Personal profile

Research interests

We study the antigen specificity and function of CD8 T cells in the context of neurodegeneration and cancer

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  • PhD/MSTP Students

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Collaborations and top research areas from the last five years

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  • Nuclear RNA catabolism controls endogenous retroviruses, gene expression asymmetry, and dedifferentiation

    Torre, D., Fstkchyan, Y. S., Ho, J. S. Y., Cheon, Y., Patel, R. S., Degrace, E. J., Mzoughi, S., Schwarz, M., Mohammed, K., Seo, J. S., Romero-Bueno, R., Demircioglu, D., Hasson, D., Tang, W., Mahajani, S. U., Campisi, L., Zheng, S., Song, W. S., Wang, Y. C. & Shah, H. & 26 others, Francoeur, N., Soto, J., Salfati, Z., Weirauch, M. T., Warburton, P., Beaumont, K., Smith, M. L., Mulder, L., Villalta, S. A., Kessenbrock, K., Jang, C., Lee, D., De Rubeis, S., Cobos, I., Tam, O., Hammell, M. G., Seldin, M., Shi, Y., Basu, U., Sebastiano, V., Byun, M., Sebra, R., Rosenberg, B. R., Benner, C., Guccione, E. & Marazzi, I., Dec 7 2023, In: Molecular cell. 83, 23, p. 4255-4271.e9

    Research output: Contribution to journalArticlepeer-review

    Open Access
    7 Scopus citations
  • Author Correction: Clonally expanded CD8 T cells characterize amyotrophic lateral sclerosis-4 (Nature, (2022), 606, 7916, (945-952), 10.1038/s41586-022-04844-5)

    Campisi, L., Chizari, S., Ho, J. S. Y., Gromova, A., Arnold, F. J., Mosca, L., Mei, X., Fstkchyan, Y., Torre, D., Beharry, C., Garcia-Forn, M., Jiménez-Alcázar, M., Korobeynikov, V. A., Prazich, J., Fayad, Z. A., Seldin, M. M., De Rubeis, S., Bennett, C. L., Ostrow, L. W. & Lunetta, C. & 6 others, Squatrito, M., Byun, M., Shneider, N. A., Jiang, N., La Spada, A. R. & Marazzi, I., Aug 25 2022, In: Nature. 608, 7924, p. E34

    Research output: Contribution to journalComment/debate

    Open Access
  • Clonally expanded CD8 T cells characterize amyotrophic lateral sclerosis-4

    Campisi, L., Chizari, S., Ho, J. S. Y., Gromova, A., Arnold, F., Mosca, L., Mei, X., Fstkchyan, Y., Torre, D., Beharry, C., Garcia-Forn, M., Jiménez-Alcázar, M., Korobeynikov, V. A., Prazich, J., Fayad, Z. A., Seldin, M. M., De Rubeis, S., Bennett, C. L., Ostrow, L. W. & Lunetta, C. & 6 others, Squatrito, M., Byun, M., Shneider, N. A., Jiang, N., La Spada, A. R. & Marazzi, I., Jun 30 2022, In: Nature. 606, 7916, p. 945-952 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    42 Scopus citations
  • TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation

    Ho, J. S. Y., Mok, B. W. Y., Campisi, L., Jordan, T., Yildiz, S., Parameswaran, S., Wayman, J. A., Gaudreault, N. N., Meekins, D. A., Indran, S. V., Morozov, I., Trujillo, J. D., Fstkchyan, Y. S., Rathnasinghe, R., Zhu, Z., Zheng, S., Zhao, N., White, K., Ray-Jones, H. & Malysheva, V. & 33 others, Thiecke, M. J., Lau, S. Y., Liu, H., Zhang, A. J., Lee, A. C. Y., Liu, W. C., Jangra, S., Escalera, A., Aydillo, T., Melo, B. S., Guccione, E., Sebra, R., Shum, E., Bakker, J., Kaufman, D. A., Moreira, A. L., Carossino, M., Balasuriya, U. B. R., Byun, M., Albrecht, R. A., Schotsaert, M., Garcia-Sastre, A., Chanda, S. K., Miraldi, E. R., Jeyasekharan, A. D., TenOever, B. R., Spivakov, M., Weirauch, M. T., Heinz, S., Chen, H., Benner, C., Richt, J. A. & Marazzi, I., May 13 2021, In: Cell. 184, 10, p. 2618-2632.e17

    Research output: Contribution to journalArticlepeer-review

    Open Access
    75 Scopus citations
  • Hybrid Gene Origination Creates Human-Virus Chimeric Proteins during Infection

    Ho, J. S. Y., Angel, M., Ma, Y., Sloan, E., Wang, G., Martinez-Romero, C., Alenquer, M., Roudko, V., Chung, L., Zheng, S., Chang, M., Fstkchyan, Y., Clohisey, S., Dinan, A. M., Gibbs, J., Gifford, R., Shen, R., Gu, Q., Irigoyen, N. & Campisi, L. & 34 others, Huang, C., Zhao, N., Jones, J. D., van Knippenberg, I., Zhu, Z., Moshkina, N., Meyer, L., Noel, J., Peralta, Z., Rezelj, V., Kaake, R., Rosenberg, B., Wang, B., Wei, J., Paessler, S., Wise, H. M., Johnson, J., Vannini, A., Amorim, M. J., Baillie, J. K., Miraldi, E. R., Benner, C., Brierley, I., Digard, P., Łuksza, M., Firth, A. E., Krogan, N., Greenbaum, B. D., MacLeod, M. K., van Bakel, H., Garcìa-Sastre, A., Yewdell, J. W., Hutchinson, E. & Marazzi, I., Jun 25 2020, In: Cell. 181, 7, p. 1502-1517.e23

    Research output: Contribution to journalArticlepeer-review

    Open Access
    33 Scopus citations