Research output per year
Research output per year
Personal profile
Research interests
I manage Alafi Neuroimaging Laboratory, an imaging core facility, where I help users to design, perform and analyze experiments ranging from confocal/multiphoton imaging of fixed tissue to using advanced techniques such as FRET and photoactivation to monitor and/or change in living cell functions. I specialize in using fluorescent indicators to measure concentrations of free ions, especially calcium, in living cells. I am particularly interested in studying the mechanisms of maintaining calcium homeostasis and its dysregulation in neurons subjected to excitotoxic stimuli.
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Research output
- 40 Article
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Apolipoprotein M Attenuates Anthracycline Cardiotoxicity and Lysosomal Injury
Guo, Z., Valenzuela Ripoll, C., Picataggi, A., Rawnsley, D., Ozcan, M., Chirinos, J. A., Chendamarai, E., Girardi, A., Riehl, T., Evie, H., Diab, A., Kovacs, A., Hyrc, K., Ma, X., Asnani, A., Shewale, S. V., Scherrer-Crosbie, M., Cowart, L. A., Parks, J. S. & Zhao, L. & 14 others, , Mar 2023, In: JACC: Basic to Translational Science. 8, 3, p. 340-355 16 p.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
Novel Vaccine against Pathological Pyroglutamate-Modified Amyloid Beta for Prevention of Alzheimer’s Disease
Zagorski, K., King, O., Hovakimyan, A., Petrushina, I., Antonyan, T., Chailyan, G., Ghazaryan, M., Hyrc, K. L., Chadarevian, J. P., Davtyan, H., Blurton-Jones, M., Cribbs, D. H., Agadjanyan, M. G. & Ghochikyan, A., Jun 2023, In: International journal of molecular sciences. 24, 12, 9797.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
TRAF2, an Innate Immune Sensor, Reciprocally Regulates Mitophagy and Inflammation to Maintain Cardiac Myocyte Homeostasis
Ma, X., Rawnsley, D. R., Kovacs, A., Islam, M., Murphy, J. T., Zhao, C., Kumari, M., Foroughi, L., Liu, H., Qi, K., Diwan, A., Hyrc, K., Evans, S., Satoh, T., French, B. A., Margulies, K. B., Javaheri, A., Razani, B., Mann, D. & Mani, K. & 1 others, , Mar 2022, In: JACC: Basic to Translational Science. 7, 3, p. 223-243 21 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Beta-cell excitability and excitability-driven diabetes in adult Zebrafish islets
Emfinger, C. H., Lőrincz, R., Wang, Y., York, N. W., Singareddy, S. S., Ikle, J. M., Tryon, R. C., McClenaghan, C., Shyr, Z. A., Huang, Y., Reissaus, C. A., Meyer, D., Piston, D. W., Hyrc, K., Remedi, M. S. & Nichols, C. G., Jun 2019, In: Physiological Reports. 7, 11, e14101.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
TFEB activation in macrophages attenuates postmyocardial infarction ventricular dysfunction independently of ATG5-mediated autophagy
Javaheri, A., Bajpai, G., Picataggi, A., Mani, S., Foroughi, L., Evie, H., Kovacs, A., Weinheimer, C. J., Hyrc, K., Xiao, Q., Ballabio, A., Lee, J. M., Matkovich, S. J., Razani, B., Schilling, J. D., Lavine, K. J. & Diwan, A., Nov 1 2019, In: JCI Insight. 4, 21, e127312.Research output: Contribution to journal › Article › peer-review
Open Access38 Scopus citations