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Kyle Womack

Professor of Neurology

    • 4778
      Citations
    20002022

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    • 2022

      An IL1RL1 genetic variant lowers soluble ST2 levels and the risk effects of APOE-ε4 in female patients with Alzheimer’s disease

      Alzheimer’s Disease Neuroimaging Initiative, Jul 2022, In: Nature Aging. 2, 7, p. 616-634 19 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      3 Scopus citations

    • Diagnostic Utility of Hippocampal Volumetric Data in a Memory Disorder Clinic Setting

      Ruchinskas, R., Nguyen, T., Womack, K., Khera, A., Yu, F. F. & Kelley, B. J., Mar 3 2022, In: Cognitive and Behavioral Neurology. 35, 1, p. 66-75 10 p.

      Research output: Contribution to journal › Article › peer-review

    • Dissociation of tau pathology and neuronal hypometabolism within the ATN framework of Alzheimer’s disease

      Alzheimer’s Disease Neuroimaging Initiative (ADNI), Dec 2022, In: Nature communications. 13, 1, 1495.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      3 Scopus citations

    • Glucose metabolism patterns: A potential index to characterize brain ageing and predict high conversion risk into cognitive impairment

      for the Alzheimer's Disease Neuroimaging Initiative, Aug 2022, In: GeroScience. 44, 4, p. 2319-2336 18 p.

      Research output: Contribution to journal › Article › peer-review

      2 Scopus citations

    • The trend of disruption in the functional brain network topology of Alzheimer’s disease

      for the Alzheimer's Disease Neuroimaging Initiative, Dec 2022, In: Scientific reports. 12, 1, 14998.

      Research output: Contribution to journal › Article › peer-review

      Open Access

    • Using Alzheimer's disease blood tests to accelerate clinical trial enrollment

      Schindler, S. E., Li, Y., Li, M., Despotis, A., Park, E., Vittert, L., Hamilton, B. H., Womack, K. B., Saef, B., Holtzman, D. M., Morris, J. C., Bateman, R. J. & Gupta, M. R., 2022, (Accepted/In press) In: Alzheimer's and Dementia.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      1 Scopus citations
    • 2021

      Association of Initial β-Amyloid Levels with Subsequent Flortaucipir Positron Emission Tomography Changes in Persons without Cognitive Impairment

      Alzheimer’s Disease Neuroimaging Initiative, Feb 2021, In: JAMA Neurology. 78, 2, p. 217-228 12 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      16 Scopus citations

    • Correlation between Alzheimer’s disease and type 2 diabetes using non-negative matrix factorization

      The Alzheimer’s Disease Neuroimaging Initiative, Dec 2021, In: Scientific reports. 11, 1, 15265.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      4 Scopus citations

    • Four distinct trajectories of tau deposition identified in Alzheimer’s disease

      The Alzheimer’s Disease Neuroimaging Initiative, May 2021, In: Nature medicine. 27, 5, p. 871-881 11 p.

      Research output: Contribution to journal › Article › peer-review

      136 Scopus citations

    • Higher CSF sTNFR1-related proteins associate with better prognosis in very early Alzheimer’s disease

      Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2021, In: Nature communications. 12, 1, 4001.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      9 Scopus citations

    • KL-VS heterozygosity is associated with lower amyloid-dependent tau accumulation and memory impairment in Alzheimer’s disease

      Alzheimer’s Disease Neuroimaging Initiative (ADNI), Dec 1 2021, In: Nature communications. 12, 1, 3825.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      13 Scopus citations

    • Plasma phosphorylated-tau181 as a predictive biomarker for Alzheimer’s amyloid, tau and FDG PET status

      Alzheimer’s Disease Neuroimaging Initiative, Dec 2021, In: Translational psychiatry. 11, 1, 585.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      11 Scopus citations

    • Staging tau pathology with tau PET in Alzheimer’s disease: a longitudinal study

      for the Alzheimer's Disease Neuroimaging Initiative, Dec 1 2021, In: Translational psychiatry. 11, 1, 483.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      12 Scopus citations

    • Tau-Atrophy Variability Reveals Phenotypic Heterogeneity in Alzheimer's Disease

      Alzheimer’s Disease Neuroimaging Initiative, Nov 2021, In: Annals of neurology. 90, 5, p. 751-762 12 p.

      Research output: Contribution to journal › Article › peer-review

      8 Scopus citations
    • 2020

      123I-Iofluopane Single-Photon Emission Computed Tomography as an Imaging Biomarker of Pre-Synaptic Dopaminergic System after Moderate-to-Severe Traumatic Brain Injury

      Womack, K. B., Dubiel, R., Callender, L., Dunklin, C., Dahdah, M., Harris, T. S., Devous, M. D., Juengst, S. B., Bell, K., Diaz-Arrastia, R. & Ding, K., Oct 1 2020, In: Journal of neurotrauma. 37, 19, p. 2113-2119 7 p.

      Research output: Contribution to journal › Article › peer-review

      3 Scopus citations

    • A telescope GWAS analysis strategy, based on SNPs-genes-pathways ensamble and on multivariate algorithms, to characterize late onset Alzheimer’s disease

      The Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2020, In: Scientific reports. 10, 1, 12063.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      4 Scopus citations

    • Brain Perfusion Change in Patients with Mild Cognitive Impairment after 12 Months of Aerobic Exercise Training

      Thomas, B. P., Tarumi, T., Sheng, M., Tseng, B., Womack, K. B., Munro Cullum, C., Rypma, B., Zhang, R., Lu, H. & De La Torre, J., 2020, In: Journal of Alzheimer's Disease. 75, 2, p. 617-631 15 p.

      Research output: Contribution to journal › Article › peer-review

      41 Scopus citations

    • Cerebral White Matter Integrity in Amnestic Mild Cognitive Impairment: A 1-Year Randomized Controlled Trial of Aerobic Exercise Training

      Tarumi, T., Thomas, B. P., Tseng, B. Y., Wang, C., Womack, K. B., Hynan, L., Lu, H., Cullum, C. M. & Zhang, R., 2020, In: Journal of Alzheimer's Disease. 73, 2, p. 489-501 13 p.

      Research output: Contribution to journal › Article › peer-review

      18 Scopus citations

    • Challenges and Opportunities with Causal Discovery Algorithms: Application to Alzheimer’s Pathophysiology

      The Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2020, In: Scientific reports. 10, 1, 2975.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      35 Scopus citations

    • FAM222A encodes a protein which accumulates in plaques in Alzheimer’s disease

      The Alzheimer Disease Neuroimaging Initiative, Dec 1 2020, In: Nature communications. 11, 1, 411.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      8 Scopus citations

    • Functional brain architecture is associated with the rate of tau accumulation in Alzheimer’s disease

      Alzheimer’s Disease Neuroimaging Initiative (ADNI), Dec 1 2020, In: Nature communications. 11, 1, 347.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      112 Scopus citations

    • Steady-state cerebral autoregulation in older adults with amnestic mild cognitive impairment: Linear mixed model analysis

      Zhang, L., Pasha, E. P., Liu, J., Xing, C. Y., Cardim, D., Tarumi, T., Womack, K., Hynan, L. S., Munro Cullum, C. & Zhang, R., Aug 2020, In: Journal of Applied Physiology. 129, 2, p. 377-385 9 p.

      Research output: Contribution to journal › Article › peer-review

      3 Scopus citations
    • 2019

      A blood-based signature of cerebrospinal fluid Aβ 1–42 status

      Alzheimer’s Disease Metabolomics Consortium & Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2019, In: Scientific reports. 9, 1, 4163.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      16 Scopus citations

    • Ambulatory pulse pressure, brain neuronal fiber integrity, and cerebral blood flow in older adults

      Tarumi, T., Thomas, B. P., Wang, C., Zhang, L., Liu, J., Turner, M., Riley, J., Tangella, N., Womack, K. B., Kerwin, D. R., Cullum, C. M., Lu, H., Vongpatanasin, W., Zhu, D. C. & Zhang, R., May 1 2019, In: Journal of Cerebral Blood Flow and Metabolism. 39, 5, p. 926-936 11 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      6 Scopus citations

    • A Novel Joint Brain Network Analysis Using Longitudinal Alzheimer’s Disease Data

      The Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2019, In: Scientific reports. 9, 1, 19589.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      11 Scopus citations

    • A Pilot Study of Changes in Medial Temporal Lobe Fractional Amplitude of Low Frequency Fluctuations after Sildenafil Administration in Patients with Alzheimer's Disease

      Samudra, N., Motes, M., Lu, H., Sheng, M., Diaz-Arrastia, R., Devous, M., Hart, J. & Womack, K. B., 2019, In: Journal of Alzheimer's Disease. 70, 1, p. 163-170 8 p.

      Research output: Contribution to journal › Article › peer-review

      9 Scopus citations

    • Exercise Training in Amnestic Mild Cognitive Impairment: A One-Year Randomized Controlled Trial

      Tarumi, T., Rossetti, H., Thomas, B. P., Harris, T., Tseng, B. Y., Turner, M., Wang, C., German, Z., Martin-Cook, K., Stowe, A. M., Womack, K. B., Mathews, D., Kerwin, D. R., Hynan, L., Diaz-Arrastia, R., Lu, H., Cullum, C. M., Zhang, R. & Okonkwo, O., 2019, In: Journal of Alzheimer's Disease. 71, 2, p. 421-433 13 p.

      Research output: Contribution to journal › Article › peer-review

      37 Scopus citations

    • Genome-wide association analysis of hippocampal volume identifies enrichment of neurogenesis-related pathways

      Alzheimer’s Disease Neuroimaging Initiative (ADNI), Dec 1 2019, In: Scientific reports. 9, 1, 14498.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      13 Scopus citations

    • Multimodal Hippocampal Subfield Grading For Alzheimer’s Disease Classification

      Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2019, In: Scientific reports. 9, 1, 13845.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      20 Scopus citations

    • Non-coding variability at the APOE locus contributes to the Alzheimer’s risk

      Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2019, In: Nature communications. 10, 1, 3310.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      58 Scopus citations

    • Predicting Alzheimer’s disease progression using multi-modal deep learning approach

      for Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2019, In: Scientific reports. 9, 1, 1952.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      146 Scopus citations

    • Predicting Short-term MCI-to-AD Progression Using Imaging, CSF, Genetic Factors, Cognitive Resilience, and Demographics

      For the Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2019, In: Scientific reports. 9, 1, 2235.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      31 Scopus citations

    • Regional Amyloid-β Load and White Matter Abnormalities Contribute to Hypometabolism in Alzheimer’s Dementia

      The Alzheimer’s Disease Neuroimaging Initiative, Jul 1 2019, In: Molecular Neurobiology. 56, 7, p. 4916-4924 9 p.

      Research output: Contribution to journal › Article › peer-review

      13 Scopus citations

    • Severity dependent distribution of impairments in PSP and CBS: Interactive visualizations

      The AL-108-231 Study Group, The PROPSPERA investigators, 4RNTI-1authors & Tau Restoration on PSP (TAUROS) Investigators, Mar 1 2019, In: Parkinsonism and Related Disorders. 60, p. 138-145 8 p.

      Research output: Contribution to journal › Article › peer-review

      5 Scopus citations

    • The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory

      The Alzheimer’s Disease Neuroimaging Initiative (ADNI), Dec 1 2019, In: Nature communications. 10, 1, 1766.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      43 Scopus citations

    • Type 2 diabetes mellitus, brain atrophy, and cognitive decline

      Moran, C., Beare, R., Wang, W., Callisaya, M., Srikanth, V., Weiner, M., Aisen, P., Petersen, R., Jack, C. R., Jagust, W., Trojanowki, J. Q., Toga, A. W., Beckett, L., Green, R. C., Saykin, A. J., Morris, J. C., Liu, E., Montine, T., Gamst, A., Thomas, R. G., & 233 othersDonohue, M., Walter, S., Gessert, D., Sather, T., Harvey, D., Kornak, J., Dale, A., Bernstein, M., Felmlee, J., Fox, N., Thompson, P., Schuff, N., Alexander, G., Decarli, C., Bandy, D., Koeppe, R. A., Foster, N., Reiman, E. M., Chen, K., Mathis, C., Cairns, N. J., Taylor-Reinwald, L., Trojanowki, J. Q., Shaw, L., Lee, V. M. Y., Korecka, M., Crawford, K., Neu, S., Foroud, T. M., Potkin, S., Shen, L., Kachaturian, Z., Frank, R., Snyder, P. J., Molchan, S., Kaye, J., Quinn, J., Lind, B., Dolen, S., Schneider, L. S., Pawluczyk, S., Spann, B. M., Brewer, J., Vanderswag, H., Heidebrink, J. L., Lord, J. L., Johnson, K., Doody, R. S., Villanueva-Meyer, J., Chowdhury, M., Stern, Y., Honig, L. S., Bell, K. L., Ances, B., Carroll, M., Leon, S., Mintun, M. A., Schneider, S., Marson, D., Griffith, R., Clark, D., Grossman, H., Mitsis, E., Romirowsky, A., Detoledo-Morrell, L., Shah, R. C., Duara, R., Varon, D., Roberts, P., Albert, M., Onyike, C., Kielb, S., Rusinek, H., De Leon, M. J., Glodzik, L., De Santi, S., Doraiswamy, P. M., Petrella, J. R., Coleman, R. E., Arnold, S. E., Karlawish, J. H., Wolk, D., Smith, C. D., Jicha, G., Hardy, P., Lopez, O. L., Oakley, M., Simpson, D. M., Porsteinsson, A. P., Goldstein, B. S., Martin, K., Makino, K. M., Ismail, M. S., Brand, C., Mulnard, R. A., Thai, G., McAdams-Ortiz, C., Womack, K., Mathews, D., Quiceno, M., Diaz-Arrastia, R., King, R., Weiner, M., Martin-Cook, K., Devous, M., Levey, A. I., Lah, J. J., Cellar, J. S., Burns, J. M., Anderson, H. S., Swerdlow, R. H., Apostolova, L., Lu, P. H., Bartzokis, G., Silverman, D. H. S., Graff-Radford, N. R., Parfitt, F., Johnson, H., Farlow, M. R., Hake, A. M., Matthews, B. R., Herring, S., Van Dyck, C. H., Carson, R. E., Macavoy, M. G., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Robin Hsiung, G. Y., Feldman, H., Mudge, B., Assaly, M., Kertesz, A., Rogers, J., Trost, D., Bernick, C., Munic, D., Kerwin, D., Mesulam, M. M., Lipowski, K., Wu, C. K., Johnson, N., Sadowsky, C., Martinez, W., Villena, T., Turner, R. S., Johnson, K., Reynolds, B., Sperling, R. A., Johnson, K. A., Marshall, G., Frey, M., Yesavage, J., Taylor, J. L., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M., Belden, C., Jacobson, S., Kowall, N., Killiany, R., Budson, A. E., Norbash, A., Johnson, P. L., Obisesan, T. O., Wolday, S., Bwayo, S. K., Lerner, A., Hudson, L., Ogrocki, P., Fletcher, E., Carmichael, O., Olichney, J., Kittur, S., Borrie, M., Bartha, D. R., Johnson, S., Asthana, S., Carlsson, C. M., Potkin, S. G., Preda, A., Nguyen, D., Tariot, P., Fleisher, A., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D. W., Kataki, M., Zimmerman, E. A., Celmins, D., Brown, A. D., Pearlson, G. D., Blank, K., Anderson, K., Santulli, R. B., Schwartz, E. S., Sink, K. M., Williamson, J. D., Garg, P., Watkins, F., Ott, B. R., Querfurth, H., Tremont, G., Salloway, S., Malloy, P., Correia, S., Rosen, H. J., Miller, B. L., Mintzer, J., Longmire, C. F., Spicer, K., Finger, E., Rachinsky, I., Drost, D., Pomara, N., Hernando, R., Sarrael, A., Schultz, S. K., Boles Ponto, L. L., Shim, H., Smith, K. E., Relkin, N., Chaing, G., Raudin, L., Smith, A., Fargher, K. & Raj, B. A., Feb 19 2019, In: Neurology. 92, 8, p. E823-E830

      Research output: Contribution to journal › Article › peer-review

      71 Scopus citations
    • 2018

      Brain multiplexes reveal morphological connectional biomarkers fingerprinting late brain dementia states

      Mahjoub, I., Mahjoub, M. A., Rekik, I., Weiner, M., Aisen, P., Petersen, R., Jack, C., Jagust, W., Trojanowki, J., Toga, A., Beckett, L., Green, R., Saykin, A., Morris, J., Shaw, L., Kaye, J., Quinn, J., Silbert, L., Lind, B., Carter, R., & 221 othersDolen, S., Schneider, L., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J., Lord, J., Mason, S., Albers, C., Knopman, D., Johnson, K., Doody, R., Villanueva-Meyer, J., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L., Bell, K., Ances, B., Carroll, M., Creech, M., Franklin, E., Mintun, M., Schneider, S., Oliver, A., Marson, D., Grifth, R., Clark, D., Geldmacher, D., Brockington, J., Roberson, E., Natelson Love, M., Grossman, H., Mitsis, E., Shah, R., Detoledo-Morrell, L., Duara, R., Varon, D., Greig, M., Roberts, P., Albert, M., Onyike, C., D'Agostino, D., Kielb, S., Galvin, J., Cerbone, B., Michel, C., Pogorelec, D., Rusinek, H., De Leon, M., Glodzik, L., De Santi, S., Doraiswamy, P., Petrella, J., Borges-Neto, S., Wong, T., Coleman, E., Smith, C., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Porsteinsson, A., Goldstein, B., Martin, K., Makino, K., Ismail, M., Brand, C., Mulnard, R., Thai, G., Mc-Adams-Ortiz, C., Womack, K., Mathews, D., Quiceno, M., Levey, A., Lah, J., Cellar, J., Burns, J., Swerdlow, R., Brooks, W., Apostolova, L., Tingus, K., Woo, E., Silverman, D., Lu, P., Bartzokis, G., Graf-Radford, N., Parftt, F., Kendall, T., Johnson, H., Farlow, M., Hake, A. M., Matthews, B., Brosch, J., Herring, S., Hunt, C., Dyck, C., Carson, R., MacAvoy, M., Varma, P., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Robin Hsiung, G. Y., Feldman, H., Mudge, B., Assaly, M., Finger, E., Pasternack, S., Rachisky, I., Trost, D., Kertesz, A., Bernick, C., Munic, D., Mesulam, M. M., Lipowski, K., Weintraub, S., Bonakdarpour, B., Kerwin, D., Wu, C. K., Johnson, N., Sadowsky, C., Villena, T., Turner, R. S., Johnson, K., Reynolds, B., Sperling, R., Johnson, K., Marshall, G., Yesavage, J., Taylor, J., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M., Belden, C., Jacobson, S., Sirrel, S., Kowall, N., Killiany, R., Budson, A., Norbash, A., Johnson, P. L., Obisesan, T., Wolday, S., Allard, J., Lerner, A., Ogrocki, P., Tatsuoka, C., Fatica, P., Fletcher, E., Maillard, P., Olichney, J., Decarli, C., Carmichael, O., Kittur, S., Borrie, M., Lee, T. Y., Bartha, R., Johnson, S., Asthana, S., Carlsson, C., Potkin, S., Preda, A., Nguyen, D., Tariot, P., Burke, A., Trncic, N., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D., Kataki, M., Adeli, A., Zimmerman, E., Celmins, D., Brown, A., Pearlson, G., Blank, K., Anderson, K., Flashman, L., Seltzer, M., Hynes, M., Santulli, R., Sink, K., Gordineer, L., Williamson, J., Garg, P., Watkins, F., Ott, B., Querfurth, H., Tremont, G., Salloway, S., Malloy, P., Correia, S., Rosen, H., Miller, B., Perry, D., Mintzer, J., Spicer, K., Bachman, D., Pomara, N., Hernando, R., Sarrael, A., Relkin, N., Chaing, G., Lin, M., Ravdin, L., Smith, A., Raj, B. A. & Fargher, K., Dec 1 2018, In: Scientific reports. 8, 1, 4103.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      63 Scopus citations

    • Characteristic patterns of inter- and intra-hemispheric metabolic connectivity in patients with stable and progressive mild cognitive impairment and Alzheimer’s disease

      For the Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2018, In: Scientific reports. 8, 1, 13807.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      11 Scopus citations

    • Consistency of traumatic brain injury reporting in older adults with and without cognitive impairment

      Wilmoth, K., LoBue, C., Clem, M. A., Reddy, R., Hynan, L. S., Didehbani, N., Bell, K., Womack, K. B., Hart, J., Batjer, H. & Cullum, C. M., Apr 3 2018, In: Clinical Neuropsychologist. 32, 3, p. 524-529 6 p.

      Research output: Contribution to journal › Article › peer-review

      11 Scopus citations

    • Multimodal and Multiscale Deep Neural Networks for the Early Diagnosis of Alzheimer’s Disease using structural MR and FDG-PET images

      Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2018, In: Scientific reports. 8, 1, 5697.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      185 Scopus citations

    • Traumatic brain injury and age of onset of dementia with lewy bodies

      Nguyen, T. P., Schaffert, J., Lobue, C., Womack, K. B., Hart, J. & Cullum, C. M., 2018, In: Journal of Alzheimer's Disease. 66, 2, p. 717-723 7 p.

      Research output: Contribution to journal › Article › peer-review

      14 Scopus citations

    • Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference

      The Genetic FTD Initiative (GENFI) & The Alzheimer’s Disease Neuroimaging Initiative (ADNI), Dec 1 2018, In: Nature communications. 9, 1, 4273.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      144 Scopus citations
    • 2017

      Association of plasma neurofilament light with neurodegeneration in patients with Alzheimer disease

      Alzheimer's Disease Neuroimaging Initiative, May 2017, In: JAMA Neurology. 74, 5, p. 557-566 10 p.

      Research output: Contribution to journal › Article › peer-review

      484 Scopus citations

    • Cardiorespiratory Fitness and White Matter Neuronal Fiber Integrity in Mild Cognitive Impairment

      Ding, K., Tarumi, T., Zhu, D. C., Tseng, B. Y., Thomas, B. P., Turner, M., Repshas, J., Kerwin, D. R., Womack, K. B., Lu, H., Cullum, C. M. & Zhang, R., 2017, In: Journal of Alzheimer's Disease. 61, 2, p. 729-739 11 p.

      Research output: Contribution to journal › Article › peer-review

      20 Scopus citations

    • Cascaded Multi-view Canonical Correlation (CaMCCo) for Early Diagnosis of Alzheimer's Disease via Fusion of Clinical, Imaging and Omic Features

      Singanamalli, A., Wang, H., Madabhushi, A., Weiner, M., Aisen, P., Petersen, R., Jack, C., Jagust, W., Trojanowki, J., Toga, A., Beckett, L., Green, R., Saykin, A., Morris, J., Shaw, L., Kaye, J., Quinn, J., Silbert, L., Lind, B., Carter, R., & 221 othersDolen, S., Schneider, L., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J., Lord, J., Mason, S., Albers, C., Knopman, D., Johnson, K., Doody, R., Villanueva-Meyer, J., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L., Bell, K., Ances, B., Carroll, M., Creech, M., Franklin, E., Mintun, M., Schneider, S., Oliver, A., Marson, D., Griffith, R., Clark, D., Geldmacher, D., Brockington, J., Roberson, E., Natelson Love, M., Grossman, H., Mitsis, E., Shah, R., Detoledo-Morrell, L., Duara, R., Varon, D., Greig, M., Roberts, P., Albert, M., Onyike, C., D'Agostino, D., Kielb, S., Galvin, J., Cerbone, B., Michel, C., Pogorelec, D., Rusinek, H., De Leon, M., Glodzik, L., De Santi, S., Doraiswamy, P., Petrella, J., Borges-Neto, S., Wong, T., Coleman, E., Smith, C., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Porsteinsson, A., Goldstein, B., Martin, K., Makino, K., Ismail, M., Brand, C., Mulnard, R., Thai, G., Mc-Adams-Ortiz, C., Womack, K., Mathews, D., Quiceno, M., Levey, A., Lah, J., Cellar, J., Burns, J., Swerdlow, R., Brooks, W., Apostolova, L., Tingus, K., Woo, E., Silverman, D., Lu, P., Bartzokis, G., Graff-Radford, N., Parfitt, F., Kendall, T., Johnson, H., Farlow, M., Marie Hake, A., Matthews, B., Brosch, J., Herring, S., Hunt, C., Dyck, C., Carson, R., MacAvoy, M., Varma, P., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Robin Hsiung, G. Y., Feldman, H., Mudge, B., Assaly, M., Finger, E., Pasternack, S., Rachisky, I., Trost, D., Kertesz, A., Bernick, C., Munic, D., Mesulam, M. M., Lipowski, K., Weintraub, S., Bonakdarpour, B., Kerwin, D., Wu, C. K., Johnson, N., Sadowsky, C., Villena, T., Scott Turner, R., Johnson, K., Reynolds, B., Sperling, R., Johnson, K., Marshall, G., Yesavage, J., Taylor, J., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M., Belden, C., Jacobson, S., Sirrel, S., Kowall, N., Killiany, R., Budson, A., Norbash, A., Lynn Johnson, P., Obisesan, T., Wolday, S., Allard, J., Lerner, A., Ogrocki, P., Tatsuoka, C., Fatica, P., Fletcher, E., Maillard, P., Olichney, J., Decarli, C., Carmichael, O., Kittur, S., Borrie, M., Lee, T. Y., Robbartha, Johnson, S., Asthana, S., Carlsson, C., Potkin, S., Preda, A., Nguyen, D., Tariot, P., Burke, A., Trncic, N., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D., Kataki, M., Adeli, A., Zimmerman, E., Celmins, D., Brown, A., Pearlson, G., Blank, K., Anderson, K., Flashman, L., Seltzer, M., Hynes, M., Santulli, R., Sink, K., Gordineer, L., Williamson, J., Garg, P., Watkins, F., Ott, B., Querfurth, H., Tremont, G., Salloway, S., Malloy, P., Correia, S., Rosen, H., Miller, B., Perry, D., Mintzer, J., Spicer, K., Bachman, D., Pomara, N., Hernando, R., Sarrael, A., Relkin, N., Chaing, G., Lin, M., Ravdin, L., Smith, A., Ashok Raj, B. & Fargher, K., Dec 1 2017, In: Scientific reports. 7, 1, 8137.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      8 Scopus citations

    • Longitudinal measurement and hierarchical classification framework for the prediction of Alzheimer's disease

      Huang, M., Yang, W., Feng, Q., Chen, W., Weiner, M. W., Aisen, P., Petersen, R., Jack, C. R., Jagust, W., Trojanowki, J. Q., Toga, A. W., Beckett, L., Green, R. C., Saykin, A. J., Morris, J. C., Shaw, L. M., Kaye, J., Quinn, J., Silbert, L., Lind, B., & 219 othersCarter, R., Dolen, S., Schneider, L. S., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B. M., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J. L., Lord, J. L., Mason, S. S., Albers, C. S., Knopman, D., Johnson, K., Doody, R. S., Villanueva-Meyer, J., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L. S., Bell, K. L., Ances, B., Carroll, M., Creech, M. L., Franklin, E., Mintun, M. A., Schneider, S., Oliver, A., Marson, D., Griffith, R., Clark, D., Geldmacher, D., Brockington, J., Roberson, E., Love, M. N., Grossman, H., Mitsis, E., Shah, R. C., DeToledo-Morrell, L., Duara, R., Varon, D., Greig, M. T., Roberts, P., Albert, M., Onyike, C., D'Agostino, D., Kielb, S., Galvin, J. E., Cerbone, B., Michel, C. A., Pogorelec, D. M., Rusinek, H., De Leon, M. J., Glodzik, L., De Santi, S., Murali Doraiswamy, P., Petrella, J. R., Borges-Neto, S., Wong, T. Z., Coleman, E., Smith, C. D., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Porsteinsson, A. P., Goldstein, B. S., Martin, K., Makino, K. M., Saleem Ismail, M., Brand, C., Mulnard, R. A., Thai, G., Mc-Adams-Ortiz, C., Womack, K., Mathews, D., Quiceno, M., Levey, A. I., Lah, J. J., Cellar, J. S., Burns, J. M., Swerdlow, R. H., Brooks, W. M., Apostolova, L., Tingus, K., Woo, E., Silverman, D. H. S., Lu, P. H., Bartzokis, G., Graff-Radford, N. R., Parfitt, F., Kendall, T., Johnson, H., Farlow, M. R., Hake, A. M., Brosch, J. R., Herring, S., Hunt, C., Van Dyck, C. H., Carson, R. E., MacAvoy, M. G., Varma, P., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Hsiung, G. Y. R., Feldman, H., Mudge, B., Assaly, M., Finger, E., Pasternack, S., Rachisky, I., Trost, D., Kertesz, A., Bernick, C., Munic, D., Mesulam, M. M., Lipowski, K., Weintraub, S., Bonakdarpour, B., Kerwin, D., Wu, C. K., Johnson, N., Sadowsky, C., Villena, T., Turner, R. S., Reynolds, B., Sperling, R. A., Johnson, K. A., Marshall, G., Yesavage, J., Taylor, J. L., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M. N., Belden, C. M., Jacobson, S. A., Sirrel, S. A., Kowall, N., Killiany, R., Budson, A. E., Norbash, A., Lynn Johnson, P., Obisesan, T. O., Wolday, S., Allard, J., Lerner, A., Ogrocki, P., Tatsuoka, C., Fatica, P., Maillard, P., Olichney, J., DeCarli, C., Carmichael, O., Kittur, S., Borrie, M., Lee, T. Y., Bartha, R., Johnson, S., Asthana, S., Carlsson, C. M., Potkin, S. G., Preda, A., Nguyen, D., Tariot, P., Burke, A., Trncic, N., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D. W., Kataki, M., Adeli, A., Zimmerman, E. A., Celmins, D., Brown, A. D., Pearlson, G. D., Blank, K., Anderson, K., Flashman, L. A., Seltzer, M., Hynes, M. L., Santulli, R. B., Sink, K. M., Gordineer, L., Williamson, J. D., Garg, P., Watkins, F., Ott, B. R., Querfurth, H., Tremont, G., Salloway, S., Malloy, P., Correia, S., Rosen, H. J., Miller, B. L., Perry, D., Mintzer, J., Spicer, K., Bachman, D., Pomara, N., Hernando, R., Sarrael, A., Relkin, N., Chaing, G., Lin, M., Ravdin, L., Smith, A., Raj, B. A. & Fargher, K., Jan 12 2017, In: Scientific reports. 7, 39880.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      40 Scopus citations

    • Measurement of peripheral vision reaction time identifies white matter disruption in patients with mild traumatic brain injury

      Womack, K. B., Paliotta, C., Strain, J. F., Ho, J. S., Skolnick, Y., Lytton, W. W., Turtzo, L. C., McColl, R., Diaz-Arrastia, R. & Bergold, P. J., Apr 15 2017, In: Journal of neurotrauma. 34, 8, p. 1539-1545 7 p.

      Research output: Contribution to journal › Article › peer-review

      9 Scopus citations

    • Pattern Discovery in Brain Imaging Genetics via SCCA Modeling with a Generic Non-convex Penalty

      Du, L., Liu, K., Yao, X., Yan, J., Risacher, S. L., Han, J., Guo, L., Saykin, A. J., Shen, L., Weiner, M. W., Aisen, P., Petersen, R., Jack, C. R., Jagust, W., Trojanowki, J. Q., Toga, A. W., Beckett, L., Green, R. C., Morris, J., Shaw, L. M., & 293 othersKhachaturian, Z., Sorensen, G., Carrillo, M., Kuller, L., Raichle, M., Paul, S., Davies, P., Fillit, H., Hefti, F., Holtzman, D., Mesulam, M. M., Potter, W., Snyder, P., Schwartz, A., Montine, T., Thomas, R. G., Donohue, M., Walter, S., Gessert, D., Sather, T., Jiminez, G., Balasubramanian, A. B., Mason, J., Sim, I., Harvey, D., Bernstein, M., Fox, N., Thompson, P., Schuff, N., Decarli, C., Borowski, B., Gunter, J., Senjem, M., Vemuri, P., Jones, D., Kantarci, K., Ward, C., Koeppe, R. A., Foster, N., Reiman, E. M., Chen, K., Mathis, C., Landau, S., Cairns, N. J., Franklin, E., Taylor-Reinwald, L., Lee, V., Korecka, M., Figurski, M., Crawford, K., Neu, S., Foroud, T. M., Potkin, S., Faber, K., Kim, S., Nho, K., Thal, L., Buckholtz, N., Albert, M., Frank, R., Hsiao, J., Kaye, J., Quinn, J., Silbert, L., Lind, B., Carter, R., Dolen, S., Schneider, L. S., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B. M., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J. L., Lord, J. L., Mason, S. S., Albers, C. S., Knopman, D., Johnson, K., Doody, R. S., Villanueva-Meyer, J., Pavlik, V., Shibley, V., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L. S., Bell, K. L., Ances, B., Carroll, M., Creech, M. L., Franklin, E., Mintun, M. A., Schneider, S., Oliver, A., Marson, D., Geldmacher, D., Love, M. N., Griffith, R., Clark, D., Brockington, J., Roberson, E., Grossman, H., Mitsis, E., Shah, R. C., Detoledo-Morrell, L., Duara, R., Greig-Custo, M. T., Barker, W., Onyike, C., D'Agostino, D., Kielb, S., Sadowski, M., Sheikh, M. O., Ulysse, A., Gaikwad, M., Murali Doraiswamy, P., Petrella, J. R., Borges-Neto, S., Wong, T. Z., Coleman, E., Arnold, S. E., Karlawish, J. H., Wolk, D. A., Clark, C. M., Smith, C. D., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Lopez, O. L., Oakley, M. A., Simpson, D. M., Porsteinsson, A. P., Goldstein, B. S., Martin, K., Makino, K. M., Ismail, M. S., Brand, C., Preda, A., Nguyen, D., Womack, K., Mathews, D., Quiceno, M., Levey, A. I., Lah, J. J., Cellar, J. S., Burns, J. M., Swerdlow, R. H., Brooks, W. M., Apostolova, L., Tingus, K., Woo, E., Silverman, D. H. S., Lu, P. H., Bartzokis, G., Graff-Radford, N. R., Parfitt, F., Poki-Walker, K., Farlow, M. R., Marie Hake, A., Matthews, B. R., Brosch, J. R., Herring, S., Van Dyck, C. H., Carson, R. E., MacAvoy, M. G., Varma, P., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Robin Hsiung, G. Y., Mudge, B., Sossi, V., Feldman, H., Assaly, M., Finger, E., Pasternack, S., Rachisky, I., Rogers, J., Trost, D., Kertesz, A., Bernick, C., Munic, D., Rogalski, E., Lipowski, K., Weintraub, S., Bonakdarpour, B., Kerwin, D., Wu, C. K., Johnson, N., Sadowsky, C., Villena, T., Scott Turner, R., Johnson, K., Reynolds, B., Sperling, R. A., Johnson, K. A., Marshall, G., Yesavage, J., Taylor, J. L., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M. N., Belden, C. M., Jacobson, S. A., Sirrel, S. A., Kowall, N., Killiany, R., Budson, A. E., Norbash, A., Lynn Johnson, P., Obisesan, T. O., Wolday, S., Allard, J., Lerner, A., Ogrocki, P., Tatsuoka, C., Fatica, P., Fletcher, E., Maillard, P., Olichney, J., Decarli, C., Carmichael, O., Kittur, S., Borrie, M., Lee, T. Y., Bartha, R., Johnson, S., Asthana, S., Carlsson, C. M., Tariot, P., Burke, A., Milliken, A. M., Trncic, N., Fleisher, A., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D. W., Kataki, M., Kelly, B., Zimmerman, E. A., Celmins, D., Brown, A. D., Pearlson, G. D., Blank, K., Anderson, K., Flashman, L. A., Seltzer, M., Hynes, M. L., Santulli, R. B., Sink, K. M., Gordineer, L., Williamson, J. D., Garg, P., Watkins, F., Ott, B. R., Tremont, G., Daiello, L. A., Salloway, S., Malloy, P., Correia, S., Rosen, H. J., Miller, B. L., Perry, D., Mintzer, J., Spicer, K., Bachman, D., Pomara, N., Hernando, R., Sarrael, A., Schultz, S. K., Ekstam Smith, K., Koleva, H., Nam, K. W., Shim, H., Relkin, N., Chaing, G., Lin, M., Ravdin, L., Smith, A., Ashok Raj, B. & Fargher, K., Dec 1 2017, In: Scientific reports. 7, 1, 14052.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      8 Scopus citations

    • Reduced global brain metabolism but maintained vascular function in amnestic mild cognitive impairment

      Thomas, B. P., Sheng, M., Tseng, B. Y., Tarumi, T., Martin-Cook, K., Womack, K. B., Cullum, M. C., Levine, B. D., Zhang, R. & Lu, H., 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, 4, p. 1508-1516 9 p.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      33 Scopus citations

    • Sildenafil Improves Vascular and Metabolic Function in Patients with Alzheimer's Disease

      Sheng, M., Lu, H., Liu, P., Li, Y., Ravi, H., Peng, S. L., Diaz-Arrastia, R., Devous, M. D. & Womack, K. B., 2017, In: Journal of Alzheimer's Disease. 60, 4, p. 1351-1364 14 p.

      Research output: Contribution to journal › Article › peer-review

      35 Scopus citations