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  • 2024

    A novel method for rapid estimation of active bone marrow dose for radiotherapy patients in epidemiological studies

    Yeom, Y. S., Braunstein, L., Morton, L. M., Bolton, K. L., Choi, J. W., Choi, H. Y., Greenstein, N. & Lee, C., Jun 2024, In: Medical physics. 51, 6, p. 4472-4481 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Predicting cytopenias, progression, and survival in patients with clonal cytopenia of undetermined significance: a prospective cohort study

    Cargo, C., Bernard, E., Beinortas, T., Bolton, K. L., Glover, P., Warren, H., Payne, D., Ali, R., Khan, A., Short, M., Van Hoppe, S., Smith, A., Taylor, J., Evans, P., Papaemmanuil, E. & Crouch, S., Jan 2024, In: The Lancet Haematology. 11, 1, p. e51-e61

    Research output: Contribution to journalArticlepeer-review

    2 Scopus citations
  • 2023

    Clinical Importance of Clonal Hematopoiesis in Metastatic Gastrointestinal Tract Cancers

    Diplas, B. H., Ptashkin, R., Chou, J. F., Sabwa, S., Foote, M. B., Rousseau, B., Argilés, G., White, J. R., Stewart, C. M., Bolton, K., Chalasani, S. B., Desai, A. M., Goldberg, Z., Gu, P., Li, J., Shcherba, M., Zervoudakis, A., Cercek, A., Yaeger, R., Segal, N. H., & 7 othersIlson, D. H., Ku, G. Y., Zehir, A., Capanu, M., Janjigian, Y. Y., Diaz, L. A. & Maron, S. B., Feb 2 2023, In: JAMA Network Open. 6, 2, e2254221.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Scopus citations
  • Clonal Hematopoiesis and Risk of Incident Lung Cancer

    Tian, R., Wiley, B., Liu, J., Zong, X., Truong, B., Zhao, S., Uddin, M. M., Niroula, A., Miller, C. A., Mukherjee, S., Heiden, B. T., Luo, J., Puri, V., Kozower, B. D., Walter, M. J., Ding, L., Link, D. C., Amos, C. I., Ebert, B. L., Govindan, R., & 3 othersNatarajan, P., Bolton, K. L. & Cao, Y., Mar 1 2023, In: Journal of Clinical Oncology. 41, 7, p. 1423-1433 11 p.

    Research output: Contribution to journalArticlepeer-review

    11 Scopus citations
  • How low can you go? Methodologic considerations in clonal hematopoiesis variant calling

    Beeler, J. S. & Bolton, K. L., Dec 2023, In: Leukemia Research. 135, 107419.

    Research output: Contribution to journalArticlepeer-review

  • Tracking the evolution of therapy-related myeloid neoplasms using chemotherapy signatures

    Diamond, B., Ziccheddu, B., Maclachlan, K., Taylor, J., Boyle, E., Ossa, J. A., Jahn, J., Affer, M., Totiger, T. M., Coffey, D., Chandhok, N., Watts, J., Cimmino, L., Lu, S. X., Bolli, N., Bolton, K., Landau, H., Park, J. H., Ganesh, K., McPherson, A., & 13 othersSekeres, M. A., Lesokhin, A., Chung, D. J., Zhang, Y., Ho, C., Roshal, M., Tyner, J., Nimer, S., Papaemmanuil, E., Usmani, S., Morgan, G., Landgren, O. & Maura, F., May 11 2023, In: Blood. 141, 19, p. 2359-2371 13 p.

    Research output: Contribution to journalArticlepeer-review

    15 Scopus citations
  • Tumor Genomic Profile Is Associated With Arterial Thromboembolism Risk in Patients With Solid Cancer

    Feldman, S., Gupta, D., Navi, B. B., Grace Ho, K. W., Willeit, P., Devlin, S., Bolton, K. L., Arcila, M. E. & Mantha, S., Apr 2023, In: JACC: CardioOncology. 5, 2, p. 246-255 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    6 Scopus citations
  • 2022

    Association of clonal hematopoiesis mutations with clinical outcomes: A systematic review and meta-analysis

    Nowakowska, M. K., Kim, T., Thompson, M. T., Bolton, K. L., Deswal, A., Lin, S. H., Scheet, P., Wehner, M. R. & Nead, K. T., Apr 2022, In: American journal of hematology. 97, 4, p. 411-420 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    13 Scopus citations
  • Bone Marrow Surveillance of Pediatric Cancer Survivors Identifies Clones that Predict Therapy-Related Leukemia

    Spitzer, B., Rutherford, K. D., Gundem, G., McGovern, E. M., Millard, N. E., Arango, J. E. O., Cheung, I. Y., Gao, T., Levine, M. F., Zhang, Y., Medina-Martínez, J. S., Feng, Y., Ptashkin, R. N., Bolton, K. L., Farnoud, N., Zhou, Y., Patel, M. A., Asimomitis, G., Cobbs, C. C., Mohibullah, N., & 10 othersHuberman, K. H., Arcilla, M. E., Kushner, B. H., Modak, S., Kung, A. L., Zehir, A., Levine, R. L., Armstron, S. A., Cheung, N. K. V. & Papaemmanuil, E., Apr 15 2022, In: Clinical Cancer Research. 28, 8, p. 1614-1627 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    4 Scopus citations
  • DNAMethylation Profiles of Ovarian Clear Cell Carcinoma

    Cunningham, J. M., Winham, S. J., Wang, C., Weiglt, B., Fu, Z., Armasu, S. M., McCauley, B. M., Brand, A. H., Chiew, Y. E., Elishaev, E., Gourley, C., Kennedy, C. J., Laslavic, A., Lester, J., Piskorz, A., Sekowska, M., Brenton, J. D., Churchman, M., DeFazio, A., Drapkin, R., & 10 othersElias, K. M., Huntsman, D. G., Karlan, B. Y., Kobel, M., Konner, J., Lawrenson, K., Papaemmanuil, E., Bolton, K. L., Modugno, F. & Goode, E. L., Jan 2022, In: Cancer Epidemiology Biomarkers and Prevention. 31, 1, p. 132-141 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    13 Scopus citations
  • Effect of Clonal Hematopoiesis on Cardiovascular Disease in People Living with HIV

    Wiley, B., Parsons, T. M., Burkart, S., Young, A. L., Erlandson, K. M., Tassiopoulos, K. K., Wu, K., Gurnett, C., Presti, R. M., Bolton, K. L. & Challen, G. A., Oct 2022, In: Experimental Hematology. 114, p. 18-21 4 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    8 Scopus citations
  • Estimation of intrafamilial DNA contamination in family trio genome sequencing using deviation from Mendelian inheritance

    Yoon, C. J., Kim, S. Y., Nam, C. H., Lee, J., Park, J. W., Mun, J., Park, S., Lee, S., Yi, B., Min, K. I., Wiley, B., Bolton, K. L., Lee, J. H., Kim, E., Yoo, H. J., Jun, J. K., Choi, J. S., Griffith, M., Griffith, O. L. & Ju, Y. S., Nov 2022, In: Genome research. 32, 11-12, p. 2134-2144 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Scopus citations
  • Molecular Subclasses of Clear Cell Ovarian Carcinoma and Their Impact on Disease Behavior and Outcomes

    Bolton, K. L., Chen, D., de la Fuente, R. C., Fu, Z., Murali, R., Köbel, M., Tazi, Y., Cunningham, J. M., Chan, I. C. C., Wiley, B. J., Moukarzel, L. A., Winham, S. J., Armasu, S. M., Lester, J., Elishaev, E., Laslavic, A., Kennedy, C. J., Piskorz, A., Sekowska, M., Brand, A. H., & 18 othersChiew, Y. E., Pharoah, P., Elias, K. M., Drapkin, R., Churchman, M., Gourley, C., DeFazio, A., Karlan, B., Brenton, J. D., Weigelt, B., Anglesio, M. S., Huntsman, D., Gayther, S., Konner, J., Modugno, F., Lawrenson, K., Goode, E. L. & Papaemmanuil, E., Nov 15 2022, In: Clinical Cancer Research. 28, 22, p. 4947-4956 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    24 Scopus citations
  • The proteome of clear cell ovarian carcinoma

    Ji, J. X., Cochrane, D. R., Negri, G. L., Colborne, S., Spencer Miko, S. E., Hoang, L. N., Farnell, D., Tessier-Cloutier, B., Huvila, J., Thompson, E., Leung, S., Chiu, D., Chow, C., Ta, M., Köbel, M., Feil, L., Anglesio, M., Goode, E. L., Bolton, K., Morin, G. B., & 1 othersHuntsman, D. G., Dec 2022, In: Journal of Pathology. 258, 4, p. 325-338 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    7 Scopus citations
  • Validated biomarker assays confirm that ARID1A loss is confounded with MMR deficiency, CD8+ TIL infiltration, and provides no independent prognostic value in endometriosis-associated ovarian carcinomas

    Heinze, K., Nazeran, T. M., Lee, S., Krämer, P., Cairns, E. S., Chiu, D. S., Leung, S. C. Y., Kang, E. Y., Meagher, N. S., Kennedy, C. J., Boros, J., Kommoss, F., Vollert, H. W., Heitz, F., du Bois, A., Harter, P., Grube, M., Kraemer, B., Staebler, A., Kommoss, F. K. F., & 62 othersHeublein, S., Sinn, H. P., Singh, N., Laslavic, A., Elishaev, E., Olawaiye, A., Moysich, K., Modugno, F., Sharma, R., Brand, A. H., Harnett, P. R., DeFazio, A., Fortner, R. T., Lubinski, J., Lener, M., Tołoczko-Grabarek, A., Cybulski, C., Gronwald, H., Gronwald, J., Coulson, P., El-Bahrawy, M. A., Jones, M. E., Schoemaker, M. J., Swerdlow, A. J., Gorringe, K. L., Campbell, I., Cook, L., Gayther, S. A., Carney, M. E., Shvetsov, Y. B., Hernandez, B. Y., Wilkens, L. R., Goodman, M. T., Mateoiu, C., Linder, A., Sundfeldt, K., Kelemen, L. E., Gentry-Maharaj, A., Widschwendter, M., Menon, U., Bolton, K. L., Alsop, J., Shah, M., Jimenez-Linan, M., Pharoah, P. D. P., Brenton, J. D., Cushing-Haugen, K. L., Harris, H. R., Doherty, J. A., Gilks, B., Ghatage, P., Huntsman, D. G., Nelson, G. S., Tinker, A. V., Lee, C. H., Goode, E. L., Nelson, B. H., Ramus, S. J., Kommoss, S., Talhouk, A., Köbel, M. & Anglesio, M. S., Apr 2022, In: Journal of Pathology. 256, 4, p. 388-401 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    13 Scopus citations
  • 2021

    Clonal hematopoiesis is associated with risk of severe Covid-19

    Bolton, K. L., Koh, Y., Foote, M. B., Im, H., Jee, J., Sun, C. H., Safonov, A., Ptashkin, R., Moon, J. H., Lee, J. Y., Jung, J., Kang, C. K., Song, K. H., Choe, P. G., Park, W. B., Kim, H. B., Oh, M. D., Song, H., Kim, S., Patel, M., & 25 othersDerkach, A., Gedvilaite, E., Tkachuk, K. A., Wiley, B. J., Chan, I. C., Braunstein, L. Z., Gao, T., Papaemmanuil, E., Esther Babady, N., Pessin, M. S., Kamboj, M., Diaz, L. A., Ladanyi, M., Rauh, M. J., Natarajan, P., Machiela, M. J., Awadalla, P., Joseph, V., Offit, K., Norton, L., Berger, M. F., Levine, R. L., Kim, E. S., Kim, N. J. & Zehir, A., Dec 1 2021, In: Nature communications. 12, 1, 5975.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    65 Scopus citations
  • Genomic profiling identifies somatic mutations predicting thromboembolic risk in patients with solid tumors

    Dunbar, A., Bolton, K. L., Devlin, S. M., Sanchez-Vega, F., Gao, J., Mones, J. V., Wills, J., Kelly, D., Farina, M., Cordner, K. B., Park, Y., Kishore, S., Juluru, K., Iyengar, N. M., Levine, R. L., Zehir, A., Park, W., Khorana, A. A., Soff, G. A. & Mantha, S., Apr 15 2021, In: Blood. 137, 15, p. 2103-2113 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    56 Scopus citations
  • Interplay between chromosomal alterations and gene mutations shapes the evolutionary trajectory of clonal hematopoiesis

    Gao, T., Ptashkin, R., Bolton, K. L., Sirenko, M., Fong, C., Spitzer, B., Menghrajani, K., Ossa, J. E. A., Zhou, Y., Bernard, E., Levine, M., Martinez, J. S. M., Zhang, Y., Franch-Expósito, S., Patel, M., Braunstein, L. Z., Kelly, D., Yabe, M., Benayed, R., Caltabellotta, N. M., & 11 othersPhilip, J., Paraiso, E., Mantha, S., Solit, D. B., Diaz, L. A., Berger, M. F., Klimek, V., Levine, R. L., Zehir, A., Devlin, S. M. & Papaemmanuil, E., Dec 2021, In: Nature communications. 12, 1, 338.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    61 Scopus citations
  • 2020

    Cancer therapy shapes the fitness landscape of clonal hematopoiesis

    Bolton, K. L., Ptashkin, R. N., Gao, T., Braunstein, L., Devlin, S. M., Kelly, D., Patel, M., Berthon, A., Syed, A., Yabe, M., Coombs, C. C., Caltabellotta, N. M., Walsh, M., Offit, K., Stadler, Z., Mandelker, D., Schulman, J., Patel, A., Philip, J., Bernard, E., & 44 othersGundem, G., Ossa, J. E. A., Levine, M., Martinez, J. S. M., Farnoud, N., Glodzik, D., Li, S., Robson, M. E., Lee, C., Pharoah, P. D. P., Stopsack, K. H., Spitzer, B., Mantha, S., Fagin, J., Boucai, L., Gibson, C. J., Ebert, B. L., Young, A. L., Druley, T., Takahashi, K., Gillis, N., Ball, M., Padron, E., Hyman, D. M., Baselga, J., Norton, L., Gardos, S., Klimek, V. M., Scher, H., Bajorin, D., Paraiso, E., Benayed, R., Arcila, M. E., Ladanyi, M., Solit, D. B., Berger, M. F., Tallman, M., Garcia-Closas, M., Chatterjee, N., Diaz, L. A., Levine, R. L., Morton, L. M., Zehir, A. & Papaemmanuil, E., Nov 1 2020, In: Nature Genetics. 52, 11, p. 1219-1226 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    330 Scopus citations
  • Chemotherapy and COVID-19 Outcomes in Patients with Cancer

    Jee, J., Foote, M. B., Lumish, M., Stonestrom, A. J., Wills, B., Narendra, V., Avutu, V., Murciano-Goroff, Y. R., Chan, J. E., Derkach, A., Philip, J., Belenkaya, R., Kerpelev, M., Maloy, M., Watson, A., Fong, C., Janjigian, Y., Diaz, L. A., Bolton, K. L. & Pessin, M. S., Oct 20 2020, In: Journal of Clinical Oncology. 38, 30, p. 3538-3546 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    191 Scopus citations
  • Clonal Hematopoiesis Before, During, and After Human Spaceflight

    Trinchant, N. M., MacKay, M. J., Chin, C., Afshinnekoo, E., Foox, J., Meydan, C., Butler, D., Mozsary, C., Vernice, N. A., Darby, C., Schatz, M. C., Bailey, S. M., Melnick, A. M., Guzman, M., Bolton, K., Braunstein, L. Z., Garrett-Bakelman, F., Levine, R. L., Hassane, D. & Mason, C. E., Dec 8 2020, In: Cell Reports. 33, 10, 108458.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    26 Scopus citations
  • Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes

    Bernard, E., Nannya, Y., Hasserjian, R. P., Devlin, S. M., Tuechler, H., Medina-Martinez, J. S., Yoshizato, T., Shiozawa, Y., Saiki, R., Malcovati, L., Levine, M. F., Arango, J. E., Zhou, Y., Solé, F., Cargo, C. A., Haase, D., Creignou, M., Germing, U., Zhang, Y., Gundem, G., & 59 othersSarian, A., van de Loosdrecht, A. A., Jädersten, M., Tobiasson, M., Kosmider, O., Follo, M. Y., Thol, F., Pinheiro, R. F., Santini, V., Kotsianidis, I., Boultwood, J., Santos, F. P. S., Schanz, J., Kasahara, S., Ishikawa, T., Tsurumi, H., Takaori-Kondo, A., Kiguchi, T., Polprasert, C., Bennett, J. M., Klimek, V. M., Savona, M. R., Belickova, M., Ganster, C., Palomo, L., Sanz, G., Ades, L., Della Porta, M. G., Smith, A. G., Werner, Y., Patel, M., Viale, A., Vanness, K., Neuberg, D. S., Stevenson, K. E., Menghrajani, K., Bolton, K. L., Fenaux, P., Pellagatti, A., Platzbecker, U., Heuser, M., Valent, P., Chiba, S., Miyazaki, Y., Finelli, C., Voso, M. T., Shih, L. Y., Fontenay, M., Jansen, J. H., Cervera, J., Atsuta, Y., Gattermann, N., Ebert, B. L., Bejar, R., Greenberg, P. L., Cazzola, M., Hellström-Lindberg, E., Ogawa, S. & Papaemmanuil, E., Oct 1 2020, In: Nature medicine. 26, 10, p. 1549-1556 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    348 Scopus citations
  • Single-cell mutation analysis of clonal evolution in myeloid malignancies

    Miles, L. A., Bowman, R. L., Merlinsky, T. R., Csete, I. S., Ooi, A. T., Durruthy-Durruthy, R., Bowman, M., Famulare, C., Patel, M. A., Mendez, P., Ainali, C., Demaree, B., Delley, C. L., Abate, A. R., Manivannan, M., Sahu, S., Goldberg, A. D., Bolton, K. L., Zehir, A., Rampal, R., & 4 othersCarroll, M. P., Meyer, S. E., Viny, A. D. & Levine, R. L., Nov 19 2020, In: Nature. 587, 7834, p. 477-482 6 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    254 Scopus citations
  • 2018

    Identification of clonal hematopoiesis mutations in solid tumor patients undergoing unpaired next-generation sequencing assays

    Coombs, C. C., Gillis, N. K., Tan, X., Berg, J. S., Ball, M., Balasis, M. E., Montgomery, N. D., Bolton, K. L., Parker, J. S., Mesa, T. E., Yoder, S. J., Hayward, M. C., Patel, N. M., Richards, K. L., Walko, C. M., Knepper, T. C., Soper, J. T., Weiss, J., Grilley-Olson, J. E., Kim, W. Y., & 6 othersShelton Earp, H., Levine, R. L., Papaemmanuil, E., Zehir, A., Neil Hayes, D. & Padron, E., Dec 1 2018, In: Clinical Cancer Research. 24, 23, p. 5918-5924 7 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    71 Scopus citations
  • Prevalence of clonal hematopoiesis mutations in tumor-only clinical genomic profiling of solid tumors

    Ptashkin, R. N., Mandelker, D. L., Coombs, C. C., Bolton, K., Yelskaya, Z., Hyman, D. M., Solit, D. B., Baselga, J., Arcila, M. E., Ladanyi, M., Zhang, L., Levine, R. L., Berger, M. F. & Zehir, A., Nov 2018, In: JAMA oncology. 4, 11, p. 1589-1593 5 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    127 Scopus citations
  • 2015

    Germline mutation in BRCA1 or BRCA2 and ten-year survival for women diagnosed with epithelial ovarian cancer

    EMBRACE, KConFab investigators & Australian Ovarian Cancer Study Group, Feb 1 2015, In: Clinical Cancer Research. 21, 3, p. 652-657 6 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    124 Scopus citations
  • 2014

    Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33

    Wang, Z., Zhu, B., Zhang, M., Parikh, H., Jia, J., Chung, C. C., Sampson, J. N., Hoskins, J. W., Hutchinson, A., Burdette, L., Ibrahim, A., Hautman, C., Raj, P. S., Abnet, C. C., Adjei, A. A., Ahlbom, A., Albanes, D., Allen, N. E., Ambrosone, C. B., Aldrich, M., & 331 othersAmiano, P., Amos, C., Andersson, U., Gerald Andriole, G. A., Andrulis, I. L., Arici, C., Arslan, A. A., Austin, M. A., Baris, D., Barkauskas, D. A., Bassig, B. A., Freeman, L. E. B., Berg, C. D., Berndt, S. I., Bertazzi, P. A., Biritwum, R. B., Black, A., Blot, W., Boeing, H., Boffetta, P., Bolton, K., Boutron-Ruault, M. C., Bracci, P. M., Brennan, P., Brinton, L. A., Brotzman, M., Bueno-de-Mesquita, H. B., Buring, J. E., Butler, M. A., Cai, Q., Cancel-Tassin, G., Canzian, F., Cao, G., Caporaso, N. E., Carrato, A., Carreon, T., Carta, A., Chang, G. C., Chang, I. S., Chang-Claude, J., Che, X., Chen, C. J., Chen, C. Y., Chen, C. H., Chen, C., Chen, K. Y., Chen, Y. M., Chokkalingam, A. P., Chu, L. W., Clavel-Chapelon, F., Colditz, G. A., Colt, J. S., Conti, D., Cook, M. B., Cortessis, V. K., Crawford, E. D., Cussenot, O., Davis, F. G., De Vivo, I., Deng, X., Ding, T., Dinney, C. P., Di Stefano, A. L., Diver, W. R., Duell, E. J., Elena, J. W., Fan, J. H., Feigelson, H. S., Feychting, M., Figueroa, J. D., Flanagan, A. M., Fraumeni, J. F., Freedman, N. D., Fridley, B. L., Fuchs, C. S., Gago-Dominguez, M., Gallinger, S., Gao, Y. T., Gapstur, S. M., Garcia-Closas, M., Garcia-Closas, R., Gastier-Foster, J. M., Gaziano, J. M., Gerhard, D. S., Giffen, C. A., Giles, G. G., Gillanders, E. M., Giovannucci, E. L., Goggins, M., Gokgoz, N., Goldstein, A. M., Gonzalez, C., Gorlick, R., Greene, M. H., Gross, M., Grossman, H. B., Grubb, R., Gu, J., Guan, P., Haiman, C. A., Hallmans, G., Hankinson, S. E., Harris, C. C., Hartge, P., Hattinger, C., Hayes, R. B., He, Q., Helman, L., Henderson, B. E., Henriksson, R., Hoffman-Bolton, J., Hohensee, C., Holly, E. A., Hong, Y. C., Hoover, R. N., Dean Hosgood, H., Hsiao, C. F., Hsing, A. W., Hsiung, C. A., Hu, N., Hu, W., Hu, Z., Huang, M. S., Hunter, D. J., Inskip, P. D., Ito, H., Jacobs, E. J., Jacobs, K. B., Jenab, M., Ji, B. T., Johansen, C., Johansson, M., Johnson, A., Kaaks, R., Kamat, A. M., Kamineni, A., Karagas, M., Khanna, C., Khaw, K. T., Kim, C., Kim, I. S., Kim, J. H., Kim, Y. H., Kim, Y. C., Kim, Y. T., Kang, C. H., Jung, Y. J., Kitahara, C. M., Klein, A. P., Klein, R., Kogevinas, M., Koh, W. P., Kohno, T., Kolonel, L. N., Kooperberg, C., Kratz, C. P., Krogh, V., Kunitoh, H., Kurtz, R. C., Kurucu, N., Lan, Q., Lathrop, M., Lau, C. C., Lecanda, F., Lee, K. M., Lee, M. P., Marchand, L. L., Lerner, S. P., Li, D., Liao, L. M., Lim, W. Y., Lin, D., Lin, J., Lindstrom, S., Linet, M. S., Lissowska, J., Liu, J., Ljungberg, B., Lloreta, J., Lu, D., Ma, J., Malats, N., Mannisto, S., Marina, N., Mastrangelo, G., Matsuo, K., McGlynn, K. A., McKean-Cowdin, R., McNeil, L. H., McWilliams, R. R., Melin, B. S., Meltzer, P. S., Mensah, J. E., Miao, X., Michaud, D. S., Mondul, A. M., Moore, L. E., Muir, K., Niwa, S., Olson, S. H., Orr, N., Panico, S., Park, J. Y., Patel, A. V., Patino-Garcia, A., Pavanello, S., Peeters, P. H. M., Peplonska, B., Peters, U., Petersen, G. M., Picci, P., Pike, M. C., Porru, S., Prescott, J., Pu, X., Purdue, M. P., Qiao, Y. L., Rajaraman, P., Riboli, E., Risch, H. A., Rodabough, R. J., Rothman, N., Ruder, A. M., Ryu, J. S., Sanson, M., Schned, A., Schumacher, F. R., Schwartz, A. G., Schwartz, K. L., Schwenn, M., Scotlandi, K., Seow, A., Serra, C., Serra, M., Sesso, H. D., Severi, G., Shen, H., Shen, M., Shete, S., Shiraishi, K., Shu, X. O., Siddiq, A., Sierrasesumaga, L., Sierri, S., Sihoe, A. D. L., Silverman, D. T., Simon, M., Southey, M. C., Spector, L., Spitz, M., Stampfer, M., Stattin, P., Stern, M. C., Stevens, V. L., Stolzenberg-Solomon, R. Z., Stram, D. O., Strom, S. S., Su, W. C., Sund, M., Sung, S. W., Swerdlow, A., Tan, W., Tanaka, H., Tang, W., Tang, Z. Z., Tardon, A., Tay, E., Taylor, P. R., Tettey, Y., Thomas, D. M., Tirabosco, R., Tjonneland, A., Tobias, G. S., Toro, J. R., Travis, R. C., Trichopoulos, D., Troisi, R., Truelove, A., Tsai, Y. H., Tucker, M. A., Tumino, R., Van Den Berg, D., Van Den Eeden, S. K., Vermeulen, R., Vineis, P., Visvanathan, K., Vogel, U., Wang, C., Wang, C., Wang, J., Wang, S. S., Weiderpass, E., Weinstein, S. J., Wentzensen, N., Wheeler, W., White, E., Wiencke, J. K., Wolk, A., Wolpin, B. M., Wong, M. P., Wrensch, M., Wu, C., Wu, T., Wu, X., Wu, Y. L., Wunder, J. S., Xiang, Y. B., Xu, J., Yang, H. P., Yang, P. C., Yatabe, Y., Ye, Y., Yeboah, E. D., Yin, Z., Ying, C., Yu, C. J., Yu, K., Yuan, J. M., Zanetti, K. A., Zeleniuch-Jacquotte, A., Zheng, W., Zhou, B., Mirabello, L., Savage, S. A., Kraft, P., Chanock, S. J., Yeager, M., Landi, M. T., Shi, J., Chatterjee, N. & Amundadottir, L. T., Nov 15 2014, In: Human molecular genetics. 23, 24, p. 6616-6633 18 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    83 Scopus citations
  • 2012

    Association between BRCA1 and BRCA2 Mutations and Survival in Women with Invasive Epithelial Ovarian Cancer

    Bolton, K. L., Chenevix-Trench, G., Goh, C., Sadetzki, S., Ramus, S. J., Karlan, B. Y., Lambrechts, D., Despierre, E., Barrowdale, D., McGuffog, L., Healey, S., Easton, D. F., Sinilnikova, O., Benítez, J., García, M. J., Neuhausen, S., Gail, M. H., Hartge, P., Peock, S., Frost, D., & 55 othersEvans, D. G., Eeles, R., Godwin, A. K., Daly, M. B., Kwong, A., Ma, E. S. K., Lázaro, C., Blanco, I., Montagna, M., D'Andrea, E., Nicoletto, M. O., Johnatty, S. E., Kjær, S. K., Jensen, A., Høgdall, E., Goode, E. L., Fridley, B. L., Loud, J. T., Greene, M. H., Mai, P. L., Chetrit, A., Lubin, F., Hirsh-Yechezkel, G., Glendon, G., Andrulis, I. L., Toland, A. E., Senter, L., Gore, M. E., Gourley, C., Michie, C. O., Song, H., Tyrer, J., Whittemore, A. S., McGuire, V., Sieh, W., Kristoffersson, U., Olsson, H., Borg, Å., Levine, D. A., Steele, L., Beattie, M. S., Chan, S., Nussbaum, R. L., Moysich, K. B., Gross, J., Cass, I., Walsh, C., Li, A. J., Leuchter, R., Gordon, O., Garcia-Closas, M., Gayther, S. A., Chanock, S. J., Antoniou, A. C. & Pharoah, P. D. P., Jan 25 2012, In: JAMA. 307, 4, p. 382-390 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    529 Scopus citations
  • Gene set analysis of survival following ovarian cancer implicates macrolide binding and intracellular signaling genes

    Fridley, B. L., Jenkins, G. D., Tsai, Y. Y., Song, H., Bolton, K. L., Fenstermacher, D., Tyrer, J., Ramus, S. J., Cunningham, J. M., Vierkant, R. A., Chen, Z., Chen, Y. A., Iversen, E., Menon, U., Gentry-Maharaj, A., Schildkraut, J., Sutphen, R., Gayther, S. A., Hartmann, L. C., Pharoah, P. D. P., & 2 othersSellers, T. A. & Goode, E. L., Mar 2012, In: Cancer Epidemiology Biomarkers and Prevention. 21, 3, p. 529-536 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    7 Scopus citations
  • 2011

    A Kallikrein 15 (KLK15) single nucleotide polymorphism located close to a novel exon shows evidence of association with poor ovarian cancer survival

    Batra, J., Nagle, C. M., O'Mara, T., Higgins, M., Dong, Y., Tan, O. L., Lose, F., Skeie, L. M., Srinivasan, S., Bolton, K. L., Song, H., Ramus, S. J., Gayther, S. A., Pharoah, P. D. P., Kedda, M. A., Spurdle, A. B. & Clements, J. A., Apr 1 2011, In: BMC Cancer. 11, 119.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    23 Scopus citations
  • The role of KRAS rs61764370 in invasive epithelial ovarian cancer: Implications for clinical testing

    Pharoah, P. D. P., Palmieri, R. T., Ramus, S. J., Gayther, S. A., Andrulis, I. L., Anton-Culver, H., Antonenkova, N., Antoniou, A. C., Goldgar, D., Beattie, M. S., Beckmann, M. W., Birrer, M. J., Bogdanova, N., Bolton, K. L., Brewster, W., Brooks-Wilson, A., Brown, R., Butzow, R., Caldes, T., Caligo, M. A., & 93 othersCampbell, I., Chang-Claude, J., Chen, Y. A., Cook, L. S., Couch, F. J., Cramer, D. W., Cunningham, J. M., Despierre, E., Doherty, J. A., Dörk, T., Dürst, M., Eccles, D. M., Ekici, A. B., Easton, D., Fasching, P. A., De Fazio, A., Fenstermacher, D. A., Flanagan, J. M., Fridley, B. L., Friedman, E., Gao, B., Sinilnikova, O., Gentry-Maharaj, A., Godwin, A. K., Goode, E. L., Goodman, M. T., Gross, J., Hansen, T. V. O., Harnett, P., Rookus, M., Heikkinen, T., Hein, R., Høgdall, C., Høgdall, E., Iversen, E. S., Jakubowska, A., Johnatty, S. E., Karlan, B. Y., Kauff, N. D., Kaye, S. B., Chenevix-Trench, G., Kelemen, L. E., Kiemeney, L. A., Kjaer, S. K., Lambrechts, D., LaPolla, J. P., Lázaro, C., Le, N. D., Leminen, A., Leunen, K., Levine, D. A., Lu, Y., Lundvall, L., Macgregor, S., Marees, T., Massuger, L. F., McLaughlin, J. R., Menon, U., Montagna, M., Moysich, K. B., Narod, S. A., Nathanson, K. L., Nedergaard, L., Ness, R. B., Nevanlinna, H., Nickels, S., Osorio, A., Paul, J., Pearce, C. L., Phelan, C. M., Pike, M. C., Radice, P., Rossing, M. A., Schildkraut, J. M., Sellers, T. A., Singer, C. F., Song, H., Stram, D. O., Sutphen, R., Lindblom, A., Terry, K. L., Tsai, Y. Y., Van Altena, A. M., Vergote, I., Vierkant, R. A., Vitonis, A. F., Walsh, C., Wang-Gohrke, S., Wappenschmidt, B., Wu, A. H., Ziogas, A., Berchuck, A. & Risch, H. A., Jun 1 2011, In: Clinical Cancer Research. 17, 11, p. 3742-3750 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    44 Scopus citations
  • Trends in the surgical management of epithelial ovarian cancer in East Anglia 1995-2006

    Lyratzopoulos, G., Newsome, H., Barbiere, J., Bolton, K., Wright, K., Kitchener, H. & Greenberg, D., May 2011, In: European Journal of Surgical Oncology. 37, 5, p. 435-441 7 p.

    Research output: Contribution to journalArticlepeer-review

    2 Scopus citations
  • 2010

    A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24

    Goode, E. L., Chenevix-Trench, G., Song, H., Ramus, S. J., Notaridou, M., Lawrenson, K., Widschwendter, M., Vierkant, R. A., Larson, M. C., Kjaer, S. K., Birrer, M. J., Berchuck, A., Schildkraut, J., Tomlinson, I., Kiemeney, L. A., Cook, L. S., Gronwald, J., Garcia-Closas, M., Gore, M. E., Campbell, I., & 92 othersWhittemore, A. S., Sutphen, R., Phelan, C., Anton-Culver, H., Pearce, C. L., Lambrechts, D., Rossing, M. A., Chang-Claude, J., Moysich, K. B., Goodman, M. T., Dörk, T., Nevanlinna, H., Ness, R. B., Rafnar, T., Hogdall, C., Hogdall, E., Fridley, B. L., Cunningham, J. M., Sieh, W., McGuire, V., Godwin, A. K., Cramer, D. W., Hernandez, D., Levine, D., Lu, K., Iversen, E. S., Palmieri, R. T., Houlston, R., Van Altena, A. M., Aben, K. K. H., Massuger, L. F. A. G., Brooks-Wilson, A., Kelemen, L. E., Le, N. D., Jakubowska, A., Lubinski, J., Medrek, K., Stafford, A., Easton, D. F., Tyrer, J., Bolton, K. L., Harrington, P., Eccles, D., Chen, A., Molina, A. N., Davila, B. N., Arango, H., Tsai, Y. Y., Chen, Z., Risch, H. A., McLaughlin, J., Narod, S. A., Ziogas, A., Brewster, W., Gentry-Maharaj, A., Menon, U., Wu, A. H., Stram, D. O., Pike, M. C., Beesley, J., Webb, P. M., Chen, X., Ekici, A. B., Thiel, F. C., Beckmann, M. W., Yang, H., Wentzensen, N., Lissowska, J., Fasching, P. A., Despierre, E., Amant, F., Vergote, I., Doherty, J., Hein, R., Wang-Gohrke, S., Lurie, G., Carney, M. E., Thompson, P. J., Runnebaum, I., Hillemanns, P., Dürst, M., Antonenkova, N., Bogdanova, N., Leminen, A., Butzow, R., Heikkinen, T., Stefansson, K., Sulem, P., Besenbacher, S., Sellers, T. A., Gayther, S. A. & Pharoah, P. D. P., Oct 2010, In: Nature Genetics. 42, 10, p. 874-879 6 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    300 Scopus citations
  • Assessment of automated image analysis of breast cancer tissue microarrays for epidemiologic studies

    Bolton, K. L., Garcia-Closas, M., Pfeiffer, R. M., Duggan, M. A., Howat, W. J., Hewitt, S. M., Yang, X. R., Cornelison, R., Anzick, S. L., Meltzer, P., Davis, S., Lenz, P., Figueroa, J. D., Pharoah, P. D. P. & Sherman, M. E., Apr 2010, In: Cancer Epidemiology Biomarkers and Prevention. 19, 4, p. 992-999 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    52 Scopus citations
  • Association between a germline OCA2 polymorphism at chromosome 15q13.1 and estrogen receptor-negative breast cancer survival

    Azzato, E. M., Tyrer, J., Fasching, P. A., Beckmann, M. W., Ekici, A. B., Schulz-Wendtland, R., Bojesen, S. E., Nordestgaard, B. G., Flyger, H., Milne, R. L., Arias, J. I., Menéndez, P., Benítez, J., Chang-Claude, J., Hein, R., Wang-Gohrke, S., Nevanlinna, H., Heikkinen, T., Aittomäki, K., Blomqvist, C., & 35 othersMargolin, S., Mannermaa, A., Kosma, V. M., Kataja, V., Beesley, J., Chen, X., Chenevix-Trench, G., Couch, F. J., Olson, J. E., Fredericksen, Z. S., Wang, X., Giles, G. G., Severi, G., Baglietto, L., Southey, M. C., Devilee, P., Tollenaar, R. A. E. M., Seynaeve, C., García-Closas, M., Lissowska, J., Sherman, M. E., Bolton, K. L., Hall, P., Czene, K., Cox, A., Brock, I. W., Elliott, G. C., Reed, M. W. R., Greenberg, D., Anton-Culver, H., Ziogas, A., Humphreys, M., Easton, D. F., Caporaso, N. E. & Pharoah, P. D. P., May 2010, In: Journal of the National Cancer Institute. 102, 9, p. 650-662 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    47 Scopus citations
  • Common variants at 19p13 are associated with susceptibility to ovarian cancer

    Bolton, K. L., Tyrer, J., Song, H., Ramus, S. J., Notaridou, M., Jones, C., Sher, T., Gentry-Maharaj, A., Wozniak, E., Tsai, Y. Y., Weidhaas, J., Paik, D., Van Den Berg, D. J., Stram, D. O., Pearce, C. L., Wu, A. H., Brewster, W., Anton-Culver, H., Ziogas, A., Narod, S. A., & 96 othersLevine, D. A., Kaye, S. B., Brown, R., Paul, J., Flanagan, J., Sieh, W., McGuire, V., Whittemore, A. S., Campbell, I., Gore, M. E., Lissowska, J., Yang, H. P., Medrek, K., Gronwald, J., Lubinski, J., Jakubowska, A., Le, N. D., Cook, L. S., Kelemen, L. E., Brook-Wilson, A., Massuger, L. F. A. G., Kiemeney, L. A., Aben, K. K. H., Van Altena, A. M., Houlston, R., Tomlinson, I., Palmieri, R. T., Moorman, P. G., Schildkraut, J., Iversen, E. S., Phelan, C., Vierkant, R. A., Cunningham, J. M., Goode, E. L., Fridley, B. L., Kruger-Kjaer, S., Blaeker, J., Hogdall, E., Hogdall, C., Gross, J., Karlan, B. Y., Ness, R. B., Edwards, R. P., Odunsi, K., Moyisch, K. B., Baker, J. A., Modugno, F., Heikkinenen, T., Butzow, R., Nevanlinna, H., Leminen, A., Bogdanova, N., Antonenkova, N., Doerk, T., Hillemanns, P., Dürst, M., Runnebaum, I., Thompson, P. J., Carney, M. E., Goodman, M. T., Lurie, G., Wang-Gohrke, S., Hein, R., Chang-Claude, J., Rossing, M. A., Cushing-Haugen, K. L., Doherty, J., Chen, C., Rafnar, T., Besenbacher, S., Sulem, P., Stefansson, K., Birrer, M. J., Terry, K. L., Hernandez, D., Cramer, D. W., Vergote, I., Amant, F., Lambrechts, D., Despierre, E., Fasching, P. A., Beckmann, M. W., Thiel, F. C., Ekici, A. B., Chen, X., Johnatty, S. E., Webb, P. M., Beesley, J., Chanock, S., Garcia-Closas, M., Sellers, T., Easton, D. F., Berchuck, A., Chenevix-Trench, G., Pharoah, P. D. P. & Gayther, S. A., Oct 2010, In: Nature Genetics. 42, 10, p. 880-884 5 p.

    Research output: Contribution to journalArticlepeer-review

    221 Scopus citations
  • Vascular endothelial growth factor gene polymorphisms and ovarian cancer survival

    Lose, F., Nagle, C. M., O'Mara, T., Batra, J., Bolton, K. L., Song, H., Ramus, S. J., Gentry-Maharaj, A., Menon, U., Gayther, S. A., Pharoah, P. D. P., Kedda, M. A. & Spurdle, A. B., Dec 2010, In: Gynecologic oncology. 119, 3, p. 479-483 5 p.

    Research output: Contribution to journalArticlepeer-review

    27 Scopus citations
  • 2009

    ADHD latent class clusters: DSM-IV subtypes and comorbidity

    Elia, J., Arcos-Burgos, M., Bolton, K. L., Ambrosini, P. J., Berrettini, W. & Muenke, M., Dec 30 2009, In: Psychiatry Research. 170, 2-3, p. 192-198 7 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    42 Scopus citations
  • A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2

    Song, H., Ramus, S. J., Tyrer, J., Bolton, K. L., Gentry-Maharaj, A., Wozniak, E., Anton-Culver, H., Chang-Claude, J., Cramer, D. W., DiCioccio, R., Dörk, T., Goode, E. L., Goodman, M. T., Schildkraut, J. M., Sellers, T., Baglietto, L., Beckmann, M. W., Beesley, J., Blaakaer, J., Carney, M. E., & 65 othersChanock, S., Chen, Z., Cunningham, J. M., Dicks, E., Doherty, J. A., Dürst, M., Ekici, A. B., Fenstermacher, D., Fridley, B. L., Giles, G., Gore, M. E., De Vivo, I., Hillemanns, P., Hogdall, C., Hogdall, E., Iversen, E. S., Jacobs, I. J., Jakubowska, A., Li, D., Lissowska, J., Lubiński, J., Lurie, G., McGuire, V., McLaughlin, J., Mȩdrek, K., Moorman, P. G., Moysich, K., Narod, S., Phelan, C., Pye, C., Risch, H., Runnebaum, I. B., Severi, G., Southey, M., Stram, D. O., Thiel, F. C., Terry, K. L., Tsai, Y. Y., Tworoger, S. S., Van Den Berg, D. J., Vierkant, R. A., Wang-Gohrke, S., Webb, P. M., Wilkens, L. R., Wu, A. H., Yang, H., Brewster, W., Ziogas, A., Houlston, R., Tomlinson, I., Whittemore, A. S., Rossing, M. A., Ponder, B. A. J., Pearce, C. L., Ness, R. B., Menon, U., Kjaer, S. K., Gronwald, J., Garcia-Closas, M., Fasching, P. A., Easton, D. F., Chenevix-Trench, G., Berchuck, A., Pharoah, P. D. P. & Gayther, S. A., Sep 2009, In: Nature Genetics. 41, 9, p. 996-1000 5 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    264 Scopus citations
  • Smoking, drinking and body weight after re-employment: Does unemployment experience and compensation make a difference?

    Bolton, K. L. & Rodriguez, E., 2009, In: BMC Public Health. 9, 77.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    41 Scopus citations
  • 2008

    Latent class subtyping of attention-deficit/hyperactivity disorder and comorbid conditions

    Acosta, M. T., Castellanos, F. X., Bolton, K. L., Balog, J. Z., Eagen, P., Nee, L., Jones, J., Palacio, L., Sarampote, C., Russell, H. F., Berg, K., Arcos-Burgos, M. & Muenke, M., Jul 2008, In: Journal of the American Academy of Child and Adolescent Psychiatry. 47, 7, p. 797-807 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    68 Scopus citations
  • 2006

    Pinoresinol: A lignol of plant origin serving for defense in a caterpillar

    Schroeder, F. C., Del Campo, M. L., Grant, J. B., Weibel, D. B., Smedley, S. R., Bolton, K. L., Meinwald, J. & Eisner, T., Oct 17 2006, In: Proceedings of the National Academy of Sciences of the United States of America. 103, 42, p. 15497-15501 5 p.

    Research output: Contribution to journalArticlepeer-review

    65 Scopus citations