chahine, L. M., Ibanez, L., Screven, L., Ruffrage, L., Shulman, L., Marsili, L., Kuhl, M., Dean, M., Koretsky, M., Puckelwartz, M. J., Inca-Martinez, M., Louie, N., Mencacci, N. E., Albin, R., Alcalay, R., Walker, R., Bandres-Ciga, S., Chowdhury, S., Dumanis, S., Lubbe, S., Xie, T., Foroud, T., Beach, T., Sherer, T., Song, Y., Nguyen, D., Nguyen, T. & Atadzhanov, M., Dec 2023, In: npj Parkinson's Disease. 9, 1, 131.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Editorial: Molecular and cellular mechanisms of synaptopathies: emerging synaptic aging-related molecular pathways in neurological disorders

Quintá, H. R., Ibanez, L., Cruchaga, C. & Maschi, D., 2023, In: Frontiers in Aging Neuroscience. 15, 1267033.

Research output: Contribution to journal › Editorial

Open Access

Proteome wide association studies of LRRK2 variants identify novel causal and druggable proteins for Parkinson’s disease

Dominantly Inherited Alzheimer Network (DIAN) Consortia, Dec 2023, In: npj Parkinson's Disease. 9, 1, 107.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

2022

A Polygenic Risk Score Based on a Cardioembolic Stroke Multitrait Analysis Improves a Clinical Prediction Model for This Stroke Subtype

GeneStroke Consortium and International Stroke Genetics Consortium, Jul 8 2022, In: Frontiers in Cardiovascular Medicine. 9, 940696.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Circular RNA detection identifies circPSEN1 alterations in brain specific to autosomal dominant Alzheimer's disease

Dominantly Inherited Alzheimer Network, Dec 2022, In: Acta Neuropathologica Communications. 10, 1, 29.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Inhibition of the enzyme autotaxin reduces cortical excitability and ameliorates the outcome in stroke

Bitar, L., Uphaus, T., Thalman, C., Muthuraman, M., Gyr, L., Ji, H., Domingues, M., Endle, H., Groppa, S., Steffen, F., Koirala, N., Fan, W., Ibanez, L., Heitsch, L., Cruchaga, C., Lee, J. M., Kloss, F., Bittner, S., Nitsch, R. & Zipp, F. & 1 others, Vogt, J., Apr 20 2022, In: Science translational medicine. 14, 641, eabk0135.

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Multi-Ancestry GWAS reveals excitotoxicity associated with outcome after ischaemic stroke

Ibanez, L., Heitsch, L., Carrera, C., Farias, F. H. G., Del Aguila, J. L., Dhar, R., Budde, J., Bergmann, K., Bradley, J., Harari, O., Phuah, C. L., Lemmens, R., Souza, A. A. V. O., Moniche, F., Cabezas-Juan, A., Arenillas, J. F., Krupinksi, J., Cullell, N., Torres-Aguila, N. & Muiño, E. & 56 others, Cárcel-Márquez, J., Marti-Fabregas, J., Delgado-Mederos, R., Marin-Bueno, R., Hornick, A., Vives-Bauza, C., Navarro, R. D., Tur, S., Jimenez, C., Obach, V., Segura, T., Serrano-Heras, G., Chung, J. W., Roquer, J., Soriano-Tarraga, C., Giralt-Steinhauer, E., Mola-Caminal, M., Pera, J., Lapicka-Bodzioch, K., Derbisz, J., Davalos, A., Lopez-Cancio, E., Muñoz, L., Tatlisumak, T., Molina, C., Ribo, M., Bustamante, A., Sobrino, T., Castillo-Sanchez, J., Campos, F., Rodriguez-Castro, E., Arias-Rivas, S., Rodríguez-Yáñez, M., Herbosa, C., Ford, A. L., Gutierrez-Romero, A., Uribe-Pacheco, R., Arauz, A., Lopes-Cendes, I., Lowenkopf, T., Barboza, M. A., Amini, H., Stamova, B., Ander, B. P., Sharp, F. R., Moon Kim, G., Bang, O. Y., Jimenez-Conde, J., Slowik, A., Stribian, D., Tsai, E. A., Burkly, L. C., Montaner, J., Fernandez-Cadenas, I., Lee, J. M. & Cruchaga, C., Jul 1 2022, In: Brain. 145, 7, p. 2394-2406 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

Multi-phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations

Temprano-Sagrera, G., Sitlani, C. M., Bone, W. P., Martin-Bornez, M., Voight, B. F., Morrison, A. C., Damrauer, S. M., de Vries, P. S., Smith, N. L., Sabater-Lleal, M., Dehghan, A., Heath, A. S., Morrison, A. C., Reiner, A. P., Johnson, A., Richmond, A., Peters, A., van Hylckama Vlieg, A., McKnight, B. & Psaty, B. M. & 363 others, Hayward, C., Ward-Caviness, C., O’Donnell, C., Chasman, D., Strachan, D. P., Tregouet, D. A., Mook-Kanamori, D., Gill, D., Thibord, F., Asselbergs, F. W., Leebeek, F. W. G., Rosendaal, F. R., Davies, G., Homuth, G., Temprano, G., Campbell, H., Taylor, H. A., Bressler, J., Huffman, J. E., Rotter, J. I., Yao, J., Wilson, J. F., Bis, J. C., Hahn, J. M., Desch, K. C., Wiggins, K. L., Raffield, L. M., Bielak, L. F., Yanek, L. R., Kleber, M. E., Mueller, M., Kavousi, M., Mangino, M., Liu, M., Brown, M. R., Conomos, M. P., Jhun, M. A., Chen, M. H., de Maat, M. P. M., Pankratz, N., Smith, N. L., Peyser, P. A., Elliot, P., Wei, P., Wild, P. S., Morange, P. E., van der Harst, P., Yang, Q., Le, N. Q., Marioni, R., Li, R., Damrauer, S. M., Cox, S. R., Trompet, S., Felix, S. B., Völker, U., Tang, W., Koenig, W., Jukema, J. W., Guo, X., Lindstrom, S., Wang, L., Smith, E. N., Gordon, W., van Hylckama Vlieg, A., de Andrade, M., Brody, J. A., Pattee, J. W., Haessler, J., Brumpton, B. M., Suchon, P., Chen, M. H., Turman, C., Germain, M., Wiggins, K. L., MacDonald, J., Braekkan, S. K., Armasu, S. M., Pankratz, N., Jackson, R. D., Nielsen, J. B., Giulianini, F., Puurunen, M. K., Ibrahim, M., Heckbert, S. R., Bammler, T. K., Frazer, K. A., McCauley, B. M., Taylor, K., Pankow, J. S., Reiner, A. P., Gabrielsen, M. E., Deleuze, J. F., O’Donnell, C. J., Kim, J., McKnight, B., Kraft, P., Hansen, J. B., Rosendaal, F. R., Heit, J. A., Psaty, B. M., Tang, W., Kooperberg, C., Hveem, K., Ridker, P. M., Morange, P. E., Johnson, A. D., Kabrhel, C., Trégouët, D. A., Smith, N. L., Malik, R., Chauhan, G., Traylor, M., Sargurupremraj, M., Okada, Y., Mishra, A., Rutten-Jacobs, L., Giese, A. K., van der Laan, S. W., Gretarsdottir, S., Anderson, C. D., Chong, M., Adams, H. H. H., Ago, T., Almgren, P., Amouyel, P., Ay, H., Bartz, T. M., Benavente, O. R., Bevan, S., Boncoraglio, G. B., Brown, R. D., Butterworth, A. S., Carrera, C., Carty, C. L., Chen, W. M., Cole, J. W., Correa, A., Cotlarciuc, I., Cruchaga, C., Danesh, J., de Bakker, P. I. W., DeStefano, A. L., den Hoed, M., Duan, Q., Engelter, S. T., Falcone, G. J., Gottesman, R. F., Grewal, R. P., Gudnason, V., Gustafsson, S., Haessler, J., Harris, T. B., Hassan, A., Havulinna, A. S., Heckbert, S. R., Holliday, E. G., Howard, G., Hsu, F. C., Hyacinth, H. I., Arfan Ikram, M., Ingelsson, E., Irvin, M. R., Jian, X., Jiménez-Conde, J., Johnson, J. A., Jukema, J. W., Kanai, M., Keene, K. L., Kissela, B. M., Kleindorfer, D. O., Kooperberg, C., Kubo, M., Lange, L. A., Langefeld, C. D., Langenberg, C., Launer, L. J., Lee, J. M., Lemmens, R., Leys, D., Lewis, C. M., Lin, W. Y., Lindgren, A. G., Lorentzen, E., Magnusson, P. K., Maguire, J., Manichaikul, A., McArdle, P. F., Meschia, J. F., Mitchell, B. D., Mosley, T. H., Nalls, M. A., Ninomiya, T., O’Donnell, M. J., Psaty, B. M., Pulit, S. L., Rannikmäe, K., Reiner, A. P., Rexrode, K. M., Rice, K., Rich, S. S., Ridker, P. M., Rost, N. S., Rothwell, P. M., Rotter, J. I., Rundek, T., Sacco, R. L., Sakaue, S., Sale, M. M., Salomaa, V., Sapkota, B. R., Schmidt, R., Schmidt, C. O., Schminke, U., Sharma, P., Slowik, A., Sudlow, C. L. M., Tanislav, C., Tatlisumak, T., Taylor, K. D., Thijs, V. N. S., Thorleifsson, G., Thorsteinsdottir, U., Tiedt, S., Trompet, S., Tzourio, C., van Duijn, C. M., Walters, M., Wareham, N. J., Wassertheil-Smoller, S., Wilson, J. G., Wiggins, K. L., Yang, Q., Yusuf, S., Amin, N., Aparicio, H. S., Arnett, D. K., Attia, J., Beiser, A. S., Berr, C., Buring, J. E., Bustamante, M., Caso, V., Cheng, Y. C., Hoan Choi, S., Chowhan, A., Cullell, N., Dartigues, J. F., Delavaran, H., Delgado, P., Dörr, M., Engström, G., Ford, I., Gurpreet, W. S., Hamsten, A., Heitsch, L., Hozawa, A., Ibanez, L., Ilinca, A., Ingelsson, M., Iwasaki, M., Jackson, R. D., Jood, K., Jousilahti, P., Kaffashian, S., Kalra, L., Kamouchi, M., Kitazono, T., Kjartansson, O., Kloss, M., Koudstaal, P. J., Krupinski, J., Labovitz, D. L., Laurie, C. C., Levi, C. R., Li, L., Lind, L., Lindgren, C. M., Lioutas, V., Mei Liu, Y., Lopez, O. L., Makoto, H., Martinez-Majander, N., Matsuda, K., Minegishi, N., Montaner, J., Morris, A. P., Muiño, E., Müller-Nurasyid, M., Norrving, B., Ogishima, S., Parati, E. A., Reddy Peddareddygari, L., Pedersen, N. L., Pera, J., Perola, M., Pezzini, A., Pileggi, S., Rabionet, R., Riba-Llena, I., Ribasés, M., Romero, J. R., Roquer, J., Rudd, A. G., Sarin, A. P., Sarju, R., Sarnowski, C., Sasaki, M., Satizabal, C. L., Satoh, M., Sattar, N., Sawada, N., Sibolt, G., Sigurdsson, Á., Smith, A., Sobue, K., Soriano-Tárraga, C., Stanne, T., Colin Stine, O., Stott, D. J., Strauch, K., Takai, T., Tanaka, H., Tanno, K., Teumer, A., Tomppo, L., Torres-Aguila, N. P., Touze, E., Tsugane, S., Uitterlinden, A. G., Valdimarsson, E. M., van der Lee, S. J., Völzke, H., Wakai, K., Weir, D., Williams, S. R., Wolfe, C. D. A., Wong, Q., Xu, H., Yamaji, T., Sanghera, D. K., Melander, O., Jern, C., Strbian, D., Fernandez-Cadenas, I., Longstreth, W. T., Rolfs, A., Hata, J., Woo, D., Rosand, J., Pare, G., Hopewell, J. C., Saleheen, D., Stefansson, K., Worrall, B. B., Kittner, S. J., Seshadri, S., Fornage, M., Markus, H. S., Howson, J. M. M., Kamatani, Y., Debette, S. & Dichgans, M., Jun 1 2022, In: Journal of Thrombosis and Haemostasis. 20, 6, p. 1331-1349 19 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

New insights into the genetic etiology of Alzheimer’s disease and related dementias

EADB, GR@ACE, DEGESCO, EADI, GERAD, Demgene, FinnGen, ADGC & CHARGE, Apr 1 2022, In: Nature Genetics. 54, 4, p. 412-436 25 p.

Research output: Contribution to journal › Article › peer-review

Open Access

851 Scopus citations

Resilience at High Resolution: Proteomics in the Study of Brain Reserve

McDade, E. & Ibanez, L., Mar 29 2022, In: Neurology. 98, 13, p. 519-520 2 p.

Research output: Contribution to journal › Editorial

2 Scopus citations

2021

Advances in genetic and molecular understanding of alzheimer’s disease

Ibanez, L., Cruchaga, C. & Fernández, M. V., Aug 2021, In: Genes. 12, 8, 1247.

Research output: Contribution to journal › Review article › peer-review

Open Access

12 Scopus citations

Causal Effect of MMP-1 (Matrix Metalloproteinase-1), MMP-8, and MMP-12 Levels on Ischemic Stroke: A Mendelian Randomization Study

Cárcel-Márquez, J., Cullell, N., Muiño, E., Gallego-Fabrega, C., Lledós, M., Ibañez, L., Krupinski, J., Montaner, J., Cruchaga, C., Lee, J. M., Gill, D., Paré, G., Mola-Caminal, M., Roquer, J., Jimenez-Conde, J., Martí-Fàbregas, J. & Fernandez-Cadenas, I., Jul 1 2021, In: Stroke. 52, 7, p. E316-E320

Research output: Contribution to journal › Article › peer-review

Open Access

26 Scopus citations

Early Neurological Change After Ischemic Stroke Is Associated With 90-Day Outcome

Heitsch, L., Ibanez, L., Carrera, C., Binkley, M. M., Strbian, D., Tatlisumak, T., Bustamante, A., Ribó, M., Molina, C., Dávalos, A., López-Cancio, E., Muñoz-Narbona, L., Soriano-Tárraga, C., Giralt-Steinhauer, E., Obach, V., Slowik, A., Pera, J., Lapicka-Bodzioch, K., Derbisz, J. & Sobrino, T. & 30 others, Castillo, J., Campos, F., Rodríguez-Castro, E., Arias-Rivas, S., Segura, T., Serrano-Heras, G., Vives-Bauza, C., Díaz-Navarro, R., Tur, S., Jimenez, C., Martí-Fàbregas, J., Delgado-Mederos, R., Arenillas, J., Krupinski, J., Cullell, N., Torres-Aguila, N. P., Muiño, E., Cárcel-Márquez, J., Moniche, F., Cabezas, J. A., Ford, A. L., Dhar, R., Roquer, J., Khatri, P., Jiménez-Conde, J., Fernandez-Cadenas, I., Montaner, J., Rosand, J., Cruchaga, C. & Lee, J. M., Jan 1 2021, In: Stroke. 52, 1, p. 132-141 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

39 Scopus citations

Editorial for the genetics of alzheimer’s disease special issue: October 2021

Ibanez, L., Nov 2021, In: Genes. 12, 11, 1794.

Research output: Contribution to journal › Editorial

Open Access

Exome-wide rare variant analysis in familial essential tremor

University of Washington Center for Mendelian Genomics (UWCMG), Jan 2021, In: Parkinsonism and Related Disorders. 82, p. 109-116 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

Genomic atlas of the proteome from brain, CSF and plasma prioritizes proteins implicated in neurological disorders

Yang, C., Farias, F. H. G., Ibanez, L., Suhy, A., Sadler, B., Fernandez, M. V., Wang, F., Bradley, J. L., Eiffert, B., Bahena, J. A., Budde, J. P., Li, Z., Dube, U., Sung, Y. J., Mihindukulasuriya, K. A., Morris, J. C., Fagan, A. M., Perrin, R. J., Benitez, B. A. & Rhinn, H. & 2 others, Harari, O. & Cruchaga, C., Sep 2021, In: Nature neuroscience. 24, 9, p. 1302-1312 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

111 Scopus citations

Rp11-362k2.2:Rp11-767i20.1 genetic variation is associated with post-reperfusion therapy parenchymal hematoma. a gwas meta-analysis

International Stroke Genetic Consortium & Spanish Stroke Genetic Consortium, Jul 2 2021, In: Journal of Clinical Medicine. 10, 14, 3137.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

Single nucleotide variations in ZBTB46 are associated with post-thrombolytic parenchymal haematoma

The International Stroke Genetic Consortium and the Spanish Stroke Genetic Consortium, Aug 1 2021, In: Brain. 144, 8, p. 2416-2426 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

2020

CCL23: A Chemokine Associated with Progression from Mild Cognitive Impairment to Alzheimer's Disease

Faura, J., Bustamante, A., Penalba, A., Giralt, D., Simats, A., Martínez-Sáez, E., Alcolea, D., Fortea, J., Lleó, A., Teunissen, C. E., Van Der Flier, W. M., Ibañez, L., Harari, O., Cruchaga, C., Hernández-Guillamón, M., Delgado, P. & Montaner, J., 2020, In: Journal of Alzheimer's Disease. 73, 4, p. 1585-1595 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

25 Scopus citations

Correction to: Overlapping genetic architecture between Parkinson disease and melanoma (Acta Neuropathologica, (2020), 139, 2, (347-364), 10.1007/s00401-019-02110-z)

23andMe Research Team, Melanoma-Meta-analysis Consortium, GenoMEL Consortium, Essen-Heidelberg Investigators, SDH Study Group, Q-MEGA and QTWIN Investigators, AMFS Investigators & ATHENS Melanoma Study Group, May 1 2020, In: Acta Neuropathologica. 139, 5, p. 963 1 p.

Research output: Contribution to journal › Comment/debate

Open Access

Examination of the Effect of Rare Variants in TREM2, ABI3, and PLCG2 in LOAD through Multiple Phenotypes

Olive, C., Ibanez, L., Farias, F. H. G., Wang, F., Budde, J. P., Norton, J. B., Gentsch, J., Morris, J. C., Li, Z., Dube, U., Del-Aguila, J., Bergmann, K., Bradley, J., Benitez, B. A., Harari, O., Fagan, A., Ances, B., Cruchaga, C. & Fernandez, M. V., 2020, In: Journal of Alzheimer's Disease. 77, 4, p. 1469-1482 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

Functional genomic analyses uncover APOE-mediated regulation of brain and cerebrospinal fluid beta-amyloid levels in Parkinson disease

Ibanez, L., Bahena, J. A., Yang, C., Dube, U., Farias, F. H. G., Budde, J. P., Bergmann, K., Brenner-Webster, C., Morris, J. C., Perrin, R. J., Cairns, N. J., O’Donnell, J., Álvarez, I., Diez-Fairen, M., Aguilar, M., Miller, R., Davis, A. A., Pastor, P., Kotzbauer, P. & Campbell, M. C. & 5 others, Perlmutter, J. S., Rhinn, H., Harari, O., Cruchaga, C. & Benitez, B. A., Dec 2020, In: Acta Neuropathologica Communications. 8, 1, 196.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Human immunodeficiency virus continuum of care in 11 european union countries at the end of 2016 overall and by key population: Have we made progress?

European HIV Continuum of Care Working Group, Dec 1 2020, In: Clinical Infectious Diseases. 71, 11, p. 2905-2916 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

Overlapping genetic architecture between Parkinson disease and melanoma

GenoMEL Consortium, Essen-Heidelberg Investigators, SDH Study Group, Q-MEGA and QTWIN Investigators, AMFS Investigators, ATHENS Melanoma Study Group, Melanoma-Meta-analysis Consortium & 23andMe Research Team, Feb 1 2020, In: Acta Neuropathologica. 139, 2, p. 347-364 18 p.

Research output: Contribution to journal › Article › peer-review

Open Access

21 Scopus citations

The influence of CYP enzymes and ABCB1 on treatment outcomes in schizophrenia: association of CYP1A2 activity with adverse effects

Cendrós, M., Arranz, M. J., Torra, M., Penadés, R., Gonzalez-Rodriguez, A., Brunet, M., Perez-Blanco, J., Ibáñez, L., Serra, A. & Catalán, R., 2020, In: Journal of Translational Genetics and Genomics. 4, p. 210-220 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

The TMEM106B FTLD-protective variant, rs1990621, is also associated with increased neuronal proportion

Li, Z., Farias, F. H. G., Dube, U., Del-Aguila, J. L., Mihindukulasuriya, K. A., Fernandez, M. V., Ibanez, L., Budde, J. P., Wang, F., Lake, A. M., Deming, Y., Perez, J., Yang, C., Bahena, J. A., Qin, W., Bradley, J. L., Davenport, R., Bergmann, K., Morris, J. C. & Perrin, R. J. & 4 others, Benitez, B. A., Dougherty, J. D., Harari, O. & Cruchaga, C., Jan 1 2020, In: Acta Neuropathologica. 139, 1, p. 45-61 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

49 Scopus citations

2019

An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations

the Dominantly Inherited Alzheimer Network (DIAN), Nov 1 2019, In: Nature neuroscience. 22, 11, p. 1903-1912 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

236 Scopus citations

A pharmacogenetic intervention for the improvement of the safety profile of antipsychotic treatments

Arranz, M. J., Gonzalez-Rodriguez, A., Perez-Blanco, J., Penadés, R., Gutierrez, B., Ibañez, L., Arias, B., Brunet, M., Cervilla, J., Salazar, J. & Catalan, R., Dec 1 2019, In: Translational psychiatry. 9, 1, 177.

Research output: Contribution to journal › Article › peer-review

Open Access

34 Scopus citations

A single-nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain

Del-Aguila, J. L., Li, Z., Dube, U., Mihindukulasuriya, K. A., Budde, J. P., Fernandez, M. V., Ibanez, L., Bradley, J., Wang, F., Bergmann, K., Davenport, R., Morris, J. C., Holtzman, D. M., Perrin, R. J., Benitez, B. A., Dougherty, J., Cruchaga, C. & Harari, O., Aug 9 2019, In: Alzheimer's Research and Therapy. 11, 1, 71.

Research output: Contribution to journal › Article › peer-review

Open Access

113 Scopus citations

Clinical variables and genetic risk factors associated with the acute outcome of ischemic stroke: A systematic review

Acute Endophenotypes Group of the International Stroke Genetics Consortium (ISGC), Sep 2019, In: Journal of Stroke. 21, 3, p. 276-289 14 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

27 Scopus citations

Genome-wide association study of white blood cell counts in patients with ischemic stroke

Torres-Aguila, N. P., Carrera, C., Giese, A. K., Cullell, N., Muiño, E., Cárcel-Márquez, J., Gallego-Fabrega, C., González-Sánchez, J., Del Mar Freijo, M., Álvarez-Sabín, J., Molina, C., Ribó, M., Jimenez-Conde, J., Roquer, J., Sobrino, T., Campos, F., Castillo, J., Muñoz-Narbona, L., Lopez-Cancio, E. & Dàvalos, A. & 15 others, Diaz-Navarro, R., Tur, S., Vives-Bauza, C., Serrano-Heras, G., Segura, T., Krupinski, J., Delgado-Mederos, R., Martí-Fàbregas, J., Heitsch, L., Ibañez, L., Cruchaga, C., Rost, N. S., Montaner, J., Lee, J. M. & Fernandez-Cadenas, I., Dec 1 2019, In: Stroke. 50, 12, p. 3618-3621 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Overlap in the Genetic Architecture of Stroke Risk, Early Neurological Changes, and Cardiovascular Risk Factors

International Stroke Genetics Consortium and the MEGASTROKE Consortium, 2019, In: Stroke. 50, 6, p. 1339-1345 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

PATJ Low Frequency Variants Are Associated with Worse Ischemic Stroke Functional Outcome: A Genome-Wide Meta-Analysis

Mola-Caminal, M., Carrera, C., Soriano-Tárraga, C., Giralt-Steinhauer, E., Díaz-Navarro, R. M., Tur, S., Jiménez, C., Medina-Dols, A., Cullell, N., Torres-Aguila, N. P., Muiño, E., Rodríguez-Campello, A., Ois, A., Cuadrado-Godia, E., Vivanco-Hidalgo, R. M., Hernandez-Guillamon, M., Solé, M., Delgado, P., Bustamante, A. & García-Berrocoso, T. & 45 others, Mendióroz, M., Castellanos, M., Serena, J., Martí-Fàbregas, J., Segura, T., Serrano-Heras, G., Obach, V., Ribó, M., Molina, C. A., Alvarez-Sabín, J., Palomeras, E., Freijo, M., Font, M. A., Rosand, J., Rost, N. S., Gallego-Fabrega, C., Lee, J. M., Heitsch, L., Ibanez, L., Cruchaga, C., Phuah, C. L., Lemmens, R., Thijs, V., Lindgren, A., Maguire, J., Rannikmae, K., Sudlow, C. L., Jern, C., Stanne, T. M., Lorentzen, E., Muñoz-Narbona, L., Dávalos, A., López-Cancio, E., Worrall, B. B., Woo, D., Kittner, S. J., Mitchell, B. D., Montaner, J., Roquer, J., Krupinski, J., Estivill, X., Rabionet, R., Vives-Bauzá, C., Fernández-Cadenas, I. & Jimenez-Conde, J., Jan 4 2019, In: Circulation research. 124, 1, p. 114-120 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

48 Scopus citations

Publisher correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes(Nature Genetics, (2018) 50, 4, (524-537), 10.1038/s41588-018-0058-3)

AFGen Consortium, Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, International Genomics of Blood Pressure (iGEN-BP) Consortium, INVENT Consortium, STARNET, BioBank Japan Cooperative Hospital Group, COMPASS Consortium, EPIC-CVD Consortium, EPIC-InterAct Consortium, International Stroke Genetics Consortium (ISGC), METASTROKE Consortium, Neurology Working Group of the CHARGE Consortium, NINDS Stroke Genetics Network (SiGN), UK Young Lacunar DNA Study & MEGASTROKE Consortium, 2019, In: Nature Genetics. 51, 7, p. 1192-1193 2 p.

Research output: Contribution to journal › Comment/debate

Open Access

11 Scopus citations

Serum magnesium and calcium levels in relation to ischemic stroke: Mendelian randomization study

Larsson, S. C., Traylor, M., Burgess, S., Boncoraglio, G. B., Jern, C., Michaëlsson, K., Markus, H. S., Malik, R., Chauhan, G., Sargurupremraj, M., Okada, Y., Mishra, A., Rutten-Jacobs, L., Giese, A. K., Van Der Laan, S. W., Gretarsdottir, S., Anderson, C. D., Chong, M., Adams, H. H. H. & Ago, T. & 237 others, Almgren, P., Amouyel, P., Ay, H., Bartz, R. M., Benavente, O. R., Bevan, S., Brown, R. D., Butterworth, A. S., Carrera, C., Carty, C. L., Chasman, D. I., Chen, W. M., Cole, J. W., Correa, A., Cotlarciuc, I., Cruchaga, C., Danesh, J., De Bakker, P. I. W., Destefano, A. L., Hoed, M. D., Duan, Q., Engelter, S. T., Falcone, G. J., Gottesman, R. F., Grewal, R. P., Gudnason, V., Gustafsson, S., Haessler, J., Harris, T. B., Hassan, A., Havulinna, A. S., Heckbert, S. R., Holliday, E. G., Howard, G., Hsu, F. C., Hyacinth, H. I., Ikram, M. A., Ingelsson, E., Irvin, M. R., Jian, X., Jiménez-Conde, J., Johnson, J. A., Jukema, J. W., Kanai, M., Keene, K. L., Kissela, B. M., Kleindorfer, D. O., Kooperberg, C., Kubo, M., Lange, L. A., Langefeld, C. D., Langenberg, C., Launer, L. J., Lee, J. M., Lemmens, R., Leys, D., Lewis, C. M., Lin, W. Y., Lindgren, A. G., Lorentzen, E., Magnusson, P. K., Maguire, J., Manichaikul, A., McArdle, P. F., Meschia, J. F., Mitchell, B. D., Mosley, T. H., Nalls, M. A., Ninomiya, T., O'Donnell, M. J., Psaty, B. M., Pulit, S. L., Rannikmäe, K., Reiner, A. P., Rexrode, K. M., Rice, K., Rich, S. S., Ridker, P. M., Rost, N. S., Rothwell, P. M., Rotter, J. I., Rundek, T., Sacco, R. L., Sakaue, S., Sale, M. M., Salomaa, V., Sapkota, B. R., Schmidt, R., Schmidt, C. O., Schminke, U., Sharma, P., Slowik, A., Sudlow, C. L. M., Tanislav, C., Tatlisumak, T., Taylor, K. D., Thijs, V. N. S., Thorleifsson, G., Thorsteinsdottir, U., Tiedt, S., Trompet, S., Tzourio, C., Van Duijn, C. M., Walters, M., Wareham, N. J., Wassertheil-Smoller, S., Wilson, J. G., Wiggins, K. L., Yang, Q., Yusuf, S., Amin, N., Aparicio, H. S., Arnett, D. K., Attia, J., Beiser, A. S., Berr, C., Buring, J. E., Bustamante, M., Caso, V., Cheng, Y. C., Choi, S. H., Chowhan, A., Cullell, N., Dartigues, J. F., Delavaran, H., Delgado, P., Dörr, M., Engström, G., Ford, I., Gurpreet, W. S., Hamsten, A., Heitsch, L., Hozawa, A., Ibanez, L., Ilinca, A., Ingelsson, M., Iwasaki, M., Jackson, R. D., Jood, K., Jousilahti, P., Kaffashian, S., Kalra, L., Kamouchi, M., Kitazono, T., Kjartansson, O., Kloss, M., Koudstaal, P. J., Krupinski, J., Labovitz, D. L., Laurie, C. C., Levi, C. R., Li, L., Lind, L., Lindgren, C. M., Lioutas, V., Liu, Y. M., Lopez, O. L., Makoto, H., Martinez-Majander, N., Matsuda, K., Minegishi, N., Montaner, J., Morris, A. P., Muiño, E., Müller-Nurasyid, M., Norrving, B., Ogishima, S., Parati, E. A., Peddareddygari, L. R., Pedersen, N. L., Pera, J., Perola, M., Pezzini, A., Pileggi, S., Rabionet, R., Riba-Llena, I., Ribasés, M., Romero, J. R., Roquer, J., Rudd, A. G., Sarin, A. P., Sarju, R., Sarnowski, C., Sasaki, M., Satizabal, C. L., Satoh, M., Sattar, N., Sawada, N., Sibolt, G., Sigurdsson, Á., Smith, A., Sobue, K., Soriano-Tárraga, C., Stanne, T., Stine, O. C., Stott, D. J., Strauch, K., Takai, T., Tanaka, H., Tanno, K., Teumer, A., Tomppo, L., Torres-Aguila, N. P., Touze, E., Tsugane, S., Uitterlinden, A. G., Valdimarsson, E. M., Van Der Lee, S. J., Völzke, H., Wakai, K., Weir, D., Williams, S. R., Wolfe, C. D. A., Wong, Q., Xu, H., Yamaji, T., Sanghera, D. K., Melander, O., Strbian, D., Fernandez-Cadenas, I., Longstreth, W. T., Rolfs, A., Hata, J., Woo, D., Rosand, J., Pare, G., Hopewell, J. C., Saleheen, D., Stefansson, K., Worrall, B. B., Kittner, S. J., Seshadri, S., Fornage, M., Howson, J. M. M., Kamatani, Y., Debette, S. & Dichgans, M., Feb 26 2019, In: Neurology. 92, 9, p. E944-E950

Research output: Contribution to journal › Article › peer-review

Open Access

47 Scopus citations

The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer's disease risk

Deming, Y., Filipello, F., Cignarella, F., Cantoni, C., Hsu, S., Mikesell, R., Li, Z., Del-Aguila, J. L., Dube, U., Farias, F. G., Bradley, J., Budde, J., Ibanez, L., Fernandez, M. V., Blennow, K., Zetterberg, H., Heslegrave, A., Johansson, P. M., Svensson, J. & Nellgård, B. & 16 others, Lleo, A., Alcolea, D., Clarimon, J., Rami, L., Molinuevo, J. L., Suárez-Calvet, M., Morenas-Rodríguez, E., Kleinberger, G., Ewers, M., Harari, O., Haass, C., Brett, T. J., Benitez, B. A., Karch, C. M., Piccio, L. & Cruchaga, C., Aug 14 2019, In: Science translational medicine. 11, 505, eaau2291.

Research output: Contribution to journal › Article › peer-review

Open Access

155 Scopus citations

TREM2 brain transcript-specific studies in AD and TREM2 mutation carriers

Del-Aguila, J. L., Benitez, B. A., Li, Z., Dube, U., Mihindukulasuriya, K. A., Budde, J. P., Farias, F. H. G., Fernández, M. V., Ibanez, L., Jiang, S., Perrin, R. J., Cairns, N. J., Morris, J. C., Harari, O. & Cruchaga, C., May 8 2019, In: Molecular neurodegeneration. 14, 1, 18.

Research output: Contribution to journal › Article › peer-review

Open Access

62 Scopus citations

Validation of a clinical-genetics score to predict hemorrhagic transformations after rtPA

Spanish Stroke Genetic Consortium, Aug 27 2019, In: Neurology. 93, 9, p. e851-e863

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

2018

Assessment of the Genetic Architecture of Alzheimer's Disease Risk in Rate of Memory Decline

Alzheimer's Disease Neuroimaging Initiative (ADNI), 2018, In: Journal of Alzheimer's Disease. 62, 2, p. 745-756 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

42 Scopus citations

Evaluation of gene-based family-based methods to detect novel genes associated with familial late onset Alzheimer disease

NIA-LOAD family study group & NCRAD, Apr 4 2018, In: Frontiers in Neuroscience. 12, APR, 209.

Research output: Contribution to journal › Article › peer-review

Open Access

21 Scopus citations

Genetic susceptibility to invasive pneumococcal disease

Betriu, A. S., Arranz, M. J., Güerri-Fernández, R., Pérez, M., Monzón, H., Payeras, A., Andrés, M., Torviso, J., Ibañez, L., Garau, J. & Calbo, E., Apr 2018, In: Infection, Genetics and Evolution. 59, p. 126-131 6 p.

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

Neurology Working Group of the CHARGE Consortium, NINDS Stroke Genetics Network (SiGN), UK Young Lacunar DNA Study, MEGAST ROKE Consortium, AFGen Consortium, Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, International Genomics of Blood Pressure (iGEN-BP) Consortium, INVENT Consortium, STA RNET BioBank Japan Cooperative Hospital Group, COMPASS Consortium, EPIC-CVD Consortium, EPIC-InterAct Consortium, International Stroke Genetics Consortium (ISGC) & METAST ROKE Consortium, Apr 1 2018, In: Nature Genetics. 50, 4, p. 524-537 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1052 Scopus citations

Pleiotropic effects of variants in dementia genes in Parkinson disease

Ibanez, L., Dube, U., Davis, A. A., Fernandez, M. V., Budde, J., Cooper, B., Diez-Fairen, M., Ortega-Cubero, S., Pastor, P., Perlmutter, J. S., Cruchaga, C. & Benitez, B. A., Apr 10 2018, In: Frontiers in Neuroscience. 12, APR, 230.

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

Laura Ibanez

Research output

Search results