Laura Bierut

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Laura Bierut

Alumni Endowed Professor of Psychiatry, Professor of Psychiatry

 https://orcid.org/0000-0002-9952-4810

    Willing to Mentor

    Available to Mentor:

    PhD/MSTP Students

    • 37245
      Citations
    1983 …2024

    Research activity per year

    Personal profile

    Research interests

    The primary focus of her research is the investigation of the genetic studies of psychiatric illnesses and nicotine and substance dependence, specifically the interplay between nicotine, alcohol, cocaine and other substance dependence, and psychiatric disorders. A recent project is a collaborative multisite study to perform a genome wide association of nicotine dependence using SNPs. This project is being performed in collaboration with Perlegen Sciences, Inc. and will examine 2.2 million SNPs in pooled cases and controls and follow up the most significant 40,000 SNPs with individual genotyping. In addition, 4,000 SNPs in candidate genes will be genotyped.

    Clinical interests

    Molecular biology, bipolar illness, genetics, genetic analysis, nicotine, marijuana, cocaine, alcohol dependence, smoking, substance dependence, substance abuse, major depressive disorder, alcoholism, depression, family studies

    Available to Mentor:

    • PhD/MSTP Students

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    • Cannabis, Tobacco Use, and COVID-19 Outcomes

      Griffith, N. B., Baker, T. B., Heiden, B. T., Smock, N., Pham, G., Chen, J., Yu, J., Reddy, J., Lai, A. M., Hogue, E., Bierut, L. J. & Chen, L.-S., Jun 21 2024, In: JAMA Network Open. 7, 6, p. e2417977

      Research output: Contribution to journal › Article › peer-review

      Open Access
      1 Scopus citations

    • Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder

      Nievergelt, C. M., Maihofer, A. X., Atkinson, E. G., Chen, C. Y., Choi, K. W., Coleman, J. R. I., Daskalakis, N. P., Duncan, L. E., Polimanti, R., Aaronson, C., Amstadter, A. B., Andersen, S. B., Andreassen, O. A., Arbisi, P. A., Ashley-Koch, A. E., Austin, S. B., Avdibegoviç, E., Babić, D., Bacanu, S. A. & Baker, D. G. & 215 others, Batzler, A., Beckham, J. C., Belangero, S., Benjet, C., Bergner, C., Bierer, L. M., Biernacka, J. M., Bierut, L. J., Bisson, J. I., Boks, M. P., Bolger, E. A., Brandolino, A., Breen, G., Bressan, R. A., Bryant, R. A., Bustamante, A. C., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Børglum, A. D., Børte, S., Cahn, L., Calabrese, J. R., Caldas-de-Almeida, J. M., Chatzinakos, C., Cheema, S., Clouston, S. A. P., Colodro-Conde, L., Coombes, B. J., Cruz-Fuentes, C. S., Dale, A. M., Dalvie, S., Davis, L. K., Deckert, J., Delahanty, D. L., Dennis, M. F., Desarnaud, F., DiPietro, C. P., Disner, S. G., Docherty, A. R., Domschke, K., Dyb, G., Kulenović, A. D., Edenberg, H. J., Evans, A., Fabbri, C., Fani, N., Farrer, L. A., Feder, A., Feeny, N. C., Flory, J. D., Forbes, D., Franz, C. E., Galea, S., Garrett, M. E., Gelaye, B., Gelernter, J., Geuze, E., Gillespie, C. F., Goleva, S. B., Gordon, S. D., Goçi, A., Grasser, L. R., Guindalini, C., Haas, M., Hagenaars, S., Hauser, M. A., Heath, A. C., Hemmings, S. M. J., Hesselbrock, V., Hickie, I. B., Hogan, K., Hougaard, D. M., Huang, H., Huckins, L. M., Hveem, K., Jakovljević, M., Javanbakht, A., Jenkins, G. D., Johnson, J., Jones, I., Jovanovic, T., Karstoft, K. I., Kaufman, M. L., Kennedy, J. L., Kessler, R. C., Khan, A., Kimbrel, N. A., King, A. P., Koen, N., Kotov, R., Kranzler, H. R., Krebs, K., Kremen, W. S., Kuan, P. F., Lawford, B. R., Lebois, L. A. M., Lehto, K., Levey, D. F., Lewis, C., Liberzon, I., Linnstaedt, S. D., Logue, M. W., Lori, A., Lu, Y., Luft, B. J., Lupton, M. K., Luykx, J. J., Makotkine, I., Maples-Keller, J. L., Marchese, S., Marmar, C., Martin, N. G., Martínez-Levy, G. A., McAloney, K., McFarlane, A., McLaughlin, K. A., McLean, S. A., Medland, S. E., Mehta, D., Meyers, J., Michopoulos, V., Mikita, E. A., Milani, L., Milberg, W., Miller, M. W., Morey, R. A., Morris, C. P., Mors, O., Mortensen, P. B., Mufford, M. S., Nelson, E. C., Nordentoft, M., Norman, S. B., Nugent, N. R., O’Donnell, M., Orcutt, H. K., Pan, P. M., Panizzon, M. S., Pathak, G. A., Peters, E. S., Peterson, A. L., Peverill, M., Pietrzak, R. H., Polusny, M. A., Porjesz, B., Powers, A., Qin, X. J., Ratanatharathorn, A., Risbrough, V. B., Roberts, A. L., Rothbaum, A. O., Rothbaum, B. O., Roy-Byrne, P., Ruggiero, K. J., Rung, A., Runz, H., Rutten, B. P. F., de Viteri, S. S., Salum, G. A., Sampson, L., Sanchez, S. E., Santoro, M., Seah, C., Seedat, S., Seng, J. S., Shabalin, A., Sheerin, C. M., Silove, D., Smith, A. K., Smoller, J. W., Sponheim, S. R., Stein, D. J., Stensland, S., Stevens, J. S., Sumner, J. A., Teicher, M. H., Thompson, W. K., Tiwari, A. K., Trapido, E., Uddin, M., Ursano, R. J., Valdimarsdóttir, U., Van Hooff, M., Vermetten, E., Vinkers, C. H., Voisey, J., Wang, Y., Wang, Z., Waszczuk, M., Weber, H., Wendt, F. R., Werge, T., Williams, M. A., Williamson, D. E., Winsvold, B. S., Winternitz, S., Wolf, C., Wolf, E. J., Xia, Y., Xiong, Y., Yehuda, R., Young, K. A., Young, R. M. D., Zai, C. C., Zai, G. C., Zervas, M., Zhao, H., Zoellner, L. A., Zwart, J. A., deRoon-Cassini, T., van Rooij, S. J. H., van den Heuvel, L. L., Stein, M. B., Ressler, K. J. & Koenen, K. C., May 2024, In: Nature Genetics. 56, 5, p. 792-808 17 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      15 Scopus citations

    • Investigating the Relationship Between Smoking Behavior and Global Brain Volume

      Chang, Y., Thornton, V., Chaloemtoem, A., Anokhin, A. P., Bijsterbosch, J., Bogdan, R., Hancock, D. B., Johnson, E. O. & Bierut, L. J., Jan 2024, In: Biological Psychiatry Global Open Science. 4, 1, p. 74-82 9 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      3 Scopus citations

    • Potential causal association between gut microbiome and posttraumatic stress disorder

      He, Q., Wang, W., Xu, D., Xiong, Y., Tao, C., You, C., Ma, L., Ma, J., Nievergelt, C. M., Maihofer, A. X., Klengel, T., Atkinson, E. G., Chen, C. Y., Choi, K. W., Coleman, J. R. I., Dalvie, S., Duncan, L. E., Logue, M. W., Provost, A. C. & Ratanatharathorn, A. & 165 others, Stein, M. B., Torres, K., Aiello, A. E., Almli, L. M., Amstadter, A. B., Andersen, S. B., Andreassen, O. A., Arbisi, P. A., Ashley-Koch, A. E., Austin, S. B., Avdibegovic, E., Babić, D., Bækvad-Hansen, M., Baker, D. G., Beckham, J. C., Bierut, L. J., Bisson, J. I., Boks, M. P., Bolger, E. A., Børglum, A. D., Bradley, B., Brashear, M., Breen, G., Bryant, R. A., Bustamante, A. C., Bybjerg-Grauholm, J., Calabrese, J. R., Caldas-de-Almeida, J. M., Dale, A. M., Daly, M. J., Daskalakis, N. P., Deckert, J., Delahanty, D. L., Dennis, M. F., Disner, S. G., Domschke, K., Dzubur-Kulenovic, A., Erbes, C. R., Evans, A., Farrer, L. A., Feeny, N. C., Flory, J. D., Forbes, D., Franz, C. E., Galea, S., Garrett, M. E., Gelaye, B., Gelernter, J., Geuze, E., Gillespie, C., Uka, A. G., Gordon, S. D., Guffanti, G., Hammamieh, R., Harnal, S., Hauser, M. A., Heath, A. C., Hemmings, S. M. J., Hougaard, D. M., Jakovljevic, M., Jett, M., Johnson, E. O., Jones, I., Jovanovic, T., Qin, X. J., Junglen, A. G., Karstoft, K. I., Kaufman, M. L., Kessler, R. C., Khan, A., Kimbrel, N. A., King, A. P., Koen, N., Kranzler, H. R., Kremen, W. S., Lawford, B. R., Lebois, L. A. M., Lewis, C. E., Linnstaedt, S. D., Lori, A., Lugonja, B., Luykx, J. J., Lyons, M. J., Maples-Keller, J., Marmar, C., Martin, A. R., Martin, N. G., Maurer, D., Mavissakalian, M. R., McFarlane, A., McGlinchey, R. E., McLaughlin, K. A., McLean, S. A., McLeay, S., Mehta, D., Milberg, W. P., Miller, M. W., Morey, R. A., Morris, C. P., Mors, O., Mortensen, P. B., Neale, B. M., Nelson, E. C., Nordentoft, M., Norman, S. B., O’Donnell, M., Orcutt, H. K., Panizzon, M. S., Peters, E. S., Peterson, A. L., Peverill, M., Pietrzak, R. H., Polusny, M. A., Rice, J. P., Ripke, S., Risbrough, V. B., Roberts, A. L., Rothbaum, A. O., Rothbaum, B. O., Roy-Byrne, P., Ruggiero, K., Rung, A., Rutten, B. P. F., Saccone, N. L., Sanchez, S. E., Schijven, D., Seedat, S., Seligowski, A. V., Seng, J. S., Sheerin, C. M., Silove, D., Smith, A. K., Smoller, J. W., Solovieff, N., Sponheim, S. R., Stein, D. J., Sumner, J. A., Teicher, M. H., Thompson, W. K., Trapido, E., Uddin, M., Ursano, R. J., van den Heuvel, L. L., van Hooff, M., Vermetten, E., Vinkers, C. H., Voisey, J., Wang, Y., Wang, Z., Werge, T., Williams, M. A., Williamson, D. E., Winternitz, S., Wolf, C., Wolf, E. J., Wolff, J. D., Yehuda, R., Young, K. A., Young, R. M. D., Zhao, H., Zoellner, L. A., Liberzon, I., Ressler, K. J., Haas, M. & Koenen, K. C., Dec 2024, In: Translational psychiatry. 14, 1, 67.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      2 Scopus citations

    • Smoking-informed methylation and expression QTLs in human brain and colocalization with smoking-associated genetic loci

      Carnes, M. U., Quach, B. C., Zhou, L., Han, S., Tao, R., Mandal, M., Deep-Soboslay, A., Marks, J. A., Page, G. P., Maher, B. S., Jaffe, A. E., Won, H., Bierut, L. J., Hyde, T. M., Kleinman, J. E., Johnson, E. O. & Hancock, D. B., Oct 2024, In: Neuropsychopharmacology. 49, 11, p. 1749-1757 9 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      1 Scopus citations
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