Research output per year
Research output per year
Personal profile
Research interests
Broadly, my research has three main themes: 1) identification and validation of imaging and therapeutic biomarkers in health and disease, in particular manifestation of metabolic disorders such as diabetes, obesity, cancer, and cardiovascular disease; 2) development of artificial tissue system to study tissue-specific mechanisms of disease and characterization of biomarkers; and finally, 3) computational modeling of disease mechanisms to integrate computational models with quantitative imaging techniques (such as PET) in order to personalize therapy.
Available to Mentor:
- PhD/MSTP Students
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Collaborations and top research areas from the last five years
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Deep learning generation of preclinical positron emission tomography (PET) images from low-count PET with task-based performance assessment
Dutta, K., Laforest, R., Luo, J., Jha, A. K. & Shoghi, K. I., Jun 2024, In: Medical physics. 51, 6, p. 4324-4339 16 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Detection of early-stage NASH using non-invasive hyperpolarized 13C metabolic imaging
von Morze, C., Blazey, T., Shaw, A., Spees, W. M., Shoghi, K. I. & Ohliger, M. A., Dec 2024, In: Scientific reports. 14, 1, 14854.Research output: Contribution to journal › Article › peer-review
Open Access -
Development and Use of Human Recombinant 64Cu-rHCF as a Kidney Glomerulus-Targeted Contrast Agent for Positron Emission Tomography
Baldelomar, E. J., Zhang, H., Thorek, D., Charlton, J. R., Walker, P. D., Wilson, L. D., Emoto, K. C., Clavijo Jordan, V., Reichert, D. E., Shoghi, K. & Bennett, K. M., Oct 21 2024, In: ACS Applied Bio Materials. 7, 10, p. 6392-6397 6 p.Research output: Contribution to journal › Article › peer-review
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Differential chromatin accessibility and transcriptional dynamics define breast cancer subtypes and their lineages
Iglesia, M. D., Jayasinghe, R. G., Chen, S., Terekhanova, N. V., Herndon, J. M., Storrs, E., Karpova, A., Zhou, D. C., Naser Al Deen, N., Shinkle, A. T., Lu, R. J. H., Caravan, W., Houston, A., Zhao, Y., Sato, K., Lal, P., Street, C., Martins Rodrigues, F., Southard-Smith, A. N. & Targino da Costa, A. L. N. & 40 others, , Nov 2024, In: Nature Cancer. 5, 11, p. 1713-1736 24 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Evaluation of Copanlisib in Combination with Eribulin in Triple-negative Breast Cancer Patient-derived Xenograft Models
Guo, Z., Luo, J., Jay Mashl, R., Hoog, J., Maiti, P., Fettig, N., Davies, S. R., Aft, R., Held, J. M., Govindan, R., Ding, L., Li, S., von Morze, C., Wulf, G. M., Shoghi, K. I. & Ma, C. X., Jun 2024, In: Cancer research communications. 4, 6, p. 1430-1440 11 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations