Lana Hamieh

2023

Comprehensive genetic and phenotype analysis of 95 individuals with mosaic tuberous sclerosis complex

Klonowska, K., Giannikou, K., Grevelink, J. M., Boeszoermenyi, B., Thorner, A. R., Herbert, Z. T., Afrin, A., Treichel, A. M., Hamieh, L., Kotulska, K., Jozwiak, S., Moss, J., Darling, T. N. & Kwiatkowski, D. J., Jun 1 2023, In: American journal of human genetics. 110, 6, p. 979-988 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

2022

Association of Early MRI Characteristics with Subsequent Epilepsy and Neurodevelopmental Outcomes in Children with Tuberous Sclerosis Complex

on behalf of the EPISTOP Consortium & Hamieh, L., Mar 22 2022, In: Neurology. 98, 12, p. E1216-E1225

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Evolution of electroencephalogram in infants with tuberous sclerosis complex and neurodevelopmental outcome: a prospective cohort study

the EPISTOP consortium, Apr 2022, In: Developmental Medicine and Child Neurology. 64, 4, p. 495-501 7 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

2021

Correction: Low-level mosaicism in tuberous sclerosis complex: prevalence, clinical features, and risk of disease transmission (Genetics in Medicine, (2019), 21, 11, (2639-2643), 10.1038/s41436-019-0562-6)

Giannikou, K., Lasseter, K. D., Grevelink, J. M., Tyburczy, M. E., Dies, K. A., Zhu, Z., Hamieh, L., Wollison, B. M., Thorner, A. R., Ruoss, S. J., Thiele, E. A., Sahin, M. & Kwiatkowski, D. J., Oct 2021, In: Genetics in Medicine. 23, 10, p. 2022 1 p.

Research output: Contribution to journal › Comment/debate

Open Access

1 Scopus citations

Early epileptiform EEG activity in infants with tuberous sclerosis complex predicts epilepsy and neurodevelopmental outcomes

the EPISTOP consortium, May 2021, In: Epilepsia. 62, 5, p. 1208-1219 12 p.

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Fetal Brain Magnetic Resonance Imaging Findings Predict Neurodevelopment in Children with Tuberous Sclerosis Complex

EPISTOP consortium, Jun 2021, In: Journal of Pediatrics. 233, p. 156-162.e2

Research output: Contribution to journal › Article › peer-review

Open Access

21 Scopus citations

Prevention of Epilepsy in Infants with Tuberous Sclerosis Complex in the EPISTOP Trial

the EPISTOP Investigators, Feb 1 2021, In: Annals of neurology. 89, 2, p. 304-314 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

178 Scopus citations

2020

Mutations and response to rapalogs in patients with metastatic renal cell carcinoma

Nassar, A. H., Hamieh, L., Gray, K. P., Thorner, A. R., Fay, A. P., Lasseter, K. D., Alaiwi, S. A., Nuzzo, P. V., Flippot, R., Krajewski, K. M., Signoretti, S., Choueiri, T. K. & Kwiatkowski, D. J., Feb 2020, In: Molecular Cancer Therapeutics. 19, 2, p. 690-696 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Plasma cell-free DNA variant analysis compared with methylated DNA analysis in renal cell carcinoma

Lasseter, K., Nassar, A. H., Hamieh, L., Berchuck, J. E., Nuzzo, P. V., Korthauer, K., Shinagare, A. B., Ogorek, B., McKay, R., Thorner, A. R., Lee, G. S. M., Braun, D. A., Bhatt, R. S., Freedman, M., Choueiri, T. K. & Kwiatkowski, D. J., Aug 1 2020, In: Genetics in Medicine. 22, 8, p. 1366-1373 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

47 Scopus citations

The efficacy of lenvatinib plus everolimus in patients with metastatic renal cell carcinoma exhibiting primary resistance to front-line targeted therapy or immunotherapy

Hamieh, L., Beck, R. L., Le, V. H. & Hsieh, J. J., 2020, In: Onkourologiya. 16, 3, p. 53-61 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

The Efficacy of Lenvatinib Plus Everolimus in Patients with Metastatic Renal Cell Carcinoma Exhibiting Primary Resistance to Front-Line Targeted Therapy or Immunotherapy

Hamieh, L., Beck, R. L., Le, V. H. & Hsieh, J. J., Aug 2020, In: Clinical Genitourinary Cancer. 18, 4, p. 252-257.e2

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

TSC2 pathogenic variants are predictive of severe clinical manifestations in TSC infants: results of the EPISTOP study

EPISTOP Consortium members, Sep 1 2020, In: Genetics in Medicine. 22, 9, p. 1489-1497 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

63 Scopus citations

2019

Early clinical predictors of autism spectrum disorder in infants with tuberous sclerosis complex: Results from the EPISTOP study

on behalf of the EPISTOP Consortium, Jun 2019, In: Journal of Clinical Medicine. 8, 6, 788.

Research output: Contribution to journal › Article › peer-review

Open Access

52 Scopus citations

Generalised mosaicism for TSC2 mutation in isolated lymphangioleiomyomatosis

Ogórek, B., Hamieh, L., Lasseter, K., Bagwe, S., MacHado, T., Herranz-Ors, C., Thorner, A. R., Nag, A., Gulleman, P., Giannikou, K., Young, L. R., Pujana, M. À., Darling, T. N., El-Chemaly, S., Moss, J., Henske, E. P. & Kwiatkowski, D. J., Oct 1 2019, In: European Respiratory Journal. 54, 4, 1900938.

Research output: Contribution to journal › Letter › peer-review

Open Access

6 Scopus citations

Low-level mosaicism in tuberous sclerosis complex: prevalence, clinical features, and risk of disease transmission

Giannikou, K., Lasseter, K. D., Grevelink, J. M., Tyburczy, M. E., Dies, K. A., Zhu, Z., Hamieh, L., Wollison, B. M., Thorner, A. R., Ruoss, S. J., Thiele, E. A., Sahin, M. & Kwiatkowski, D. J., Nov 1 2019, In: Genetics in Medicine. 21, 11, p. 2639-2643 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

42 Scopus citations

Phenotypic distinctions between mosaic forms of tuberous sclerosis complex

Treichel, A. M., Hamieh, L., Nathan, N. R., Tyburczy, M. E., Wang, J. A., Oyerinde, O., Raiciulescu, S., Julien-Williams, P., Jones, A. M., Gopalakrishnan, V., Moss, J., Kwiatkowski, D. J. & Darling, T. N., Nov 1 2019, In: Genetics in Medicine. 21, 11, p. 2594-2604 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

29 Scopus citations

2018

Cancer-related pain: Prevalence, severity and management in a tertiary care center in the middle east

Hamieh, N. M., Akel, R., Anouti, B., Traboulsi, C., Makki, I., Hamieh, L. & Tfayli, A., Mar 1 2018, In: Asian Pacific Journal of Cancer Prevention. 19, 3, p. 769-775 7 p.

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Characterization of Patients With Poor-Risk Metastatic Renal-Cell Carcinoma: Results From a Pooled Clinical Trials Database

Hamieh, L., McKay, R. R., Lin, X., Simantov, R. & Choueiri, T. K., Feb 2018, In: Clinical Genitourinary Cancer. 16, 1, p. 13-20.e3

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Durable clinical benefit in metastatic renal cell carcinoma patients who discontinue PD-1/PD-L1 therapy for immune-related adverse events

Martini, D. J., Hamieh, L., McKay, R. R., Harshman, L. C., Brandao, R., Norton, C. K., Steinharter, J. A., Krajewski, K. M., Gao, X., Schutz, F. A., McGregor, B., Bosse, D., Lalani, A. K. A., De Velasco, G., Dror Michaelson, M., McDermott, D. F. & Choueiri, T. K., Apr 2018, In: Cancer immunology research. 6, 4, p. 402-408 7 p.

Research output: Contribution to journal › Article › peer-review

56 Scopus citations

Impact of aspirin and non-aspirin nonsteroidal anti-inflammatory drugs on outcomes in patients with metastatic renal cell carcinoma

Hamieh, L., Moreira, R. B., Lin, X., Simantov, R., Choueiri, T. K. & McKay, R. R., 2018, In: Kidney Cancer. 2, 1, p. 37-46 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Mechanisms of acquired resistance to rapalogs in metastatic renal cell carcinoma

Hamieh, L., Choueiri, T. K., Ogórek, B., Khabibullin, D., Rosebrock, D., Livitz, D., Fay, A., Pignon, J. C., McDermott, D. F., Agarwal, N., Gao, W., Signoretti, S. & Kwiatkowski, D. J., Sep 2018, In: PLoS genetics. 14, 9, e1007679.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

Prevalence and severity of sleep disturbances among patients with early breast cancer

Fakih, R., Rahal, M., Hilal, L., Hamieh, L., Dany, M., Karam, S., Shehab, L., El Saghir, N. S., Tfayli, A., Salem, Z., Assi, H., Temraz, S., Shamseddine, A. & Mukherji, D., Jan 1 2018, In: Indian Journal of Palliative Care. 24, 1, p. 35-38 4 p.

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

2017

Effect of Metformin Use on Survival Outcomes in Patients With Metastatic Renal Cell Carcinoma

Hamieh, L., McKay, R. R., Lin, X., Moreira, R. B., Simantov, R. & Choueiri, T. K., Apr 1 2017, In: Clinical Genitourinary Cancer. 15, 2, p. 221-229 9 p.

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Expression profiles of immune-related genes are associated with neoadjuvant ipilimumab clinical benefit

Tarhini, A. A., Lin, Y., Lin, H. M., Vallabhaneni, P., Sander, C., LaFramboise, W. & Hamieh, L., Feb 1 2017, In: OncoImmunology. 6, 2, e1231291.

Research output: Contribution to journal › Article › peer-review

Open Access

30 Scopus citations

Regression of multifocoal in transit melanoma metastases after palliative resection of dominant masses and 2 years after treatment with ipilimumab

Moreira, R. B., Hamieh, L., Gjini, E., Lako, A., Krajewski, K. M., Yoon, C. H. & Ott, P. A., Jul 18 2017, In: Journal for ImmunoTherapy of Cancer. 5, 1, 61.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Younger age is an independent predictor of worse prognosis among lebanese nonmetastatic breast cancer patients: Analysis of a prospective cohort

El Chediak, A., Alameddine, R. S., Hakim, A., Hilal, L., Massih, S. A., Hamieh, L., Mukherji, D., Temraz, S., Charafeddine, M. & Shamseddine, A., Jun 10 2017, In: Breast Cancer: Targets and Therapy. 9, p. 407-414 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

2016

Mutations in TSC1, TSC2, and MTOR are associated with response to rapalogs in patients with metastatic renal cell carcinoma

Kwiatkowski, D. J., Choueiri, T. K., Fay, A. P., Rini, B. I., Thorner, A. R., De Velasco, G., Tyburczy, M. E., Hamieh, L., Albiges, L., Agarwal, N., Ho, T. H., Song, J., Pignon, J. C., Barrios, P. M., Michaelson, M. D., Van Allen, E. M., Krajewski, K. M., Porta, C., Pal, S. K. & Bellmunt, J. & 4 others, McDermott, D. F., Heng, D. Y. C., Gray, K. P. & Signoretti, S., May 15 2016, In: Clinical Cancer Research. 22, 10, p. 2445-2452 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

187 Scopus citations

Nipple Angiofibromas with Loss of TSC2 Are Associated with Tuberous Sclerosis Complex

Nathan, N., Tyburczy, M. E., Hamieh, L., Wang, J. A., Brown, G. T., Richard Lee, C. C., Kwiatkowski, D. J., Moss, J. & Darling, T. N., 2016, In: Journal of Investigative Dermatology. 136, 2, p. 535-538 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Pancreatic PEComa is a novel member of the family of tuberous sclerosis complex-associated tumors: case report and review of the literature

Hartley, C. P., Kwiatkowski, D. J., Hamieh, L., Lefferts, J. A., Smith, K. D. & Lisovsky, M., Dec 1 2016, In: Virchows Archiv. 469, 6, p. 707-710 4 p.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Pharmacogenomic Markers of Targeted Therapy Toxicity in Patients with Metastatic Renal Cell Carcinoma

de Velasco, G., Gray, K. P., Hamieh, L., Urun, Y., Carol, H. A., Fay, A. P., Signoretti, S., Kwiatkowski, D. J., McDermott, D. F., Freedman, M., Pomerantz, M. M. & Choueiri, T. K., Dec 15 2016, In: European Urology Focus. 2, 6, p. 633-639 7 p.

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

2015

Leptomeningeal metastasis as initial manifestation of signet ring colorectal adenocarcinoma: A case report with review of literature

Assi, R., Hamieh, L., Mukherji, D., Haydar, A., Temraz, S., El-Dika, I. & Shamseddine, A., 2015, In: Journal of Gastrointestinal Oncology. 6, 6, p. E89-E101

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Optimizing systemic therapy for metastatic renal cell carcinoma beyond the first-line setting

de Velasco, G., Hamieh, L., Mickey, S. & Choueiri, T. K., Dec 1 2015, In: Urologic Oncology: Seminars and Original Investigations. 33, 12, p. 538-545 8 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

12 Scopus citations

2014

From sprouting angiogenesis to erythrocytes generation by cancer stem cells: Evolving concepts in tumor microcirculation

Alameddine, R. S., Hamieh, L. & Shamseddine, A., 2014, In: BioMed Research International. 2014, 986768.

Research output: Contribution to journal › Review article › peer-review

Open Access

18 Scopus citations

2012

Role of PARP inhibitors in cancer biology and therapy

Davar, D., Beumer, J. H., Hamieh, L. & Tawbi, H., Aug 2012, In: Current Medicinal Chemistry. 19, 23, p. 3907-3921 15 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

111 Scopus citations

Lana Hamieh

Research output

Search results