Kelly Botteron

Professor of Psychiatry, Professor of Radiology

  • 5531 Citations
1991 …2020

Research output per year

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Personal profile

Research interests

My research investigates structural brain differences in children and adolescents with affective disorders, attention deficit disorder and autism. Additionally we study infants and children who are at high risk for these disorders. Currently, we are examining structural MRI differences in discordant twin populations. We have recently begun a new study to characterize very early brain development with MRI in infants at risk for developing autism. In addition, in order to better understand structural abnormalities which we and others are demonstrating in children with psychiatric disorders, we are seeking to better characterize the progress of normal structural development, by MRI, in healthy control populations. This research is done in collaboration with Robert McKinstry, M.D., Ph.D (Radiology), Joan Luby, M.D. (Psychiatry), Deanna Barch, Ph.D. (Psychology), John N. Constantino, MD (Psychiatry, Pediatrics), John R. Pruett, M.D., Ph.D. (Psychiatry), Alex Todorov, Ph.D. (Psychiatry), and David Van Essen, Ph.D. (Anatomy). Secondary to ongoing neurodevelopmental changes, image analysis methodologies need specific validation and potential modifications for use in child populations. We are involved with Dr. Michael Miller and Dr. Tilak Ratnanather’s lab (Johns Hopkins University) on the application of newer image analysis techniques, including automated 3-D, high resolution, warping atlases for child and adolescent populations.

Areas of Clinical Interest

Child and adolescent psychiatry, early onset depression, schizophrenia, obsessive compulsive disorder, Tourette's disorder, bipolar affective disorder, autism, pervasive developmental disorder, neuropsychiatry

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Research Output

  • Erratum: Joint Attention and Brain Functional Connectivity in Infants and Toddlers (Cerebral Cortex DOI: 10.1093/cercor/bhw403)

    Eggebrecht, A. T., Elison, J. T., Feczko, E., Todorov, A., Wolff, J. J., Kandala, S., Adams, C. M., Snyder, A. Z., Lewis, J. D., Estes, A. M., Zwaigenbaum, L., Botteron, K. N., McKinstry, R. C., Constantino, J. N., Evans, A., Hazlett, H. C., Dager, S., Paterson, S. J., Schultz, R. T., Styner, M. A. & 7 others, Gerig, G., Das, S., Kostopoulos, P., Schlaggar, B. L., Petersen, S. E., Piven, J. & Pruett, J. R., May 14 2020, In : Cerebral Cortex. 30, 5, p. 3433-3434 2 p.

    Research output: Contribution to journalComment/debate

    Open Access
  • "if He Has it, We Know What to Do": Parent Perspectives on Familial Risk for Autism Spectrum Disorder

    MacDuffie, K. E., Turner-Brown, L., Estes, A. M., Wilfond, B. S., Dager, S. R., Pandey, J., Zwaigenbaum, L., Botteron, K. N., Pruett, J. R., Piven, J., Peay, H. L., Piven, J., Hazlett, H. C., Chappell, C., Dager, S., Estes, A., Shaw, D., Botteron, K., McKinstry, R., Constantino, J. & 17 others, Pruett, J., Schultz, R., Pandey, J., Paterson, S., Zwaigenbaum, L., Ellison, J., Wolff, J., Evans, A. C., Collins, D. L., Pike, G. B., Fonov, V., Kostopoulos, P., Das, S., MacIntyre, L., Gerig, G., Styner, M. & Gu, H., Mar 1 2020, In : Journal of pediatric psychology. 45, 2, p. 121-130 10 p.

    Research output: Contribution to journalArticle

  • 1 Scopus citations

    Quantitative trait variation in ASD probands and toddler sibling outcomes at 24 months

    IBIS Network, Feb 5 2020, In : Journal of neurodevelopmental disorders. 12, 1, 1 p.

    Research output: Contribution to journalArticle

    Open Access
  • Sex differences associated with corpus callosum development in human infants: A longitudinal multimodal imaging study

    IBIS Network, Jul 15 2020, In : NeuroImage. 215, 116821.

    Research output: Contribution to journalArticle

    Open Access