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Personal profile

Research interests

Broadly, my research has three main themes: 1) identification and validation of imaging and therapeutic biomarkers in health and disease, in particular manifestation of metabolic disorders such as diabetes, obesity, cancer, and cardiovascular disease; 2) development of artificial tissue system to study tissue-specific mechanisms of disease and characterization of biomarkers; and finally, 3) computational modeling of disease mechanisms to integrate computational models with quantitative imaging techniques (such as PET) in order to personalize therapy. 

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Research Output

Co-clinical imaging resource program (CIRP): Bridging the translational divide to advance precision medicine

Shoghi, K. I., Badea, C. T., Blocker, S. J., Chenevert, T. L., Laforest, R., Lewis, M. T., Luker, G. D., Manning, H. C., Marcus, D. S., Mowery, Y. M., Pickup, S., Richmond, A., Ross, B. D., Vilgelm, A. E., Yankeelov, T. E. & Zhou, R., Sep 2020, In : Tomography (Ann Arbor, Mich.). 6, 3, p. 273-287 15 p.

Research output: Contribution to journalArticle

Open Access
  • Hepatic lipids promote liver metastasis

    Li, Y., Su, X., Rohatgi, N., Zhang, Y., Parker, J., Shoghi, K. I., Xu, Y., Semenkovich, C., Harris, C. A., Peterson, L. L., Weibaecher, K. N., Teitelbaum, S. L. & Zou, W., Sep 3 2020, In : JCI Insight. 5, 17

    Research output: Contribution to journalArticle

    Open Access
  • In vivo Characterization of Four 18F-Labeled S1PR1 Tracers for Neuroinflammation

    Liu, H., Luo, Z., Gu, J., Jiang, H., Joshi, S., Shoghi, K., Zhou, Y., Gropler, R. J., Benzinger, T. L. S. & Tu, Z., 2020, (Accepted/In press) In : Molecular Imaging and Biology.

    Research output: Contribution to journalArticle

  • Myeloid-specific Asxl2 deletion limits diet-induced obesity by regulating energy expenditure

    Zou, W., Rohatgi, N., Brestoff, J. R., Moley, J. R., Li, Y., Williams, J. W., Alippe, Y., Pan, H., Pietka, T. A., Mbalaviele, G., Newberry, E. P., Davidson, N. O., Dey, A., Shoghi, K. I., Head, R. D., Wickline, S. A., Randolph, G. J., Abumrad, N. A. & Teitelbaum, S. L., May 1 2020, In : Journal of Clinical Investigation. 130, 5, p. 2644-2656 13 p.

    Research output: Contribution to journalArticle

    Open Access
  • 1 Scopus citations
    Open Access